Schahram Akbarian Department of Neuroscience and Friedman Brain Institute Icahn School of Medicine at Mount Sinai Biography Publications Institution JoVE Articles Schahram Akbarian has not added a biography. If you are Schahram Akbarian and would like to personalize this page please email our Author Liaison for assistance. Publications Comprehensive Identification of Somatic Nucleotide Variants in Human Brain Tissue Genome Biology. Mar, 2021 | Pubmed ID: 33781308 Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection Stem Cell Reports. 03, 2021 | Pubmed ID: 33636110 Parsing the Functional Impact of Noncoding Genetic Variants in the Brain Epigenome Biological Psychiatry. Jan, 2021 | Pubmed ID: 33131715 Common Genetic Variation in Humans Impacts Susceptibility to SARS-CoV-2 Infection BioRxiv : the Preprint Server for Biology. Sep, 2020 | Pubmed ID: 32995783 A Prefrontal-paraventricular Thalamus Circuit Requires Juvenile Social Experience to Regulate Adult Sociability in Mice Nature Neuroscience. 10, 2020 | Pubmed ID: 32868932 Genotype-phenotype Correlation at Codon 1740 of SETD2 American Journal of Medical Genetics. Part A. 09, 2020 | Pubmed ID: 32710489 Epigenetic Clocks in Schizophrenia: Promising Biomarkers, Foggy Clockwork Biological Psychiatry. 08, 2020 | Pubmed ID: 32674842 Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells Advances in Neurobiology. 2020 | Pubmed ID: 32578147 A Computational Tool (H-MAGMA) for Improved Prediction of Brain-disorder Risk Genes by Incorporating Brain Chromatin Interaction Profiles Nature Neuroscience. 04, 2020 | Pubmed ID: 32152537 Prefrontal Parvalbumin Interneurons Require Juvenile Social Experience to Establish Adult Social Behavior Nature Communications. 02, 2020 | Pubmed ID: 32081848 A Chromosomal Connectome for Psychiatric and Metabolic Risk Variants in Adult Dopaminergic Neurons Genome Medicine. 02, 2020 | Pubmed ID: 32075678 Special Volume: The Genomics and Epigenomics of Schizophrenia Schizophrenia Research. 03, 2020 | Pubmed ID: 31813801 CRISPR-based Functional Evaluation of Schizophrenia Risk Variants Schizophrenia Research. 03, 2020 | Pubmed ID: 31277978 Use of the Epigenetic Toolbox to Contextualize Common Variants Associated with Schizophrenia Risk Dialogues in Clinical Neuroscience. 12, 2019 | Pubmed ID: 31949408 Chromatin Profiling of Cortical Neurons Identifies Individual Epigenetic Signatures in Schizophrenia Translational Psychiatry. 10, 2019 | Pubmed ID: 31624234 CommonMind Consortium Provides Transcriptomic and Epigenomic Data for Schizophrenia and Bipolar Disorder Scientific Data. 09, 2019 | Pubmed ID: 31551426 In Vivo Epigenetic Editing of Sema6a Promoter Reverses Transcallosal Dysconnectivity Caused by C11orf46/Arl14ep Risk Gene Nature Communications. 09, 2019 | Pubmed ID: 31511512 Metabolome Signature of Autism in the Human Prefrontal Cortex Communications Biology. 2019 | Pubmed ID: 31263778 Spatial Genome Exploration in the Context of Cognitive and Neurological Disease Current Opinion in Neurobiology. 12, 2019 | Pubmed ID: 31255842 Epigenetic-genetic Chromatin Footprinting Identifies Novel and Subject-specific Genes Active in Prefrontal Cortex Neurons FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 07, 2019 | Pubmed ID: 30970224 Comprehensive Functional Genomic Resource and Integrative Model for the Human Brain Science (New York, N.Y.). 12, 2018 | Pubmed ID: 30545857 Neuron-specific Signatures in the Chromosomal Connectome Associated with Schizophrenia Risk Science (New York, N.Y.). 12, 2018 | Pubmed ID: 30545851 Lipidome Alterations in Human Prefrontal Cortex During Development, Aging, and Cognitive Disorders Molecular Psychiatry. Aug, 2018 | Pubmed ID: 30089790 Evaluation of Chromatin Accessibility in Prefrontal Cortex of Individuals with Schizophrenia Nature Communications. 08, 2018 | Pubmed ID: 30087329 Cell-specific Histone Modification Maps in the Human Frontal Lobe Link Schizophrenia Risk to the Neuronal Epigenome Nature Neuroscience. 