Shai Izraeli

Publications

• Perturbation of Fetal Hematopoiesis in a Mouse Model of Down Syndrome's Transient Myeloproliferative Disorder
  Blood. Aug, 2013  |   Pubmed ID: 23719302
• Interleukin 7 and Thymic Stromal Lymphopoietin: from Immunity to Leukemia
  Cellular and Molecular Life Sciences : CMLS. Apr, 2013  |   Pubmed ID: 23625073
• Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL
  Cell. Aug, 2012  |   Pubmed ID: 22863010
• Cell Lineage Analysis of Acute Leukemia Relapse Uncovers the Role of Replication-rate Heterogeneity and Microsatellite Instability
  Blood. Jul, 2012  |   Pubmed ID: 22645183
• Spontaneous Remission of Childhood Acute Marrow Fibrosis and Megakaryoblastic Leukemia
  Journal of Pediatric Hematology/oncology. Oct, 2012  |   Pubmed ID: 22627572
• DYRK1A in Down Syndrome: an Oncogene or Tumor Suppressor?
  The Journal of Clinical Investigation. Mar, 2012  |   Pubmed ID: 22354166
• STIL is Required for Centriole Duplication in Human Cells
  Journal of Cell Science. Mar, 2012  |   Pubmed ID: 22349705
• A Phenanthrene Derived PARP Inhibitor is an Extra-centrosomes De-clustering Agent Exclusively Eradicating Human Cancer Cells
  BMC Cancer. 2011  |   Pubmed ID: 21943092
• Large-scale Analysis of Chromosomal Aberrations in Cancer Karyotypes Reveals Two Distinct Paths to Aneuploidy
  Genome Biology. 2011  |   Pubmed ID: 21714908
• ERG Promotes T-acute Lymphoblastic Leukemia and is Transcriptionally Regulated in Leukemic Cells by a Stem Cell Enhancer
  Blood. Jun, 2011  |   Pubmed ID: 21536859
• Gain-of-function Mutations in Interleukin-7 Receptor-α (IL7R) in Childhood Acute Lymphoblastic Leukemias
  The Journal of Experimental Medicine. May, 2011  |   Pubmed ID: 21536738
• The Stil Protein Regulates Centrosome Integrity and Mitosis Through Suppression of Chfr
  Journal of Cell Science. Feb, 2011  |   Pubmed ID: 21245198
• Therapy-related Acute Myeloid Leukemia with T(2;11)(q37;q23) After Treatment for Osteosarcoma
  Cancer Genetics and Cytogenetics. Dec, 2010  |   Pubmed ID: 21156246
• Similar Yet Different
  Blood. Aug, 2010  |   Pubmed ID: 20724545
• Detection of Prognostically Relevant Genetic Abnormalities in Childhood B-cell Precursor Acute Lymphoblastic Leukaemia: Recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster Study Group
  British Journal of Haematology. Oct, 2010  |   Pubmed ID: 20701601
• Application of Genomics for Risk Stratification of Childhood Acute Lymphoblastic Leukaemia: from Bench to Bedside?
  British Journal of Haematology. Oct, 2010  |   Pubmed ID: 20678159
• Prospective Comparison of Two Flow Cytometry Methodologies for Monitoring Minimal Residual Disease in a Multicenter Treatment Protocol of Childhood Acute Lymphoblastic Leukemia
  Cytometry. Part B, Clinical Cytometry. Nov, 2010  |   Pubmed ID: 20632326
• Presence of the P2RY8-CRLF2 Rearrangement is Associated with a Poor Prognosis in Non-high-risk Precursor B-cell Acute Lymphoblastic Leukemia in Children Treated According to the ALL-BFM 2000 Protocol
  Blood. Jul, 2010  |   Pubmed ID: 20378752
• Where Can Biology of Childhood ALL Be Attacked by New Compounds?
