Sarah E. Blutt Departments of Molecular Virology and Microbiology and Medicine Baylor College of Medicine Biography Publications Institution JoVE Articles Sarah E. Blutt has not added a biography. If you are Sarah E. Blutt and would like to personalize this page please email our Author Liaison for assistance. Publications Looking on the Horizon; Potential and Unique Approaches to Developing Radiation Countermeasures for Deep Space Travel Life Sciences in Space Research. Nov, 2022 | Pubmed ID: 36336356 Organoid Models for Infectious Disease Annual Review of Medicine. Jan, 2022 | Pubmed ID: 34644153 Single-cell Sequencing of Rotavirus-infected Intestinal Epithelium Reveals Cell-type Specific Epithelial Repair and Tuft Cell Infection Proceedings of the National Academy of Sciences of the United States of America. 11, 2021 | Pubmed ID: 34732579 Drivers of Transcriptional Variance in Human Intestinal Epithelial Organoids Physiological Genomics. Nov, 2021 | Pubmed ID: 34612061 Use of Human Tissue Stem Cell-derived Organoid Cultures to Model Enterohepatic Circulation American Journal of Physiology. Gastrointestinal and Liver Physiology. 09, 2021 | Pubmed ID: 34288725 Telomere Dysfunction Instigates Inflammation in Inflammatory Bowel Disease Proceedings of the National Academy of Sciences of the United States of America. 07, 2021 | Pubmed ID: 34253611 Organoids to Dissect Gastrointestinal Virus-Host Interactions: What Have We Learned? Viruses. 05, 2021 | Pubmed ID: 34071878 Protein-Functionalized Poly(ethylene Glycol) Hydrogels As Scaffolds for Monolayer Organoid Culture Tissue Engineering. Part C, Methods. 01, 2021 | Pubmed ID: 33334213 Intestinal Stem Cell-derived Enteroids from Morbidly Obese Patients Preserve Obesity-related Phenotypes: Elevated Glucose Absorption and Gluconeogenesis Molecular Metabolism. 02, 2021 | Pubmed ID: 33246140 Enteropathogenic Escherichia Coli Infection in Cancer and Immunosuppressed Patients Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. 05, 2021 | Pubmed ID: 32930708 Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration After Bacterial Cytotoxin Injury IScience. Oct, 2020 | Pubmed ID: 33089106 Enteroaggregative E. Coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection PLoS Pathogens. 09, 2020 | Pubmed ID: 32986782 Telomere Dysfunction Activates YAP1 to Drive Tissue Inflammation Nature Communications. 09, 2020 | Pubmed ID: 32958778 Human Norovirus Exhibits Strain-specific Sensitivity to Host Interferon Pathways in Human Intestinal Enteroids Proceedings of the National Academy of Sciences of the United States of America. 09, 2020 | Pubmed ID: 32907944 Models of the Small Intestine: Engineering Challenges and Engineering Solutions Tissue Engineering. Part B, Reviews. 08, 2020 | Pubmed ID: 32046599 Gut Bacterial Bouncers: Keeping Viral Pathogens out of the Epithelium Cell Host & Microbe. 11, 2019 | Pubmed ID: 31726023 Use of Organoids to Study Regenerative Responses to Intestinal Damage American Journal of Physiology. Gastrointestinal and Liver Physiology. 12, 2019 | Pubmed ID: 31589468 Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges Viruses. Jul, 2019 | Pubmed ID: 31336765 The Next MacGyver: A Platform to Study Intestinal Organoids Using High-Throughput Computer-Driven Microinjection Cellular and Molecular Gastroenterology and Hepatology. 2018 | Pubmed ID: 30182047 Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases Cellular and Molecular Gastroenterology and Hepatology. Mar, 2018 | Pubmed ID: 29675450 Human Organoid Cultures: Transformative New Tools for Human Virus Studies Current Opinion in Virology. 04, 2018 | Pubmed ID: 29656244 Novel Segment- and Host-Specific Patterns of Enteroaggregative Adherence to Human Intestinal Enteroids MBio. 02, 2018 | Pubmed ID: 29463660 Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation Cell Reports. 01, 2018 | Pubmed ID: 29386123 Gastrointestinal Microphysiological Systems Experimental Biology and Medicine (Maywood, N.J.). 10, 2017 | Pubmed ID: 28534432 Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections Methods in Molecular Biology (Clifton, N.J.). Mar, 2017 | Pubmed ID: 28361480 A Paradox of Transcriptional and Functional Innate Interferon Responses of Human Intestinal Enteroids to Enteric Virus Infection Proceedings of the National Academy of Sciences of the United States of America. 