Seth Blackshaw Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Seth Blackshaw has not added a biography. If you are Seth Blackshaw and would like to personalize this page please email our Author Liaison for assistance. Publications Midkine is Neuroprotective and Influences Glial Reactivity and the Formation of Müller Glia-derived Progenitor Cells in Chick and Mouse Retinas Glia. Feb, 2021 | Pubmed ID: 33569849 Temperature and Species-dependent Regulation of Browning in Retrobulbar Fat Scientific Reports. Feb, 2021 | Pubmed ID: 33542375 Turning Lead into Gold: Reprogramming Retinal Cells to Cure Blindness The Journal of Clinical Investigation. Feb, 2021 | Pubmed ID: 33529169 Gene Regulatory Networks Controlling Differentiation, Survival, and Diversification of Hypothalamic Lhx6-expressing GABAergic Neurons Communications Biology. Jan, 2021 | Pubmed ID: 33479483 Gene Regulatory Networks Controlling Vertebrate Retinal Regeneration Science (New York, N.Y.). 11, 2020 | Pubmed ID: 33004674 Zeb2 Regulates the Balance Between Retinal Interneurons and Müller Glia by Inhibition of BMP-Smad Signaling Developmental Biology. 12, 2020 | Pubmed ID: 32950463 The Cellular and Molecular Landscape of Hypothalamic Patterning and Differentiation from Embryonic to Late Postnatal Development Nature Communications. 08, 2020 | Pubmed ID: 32868762 Epigenetic Hallmarks of Age-related Macular Degeneration Are Recapitulated in a Photosensitive Mouse Model Human Molecular Genetics. Aug, 2020 | Pubmed ID: 32691052 Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development Developmental Cell. 05, 2020 | Pubmed ID: 32386599 NF-κB Signaling Regulates the Formation of Proliferating Müller Glia-derived Progenitor Cells in the Avian Retina Development (Cambridge, England). 05, 2020 | Pubmed ID: 32291273 Tanycyte Ablation in the Arcuate Nucleus and Median Eminence Increases Obesity Susceptibility by Increasing Body Fat Content in Male Mice Glia. Oct, 2020 | Pubmed ID: 32173924 ASCOT Identifies Key Regulators of Neuronal Subtype-specific Splicing Nature Communications. 01, 2020 | Pubmed ID: 31919425 Clarin-1 Expression in Adult Mouse and Human Retina Highlights a Role of Müller Glia in Usher Syndrome The Journal of Pathology. 02, 2020 | Pubmed ID: 31625146 Photic Generation of 11--retinal in Bovine Retinal Pigment Epithelium The Journal of Biological Chemistry. 12, 2019 | Pubmed ID: 31694912 PanoView: An Iterative Clustering Method for Single-cell RNA Sequencing Data PLoS Computational Biology. 08, 2019 | Pubmed ID: 31469823 Global Analysis of Intercellular Homeodomain Protein Transfer Cell Reports. 07, 2019 | Pubmed ID: 31315049 Matrix-metalloproteinase Expression and Gelatinase Activity in the Avian Retina and Their Influence on Müller Glia Proliferation Experimental Neurology. 10, 2019 | Pubmed ID: 31251936 Reactive Microglia and IL1β/IL-1R1-signaling Mediate Neuroprotection in Excitotoxin-damaged Mouse Retina Journal of Neuroinflammation. Jun, 2019 | Pubmed ID: 31170999 Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors As Regulating Mitotic Exit and Late-Born Cell Specification Neuron. 06, 2019 | Pubmed ID: 31128945 The Selective Estrogen Receptor Modulator Raloxifene Mitigates the Effect of All--retinal Toxicity in Photoreceptor Degeneration The Journal of Biological Chemistry. 06, 2019 | Pubmed ID: 31073029 Epigenomic Profiling of Retinal Progenitors Reveals LHX2 is Required for Developmental Regulation of Open Chromatin Communications Biology. 