Seth Blackshaw Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Seth Blackshaw has not added a biography. If you are Seth Blackshaw and would like to personalize this page please email our Author Liaison for assistance. Publications Midkine is Neuroprotective and Influences Glial Reactivity and the Formation of Müller Glia-derived Progenitor Cells in Chick and Mouse Retinas Glia. Feb, 2021 | Pubmed ID: 33569849 Temperature and Species-dependent Regulation of Browning in Retrobulbar Fat Scientific Reports. Feb, 2021 | Pubmed ID: 33542375 Turning Lead into Gold: Reprogramming Retinal Cells to Cure Blindness The Journal of Clinical Investigation. Feb, 2021 | Pubmed ID: 33529169 Gene Regulatory Networks Controlling Differentiation, Survival, and Diversification of Hypothalamic Lhx6-expressing GABAergic Neurons Communications Biology. Jan, 2021 | Pubmed ID: 33479483 Gene Regulatory Networks Controlling Vertebrate Retinal Regeneration Science (New York, N.Y.). 11, 2020 | Pubmed ID: 33004674 Zeb2 Regulates the Balance Between Retinal Interneurons and Müller Glia by Inhibition of BMP-Smad Signaling Developmental Biology. 12, 2020 | Pubmed ID: 32950463 The Cellular and Molecular Landscape of Hypothalamic Patterning and Differentiation from Embryonic to Late Postnatal Development Nature Communications. 08, 2020 | Pubmed ID: 32868762 Epigenetic Hallmarks of Age-related Macular Degeneration Are Recapitulated in a Photosensitive Mouse Model Human Molecular Genetics. Aug, 2020 | Pubmed ID: 32691052 Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development Developmental Cell. 05, 2020 | Pubmed ID: 32386599 NF-κB Signaling Regulates the Formation of Proliferating Müller Glia-derived Progenitor Cells in the Avian Retina Development (Cambridge, England). 05, 2020 | Pubmed ID: 32291273 Tanycyte Ablation in the Arcuate Nucleus and Median Eminence Increases Obesity Susceptibility by Increasing Body Fat Content in Male Mice Glia. Oct, 2020 | Pubmed ID: 32173924 ASCOT Identifies Key Regulators of Neuronal Subtype-specific Splicing Nature Communications. 01, 2020 | Pubmed ID: 31919425 Clarin-1 Expression in Adult Mouse and Human Retina Highlights a Role of Müller Glia in Usher Syndrome The Journal of Pathology. 02, 2020 | Pubmed ID: 31625146 Photic Generation of 11--retinal in Bovine Retinal Pigment Epithelium The Journal of Biological Chemistry. 12, 2019 | Pubmed ID: 31694912 PanoView: An Iterative Clustering Method for Single-cell RNA Sequencing Data PLoS Computational Biology. 08, 2019 | Pubmed ID: 31469823 Global Analysis of Intercellular Homeodomain Protein Transfer Cell Reports. 07, 2019 | Pubmed ID: 31315049 Matrix-metalloproteinase Expression and Gelatinase Activity in the Avian Retina and Their Influence on Müller Glia Proliferation Experimental Neurology. 10, 2019 | Pubmed ID: 31251936 Reactive Microglia and IL1β/IL-1R1-signaling Mediate Neuroprotection in Excitotoxin-damaged Mouse Retina Journal of Neuroinflammation. Jun, 2019 | Pubmed ID: 31170999 Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors As Regulating Mitotic Exit and Late-Born Cell Specification Neuron. 06, 2019 | Pubmed ID: 31128945 The Selective Estrogen Receptor Modulator Raloxifene Mitigates the Effect of All--retinal Toxicity in Photoreceptor Degeneration The Journal of Biological Chemistry. 06, 2019 | Pubmed ID: 31073029 Epigenomic Profiling of Retinal Progenitors Reveals LHX2 is Required for Developmental Regulation of Open Chromatin Communications Biology. 