Sebastian J. Maerkl

Publications

• A High-throughput Microfluidic Nanoimmunoassay for Detecting Anti-SARS-CoV-2 Antibodies in Serum or Ultralow-volume Blood Samples
  Proceedings of the National Academy of Sciences of the United States of America. 05, 2021  |   Pubmed ID: 33945500
• Steady-State Cell-Free Gene Expression with Microfluidic Chemostats
  Methods in Molecular Biology (Clifton, N.J.). 2021  |   Pubmed ID: 33405223
• A Partially Self-regenerating Synthetic Cell
  Nature Communications. 12, 2020  |   Pubmed ID: 33311509
• Bottom-Up Construction of Complex Biomolecular Systems With Cell-Free Synthetic Biology
  Frontiers in Bioengineering and Biotechnology. 2020  |   Pubmed ID: 32266240
• Microfluidic Systems for Cancer Diagnostics
  Current Opinion in Biotechnology. 10, 2020  |   Pubmed ID: 31891869
• Cascaded Amplifying Circuits Enable Ultrasensitive Cellular Sensors for Toxic Metals
  Nature Chemical Biology. 05, 2019  |   Pubmed ID: 30911179
• Cell-free Gene-regulatory Network Engineering with Synthetic Transcription Factors
  Proceedings of the National Academy of Sciences of the United States of America. 03, 2019  |   Pubmed ID: 30850530
• A Simple, Robust, and Low-Cost Method To Produce the PURE Cell-Free System
  ACS Synthetic Biology. 02, 2019  |   Pubmed ID: 30632751
• Microfluidic Transfection for High-Throughput Mammalian Protein Expression
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 30242688
• Microfluidic Device for Real-time Formulation of Reagents and Their Subsequent Encapsulation into Double Emulsions
  Scientific Reports. 05, 2018  |   Pubmed ID: 29802303
• Microfluidic Module for Real-Time Generation of Complex Multimolecule Temporal Concentration Profiles
  Analytical Chemistry. 01, 2018  |   Pubmed ID: 29183126
• A Microfluidic Biodisplay
  ACS Synthetic Biology. 11, 2017  |   Pubmed ID: 28771313
• GreA and GreB Enhance Expression of Escherichia Coli RNA Polymerase Promoters in a Reconstituted Transcription-Translation System
  ACS Synthetic Biology. 09, 2016  |   Pubmed ID: 27186988
• A Digital-Analog Microfluidic Platform for Patient-Centric Multiplexed Biomarker Diagnostics of Ultralow Volume Samples
  ACS Nano. Jan, 2016  |   Pubmed ID: 26741022
• Integrating Gene Synthesis and Microfluidic Protein Analysis for Rapid Protein Engineering
  Nucleic Acids Research. Apr, 2016  |   Pubmed ID: 26704969
• Mechanically Induced Trapping of Molecular Interactions and Its Applications
  Journal of Laboratory Automation. Jun, 2016  |   Pubmed ID: 25805850
• Rapid Cell-free Forward Engineering of Novel Genetic Ring Oscillators
  ELife. Oct, 2015  |   Pubmed ID: 26430766
• A Microfluidic Platform for High-throughput Multiplexed Protein Quantitation
  PloS One. 2015  |   Pubmed ID: 25680117
• Two Distinct Promoter Architectures Centered on Dynamic Nucleosomes Control Ribosomal Protein Gene Transcription
  Genes & Development. Aug, 2014  |   Pubmed ID: 25085421
• Long-term Single Cell Analysis of S. Pombe on a Microfluidic Microchemostat Array
  PloS One. 2014  |   Pubmed ID: 24710337
• A 1024-sample Serum Analyzer Chip for Cancer Diagnostics
  Lab on a Chip. Aug, 2014  |   Pubmed ID: 24345965
• Implementation of Cell-free Biological Networks at Steady State
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013  |   Pubmed ID: 24043836
• A Chemostat Array Enables the Spatio-temporal Analysis of the Yeast Proteome
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2013  |   Pubmed ID: 24019481
• Mapping the Fine Structure of a Eukaryotic Promoter Input-output Function
  Nature Genetics. Oct, 2013  |   Pubmed ID: 23955598
• Live Mammalian Cell Arrays
  Nature Methods. Jun, 2013  |   Pubmed ID: 23644546
• A High-throughput Nanoimmunoassay Chip Applied to Large-scale Vaccine Adjuvant Screening
  Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2013  |   Pubmed ID: 23443913
• ISLIM: a Comprehensive Approach to Mapping and Characterizing Gene Regulatory Networks
  Nucleic Acids Research. Feb, 2013  |   Pubmed ID: 23258699
• Multiplexed Surface Micropatterning of Proteins with a Pressure-modulated Microfluidic Button-membrane
  Chemical Communications (Cambridge, England). Feb, 2013  |   Pubmed ID: 23183795
• Rapid Synthesis of Defined Eukaryotic Promoter Libraries
  ACS Synthetic Biology. Oct, 2012  |   Pubmed ID: 23656186
• Massively Parallel Measurements of Molecular Interaction Kinetics on a Microfluidic Platform
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012  |   Pubmed ID: 23012409
• Probing the Informational and Regulatory Plasticity of a Transcription Factor DNA-binding Domain
  PLoS Genetics. 2012  |   Pubmed ID: 22496663
• MITOMI: a Microfluidic Platform for in Vitro Characterization of Transcription Factor-DNA Interaction
  Methods in Molecular Biology (Clifton, N.J.). 2012  |   Pubmed ID: 21938622
• Does Positive Selection Drive Transcription Factor Binding Site Turnover? A Test with Drosophila Cis-regulatory Modules
  PLoS Genetics. Apr, 2011  |   Pubmed ID: 21572512
• A Software-programmable Microfluidic Device for Automated Biology
  Lab on a Chip. May, 2011  |   Pubmed ID: 21416077
• Next Generation Microfluidic Platforms for High-throughput Protein Biochemistry
  Current Opinion in Biotechnology. Feb, 2011  |   Pubmed ID: 20832278
• Experimental Strategies for Studying Transcription Factor-DNA Binding Specificities
  Briefings in Functional Genomics. Dec, 2010  |   Pubmed ID: 20864494
• Integration Column: Microfluidic High-throughput Screening
  Integrative Biology : Quantitative Biosciences from Nano to Macro. Jan, 2009  |   Pubmed ID: 20023788