2019 | Pubmed ID: 31044167 Conditional Deletion of Des1 in the Mouse Retina Does Not Impair the Visual Cycle in Cones FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 04, 2019 | Pubmed ID: 30645148 Disruption of Stromal Hedgehog Signaling Initiates RNF5-mediated Proteasomal Degradation of PTEN and Accelerates Pancreatic Tumor Growth Life Science Alliance. Oct, 2018 | Pubmed ID: 30456390 Canonical Wnt Signaling Regulates Patterning, Differentiation and Nucleogenesis in Mouse Hypothalamus and Prethalamus Developmental Biology. 10, 2018 | Pubmed ID: 30063881 Asymmetric Vasopressin Signaling Spatially Organizes the Master Circadian Clock The Journal of Comparative Neurology. 09, 2018 | Pubmed ID: 29931690 Antibody Specificity Profiling Using Protein Microarrays Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29714021 Foxd1 is Required for Terminal Differentiation of Anterior Hypothalamic Neuronal Subtypes Developmental Biology. 07, 2018 | Pubmed ID: 29679559 Ldb1- and Rnf12-dependent Regulation of Lhx2 Controls the Relative Balance Between Neurogenesis and Gliogenesis in the Retina Development (Cambridge, England). 04, 2018 | Pubmed ID: 29650591 A Toolbox of Immunoprecipitation-grade Monoclonal Antibodies to Human Transcription Factors Nature Methods. 05, 2018 | Pubmed ID: 29638227 ATAC-Seq Analysis Reveals a Widespread Decrease of Chromatin Accessibility in Age-related Macular Degeneration Nature Communications. 04, 2018 | Pubmed ID: 29636475 Regulation and Function of Neurogenesis in the Adult Mammalian Hypothalamus Progress in Neurobiology. 11, 2018 | Pubmed ID: 29631023 Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk Between SUMOylation and Phosphorylation Promotes Cell Migration Molecular & Cellular Proteomics : MCP. 05, 2018 | Pubmed ID: 29438996 In Vivo Electroporation of Developing Mouse Retina Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29188509 Pax6 is Essential for the Generation of Late-born Retinal Neurons and for Inhibition of Photoreceptor-fate During Late Stages of Retinogenesis Developmental Biology. 12, 2017 | Pubmed ID: 28993200 Lhx6-positive GABA-releasing Neurons of the Zona Incerta Promote Sleep Nature. 08, 2017 | Pubmed ID: 28847002 Understanding the Role of LncRNAs in Nervous System Development Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 28815543 Assessing the Model Transferability for Prediction of Transcription Factor Binding Sites Based on Chromatin Accessibility BMC Bioinformatics. Jul, 2017 | Pubmed ID: 28750606 Global Analysis of SUMO-Binding Proteins Identifies SUMOylation As a Key Regulator of the INO80 Chromatin Remodeling Complex Molecular & Cellular Proteomics : MCP. 05, 2017 | Pubmed ID: 28254775 The Long Non-coding RNA NEAT1 is Responsive to Neuronal Activity and is Associated with Hyperexcitability States Scientific Reports. 01, 2017 | Pubmed ID: 28054653 An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks Current Biology : CB. Jan, 2017 | Pubmed ID: 28017605 A Nuclease That Mediates Cell Death Induced by DNA Damage and Poly(ADP-ribose) Polymerase-1 Science (New York, N.Y.). 10, 2016 | Pubmed ID: 27846469 The Stage-dependent Roles of Ldb1 and Functional Redundancy with Ldb2 in Mammalian Retinogenesis Development (Cambridge, England). 11, 2016 | Pubmed ID: 27697904 The NIH Protein Capture Reagents Program (PCRP): a Standardized Protein Affinity Reagent Toolbox Nature Methods. 09, 2016 | Pubmed ID: 27684578 Control of Lens Development by Lhx2-regulated Neuroretinal FGFs Development (Cambridge, England). 11, 2016 | Pubmed ID: 27633990 Multiple Intrinsic Factors Act in Concert with Lhx2 to Direct Retinal Gliogenesis Scientific Reports. 09, 2016 | Pubmed ID: 27605455 Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier Genetics. 