01, 2017 | Pubmed ID: 28069942 Replication of Human Noroviruses in Stem Cell-derived Human Enteroids Science (New York, N.Y.). 09, 2016 | Pubmed ID: 27562956 Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology The Journal of Biological Chemistry. Feb, 2016 | Pubmed ID: 26677228 Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology Journal of Virology. 01, 2016 | Pubmed ID: 26446608 Human Enteroids As an Ex-vivo Model of Host-pathogen Interactions in the Gastrointestinal Tract Experimental Biology and Medicine (Maywood, N.J.). Sep, 2014 | Pubmed ID: 24719375 FoxP3+ Regulatory T Cells Are Not Important for Rotavirus Clearance or the Early Antibody Response to Rotavirus Microbes and Infection. Jan, 2014 | Pubmed ID: 24095866 The Gastrointestinal Frontier: IgA and Viruses Frontiers in Immunology. Nov, 2013 | Pubmed ID: 24348474 Lymphotoxin Alpha-deficient Mice Clear Persistent Rotavirus Infection After Local Generation of Mucosal IgA Journal of Virology. Jan, 2013 | Pubmed ID: 23097456 IgA is Important for Clearance and Critical for Protection from Rotavirus Infection Mucosal Immunology. Nov, 2012 | Pubmed ID: 22739233 Host Response to Probiotics Determined by Nutritional Status of Rotavirus-infected Neonatal Mice Journal of Pediatric Gastroenterology and Nutrition. Sep, 2012 | Pubmed ID: 22343914 Probiotics Stimulate Enterocyte Migration and Microbial Diversity in the Neonatal Mouse Intestine FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2012 | Pubmed ID: 22267340 Immune Mediators of Rotavirus Antigenemia Clearance in Mice Journal of Virology. Aug, 2011 | Pubmed ID: 21593155 Differential Requirements for T Cells in Viruslike Particle- and Rotavirus-induced Protective Immunity Journal of Virology. Mar, 2008 | Pubmed ID: 18184712 Rotavirus Antigenemia in Children is Associated with Viremia PLoS Medicine. Apr, 2007 | Pubmed ID: 17439294 Expression of Rotavirus NSP4 Alters the Actin Network Organization Through the Actin Remodeling Protein Cofilin Journal of Virology. Apr, 2007 | Pubmed ID: 17229686 Rotavirus: to the Gut and Beyond! Current Opinion in Gastroenterology. Jan, 2007 | Pubmed ID: 17133083 Rotavirus Infection Enhances Lipopolysaccharide-induced Intussusception in a Mouse Model Journal of Virology. Dec, 2006 | Pubmed ID: 17005639 Active Viremia in Rotavirus-infected Mice Journal of Virology. Jul, 2006 | Pubmed ID: 16775359 Host, Viral, and Vaccine Factors That Determine Protective Efficacy Induced by Rotavirus and Virus-like Particles (VLPs) Vaccine. Feb, 2006 | Pubmed ID: 16191453 The VP7 Outer Capsid Protein of Rotavirus Induces Polyclonal B-cell Activation Journal of Virology. Jul, 2004 | Pubmed ID: 15194774 Kinetics of Rotavirus Infection in Mice Are Not Altered in a Ground-based Model of Spaceflight Aviation, Space, and Environmental Medicine. Mar, 2004 | Pubmed ID: 15018288 Rotavirus Antigenaemia and Viraemia: a Common Event? Lancet (London, England). Nov, 2003 | Pubmed ID: 14602437 Early Response to Rotavirus Infection Involves Massive B Cell Activation Journal of Immunology (Baltimore, Md. : 1950). Jun, 2002 | Pubmed ID: 12023371 VLA-2 (alpha2beta1) Integrin Promotes Rotavirus Entry into Cells but is Not Necessary for Rotavirus Attachment Journal of Virology. Feb, 2002 | Pubmed ID: 11773387 Establishing 3D Endometrial Organoids from the Mouse Uterus Suni Tang1,2, Sydney E. Parks1,2, Zian Liao1,2, Dominique I. Cope1,2, Sarah E. Blutt3, Diana Monsivais1,2 1Department of Pathology & Immunology, Baylor College of Medicine, 2Center for Drug Discovery, Baylor College of Medicine, 3Departments of Molecular Virology and Microbiology and Medicine, Baylor College of Medicine JoVE 64448 Biology
Establishing 3D Endometrial Organoids from the Mouse Uterus Suni Tang1,2, Sydney E. Parks1,2, Zian Liao1,2, Dominique I. Cope1,2, Sarah E. Blutt3, Diana Monsivais1,2 1Department of Pathology & Immunology, Baylor College of Medicine, 2Center for Drug Discovery, Baylor College of Medicine, 3Departments of Molecular Virology and Microbiology and Medicine, Baylor College of Medicine JoVE 64448 Biology