2019 | Pubmed ID: 31044167 Conditional Deletion of Des1 in the Mouse Retina Does Not Impair the Visual Cycle in Cones FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 04, 2019 | Pubmed ID: 30645148 Disruption of Stromal Hedgehog Signaling Initiates RNF5-mediated Proteasomal Degradation of PTEN and Accelerates Pancreatic Tumor Growth Life Science Alliance. Oct, 2018 | Pubmed ID: 30456390 Canonical Wnt Signaling Regulates Patterning, Differentiation and Nucleogenesis in Mouse Hypothalamus and Prethalamus Developmental Biology. 10, 2018 | Pubmed ID: 30063881 Asymmetric Vasopressin Signaling Spatially Organizes the Master Circadian Clock The Journal of Comparative Neurology. 09, 2018 | Pubmed ID: 29931690 Antibody Specificity Profiling Using Protein Microarrays Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29714021 Foxd1 is Required for Terminal Differentiation of Anterior Hypothalamic Neuronal Subtypes Developmental Biology. 07, 2018 | Pubmed ID: 29679559 Ldb1- and Rnf12-dependent Regulation of Lhx2 Controls the Relative Balance Between Neurogenesis and Gliogenesis in the Retina Development (Cambridge, England). 04, 2018 | Pubmed ID: 29650591 A Toolbox of Immunoprecipitation-grade Monoclonal Antibodies to Human Transcription Factors Nature Methods. 05, 2018 | Pubmed ID: 29638227 ATAC-Seq Analysis Reveals a Widespread Decrease of Chromatin Accessibility in Age-related Macular Degeneration Nature Communications. 04, 2018 | Pubmed ID: 29636475 Regulation and Function of Neurogenesis in the Adult Mammalian Hypothalamus Progress in Neurobiology. 11, 2018 | Pubmed ID: 29631023 Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk Between SUMOylation and Phosphorylation Promotes Cell Migration Molecular & Cellular Proteomics : MCP. 05, 2018 | Pubmed ID: 29438996 In Vivo Electroporation of Developing Mouse Retina Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29188509 Pax6 is Essential for the Generation of Late-born Retinal Neurons and for Inhibition of Photoreceptor-fate During Late Stages of Retinogenesis Developmental Biology. 12, 2017 | Pubmed ID: 28993200 Lhx6-positive GABA-releasing Neurons of the Zona Incerta Promote Sleep Nature. 08, 2017 | Pubmed ID: 28847002 Understanding the Role of LncRNAs in Nervous System Development Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 28815543 Assessing the Model Transferability for Prediction of Transcription Factor Binding Sites Based on Chromatin Accessibility BMC Bioinformatics. Jul, 2017 | Pubmed ID: 28750606 Global Analysis of SUMO-Binding Proteins Identifies SUMOylation As a Key Regulator of the INO80 Chromatin Remodeling Complex Molecular & Cellular Proteomics : MCP. 05, 2017 | Pubmed ID: 28254775 The Long Non-coding RNA NEAT1 is Responsive to Neuronal Activity and is Associated with Hyperexcitability States Scientific Reports. 01, 2017 | Pubmed ID: 28054653 An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks Current Biology : CB. Jan, 2017 | Pubmed ID: 28017605 A Nuclease That Mediates Cell Death Induced by DNA Damage and Poly(ADP-ribose) Polymerase-1 Science (New York, N.Y.). 10, 2016 | Pubmed ID: 27846469 The Stage-dependent Roles of Ldb1 and Functional Redundancy with Ldb2 in Mammalian Retinogenesis Development (Cambridge, England). 11, 2016 | Pubmed ID: 27697904 The NIH Protein Capture Reagents Program (PCRP): a Standardized Protein Affinity Reagent Toolbox Nature Methods. 09, 2016 | Pubmed ID: 27684578 Control of Lens Development by Lhx2-regulated Neuroretinal FGFs Development (Cambridge, England). 11, 2016 | Pubmed ID: 27633990 Multiple Intrinsic Factors Act in Concert with Lhx2 to Direct Retinal Gliogenesis Scientific Reports. 09, 2016 | Pubmed ID: 27605455 Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier Genetics. 