08, 2018 | Pubmed ID: 30038276 Chromosomal Conformations and Epigenomic Regulation in Schizophrenia Progress in Molecular Biology and Translational Science. 2018 | Pubmed ID: 29933951 Activity-Induced Regulation of Synaptic Strength Through the Chromatin Reader L3mbtl1 Cell Reports. 06, 2018 | Pubmed ID: 29898393 Landscape of Conditional EQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS American Journal of Human Genetics. 06, 2018 | Pubmed ID: 29805045 Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells Frontiers in Pediatrics. 2018 | Pubmed ID: 29666786 Allele-specific Expression in a Family Quartet with Autism Reveals Mono-to-biallelic Switch and Novel Transcriptional Processes of Autism Susceptibility Genes Scientific Reports. 03, 2018 | Pubmed ID: 29523860 MEF2C Transcription Factor is Associated with the Genetic and Epigenetic Risk Architecture of Schizophrenia and Improves Cognition in Mice Molecular Psychiatry. 01, 2018 | Pubmed ID: 28115742 Antipsychotic-induced Hdac2 Transcription Via NF-κB Leads to Synaptic and Cognitive Side Effects Nature Neuroscience. Sep, 2017 | Pubmed ID: 28783139 Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in HiPSC-Derived NPCs, Neurons, and Astrocytes Stem Cell Reports. 08, 2017 | Pubmed ID: 28757163 The Epigenomics of Schizophrenia, in the Mouse American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. Sep, 2017 | Pubmed ID: 28699694 The Methyltransferase SETDB1 Regulates a Large Neuron-specific Topological Chromatin Domain Nature Genetics. Aug, 2017 | Pubmed ID: 28671686 Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2 Biological Psychiatry. Dec, 2017 | Pubmed ID: 28577753 Phf8 Loss Confers Resistance to Depression-like and Anxiety-like Behaviors in Mice Nature Communications. 05, 2017 | Pubmed ID: 28485378 Intersection of Diverse Neuronal Genomes and Neuropsychiatric Disease: The Brain Somatic Mosaicism Network Science (New York, N.Y.). 04, 2017 | Pubmed ID: 28450582 Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue Biological Psychiatry. 01, 2017 | Pubmed ID: 27113501 Spatial Genome Organization and Cognition Nature Reviews. Neuroscience. 11, 2016 | Pubmed ID: 27708356 Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism PLoS Biology. Sep, 2016 | Pubmed ID: 27685936 Longitudinal Assessment of Neuronal 3D Genomes in Mouse Prefrontal Cortex Nature Communications. 09, 2016 | Pubmed ID: 27597321 Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 12, 2016 | Pubmed ID: 27485686 Insulin-like Growth Factor 1 for Healthy Spines and Healthy Minds? Biological Psychiatry. 08, 2016 | Pubmed ID: 27468627 Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research Biological Psychiatry. 07, 2016 | Pubmed ID: 27346079 DNA Methylation Signatures of Early Childhood Malnutrition Associated With Impairments in Attention and Cognition Biological Psychiatry. 11, 2016 | Pubmed ID: 27184921 Understanding the Genetic Liability to Schizophrenia Through the Neuroepigenome Schizophrenia Research. 11, 2016 | Pubmed ID: 26827128 NeuN+ Neuronal Nuclei in Non-human Primate Prefrontal Cortex and Subcortical White Matter After Clozapine Exposure Schizophrenia Research. Feb, 2016 | Pubmed ID: 26776227 Back to the Past in Schizophrenia Genomics Nature Neuroscience. Jan, 2016 | Pubmed ID: 26713739 Pharmacological Modulation of Astrocytes and the Role of Cell Type-specific Histone Modifications for the Treatment of Mood Disorders Current Opinion in Pharmacology. Feb, 2016 | Pubmed ID: 26515273 Epigenetic Basis of Mental Illness The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10, 2016 | Pubmed ID: 26450593 Chemogenetic Inactivation of Dorsal Anterior Cingulate Cortex Neurons Disrupts Attentional Behavior in Mouse Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Mar, 2016 | Pubmed ID: 26224620 RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression PloS One. 2015 | Pubmed ID: 26636579 Prefrontal Cortex and Social Cognition in Mouse and Man Frontiers in Psychology. 