Sangeeta Bhatia Health Sciences and Technology Massachusetts Institute of Technology Biography Publications Institution JoVE Articles Sangeeta Bhatia has not added a biography. If you are Sangeeta Bhatia and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Small Molecules for Human Hepatocyte Expansion and IPS Differentiation Nature Chemical Biology. Jun, 2013 | Pubmed ID: 23728495 Mitochondrial Localization and the Persistent Migration of Epithelial Cancer Cells Biophysical Journal. May, 2013 | Pubmed ID: 23663851 Geometric Control of Vascular Networks to Enhance Engineered Tissue Integration and Function Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23610423 Flow-based Pipeline for Systematic Modulation and Analysis of 3D Tumor Microenvironments Lab on a Chip. May, 2013 | Pubmed ID: 23563587 Mass-encoded Synthetic Biomarkers for Multiplexed Urinary Monitoring of Disease Nature Biotechnology. Jan, 2013 | Pubmed ID: 23242163 What is the Greatest Regulatory Challenge in the Translation of Biomaterials to the Clinic? Science Translational Medicine. Nov, 2012 | Pubmed ID: 23152323 In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria ACS Synthetic Biology. Oct, 2012 | Pubmed ID: 23097750 Genetic Circuits in Salmonella Typhimurium ACS Synthetic Biology. Oct, 2012 | Pubmed ID: 23097749 Bioengineering Methods for Analysis of Cells in Vitro Annual Review of Cell and Developmental Biology. 2012 | Pubmed ID: 23057744 A Combinatorial Extracellular Matrix Platform Identifies Cell-extracellular Matrix Interactions That Correlate with Metastasis Nature Communications. 2012 | Pubmed ID: 23047680 Critical Role for Lysyl Oxidase in Mesenchymal Stem Cell-driven Breast Cancer Malignancy Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 23033492 Identification and Characterization of Receptor-specific Peptides for SiRNA Delivery ACS Nano. Oct, 2012 | Pubmed ID: 22909216 Cancer Vulnerabilities Unveiled by Genomic Loss Cell. Aug, 2012 | Pubmed ID: 22901813 Targeted Tumor-penetrating SiRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4 Science Translational Medicine. Aug, 2012 | Pubmed ID: 22896676 The Challenges Posed by Cancer Heterogeneity Nature Biotechnology. Jul, 2012 | Pubmed ID: 22781679 Rapid Casting of Patterned Vascular Networks for Perfusable Engineered Three-dimensional Tissues Nature Materials. Jul, 2012 | Pubmed ID: 22751181 A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease Science Translational Medicine. Feb, 2012 | Pubmed ID: 22378926 Modeling Hepatitis C Virus Infection Using Human Induced Pluripotent Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308485 Expression of Paramyxovirus V Proteins Promotes Replication and Spread of Hepatitis C Virus in Cultures of Primary Human Fetal Liver Cells Hepatology (Baltimore, Md.). Dec, 2011 | Pubmed ID: 22144107 Bioresponsive Mesoporous Silica Nanoparticles for Triggered Drug Release Journal of the American Chemical Society. Dec, 2011 | Pubmed ID: 21981330 DNA-templated Assembly of Droplet-derived PEG Microtissues Lab on a Chip. Sep, 2011 | Pubmed ID: 21776518 Humanized Mice with Ectopic Artificial Liver Tissues Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21746904 Systematic Investigation of Genetic Vulnerabilities Across Cancer Cell Lines Reveals Lineage-specific Dependencies in Ovarian Cancer Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21746896 Nanoparticles That Communicate in Vivo to Amplify Tumour Targeting Nature Materials. Jul, 2011 | Pubmed ID: 21685903 Using C. Elegans to Identify the Protease Targets of Serpins in Vivo Methods in Enzymology. 2011 | Pubmed ID: 21683259 In-silico Patterning of Vascular Mesenchymal Cells in Three Dimensions PloS One. 2011 | Pubmed ID: 21633504 Nanoparticle-mediated Delivery of SiRNA Targeting Parp1 Extends Survival of Mice Bearing Tumors Derived from Brca1-deficient Ovarian Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Jan, 2011 | Pubmed ID: 21187397 Multiplexed, High-throughput Analysis of 3D Microtissue Suspensions Integrative Biology : Quantitative Biosciences from Nano to Macro. Oct, 2010 | Pubmed ID: 20820630 Ligand-clustered "patchy" Nanoparticles for Modulated Cellular Uptake and in Vivo Tumor Targeting Angewandte Chemie (International Ed. in English). Sep, 2010 | Pubmed ID: 20740515 Single Cell Trapping and DNA Damage Analysis Using Microwell Arrays Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534572 Microfluidics-integrated Time-lapse Imaging for Analysis of Cellular Dynamics Integrative Biology : Quantitative Biosciences from Nano to Macro. Jun, 2010 | Pubmed ID: 20532320 Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference Journal of the American Chemical Society. Jun, 2010 | Pubmed ID: 20518524 Targeting of Drugs and Nanoparticles to Tumors The Journal of Cell Biology. Mar, 2010 | Pubmed ID: 20231381 Cooperative Nanoparticles for Tumor Detection and Photothermally Triggered Drug Delivery Advanced Materials (Deerfield Beach, Fla.). Feb, 2010 | Pubmed ID: 