06, 2016 | Pubmed ID: 27029737 The Nutrient Sensor OGT in PVN Neurons Regulates Feeding Science (New York, N.Y.). Mar, 2016 | Pubmed ID: 26989246 Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2016 | Pubmed ID: 26911688 EphA4 is Involved in Sleep Regulation but Not in the Electrophysiological Response to Sleep Deprivation Sleep. Mar, 2016 | Pubmed ID: 26612390 Constructing the Suprachiasmatic Nucleus: a Watchmaker's Perspective on the Central Clockworks Frontiers in Systems Neuroscience. 2015 | Pubmed ID: 26005407 Identification of SUMO E3 Ligase-specific Substrates Using the HuProt Human Proteome Microarray Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25820740 Patterning, Specification, and Differentiation in the Developing Hypothalamus Wiley Interdisciplinary Reviews. Developmental Biology. Sep-Oct, 2015 | Pubmed ID: 25820448 A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors Neuron. Feb, 2015 | Pubmed ID: 25654255 The LIM Homeodomain Factor Lhx2 is Required for Hypothalamic Tanycyte Specification and Differentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2014 | Pubmed ID: 25505333 Notch3 Interactome Analysis Identified WWP2 As a Negative Regulator of Notch3 Signaling in Ovarian Cancer PLoS Genetics. Oct, 2014 | Pubmed ID: 25356737 Serine Racemase Regulated by Binding to Stargazin and PSD-95: Potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (NMDA-AMPA) Glutamate Neurotransmission Cross-talk The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25164819 Characterization of the SUMO-binding Activity of the Myeloproliferative and Mental Retardation (MYM)-type Zinc Fingers in ZNF261 and ZNF198 PloS One. 2014 | Pubmed ID: 25133527 Dietary and Sex-specific Factors Regulate Hypothalamic Neurogenesis in Young Adult Mice Frontiers in Neuroscience. 2014 | Pubmed ID: 24982613 Long Non-coding RNA-dependent Transcriptional Regulation in Neuronal Development and Disease Frontiers in Genetics. 2014 | Pubmed ID: 24936207 Lhx1 Controls Terminal Differentiation and Circadian Function of the Suprachiasmatic Nucleus Cell Reports. May, 2014 | Pubmed ID: 24767996 Rax-CreERT2 Knock-in Mice: a Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus PloS One. 2014 | Pubmed ID: 24699247 Feed Your Head: Neurodevelopmental Control of Feeding and Metabolism Annual Review of Physiology. 2014 | Pubmed ID: 24274739 Stage-specific Inhibition of TrkB Activity Leads to Long-lasting and Sexually Dimorphic Effects on Body Weight and Hypothalamic Gene Expression PloS One. 2013 | Pubmed ID: 24312242 RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention Neuron. Oct, 2013 | Pubmed ID: 24139042 Protein Microarray Characterization of the S-nitrosoproteome Molecular & Cellular Proteomics : MCP. Oct, 2013 | Pubmed ID: 24105792 Estrogen-related Receptor Beta Deficiency Alters Body Composition and Response to Restraint Stress BMC Physiology. Sep, 2013 | Pubmed ID: 24053666 Rax Regulates Hypothalamic Tanycyte Differentiation and Barrier Function in Mice The Journal of Comparative Neurology. Aug, 2013 | Pubmed ID: 23939786 Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity Molecular & Cellular Proteomics : MCP. Oct, 2013 | Pubmed ID: 23824909 LHX2 is Necessary for the Maintenance of Optic Identity and for the Progression of Optic Morphogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2013 | Pubmed ID: 23595746 Identification of Hypothalamic Neuron-derived Neurotrophic Factor As a Novel Factor Modulating Appetite American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jun, 2013 | Pubmed ID: 23576617 Construction of Human Activity-based Phosphorylation Networks Molecular Systems Biology. 