2015 | Pubmed ID: 26635701 The PsychENCODE Project Nature Neuroscience. Dec, 2015 | Pubmed ID: 26605881 CHRNA7 and CHRFAM7A: Psychosis and Smoking? Blame the Neighbors! The American Journal of Psychiatry. Nov, 2015 | Pubmed ID: 26575444 DNA Methylation Levels of α-synuclein Intron 1 in the Aging Brain Neurobiology of Aging. Dec, 2015 | Pubmed ID: 26422361 Critical Role of Histone Turnover in Neuronal Transcription and Plasticity Neuron. Jul, 2015 | Pubmed ID: 26139371 Quantifying Polymorphism and Divergence from Epigenetic Data: a Framework for Inferring the Action of Selection Frontiers in Genetics. 2015 | Pubmed ID: 26074949 MiR-10b-5p Expression in Huntington's Disease Brain Relates to Age of Onset and the Extent of Striatal Involvement BMC Medical Genomics. Mar, 2015 | Pubmed ID: 25889241 Cognition and Mood-related Behaviors in L3mbtl1 Null Mutant Mice PloS One. 2015 | Pubmed ID: 25849281 Interneuron Epigenomes During the Critical Period of Cortical Plasticity: Implications for Schizophrenia Neurobiology of Learning and Memory. Oct, 2015 | Pubmed ID: 25849095 Neuronal Kmt2a/Mll1 Histone Methyltransferase is Essential for Prefrontal Synaptic Plasticity and Working Memory The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2015 | Pubmed ID: 25834037 Transcriptional Regulation of GAD1 GABA Synthesis Gene in the Prefrontal Cortex of Subjects with Schizophrenia Schizophrenia Research. Sep, 2015 | Pubmed ID: 25458568 Epigenetics and Sex Differences in the Brain: A Genome-wide Comparison of Histone-3 Lysine-4 Trimethylation (H3K4me3) in Male and Female Mice Experimental Neurology. Jun, 2015 | Pubmed ID: 25131640 Conserved Higher-order Chromatin Regulates NMDA Receptor Gene Expression and Cognition Neuron. Dec, 2014 | Pubmed ID: 25467983 A Role for Noncoding Variation in Schizophrenia Cell Reports. Nov, 2014 | Pubmed ID: 25453756 The Future of Neuroepigenetics in the Human Brain Progress in Molecular Biology and Translational Science. 2014 | Pubmed ID: 25410546 Epigenetic Mechanisms in Schizophrenia Dialogues in Clinical Neuroscience. Sep, 2014 | Pubmed ID: 25364289 Analytical Tools and Current Challenges in the Modern Era of Neuroepigenomics Nature Neuroscience. Nov, 2014 | Pubmed ID: 25349914 Regulation of Histone H3K4 Methylation in Brain Development and Disease Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Sep, 2014 | Pubmed ID: 25135975 Chromatin-bound RNA and the Neurobiology of Psychiatric Disease Neuroscience. Apr, 2014 | Pubmed ID: 23831425 The Genome in Three Dimensions: A New Frontier in Human Brain Research Biological Psychiatry. Aug, 2013 | Pubmed ID: 23958183 Conserved Chromosome 2q31 Conformations Are Associated with Transcriptional Regulation of GAD1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2013 | Pubmed ID: 23864674 The Neuroepigenetics of Suicide The American Journal of Psychiatry. May, 2013 | Pubmed ID: 23632831 Epigenetic and Post-transcriptional Dysregulation of Gene Expression in Schizophrenia and Related Disease Neurobiology of Disease. Dec, 2011 | Pubmed ID: 22182689 Epigenetic Signatures of Autism: Trimethylated H3K4 Landscapes in Prefrontal Neurons Archives of General Psychiatry. Nov, 2011 | Pubmed ID: 22065254 Advancing Drug Discovery for Schizophrenia Annals of the New York Academy of Sciences. Oct, 2011 | Pubmed ID: 22032400 Balancing Histone Methylation Activities in Psychiatric Disorders Trends in Molecular Medicine. Jul, 2011 | Pubmed ID: 21429800 Setdb1-mediated Histone H3K9 Hypermethylation in Neurons Worsens the Neurological Phenotype of Mecp2-deficient Mice Neuropharmacology. Jun, 2011 | Pubmed ID: 20869373 White Matter Neuron Alterations in Schizophrenia and Related Disorders International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. May, 2011 | Pubmed ID: 20691252 Epigenetics of Schizophrenia Current Topics in Behavioral Neurosciences. 