06, 2016 | Pubmed ID: 27029737 The Nutrient Sensor OGT in PVN Neurons Regulates Feeding Science (New York, N.Y.). Mar, 2016 | Pubmed ID: 26989246 Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2016 | Pubmed ID: 26911688 EphA4 is Involved in Sleep Regulation but Not in the Electrophysiological Response to Sleep Deprivation Sleep. Mar, 2016 | Pubmed ID: 26612390 Constructing the Suprachiasmatic Nucleus: a Watchmaker's Perspective on the Central Clockworks Frontiers in Systems Neuroscience. 2015 | Pubmed ID: 26005407 Identification of SUMO E3 Ligase-specific Substrates Using the HuProt Human Proteome Microarray Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25820740 Patterning, Specification, and Differentiation in the Developing Hypothalamus Wiley Interdisciplinary Reviews. Developmental Biology. Sep-Oct, 2015 | Pubmed ID: 25820448 A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors Neuron. Feb, 2015 | Pubmed ID: 25654255 The LIM Homeodomain Factor Lhx2 is Required for Hypothalamic Tanycyte Specification and Differentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2014 | Pubmed ID: 25505333 Notch3 Interactome Analysis Identified WWP2 As a Negative Regulator of Notch3 Signaling in Ovarian Cancer PLoS Genetics. Oct, 2014 | Pubmed ID: 25356737 Serine Racemase Regulated by Binding to Stargazin and PSD-95: Potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (NMDA-AMPA) Glutamate Neurotransmission Cross-talk The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25164819 Characterization of the SUMO-binding Activity of the Myeloproliferative and Mental Retardation (MYM)-type Zinc Fingers in ZNF261 and ZNF198 PloS One. 2014 | Pubmed ID: 25133527 Dietary and Sex-specific Factors Regulate Hypothalamic Neurogenesis in Young Adult Mice Frontiers in Neuroscience. 2014 | Pubmed ID: 24982613 Long Non-coding RNA-dependent Transcriptional Regulation in Neuronal Development and Disease Frontiers in Genetics. 2014 | Pubmed ID: 24936207 Lhx1 Controls Terminal Differentiation and Circadian Function of the Suprachiasmatic Nucleus Cell Reports. May, 2014 | Pubmed ID: 24767996 Rax-CreERT2 Knock-in Mice: a Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus PloS One. 2014 | Pubmed ID: 24699247 Feed Your Head: Neurodevelopmental Control of Feeding and Metabolism Annual Review of Physiology. 2014 | Pubmed ID: 24274739 Stage-specific Inhibition of TrkB Activity Leads to Long-lasting and Sexually Dimorphic Effects on Body Weight and Hypothalamic Gene Expression PloS One. 2013 | Pubmed ID: 24312242 RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention Neuron. Oct, 2013 | Pubmed ID: 24139042 Protein Microarray Characterization of the S-nitrosoproteome Molecular & Cellular Proteomics : MCP. Oct, 2013 | Pubmed ID: 24105792 Estrogen-related Receptor Beta Deficiency Alters Body Composition and Response to Restraint Stress BMC Physiology. Sep, 2013 | Pubmed ID: 24053666 Rax Regulates Hypothalamic Tanycyte Differentiation and Barrier Function in Mice The Journal of Comparative Neurology. Aug, 2013 | Pubmed ID: 23939786 Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity Molecular & Cellular Proteomics : MCP. Oct, 2013 | Pubmed ID: 23824909 LHX2 is Necessary for the Maintenance of Optic Identity and for the Progression of Optic Morphogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2013 | Pubmed ID: 23595746 Identification of Hypothalamic Neuron-derived Neurotrophic Factor As a Novel Factor Modulating Appetite American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jun, 2013 | Pubmed ID: 23576617 Construction of Human Activity-based Phosphorylation Networks Molecular Systems Biology. 