Satoru Arata Institute of Molecular Oncology Showa University Biography Publications Institution JoVE Articles Satoru Arata has not added a biography. If you are Satoru Arata and would like to personalize this page please email our Author Liaison for assistance. Publications Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation Molecular Cancer Research : MCR. Jul, 2017 | Pubmed ID: 28289161 Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation Molecular Cancer Therapeutics. Dec, 2016 | Pubmed ID: 27612490 Continuous Intake of the Chaga Mushroom (Inonotus Obliquus) Aqueous Extract Suppresses Cancer Progression and Maintains Body Temperature in Mice Heliyon. May, 2016 | Pubmed ID: 27441282 A New Xist Allele Driven by a Constitutively Active Promoter is Dominated by Xist Locus Environment and Exhibits the Parent-of-origin Effects Development (Cambridge, England). Dec, 2015 | Pubmed ID: 26511926 Localization and Osteoblastic Differentiation Potential of Neural Crest-derived Cells in Oral Tissues of Adult Mice Biochemical and Biophysical Research Communications. Sep, 2015 | Pubmed ID: 26225748 A Phox2b BAC Transgenic Rat Line Useful for Understanding Respiratory Rhythm Generator Neural Circuitry PloS One. 2015 | Pubmed ID: 26147470 Ghrelin Suppresses Proliferation of Fetal Neural Progenitor Cells, and Induces Their Differentiation into Neurons Peptides. Jul, 2015 | Pubmed ID: 25828736 Calpastatin Counteracts Pathological Angiogenesis by Inhibiting Suppressor of Cytokine Signaling 3 Degradation in Vascular Endothelial Cells Circulation Research. Mar, 2015 | Pubmed ID: 25648699 Comparison of Expression and Proliferative Effect of Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) and Its Receptors on Human Astrocytoma Cell Lines Journal of Molecular Neuroscience : MN. Nov, 2014 | Pubmed ID: 25091859 Impaired Response to Hypoxia in the Respiratory Center is a Major Cause of Neonatal Death of the PACAP-knockout Mouse The European Journal of Neuroscience. Feb, 2013 | Pubmed ID: 23136967 IL-6 and PACAP Receptor Expression and Localization After Global Brain Ischemia in Mice Journal of Molecular Neuroscience : MN. Nov, 2012 | Pubmed ID: 22669509 M-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-cadherin Disorganization and Atherosclerosis Circulation. Dec, 2011 | Pubmed ID: 22064597 Dietary Cholesterol Reduces Plasma Triacylglycerol in Apolipoprotein E-null Mice: Suppression of Lipin-1 and -2 in the Glycerol-3-phosphate Pathway PloS One. 2011 | Pubmed ID: 21857965 Role of PACAP in Neural Stem/progenitor Cell and Astrocyte--from Neural Development to Neural Repair Current Pharmaceutical Design. 2011 | Pubmed ID: 21524256 Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Stimulates Proliferation of Reactive Astrocytes in Vitro Journal of Molecular Neuroscience : MN. Jan, 2011 | Pubmed ID: 20574684 Group III Secreted Phospholipase A2 Regulates Epididymal Sperm Maturation and Fertility in Mice The Journal of Clinical Investigation. May, 2010 | Pubmed ID: 20424323 Central Respiratory Failure in a Mouse Model Depends on the Genetic Background of the Host Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20217313 Loss of Pre-inspiratory Neuron Synchroneity in Mice with DSCAM Deficiency Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20217312 Depletion of Selenoprotein GPx4 in Spermatocytes Causes Male Infertility in Mice The Journal of Biological Chemistry. Nov, 2009 | Pubmed ID: 19783653 DSCAM Deficiency Causes Loss of Pre-inspiratory Neuron Synchroneity and Perinatal Death The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2009 | Pubmed ID: 19261893 Transient Increase in Plasma Oxidized LDL During the Progression of Atherosclerosis in Apolipoprotein E Knockout Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2009 | Pubmed ID: 18988894 Visualization of Ghrelin-producing Neurons in the Hypothalamic Arcuate Nucleus Using Ghrelin-EGFP Transgenic Mice Regulatory Peptides. Jan, 2008 | Pubmed ID: 17945362 Impaired Mast Cell Maturation and Degranulation and Attenuated Allergic Responses in Ndrg1-deficient Mice Journal of Immunology (Baltimore, Md. : 1950). Jun, 2007 | Pubmed ID: 17513753 Generation of Muscle Aquaporin 4 Overexpressing Transgenic Mouse: Its Characterization at RNA and Protein Levels Including Freeze-fracture Study Micron (Oxford, England : 1993). 2007 | Pubmed ID: 16820300 Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality Because of Lung Dysfunction The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 17008322 Pleiotropic Functions of PACAP in the CNS: Neuroprotection and Neurodevelopment Annals of the New York Academy of Sciences. Jul, 2006 | Pubmed ID: 16888224 Adiponectin Plays an Important Role in Efficient Energy Usage Under Energy Shortage Biochimica Et Biophysica Acta. Jul, 2006 | Pubmed ID: 16815093 Histamine Type 1 Receptor Deficiency Reduces Airway Inflammation in a Murine Asthma Model International Archives of Allergy and Immunology. 2006 | Pubmed ID: 16685135 The Testicular Fatty Acid Binding Protein PERF15 Regulates the Fate of Germ Cells in PERF15 Transgenic Mice Development, Growth & Differentiation. Jan, 2005 | Pubmed ID: 15740583 Pituitary Adenylate Cyclase-activating Polypeptide Promotes Differentiation of Mouse Neural Stem Cells into Astrocytes Regulatory Peptides. Mar, 2005 | Pubmed ID: 15620424 In Vitro Visualization of Respiratory Neuron Activity in the Newborn Mouse Ventral Medulla Brain Research. Developmental Brain Research. Nov, 2004 | Pubmed ID: 15527896 Pbx3 Deficiency Results in Central Hypoventilation The American Journal of Pathology. Oct, 2004 | Pubmed ID: 15466398 Tlx3 and Tlx1 Are Post-mitotic Selector Genes Determining Glutamatergic over GABAergic Cell Fates Nature Neuroscience. May, 2004 | Pubmed ID: 15064766 A Transgenic Mouse Model for the Detailed Morphological Study of Astrocytes Neuroscience Research. Dec, 2003 | Pubmed ID: 14630350 Suppression of Thermotolerance in Mumps Virus-infected Cells is Caused by Lack of HSP27 Induction Contributed by STAT-1 The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12917439 Expression of the Receptor for Pituitary Adenylate Cyclase-activating Polypeptide (PAC1-R) in Reactive Astrocytes Brain Research. Molecular Brain Research. Jul, 2003 | Pubmed ID: 12824050 Reduced Postischemic Apoptosis in the Hippocampus of Mice Deficient in Interleukin-1 The Journal of Comparative Neurology. Jun, 2002 | Pubmed ID: 12012430 Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure Toshimitsu Yamaoka1, Motoi Ohba1, Satoru Arata1,2, Tohru Ohmori1 1Institute of Molecular Oncology, Showa University, 2Center for Biotechnology, Showa University JoVE 55967 Cancer Research
Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure Toshimitsu Yamaoka1, Motoi Ohba1, Satoru Arata1,2, Tohru Ohmori1 1Institute of Molecular Oncology, Showa University, 2Center for Biotechnology, Showa University JoVE 55967 Cancer Research
