In JoVE (1)
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Articles by Sarah L. Gael in JoVE
Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets Helen Tran1, Sarah L. Gael1, Michael D. Connolly1, Ronald N. Zuckermann1 1Molecular Foundry, Lawrence Berkeley National Laboratory A simple and general manual peptoid synthesis method involving basic equipment and commercially available reagents is outlined, enabling peptoids to be easily synthesized in most laboratories. The synthesis, purification and characterization of an amphiphilic peptoid 36mer is described, as well as its self-assembly into highly-ordered nanosheets.