2013 | Pubmed ID: 23549483 Estrogen-related Receptor β Deletion Modulates Whole-body Energy Balance Via Estrogen-related Receptor γ and Attenuates Neuropeptide Y Gene Expression The European Journal of Neuroscience. Apr, 2013 | Pubmed ID: 23360481 High-throughput RNA in Situ Hybridization in Mouse Retina Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23150371 Functional Implications of Hypothalamic Neurogenesis in the Adult Mammalian Brain International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Dec, 2012 | Pubmed ID: 22867732 WITHDRAWN: Functional Implications of Hypothalamic Neurogenesis in the Adult Mammalian Brain International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Jul, 2012 | Pubmed ID: 22814121 Identification of New Autoantigens for Primary Biliary Cirrhosis Using Human Proteome Microarrays Molecular & Cellular Proteomics : MCP. Sep, 2012 | Pubmed ID: 22647870 Tanycytes of the Hypothalamic Median Eminence Form a Diet-responsive Neurogenic Niche Nature Neuroscience. May, 2012 | Pubmed ID: 22446882 Botch Promotes Neurogenesis by Antagonizing Notch Developmental Cell. Apr, 2012 | Pubmed ID: 22445366 Injury-independent Induction of Reactive Gliosis in Retina by Loss of Function of the LIM Homeodomain Transcription Factor Lhx2 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22393024 Identificación Rápida De Monoespecíficos Anticuerpos Monoclonales Utilizando Un Humano Microarray Proteoma Molecular & Cellular Proteomics : MCP. Feb, 2012 | Pubmed ID: 22307071 Reglamento De La CK2 Por La Fosforilación Y O-GlcNAcylation Revelado Por Semisíntesis Nature Chemical Biology. 2012 | Pubmed ID: 22267120 Levadura De Un Híbrido Ensayos Para Determinar La Asignación Centrada En Los Genes De Red De Regulación De Genes Humanos Nature Methods. Dec, 2011 | Pubmed ID: 22037702 El ARN No Codificador Largo Six3OS Hechos En Trans Para Regular El Desarrollo De La Retina Por Actividad Six3 Modulante Neural Development. 2011 | Pubmed ID: 21936910 Nos Contengo Multitudes: El Rostro Proteico Del Retinoblastoma Cancer Cell. Aug, 2011 | Pubmed ID: 21840479 La Transcripción Spalt Familia Sall3 Factor Regula El Desarrollo De Los Conos De La Retina Y Las Interneuronas Horizontales Development (Cambridge, England). Jun, 2011 | Pubmed ID: 21558380 Caracterización De Las Interacciones Proteína-ADN Utilizando Microarrays De Proteínas Cold Spring Harbor Protocols. May, 2011 | Pubmed ID: 21536762 Caracterización Sistemático De Las Interacciones Proteína-ADN Cellular and Molecular Life Sciences : CMLS. May, 2011 | Pubmed ID: 21207099 Región De Expresión De Genes Específicos En El Tálamo Del Ratón Postnatal Temprano The Journal of Comparative Neurology. Feb, 2011 | Pubmed ID: 21192083 Expresión Dinámica Espacio-temporal Del Gen En El Tálamo De Embriones De Ratón The Journal of Comparative Neurology. Feb, 2011 | Pubmed ID: 21192082 Proteína Funcional La Tecnología De Microarrays Wiley Interdisciplinary Reviews. Systems Biology and Medicine. May-Jun, 2011 | Pubmed ID: 20872749 Vías Moleculares Que Controlan El Desarrollo Del Tálamo Y El Hipotálamo: Especificación Neuronal Del Circuito De Formación The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2010 | Pubmed ID: 21068293 Pias3 Dependiente De Sumoylation Controla La Diferenciación De Los Mamíferos Fotorreceptora De Los Conos Nature Neuroscience. Sep, 2010 | Pubmed ID: 20729845 Tridimensional Difusión MicroImaging Tensor Para La Caracterización Anatómica Del Cerebro De Ratón Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Jul, 2010 | Pubmed ID: 20577980 El Huérfano Receptores Hormonales Nucleares ERRbeta Controla Rod Supervivencia De Los Fotorreceptores Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534447 El ARN No Codificador Largo RNCR2 Dirige Especificación Ratón Células De La Retina BMC Developmental Biology. 