  Cancer Treatment Reviews. Jun, 2010  |   Pubmed ID: 20223597
• A Rare Case of GATA1 Negative Chemoresistant Acute Megakaryocytic Leukemia in an 8-month-old Infant with Trisomy 21
  Pediatric Blood & Cancer. Jul, 2010  |   Pubmed ID: 20108342
• Down Syndrome Acute Lymphoblastic Leukemia, a Highly Heterogeneous Disease in Which Aberrant Expression of CRLF2 is Associated with Mutated JAK2: a Report from the International BFM Study Group
  Blood. Feb, 2010  |   Pubmed ID: 19965641
• Detection of Residual B Precursor Lymphoblastic Leukemia by Uniform Gating Flow Cytometry
  Pediatric Blood & Cancer. Jan, 2010  |   Pubmed ID: 19760767
• A Selective Eradication of Human Nonhereditary Breast Cancer Cells by Phenanthridine-derived PolyADP-ribose Polymerase Inhibitors
  Breast Cancer Research : BCR. 2009  |   Pubmed ID: 19891779
• Extended Triple Intrathecal Therapy in Children with T-cell Acute Lymphoblastic Leukaemia: a Report from the Israeli National ALL-Studies
  British Journal of Haematology. Oct, 2009  |   Pubmed ID: 19694717
• ERG is a Megakaryocytic Oncogene
  Cancer Research. Jun, 2009  |   Pubmed ID: 19487285
• Constitutional Aneuploidy and Cancer Predisposition
  Human Molecular Genetics. Apr, 2009  |   Pubmed ID: 19297405
• Diagnostic Assay Based on Hsa-miR-205 Expression Distinguishes Squamous from Nonsquamous Non-small-cell Lung Carcinoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2009  |   Pubmed ID: 19273703
• The Expression of Three Genes in Primary Non-small Cell Lung Cancer is Associated with Metastatic Spread to the Brain
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2009  |   Pubmed ID: 19190132
• Insights into the Manifestations, Outcomes, and Mechanisms of Leukemogenesis in Down Syndrome
  Blood. Mar, 2009  |   Pubmed ID: 19139078
• Prevalence and Clinical Correlates of JAK2 Mutations in Down Syndrome Acute Lymphoblastic Leukaemia
  British Journal of Haematology. Mar, 2009  |   Pubmed ID: 19120350
• Trisomy 21 Tilts the Balance
  Blood. Dec, 2008  |   Pubmed ID: 19029447
• Mutations of JAK2 in Acute Lymphoblastic Leukaemias Associated with Down's Syndrome
  Lancet. Oct, 2008  |   Pubmed ID: 18805579
• The Mitotic Checkpoint Gene, SIL is Regulated by E2F1
  International Journal of Cancer. Journal International Du Cancer. Oct, 2008  |   Pubmed ID: 18649360
• Array Comparative Genome Hybridization Analysis of Acute Lymphoblastic Leukaemia and Acute Megakaryoblastic Leukaemia in Patients with Down Syndrome
  British Journal of Haematology. Sep, 2008  |   Pubmed ID: 18557744
• ETV6-NCOA2: a Novel Fusion Gene in Acute Leukemia Associated with Coexpression of T-lymphoid and Myeloid Markers and Frequent NOTCH1 Mutations
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008  |   Pubmed ID: 18281529
• Integration of a Palliative and Terminal Care Center into a Comprehensive Pediatric Oncology Department
  Pediatric Blood & Cancer. May, 2008  |   Pubmed ID: 18240176
• Cytogenetic Features of Acute Lymphoblastic and Myeloid Leukemias in Pediatric Patients with Down Syndrome: an IBFM-SG Study
  Blood. Feb, 2008  |   Pubmed ID: 17971484
• Acute Lymphoblastic Leukemia in Children: Correlation of Musculoskeletal Manifestations and Immunophenotypes
  Journal of Children's Orthopaedics. Mar, 2007  |   Pubmed ID: 19308508
• Biased Exonization of Transposed Elements in Duplicated Genes: A Lesson from the TIF-IA Gene
  BMC Molecular Biology. 2007  |   Pubmed ID: 18047649
• High Interleukin-15 Expression Characterizes Childhood Acute Lymphoblastic Leukemia with Involvement of the CNS
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2007  |   Pubmed ID: 17947730