2013 | Pubmed ID: 23549483 Estrogen-related Receptor β Deletion Modulates Whole-body Energy Balance Via Estrogen-related Receptor γ and Attenuates Neuropeptide Y Gene Expression The European Journal of Neuroscience. Apr, 2013 | Pubmed ID: 23360481 High-throughput RNA in Situ Hybridization in Mouse Retina Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23150371 Functional Implications of Hypothalamic Neurogenesis in the Adult Mammalian Brain International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Dec, 2012 | Pubmed ID: 22867732 WITHDRAWN: Functional Implications of Hypothalamic Neurogenesis in the Adult Mammalian Brain International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Jul, 2012 | Pubmed ID: 22814121 Identification of New Autoantigens for Primary Biliary Cirrhosis Using Human Proteome Microarrays Molecular & Cellular Proteomics : MCP. Sep, 2012 | Pubmed ID: 22647870 Tanycytes of the Hypothalamic Median Eminence Form a Diet-responsive Neurogenic Niche Nature Neuroscience. May, 2012 | Pubmed ID: 22446882 Botch Promotes Neurogenesis by Antagonizing Notch Developmental Cell. Apr, 2012 | Pubmed ID: 22445366 Injury-independent Induction of Reactive Gliosis in Retina by Loss of Function of the LIM Homeodomain Transcription Factor Lhx2 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22393024 Identification Rapide Des Anticorps Monoclonaux Monospécifiques L'aide D'un Protéome Humain Microarray Molecular & Cellular Proteomics : MCP. Feb, 2012 | Pubmed ID: 22307071 Règlement De La CK2 Par Phosphorylation Et O-GlcNAcylation Révélé Par Hémisynthèse Nature Chemical Biology. 2012 | Pubmed ID: 22267120 Une Levure Hybrides Dosages Pour Gene-centrée De Cartographie Génique Human Network De La Réglementation Nature Methods. Dec, 2011 | Pubmed ID: 22037702 Le Long ARN Non Codant Six3OS Acts De Trans Pour Réglementer Le Développement De La Rétine Par L'activité SIX3 Modulant Neural Development. 2011 | Pubmed ID: 21936910 Nous Contiens Des Multitudes: Le Visage Protéiforme De Rétinoblastome Cancer Cell. Aug, 2011 | Pubmed ID: 21840479 La Famille Sall3 Spalt Transcription Factor Régule Le Développement Des Photorécepteurs De La Rétine Et Du Cône Interneurones Horizontales Development (Cambridge, England). Jun, 2011 | Pubmed ID: 21558380 Caractérisation Des Interactions Protéine-ADN à L'aide Des Puces à Protéines Cold Spring Harbor Protocols. May, 2011 | Pubmed ID: 21536762 Caractérisation Systématique Des Interactions Protéine-ADN Cellular and Molecular Life Sciences : CMLS. May, 2011 | Pubmed ID: 21207099 Spécifique à La Région L'expression Génique Dans Thalamus Souris Postnatale Précoce The Journal of Comparative Neurology. Feb, 2011 | Pubmed ID: 21192083 Dynamique Spatio-temporelle Dans L'expression Génique Thalamus Embryonnaire De La Souris The Journal of Comparative Neurology. Feb, 2011 | Pubmed ID: 21192082 Fonctionnelle La Technologie Des Microréseaux De Protéines Wiley Interdisciplinary Reviews. Systems Biology and Medicine. May-Jun, 2011 | Pubmed ID: 20872749 Voies Moléculaires Qui Régissent Le Développement Des Thalamus Et L'hypothalamus: à Partir De La Spécification à La Formation Des Circuits Neuronaux The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2010 | Pubmed ID: 21068293 Pias3-dépendante SUMOylation Contrôle Des Mammifères Différenciation Photorécepteur Cône Nature Neuroscience. Sep, 2010 | Pubmed ID: 20729845 Trois Dimensions Micro-images De Tenseur De Diffusion Pour La Caractérisation Anatomique Du Cerveau De Souris Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2010 | Pubmed ID: 20577980 Le Nucléaire Orphelin Récepteurs Hormonaux ERRbeta Contrôle Rod Photorécepteur De Survie Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534447 Le Long ARN Non Codant RNCR2 Dirige La Spécification Des Cellules De Souris Rétinienne BMC Developmental Biology. 