20217810 The Pipeline Still Leaks and More Than You Think: a Status Report on Gender Diversity in Biomedical Engineering Annals of Biomedical Engineering. May, 2010 | Pubmed ID: 20162356 Persistent Hepatitis C Virus Infection in Microscale Primary Human Hepatocyte Cultures Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133632 Real-time Imaging of Hepatitis C Virus Infection Using a Fluorescent Cell-based Reporter System Nature Biotechnology. Feb, 2010 | Pubmed ID: 20118917 Cooperative Nanomaterial System to Sensitize, Target, and Treat Tumors Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20080556 Tissue-specific Gene Delivery Via Nanoparticle Coating Biomaterials. Feb, 2010 | Pubmed ID: 19850333 SERS-Coded Gold Nanorods As a Multifunctional Platform for Densely Multiplexed Near-Infrared Imaging and Photothermal Heating Advanced Materials (Deerfield Beach, Fla.). Apr, 2009 | Pubmed ID: 20174478 Silicon Nanoparticles As Hyperpolarized Magnetic Resonance Imaging Agents ACS Nano. Dec, 2009 | Pubmed ID: 19950973 Urinary Tract Infection in a Healthy 10-year-old Boy: an Occult Etiology Pediatric Emergency Care. Sep, 2009 | Pubmed ID: 19755897 Functional Delivery of SiRNA in Mice Using Dendriworms ACS Nano. Sep, 2009 | Pubmed ID: 19673534 Microenvironmental Regulation of the Sinusoidal Endothelial Cell Phenotype in Vitro Hepatology (Baltimore, Md.). Sep, 2009 | Pubmed ID: 19585615 Differential Proteomics Analysis of the Surface Heterogeneity of Dextran Iron Oxide Nanoparticles and the Implications for Their in Vivo Clearance Biomaterials. Aug, 2009 | Pubmed ID: 19394687 Computationally Guided Photothermal Tumor Therapy Using Long-circulating Gold Nanorod Antennas Cancer Research. May, 2009 | Pubmed ID: 19366797 Systematic Surface Engineering of Magnetic Nanoworms for in Vivo Tumor Targeting Small (Weinheim an Der Bergstrasse, Germany). Mar, 2009 | Pubmed ID: 19263431 Biodegradable Luminescent Porous Silicon Nanoparticles for in Vivo Applications Nature Materials. Apr, 2009 | Pubmed ID: 19234444 Statistical Dynamics of Flowing Red Blood Cells by Morphological Image Processing PLoS Computational Biology. Feb, 2009 | Pubmed ID: 19214200 Modulation of Hepatocyte Phenotype in Vitro Via Chemomechanical Tuning of Polyelectrolyte Multilayers Biomaterials. Feb, 2009 | Pubmed ID: 19046762 Modeling Molecular and Cellular Aspects of Human Disease Using the Nematode Caenorhabditis Elegans Pediatric Research. Jan, 2009 | Pubmed ID: 18852689 The Compatibility of Hepatocytes with Chemically Modified Porous Silicon with Reference to in Vitro Biosensors Biomaterials. Jan, 2009 | Pubmed ID: 18845334 Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging Advanced Materials (Deerfield Beach, Fla.). May, 2008 | Pubmed ID: 21687830 Micellar Hybrid Nanoparticles for Simultaneous Magnetofluorescent Imaging and Drug Delivery Angewandte Chemie (International Ed. in English). 2008 | Pubmed ID: 18696519 Protease-triggered Unveiling of Bioactive Nanoparticles Small (Weinheim an Der Bergstrasse, Germany). Sep, 2008 | Pubmed ID: 18690639 T-cadherin Modulates Hepatocyte Functions in Vitro FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2008 | Pubmed ID: 18635739 In Vivo Tumor Cell Targeting with "click" Nanoparticles Bioconjugate Chemistry. Aug, 2008 | Pubmed ID: 18611045 Combinatorial Signaling Microenvironments for Studying Stem Cell Fate Stem Cells and Development. Feb, 2008 | Pubmed ID: 18271698 Microscale Culture of Human Liver Cells for Drug Development Nature Biotechnology. Jan, 2008 | Pubmed ID: 18026090 Measuring Growth and Gene Expression Dynamics of Tumor-Targeted S. Typhimurium Bacteria Tal Danino*1, Arthur Prindle*2, Jeff Hasty2,3,4, Sangeeta Bhatia1,5,6,7,8 1Health Sciences and Technology, Massachusetts Institute of Technology, 2Department of Bioengineering, University of California, San Diego, 3Biocircuits Institute, University of California, San Diego, 4Molecular Biology Section, Division of Biological Science, University of California, San Diego, 5Broad Institute of Harvard and MIT, 6Department of Medicine, Brigham and Women's Hospital, 7Electrical Engineering and Computer Science and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 8Howard Hughes Medical Institute JoVE 50540 Immunology and Infection
Measuring Growth and Gene Expression Dynamics of Tumor-Targeted S. Typhimurium Bacteria Tal Danino*1, Arthur Prindle*2, Jeff Hasty2,3,4, Sangeeta Bhatia1,5,6,7,8 1Health Sciences and Technology, Massachusetts Institute of Technology, 2Department of Bioengineering, University of California, San Diego, 3Biocircuits Institute, University of California, San Diego, 4Molecular Biology Section, Division of Biological Science, University of California, San Diego, 5Broad Institute of Harvard and MIT, 6Department of Medicine, Brigham and Women's Hospital, 7Electrical Engineering and Computer Science and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 8Howard Hughes Medical Institute JoVE 50540 Immunology and Infection
