Sean M. Wu Stanford Cardiovascular Institute Stanford University School of Medicine Biography Publications Institution JoVE Articles Sean M. Wu has not added a biography. If you are Sean M. Wu and would like to personalize this page please email our Author Liaison for assistance. Publications Single Cell Analysis of Endothelial Cells Identified Organ-Specific Molecular Signatures and Heart-Specific Cell Populations and Molecular Features Frontiers in Cardiovascular Medicine. 2019 | Pubmed ID: 31850371 Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function Stem Cell Reports. 12, 2019 | Pubmed ID: 31708475 Single-Cell Delineation of Who's on First and Second Heart Fields During Development Circulation Research. Aug, 2019 | Pubmed ID: 31518166 Bioprinting Approaches to Engineering Vascularized 3D Cardiac Tissues Current Cardiology Reports. 07, 2019 | Pubmed ID: 31352612 Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution Circulation Research. Aug, 2019 | Pubmed ID: 31284824 Single Cell Expression Analysis Reveals Anatomical and Cell Cycle-dependent Transcriptional Shifts During Heart Development Development (Cambridge, England). Jun, 2019 | Pubmed ID: 31142541 Prometheus Unbound in Ya(p) Heart Developmental Cell. 03, 2019 | Pubmed ID: 30913402 Big Bottlenecks in Cardiovascular Tissue Engineering Communications Biology. 2018 | Pubmed ID: 30480100 Single-cell Transcriptomics of 20 Mouse Organs Creates a Tabula Muris Nature. 10, 2018 | Pubmed ID: 30283141 Modelling Inherited Cardiac Disease Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes: Progress, Pitfalls, and Potential Cardiovascular Research. 12, 2018 | Pubmed ID: 30169602 Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells Circulation Research. Aug, 2018 | Pubmed ID: 29986945 Reassessment of C-Kit in Cardiac Cells: A Complex Interplay Between Expression, Fate, and Function Circulation Research. 06, 2018 | Pubmed ID: 29929968 Stage-specific Effects of Bioactive Lipids on Human IPSC Cardiac Differentiation and Cardiomyocyte Proliferation Scientific Reports. 04, 2018 | Pubmed ID: 29700394 Fates Aligned: Origins and Mechanisms of Ventricular Conduction System and Ventricular Wall Development Pediatric Cardiology. Aug, 2018 | Pubmed ID: 29594502 Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart Scientific Reports. 10, 2017 | Pubmed ID: 28974782 In Vivo Rescue of the Hematopoietic Niche By Pluripotent Stem Cell Complementation of Defective Osteoblast Compartments Stem Cells (Dayton, Ohio). 10, 2017 | Pubmed ID: 28741855 Identification of a Hybrid Myocardial Zone in the Mammalian Heart After Birth Nature Communications. Jul, 2017 | Pubmed ID: 28729659 YY1 Expression Is Sufficient for the Maintenance of Cardiac Progenitor Cell State Stem Cells (Dayton, Ohio). 08, 2017 | Pubmed ID: 28580685 Contractile Force Generation by 3D HiPSC-derived Cardiac Tissues is Enhanced by Rapid Establishment of Cellular Interconnection in Matrix with Muscle-mimicking Stiffness Biomaterials. 07, 2017 | Pubmed ID: 28384492 Bioacoustic-enabled Patterning of Human IPSC-derived Cardiomyocytes into 3D Cardiac Tissue Biomaterials. 07, 2017 | Pubmed ID: 28376365 Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons Scientific Reports. 03, 2017 | Pubmed ID: 28327614 Untangling the Biology of Genetic Cardiomyopathies with Pluripotent Stem Cell Disease Models Current Cardiology Reports. 04, 2017 | Pubmed ID: 28315121 Cardiac Regeneration: Lessons From Development Circulation Research. Mar, 2017 | Pubmed ID: 28302741 Mammalian Heart Regeneration: The Race to the Finish Line Circulation Research. 02, 2017 | Pubmed ID: 28209796 High-throughput Screening of Tyrosine Kinase Inhibitor Cardiotoxicity with Human Induced Pluripotent Stem Cells Science Translational Medicine. 02, 2017 | Pubmed ID: 28202772 Integrative Analysis of PRKAG2 Cardiomyopathy IPS and Microtissue Models Identifies AMPK As a Regulator of Metabolism, Survival, and Fibrosis Cell Reports. 12, 2016 | Pubmed ID: 28009297 Transcriptomic Profiling Maps Anatomically Patterned Subpopulations Among Single Embryonic Cardiac Cells Developmental Cell. 11, 2016 | Pubmed ID: 27840109 Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos Cell Stem Cell. 11, 2016 | Pubmed ID: 27814480 IPSC-derived Cardiomyocytes Reveal Abnormal TGF-β Signalling in Left Ventricular Non-compaction Cardiomyopathy Nature Cell Biology. 