2010 | Pubmed ID: 20459797 Un Atlas Génomique De La Souris Hypothalamo Développement Nature Neuroscience. Jun, 2010 | Pubmed ID: 20436479 HPDI: Une Base De Données Expérimentales De L'homme Interactions Protéine-ADN Bioinformatics (Oxford, England). Jan, 2010 | Pubmed ID: 19900953 Vertébrés Retina Et Le Développement Hypothalamus Wiley Interdisciplinary Reviews. Systems Biology and Medicine. Nov-Dec, 2009 | Pubmed ID: 20836003 Profilage De La Protéine Humaine D'ADN Révèle Interactome ERK2 Comme Un Répresseur Transcriptionnel De La Signalisation De L'interféron Cell. Oct, 2009 | Pubmed ID: 19879846 Muscleblind-like 2: Expression Du Rythme Circadien Dans La Glande Pinéale Chez Les Mammifères Est Contrôlée Par Un Mécanisme Adrénergique-AMPc Journal of Neurochemistry. Jul, 2009 | Pubmed ID: 19457059 Une Nouvelle Signification Dans Le Message: ARN Non Codantes Et Leur Rôle Dans Le Développement Rétinien Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2009 | Pubmed ID: 19191220 Pias3-dépendante SUMOylation Diriger Rod Photorécepteur Développement Neuron. Jan, 2009 | Pubmed ID: 19186166 D-aspartate Et D-aspartate Oxydase Montrer La Localisation Sélective Et Développemental Dynamique Dans La Rétine De Souris Experimental Eye Research. Apr, 2008 | Pubmed ID: 18314103 Analyse Sérielle D'expression Génique (SAGE): Méthode Expérimentale Et Analyse Des Données Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [et Al.]. Apr, 2007 | Pubmed ID: 18428405 Analyse Sérielle D'expression Génique (SAGE): Méthode Expérimentale Et Analyse Des Données Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [et Al.]. Oct, 2007 | Pubmed ID: 18265400 Modifications Du Comportement Chez Les Souris Mâles Dépourvues Du Gène Pour D-aspartate Oxydase Behavioural Brain Research. Aug, 2006 | Pubmed ID: 16725213 D-aspartate Et Régule La Formation Melanocortin Fonction: Modifications Du Comportement En D-aspartate Oxydase Chez Les Souris Déficientes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16525061 Méthionine Adénosyltransférase: Adrénergique-AMPc Mécanisme Régule Un Rythme Quotidien Dans Expression Pinéale The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15504733 Analyse De La Concentration Des Données SAGE En Utilisant Une Approche De Poisson Genome Biology. 2004 | Pubmed ID: 15239836 Analyse Génomique De Développement De La Souris La Rétine PLoS Biology. Sep, 2004 | Pubmed ID: 15226823 MicroSAGE Est Très Représentatif Et Reproductible, Mais Constate De Grandes Différences Dans L'expression Génique Chez Les échantillons Obtenus à Partir Des Tissus Similaires Genome Biology. 2003 | Pubmed ID: 12620102 Des Cellules Souches Qui Connaissent Leur Place Nature Neuroscience. Dec, 2002 | Pubmed ID: 12447376 Le AIPL1 Cécité Héréditaire D'une Protéine Associée Interagit Avec La Protéine Régulateur Cell Cycle NUB1 Human Molecular Genetics. Oct, 2002 | Pubmed ID: 12374762 Des Mutations Dans Le Inosine Monophosphate Déshydrogénase 1 Gene (IMPDH1) Parce Que Le Formulaire De RP10 Rétinite Pigmentaire Autosomique Dominante Human Molecular Genetics. Mar, 2002 | Pubmed ID: 11875050 L'application De Technologies Génomiques Au Développement Neuronal Current Opinion in Neurobiology. Feb, 2002 | Pubmed ID: 11861173 Profil Des Gènes Exprimés Dans La Rétine Humaine Périphérique, Macula, Et L'épithélium Pigmentaire Rétinien Déterminé Par Une Analyse Sérielle D'expression Génique (SAGE) Proceedings of the National Academy of Sciences of the United States of America. Jan, 2002 | Pubmed ID: 11756676 Poly(ADP-ribosyl)ation Basally Activated by DNA Strand Breaks Reflects Glutamate-nitric Oxide Neurotransmission