2010 | Pubmed ID: 20459797 Un Atlas Del Genoma De Ratón Para El Desarrollo Del Hipotálamo Nature Neuroscience. Jun, 2010 | Pubmed ID: 20436479 HPDI: Una Base De Datos Experimentales De Los Humanos Interacciones Proteína-DNA Bioinformatics (Oxford, England). Jan, 2010 | Pubmed ID: 19900953 Vertebrados De Retina Y Desarrollo Hipotálamo Wiley Interdisciplinary Reviews. Systems Biology and Medicine. Nov-Dec, 2009 | Pubmed ID: 20836003 Perfil De La Proteína Humana De ADN Revela Interactoma ERK2 Como Un Represor Transcripcional De Interferón Señalización Cell. Oct, 2009 | Pubmed ID: 19879846 Muscleblind Tipo 2: Expresión Circadiana En La Glándula Pineal De Mamíferos Está Controlada Por Un Mecanismo Adrenérgico-AMPc Journal of Neurochemistry. Jul, 2009 | Pubmed ID: 19457059 Un Nuevo Significado En El Mensaje: Los ARNs No Codificantes Y Su Papel En El Desarrollo De La Retina Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2009 | Pubmed ID: 19191220 Pias3 Dependiente De Sumoylation Dirige Rod Fotorreceptor Desarrollo Neuron. Jan, 2009 | Pubmed ID: 19186166 D-aspartato Y Oxidasa D-aspartato Mostrar Localización Selectiva Y Dinámica Desarrolladamente En La Retina Del Ratón Experimental Eye Research. Apr, 2008 | Pubmed ID: 18314103 Análisis Serial De Expresión Génica (SAGE): Método Experimental Y Análisis De Datos Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [et Al.]. Apr, 2007 | Pubmed ID: 18428405 Análisis Serial De Expresión Génica (SAGE): Método Experimental Y Análisis De Datos Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [et Al.]. Oct, 2007 | Pubmed ID: 18265400 Las Alteraciones Conductuales En Ratones Machos Que Carecían Del Gen Para La D-aspartato Oxidasa Behavioural Brain Research. Aug, 2006 | Pubmed ID: 16725213 D-aspartato Regula La Formación De Melanocortina Y Función: Alteraciones De La Conducta De D-aspartato Deficiencia De Oxidasa-ratones The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16525061 Metionina Adenosiltransferasa: Adrenérgico-AMPc Mecanismo Regula Un Ritmo Diario En La Expresión Pineal The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15504733 El Análisis De Agrupamiento De Los Datos De SAGE Utilizando Un Enfoque De Poisson Genome Biology. 2004 | Pubmed ID: 15239836 El Análisis Genómico Del Desarrollo De La Retina Del Ratón PLoS Biology. Sep, 2004 | Pubmed ID: 15226823 MicroSAGE Es Altamente Representativo Y Reproducible, Pero Muestra Grandes Diferencias En La Expresión Genética Entre Las Muestras Obtenidas De Tejidos Similares Genome Biology. 2003 | Pubmed ID: 12620102 Las Células Madre Que Conocen Su Lugar Nature Neuroscience. Dec, 2002 | Pubmed ID: 12447376 La Ceguera Hereditaria Asociada AIPL1 Proteína Interactúa Con La Proteína De La Célula Regulador Del Ciclo NUB1 Human Molecular Genetics. Oct, 2002 | Pubmed ID: 12374762 Las Mutaciones En El Deshidrogenasa Inosina Monofosfato Un Gen (IMPDH1) Causan La Forma RP10 De La Retinosis Pigmentaria Autosómica Dominante Human Molecular Genetics. Mar, 2002 | Pubmed ID: 11875050 La Aplicación De Las Tecnologías De Genómica Al Desarrollo Neuronal Current Opinion in Neurobiology. Feb, 2002 | Pubmed ID: 11861173 Perfil De Los Genes Que Se Expresan En La Retina Periférica Humana, La Mácula Y El Epitelio Pigmentario De La Retina a Través Del Análisis Serial De Expresión Génica (SAGE) Proceedings of the National Academy of Sciences of the United States of America. Jan, 2002 | Pubmed ID: 11756676 Poly(ADP-ribosyl)ation Basally Activated by DNA Strand Breaks Reflects Glutamate-nitric Oxide Neurotransmission