• Trisomy of Chromosome 21 in Leukemogenesis
  Blood Cells, Molecules & Diseases. Sep-Oct, 2007  |   Pubmed ID: 17532652
• STOP: Searching for Transcription Factor Motifs Using Gene Expression
  Bioinformatics (Oxford, England). Jul, 2007  |   Pubmed ID: 17488754
• The SIL Gene is Essential for Mitotic Entry and Survival of Cancer Cells
  Cancer Research. May, 2007  |   Pubmed ID: 17456584
• Prediction of Chromosomal Aneuploidy from Gene Expression Data
  Genes, Chromosomes & Cancer. Jan, 2007  |   Pubmed ID: 17044051
• The SCL 3' Enhancer Responds to Hedgehog Signaling During Hemangioblast Specification
  Experimental Hematology. Dec, 2006  |   Pubmed ID: 17157160
• Down's Syndrome As a Model of a Pre-leukemic Condition
  Haematologica. Nov, 2006  |   Pubmed ID: 17082004
• Molecular Pathways Regulating Pro-migratory Effects of Hedgehog Signaling
  The Journal of Biological Chemistry. Nov, 2006  |   Pubmed ID: 16943197
• Myeloid Dysplasia in Familial 3-methylglutaconic Aciduria
  Journal of Pediatric Hematology/oncology. Feb, 2006  |   Pubmed ID: 16462576
• Perspective: Chromosomal Aneuploidy in Leukemia--lessons from Down Syndrome
  Hematological Oncology. Mar, 2006  |   Pubmed ID: 16270377
• Epidermal Growth Factor Receptor Gene Amplification and Expression in Disseminated Pediatric Low-grade Gliomas
  Journal of Neurosurgery. Oct, 2005  |   Pubmed ID: 16270688
• Chromosome Copy Number and Leukemia-lessons from Down's Syndrome
  Hematology (Amsterdam, Netherlands). 2005  |   Pubmed ID: 16188662
• The Proto-oncogene ERG in Megakaryoblastic Leukemias
  Cancer Research. Sep, 2005  |   Pubmed ID: 16140924
• Sil Phosphorylation in a Pin1 Binding Domain Affects the Duration of the Spindle Checkpoint
  Molecular and Cellular Biology. Aug, 2005  |   Pubmed ID: 16024801
• Gene Expression Analysis Reveals a Strong Signature of an Interferon-induced Pathway in Childhood Lymphoblastic Leukemia As Well As in Breast and Ovarian Cancer
  Oncogene. Sep, 2005  |   Pubmed ID: 16007187
• Co-existence of Multiple Subclones in TEL-AML1 at Diagnosis of Acute Lymphoblastic Leukaemia in Association with Submicroscopic Deletion of AML1
  British Journal of Haematology. May, 2005  |   Pubmed ID: 15877731
• Histone Deacetylase Inhibitors--a New Tool to Treat Cancer
  Cancer Treatment Reviews. Aug, 2004  |   Pubmed ID: 15245778
• Leukaemia -- a Developmental Perspective
  British Journal of Haematology. Jul, 2004  |   Pubmed ID: 15198727
• Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Current Status and Challenges
  Acta Haematologica. 2004  |   Pubmed ID: 15179003
• Mitochondrial Pro-apoptotic ARTS Protein is Lost in the Majority of Acute Lymphoblastic Leukemia Patients
  Oncogene. Jul, 2004  |   Pubmed ID: 15122323
• Sil Overexpression in Lung Cancer Characterizes Tumors with Increased Mitotic Activity
  Oncogene. Jul, 2004  |   Pubmed ID: 15107824
• Kidney, Blood, and Endothelium: Developmental Expression of Stem Cell Leukemia During Nephrogenesis
  Kidney International. Apr, 2004  |   Pubmed ID: 15086455
• Congenital Syndromes and Leukemia: Clues to Pathogenesis
  Reviews in Clinical and Experimental Hematology. Sep, 2003  |   Pubmed ID: 15024968
• Mutations in Exon 2 of GATA1 Are Early Events in Megakaryocytic Malignancies Associated with Trisomy 21
  Blood. Aug, 2003  |   Pubmed ID: 12649131
• Cancer Research--from Bench to Bedside
  The Israel Medical Association Journal : IMAJ. Sep, 2002  |   Pubmed ID: 12440253
• Molecular Medicine--an Overview
  The Israel Medical Association Journal : IMAJ. Aug, 2002  |   Pubmed ID: 12183874
• GLI3 is Not Mutated Commonly in Sporadic Medulloblastomas
  Cancer. Jul, 2002  |   Pubmed ID: 12115313