Proceedings of the National Academy of Sciences of the United States of America. Feb, 2000 | Pubmed ID: 10677544 A Novel Neuron-enriched Homolog of the Erythrocyte Membrane Cytoskeletal Protein 4.1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 1999 | Pubmed ID: 10414974 Poly(ADP-ribose) Polymerase-deficient Mice Are Protected from Streptozotocin-induced Diabetes Proceedings of the National Academy of Sciences of the United States of America. Mar, 1999 | Pubmed ID: 10077636 The 13-kD FK506 Binding Protein, FKBP13, Interacts with a Novel Homologue of the Erythrocyte Membrane Cytoskeletal Protein 4.1 The Journal of Cell Biology. Apr, 1998 | Pubmed ID: 9531554 Parapinopsin, a Novel Catfish Opsin Localized to the Parapineal Organ, Defines a New Gene Family The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1997 | Pubmed ID: 9334384 Developmental Expression Pattern of Phototransduction Components in Mammalian Pineal Implies a Light-sensing Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1997 | Pubmed ID: 9334383 The Development of Excitatory Synapses in Cultured Spinal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 1997 | Pubmed ID: 9295380 Neuronal Nitric Oxide Synthase Alternatively Spliced Forms: Prominent Functional Localizations in the Brain Proceedings of the National Academy of Sciences of the United States of America. Apr, 1997 | Pubmed ID: 9096405 Analyse multiplexée de l’expression génique rétinienne et de l’accessibilité de la chromatine à l’aide de scRNA-Seq et scATAC-Seq Kurt Weir*1, Patrick Leavey*1, Clayton Santiago1, Seth Blackshaw1,2,3,4,5,6 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine JoVE 62239 Neuroscience Interrogation fonctionnelle des adultes hypothalamique neurogenèse avec Focal radiologique inhibition Daniel A. Lee1,2, Juan Salvatierra2, Esteban Velarde3, John Wong3, Eric C. Ford4, Seth Blackshaw2,5 1Division of Biology, California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 4Department of Radiation Oncology, University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine JoVE 50716 Neuroscience En électroporation in vivo de la rétine de souris en développement Jimmy de Melo1, Seth Blackshaw1,2,3,4,5 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, 2Department of Neurology, Johns Hopkins School of Medicine, 3Department of Ophthalmology, Johns Hopkins School of Medicine, 4Center for High-Throughput Biology, Johns Hopkins School of Medicine, 5Institute for Cell Engineering, Johns Hopkins School of Medicine JoVE 2847 Neuroscience
Analyse multiplexée de l’expression génique rétinienne et de l’accessibilité de la chromatine à l’aide de scRNA-Seq et scATAC-Seq Kurt Weir*1, Patrick Leavey*1, Clayton Santiago1, Seth Blackshaw1,2,3,4,5,6 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine JoVE 62239 Neuroscience
Interrogation fonctionnelle des adultes hypothalamique neurogenèse avec Focal radiologique inhibition Daniel A. Lee1,2, Juan Salvatierra2, Esteban Velarde3, John Wong3, Eric C. Ford4, Seth Blackshaw2,5 1Division of Biology, California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 4Department of Radiation Oncology, University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine JoVE 50716 Neuroscience
En électroporation in vivo de la rétine de souris en développement Jimmy de Melo1, Seth Blackshaw1,2,3,4,5 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, 2Department of Neurology, Johns Hopkins School of Medicine, 3Department of Ophthalmology, Johns Hopkins School of Medicine, 4Center for High-Throughput Biology, Johns Hopkins School of Medicine, 5Institute for Cell Engineering, Johns Hopkins School of Medicine JoVE 2847 Neuroscience