2010 | Pubmed ID: 21312415 The C-terminal TDP-43 Fragments Have a High Aggregation Propensity and Harm Neurons by a Dominant-negative Mechanism PloS One. 2010 | Pubmed ID: 21209826 Keep the 'phospho' on MAPK, Be Happy Nature Medicine. Nov, 2010 | Pubmed ID: 21052065 Gender-Specific Reduction of Estrogen-Sensitive Small RNA, MiR-30b, in Subjects With Schizophrenia Schizophrenia Bulletin. Aug, 2010 | Pubmed ID: 20732949 RPP25 is Developmentally Regulated in Prefrontal Cortex and Expressed at Decreased Levels in Autism Spectrum Disorder Autism Research : Official Journal of the International Society for Autism Research. Aug, 2010 | Pubmed ID: 20632321 Chromatin Protein L3MBTL1 is Dispensable for Development and Tumor Suppression in Mice The Journal of Biological Chemistry. Sep, 2010 | Pubmed ID: 20592034 Setdb1 Histone Methyltransferase Regulates Mood-related Behaviors and Expression of the NMDA Receptor Subunit NR2B The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2010 | Pubmed ID: 20505083 A Simple Method for Improving the Specificity of Anti-methyl Histone Antibodies Epigenetics : Official Journal of the DNA Methylation Society. Jul, 2010 | Pubmed ID: 20458167 Developmental Regulation and Individual Differences of Neuronal H3K4me3 Epigenomes in the Prefrontal Cortex Proceedings of the National Academy of Sciences of the United States of America. May, 2010 | Pubmed ID: 20421462 RAAV9--a Human-derived Adeno-associated Virus Vector for Efficient Transgene Expression in Mouse Cingulate Cortex Cold Spring Harbor Protocols. Apr, 2010 | Pubmed ID: 20360371 The Molecular Pathology of Schizophrenia--focus on Histone and DNA Modifications Brain Research Bulletin. Sep, 2010 | Pubmed ID: 19729053 Cocaine-induced Metabolic Activation in Cortico-limbic Circuitry is Increased After Exposure to the Histone Deacetylase Inhibitor, Sodium Butyrate Neuroscience Letters. Nov, 2009 | Pubmed ID: 19638299 Cingulate White Matter Neurons in Schizophrenia and Bipolar Disorder Biological Psychiatry. Sep, 2009 | Pubmed ID: 19559403 Molecular Determinants of Dysregulated GABAergic Gene Expression in the Prefrontal Cortex of Subjects with Schizophrenia Biological Psychiatry. Jun, 2009 | Pubmed ID: 19121517 Epigenetic Regulation in Human Brain-focus on Histone Lysine Methylation Biological Psychiatry. Feb, 2009 | Pubmed ID: 18814864 Restoring GABAergic Signaling and Neuronal Synchrony in Schizophrenia The American Journal of Psychiatry. Dec, 2008 | Pubmed ID: 19047328 Epigenetics in the Nervous System The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008 | Pubmed ID: 19005036 Approaching the Molecular Pathology of Suicide Biological Psychiatry. Oct, 2008 | Pubmed ID: 18926170 A Set of Differentially Expressed MiRNAs, Including MiR-30a-5p, Act As Post-transcriptional Inhibitors of BDNF in Prefrontal Cortex Human Molecular Genetics. Oct, 2008 | Pubmed ID: 18632683 Isolation of Neuronal Chromatin from Brain Tissue BMC Neuroscience. 2008 | Pubmed ID: 18442397 DNA Methylation Changes in Schizophrenia and Bipolar Disorder Epigenetics : Official Journal of the DNA Methylation Society. Mar-Apr, 2008 | Pubmed ID: 18398310 Drug-induced Activation of Dopamine D(1) Receptor Signaling and Inhibition of Class I/II Histone Deacetylase Induce Chromatin Remodeling in Reward Circuitry and Modulate Cocaine-related Behaviors Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Nov, 2008 | Pubmed ID: 18288092 Prefrontal Dysfunction in Schizophrenia Involves Mixed-lineage Leukemia 1-regulated Histone Methylation at GABAergic Gene Promoters The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2007 | Pubmed ID: 17942719 DNA Methylation in the Human Cerebral Cortex is Dynamically Regulated Throughout the Life Span and Involves Differentiated Neurons PloS One. 2007 | Pubmed ID: 17878930 GAD1 MRNA Expression and DNA Methylation in Prefrontal Cortex of Subjects with Schizophrenia PloS One. 2007 | Pubmed ID: 17726539 Antidepressant-like Effects of the Histone Deacetylase Inhibitor, Sodium Butyrate, in the Mouse Biological Psychiatry. Jul, 2007 | Pubmed ID: 16945350 The Molecular Pathology of Rett Syndrome: Synopsis and Update Neuromolecular Medicine. 