10, 2016 | Pubmed ID: 27642787 Distilling Complexity to Advance Cardiac Tissue Engineering Science Translational Medicine. Jun, 2016 | Pubmed ID: 27280684 Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls Circulation Research. Jun, 2016 | Pubmed ID: 27056912 Regenerative Medicine: Potential Mechanisms of Cardiac Recovery in Takotsubo Cardiomyopathy Current Treatment Options in Cardiovascular Medicine. Mar, 2016 | Pubmed ID: 26874708 Cardioprotective Actions of TGFβRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors Stem Cells (Dayton, Ohio). Feb, 2016 | Pubmed ID: 26418219 Lift NIH Restrictions on Chimera Research Science (New York, N.Y.). Nov, 2015 | Pubmed ID: 26542560 Members Only: Hypoxia-Induced Cell-Cycle Activation in Cardiomyocytes Cell Metabolism. Sep, 2015 | Pubmed ID: 26331604 Harnessing the Induction of Cardiomyocyte Proliferation for Cardiac Regenerative Medicine Current Treatment Options in Cardiovascular Medicine. Oct, 2015 | Pubmed ID: 26324824 Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes PloS One. 2015 | Pubmed ID: 26323090 Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss Circulation. Jul, 2015 | Pubmed ID: 25995316 Small RNAs Make Big Impact in Cardiac Repair Circulation Research. Jan, 2015 | Pubmed ID: 25634967 Identification of Cardiovascular Lineage Descendants at Single-cell Resolution Development (Cambridge, England). Mar, 2015 | Pubmed ID: 25633351 Molecular Regulation of Cardiomyocyte Differentiation Circulation Research. Jan, 2015 | Pubmed ID: 25593278 Pharmacological Inhibition of TGFβ Receptor Improves Nkx2.5 Cardiomyoblast-mediated Regeneration Cardiovascular Research. Jan, 2015 | Pubmed ID: 25362681 Patching Up Broken Hearts: Cardiac Cell Therapy Gets a Bioengineered Boost Cell Stem Cell. Dec, 2014 | Pubmed ID: 25479741 Myeloid Zinc Finger 1 (Mzf1) Differentially Modulates Murine Cardiogenesis by Interacting with an Nkx2.5 Cardiac Enhancer PloS One. 2014 | Pubmed ID: 25436607 Human Induced Pluripotent Stem Cell-derived Cardiomyocytes As an in Vitro Model for Coxsackievirus B3-induced Myocarditis and Antiviral Drug Screening Platform Circulation Research. Aug, 2014 | Pubmed ID: 25015077 Somatic Cell Reprogramming into Cardiovascular Lineages Journal of Cardiovascular Pharmacology and Therapeutics. Jul, 2014 | Pubmed ID: 24764131 Insulin-like Growth Factor Promotes Cardiac Lineage Induction in Vitro by Selective Expansion of Early Mesoderm Stem Cells (Dayton, Ohio). Jun, 2014 | Pubmed ID: 24496962 Induced Pluripotent Stem Cell-derived Cardiomyocytes for Cardiovascular Disease Modeling and Drug Screening Stem Cell Research & Therapy. 2013 | Pubmed ID: 24476344 Screening Drug-induced Arrhythmia [corrected] Using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes and Low-impedance Microelectrode Arrays Circulation. Sep, 2013 | Pubmed ID: 24030418 Of Fish and Men: Clonal Lineage Analysis Identifies Divergence in Myocardial Development Circulation Research. Feb, 2013 | Pubmed ID: 23410876 Autophagy--the Friendly Fire in Endothelial Cell Regeneration. Focus on "Autophagy in Endothelial Progenitor Cells is Cytoprotective in Hypoxic Conditions" American Journal of Physiology. Cell Physiology. Apr, 2013 | Pubmed ID: 23407881 Simple Lithography-Free Single Cell Micropatterning using Laser-Cut Stencils Soah Lee*1,2,3, Huaxiao Yang*1,2,3, Caressa Chen*1,2,3, Sneha Venkatraman1,2,3, Adrija Darsha1,2,3, Sean M. Wu1,2,3, Joseph C. Wu1,2,3, Timon Seeger1,2,3,4,5 1Stanford Cardiovascular Institute, Stanford University School of Medicine, 2Department of Medicine, Division of Cardiovascular Medicine, Stanford University, 3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 4Department of Medicine III, University Hospital Heidelberg, 5German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim JoVE 60888 Developmental Biology
Simple Lithography-Free Single Cell Micropatterning using Laser-Cut Stencils Soah Lee*1,2,3, Huaxiao Yang*1,2,3, Caressa Chen*1,2,3, Sneha Venkatraman1,2,3, Adrija Darsha1,2,3, Sean M. Wu1,2,3, Joseph C. Wu1,2,3, Timon Seeger1,2,3,4,5 1Stanford Cardiovascular Institute, Stanford University School of Medicine, 2Department of Medicine, Division of Cardiovascular Medicine, Stanford University, 3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 4Department of Medicine III, University Hospital Heidelberg, 5German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim JoVE 60888 Developmental Biology