Proceedings of the National Academy of Sciences of the United States of America. Feb, 2000 | Pubmed ID: 10677544 A Novel Neuron-enriched Homolog of the Erythrocyte Membrane Cytoskeletal Protein 4.1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 1999 | Pubmed ID: 10414974 Poly(ADP-ribose) Polymerase-deficient Mice Are Protected from Streptozotocin-induced Diabetes Proceedings of the National Academy of Sciences of the United States of America. Mar, 1999 | Pubmed ID: 10077636 The 13-kD FK506 Binding Protein, FKBP13, Interacts with a Novel Homologue of the Erythrocyte Membrane Cytoskeletal Protein 4.1 The Journal of Cell Biology. Apr, 1998 | Pubmed ID: 9531554 Parapinopsin, a Novel Catfish Opsin Localized to the Parapineal Organ, Defines a New Gene Family The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1997 | Pubmed ID: 9334384 Developmental Expression Pattern of Phototransduction Components in Mammalian Pineal Implies a Light-sensing Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1997 | Pubmed ID: 9334383 The Development of Excitatory Synapses in Cultured Spinal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 1997 | Pubmed ID: 9295380 Neuronal Nitric Oxide Synthase Alternatively Spliced Forms: Prominent Functional Localizations in the Brain Proceedings of the National Academy of Sciences of the United States of America. Apr, 1997 | Pubmed ID: 9096405 Análisis multiplexado de la expresión génica de la retina y la accesibilidad a la cromatina utilizando scRNA-Seq y scATAC-Seq Kurt Weir*1, Patrick Leavey*1, Clayton Santiago1, Seth Blackshaw1,2,3,4,5,6 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine JoVE 62239 Neuroscience Interrogatorio funcional de adultos hipotalámica neurogénesis con focal Radiológica Inhibición Daniel A. Lee1,2, Juan Salvatierra2, Esteban Velarde3, John Wong3, Eric C. Ford4, Seth Blackshaw2,5 1Division of Biology, California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 4Department of Radiation Oncology, University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine JoVE 50716 Neuroscience En electroporación in vivo de la retina del ratón en desarrollo Jimmy de Melo1, Seth Blackshaw1,2,3,4,5 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, 2Department of Neurology, Johns Hopkins School of Medicine, 3Department of Ophthalmology, Johns Hopkins School of Medicine, 4Center for High-Throughput Biology, Johns Hopkins School of Medicine, 5Institute for Cell Engineering, Johns Hopkins School of Medicine JoVE 2847 Neuroscience
Análisis multiplexado de la expresión génica de la retina y la accesibilidad a la cromatina utilizando scRNA-Seq y scATAC-Seq Kurt Weir*1, Patrick Leavey*1, Clayton Santiago1, Seth Blackshaw1,2,3,4,5,6 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine JoVE 62239 Neuroscience
Interrogatorio funcional de adultos hipotalámica neurogénesis con focal Radiológica Inhibición Daniel A. Lee1,2, Juan Salvatierra2, Esteban Velarde3, John Wong3, Eric C. Ford4, Seth Blackshaw2,5 1Division of Biology, California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 4Department of Radiation Oncology, University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine JoVE 50716 Neuroscience
En electroporación in vivo de la retina del ratón en desarrollo Jimmy de Melo1, Seth Blackshaw1,2,3,4,5 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, 2Department of Neurology, Johns Hopkins School of Medicine, 3Department of Ophthalmology, Johns Hopkins School of Medicine, 4Center for High-Throughput Biology, Johns Hopkins School of Medicine, 5Institute for Cell Engineering, Johns Hopkins School of Medicine JoVE 2847 Neuroscience