2006 | Pubmed ID: 17028371 Molecular and Cellular Mechanisms of Altered GAD1/GAD67 Expression in Schizophrenia and Related Disorders Brain Research Reviews. Sep, 2006 | Pubmed ID: 16759710 NT-3 Facilitates Hippocampal Plasticity and Learning and Memory by Regulating Neurogenesis Learning & Memory (Cold Spring Harbor, N.Y.). May-Jun, 2006 | Pubmed ID: 16705139 Chromatin Immunoprecipitation in Postmortem Brain Journal of Neuroscience Methods. Sep, 2006 | Pubmed ID: 16574239 Severe Deficits in 5-HT2A -mediated Neurotransmission in BDNF Conditional Mutant Mice Journal of Neurobiology. Mar, 2006 | Pubmed ID: 16408297 Chromatin Alterations Associated with Down-regulated Metabolic Gene Expression in the Prefrontal Cortex of Subjects with Schizophrenia Archives of General Psychiatry. Aug, 2005 | Pubmed ID: 16061760 Histone Methylation at Gene Promoters is Associated with Developmental Regulation and Region-specific Expression of Ionotropic and Metabotropic Glutamate Receptors in Human Brain Journal of Neurochemistry. Jul, 2005 | Pubmed ID: 15998284 Dopamine D2-like Antagonists Induce Chromatin Remodeling in Striatal Neurons Through Cyclic AMP-protein Kinase A and NMDA Receptor Signaling Journal of Neurochemistry. Sep, 2004 | Pubmed ID: 15312167 The Neurobiology of Rett Syndrome The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Feb, 2003 | Pubmed ID: 12580340 Clinical Experts on Rett Disorder Pediatric Rehabilitation. Apr-Jun, 2002 | Pubmed ID: 12596822 Transcriptional Profiling of a Mouse Model for Rett Syndrome Reveals Subtle Transcriptional Changes in the Brain Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002 | Pubmed ID: 12432090 Diseases of the Mind and Brain: Rett's Syndrome, Part II The American Journal of Psychiatry. Aug, 2002 | Pubmed ID: 12153818 Evidence for Decreased DARPP-32 in the Prefrontal Cortex of Patients with Schizophrenia Archives of General Psychiatry. Aug, 2002 | Pubmed ID: 12150646 Diseases of the Mind and Brain: Rett's Syndrome The American Journal of Psychiatry. Jul, 2002 | Pubmed ID: 12091185 Brain-derived Neurotrophic Factor is Essential for Opiate-induced Plasticity of Noradrenergic Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002 | Pubmed ID: 12019333 Neurotrophin-3 Promotes Cell Death Induced in Cerebral Ischemia, Oxygen-glucose Deprivation, and Oxidative Stress: Possible Involvement of Oxygen Free Radicals Neurobiology of Disease. Feb, 2002 | Pubmed ID: 11848682 Isolation of Adult Human Astrocyte Populations from Fresh-Frozen Cortex Using Fluorescence-Activated Nuclei Sorting Zarmeen Mussa1,2, Jessica Tome-Garcia1,2, Yan Jiang3, Schahram Akbarian2,4, Nadejda M. Tsankova1,2 1Department of Pathology, Icahn School of Medicine at Mount Sinai, 2Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 3Institutes of Brian Science, Fudan University, 4Department of Psychiatry, Icahn School of Medicine at Mount Sinai JoVE 62405 Neuroscience Neuronal Nuclei Isolation from Human Postmortem Brain Tissue Anouch Matevossian1, Schahram Akbarian1 1Psychiatry, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School JoVE 914 Biology A Chromatin Assay for Human Brain Tissue Anouch Matevossian1, Schahram Akbarian1 1Psychiatry, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School JoVE 717 Biology
Isolation of Adult Human Astrocyte Populations from Fresh-Frozen Cortex Using Fluorescence-Activated Nuclei Sorting Zarmeen Mussa1,2, Jessica Tome-Garcia1,2, Yan Jiang3, Schahram Akbarian2,4, Nadejda M. Tsankova1,2 1Department of Pathology, Icahn School of Medicine at Mount Sinai, 2Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 3Institutes of Brian Science, Fudan University, 4Department of Psychiatry, Icahn School of Medicine at Mount Sinai JoVE 62405 Neuroscience
Neuronal Nuclei Isolation from Human Postmortem Brain Tissue Anouch Matevossian1, Schahram Akbarian1 1Psychiatry, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School JoVE 914 Biology
A Chromatin Assay for Human Brain Tissue Anouch Matevossian1, Schahram Akbarian1 1Psychiatry, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School JoVE 717 Biology
