Shai Izraeli Cancer Research Center Sheba Medical Center Biography Publications Institution JoVE Articles Shai Izraeli has not added a biography. If you are Shai Izraeli and would like to personalize this page please email our Author Liaison for assistance. Publications Perturbation of Fetal Hematopoiesis in a Mouse Model of Down Syndrome's Transient Myeloproliferative Disorder Blood. Aug, 2013 | Pubmed ID: 23719302 Interleukin 7 and Thymic Stromal Lymphopoietin: from Immunity to Leukemia Cellular and Molecular Life Sciences : CMLS. Apr, 2013 | Pubmed ID: 23625073 Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL Cell. Aug, 2012 | Pubmed ID: 22863010 Cell Lineage Analysis of Acute Leukemia Relapse Uncovers the Role of Replication-rate Heterogeneity and Microsatellite Instability Blood. Jul, 2012 | Pubmed ID: 22645183 Spontaneous Remission of Childhood Acute Marrow Fibrosis and Megakaryoblastic Leukemia Journal of Pediatric Hematology/oncology. Oct, 2012 | Pubmed ID: 22627572 DYRK1A in Down Syndrome: an Oncogene or Tumor Suppressor? The Journal of Clinical Investigation. Mar, 2012 | Pubmed ID: 22354166 STIL is Required for Centriole Duplication in Human Cells Journal of Cell Science. Mar, 2012 | Pubmed ID: 22349705 A Phenanthrene Derived PARP Inhibitor is an Extra-centrosomes De-clustering Agent Exclusively Eradicating Human Cancer Cells BMC Cancer. 2011 | Pubmed ID: 21943092 Large-scale Analysis of Chromosomal Aberrations in Cancer Karyotypes Reveals Two Distinct Paths to Aneuploidy Genome Biology. 2011 | Pubmed ID: 21714908 ERG Promotes T-acute Lymphoblastic Leukemia and is Transcriptionally Regulated in Leukemic Cells by a Stem Cell Enhancer Blood. Jun, 2011 | Pubmed ID: 21536859 Gain-of-function Mutations in Interleukin-7 Receptor-α (IL7R) in Childhood Acute Lymphoblastic Leukemias The Journal of Experimental Medicine. May, 2011 | Pubmed ID: 21536738 The Stil Protein Regulates Centrosome Integrity and Mitosis Through Suppression of Chfr Journal of Cell Science. Feb, 2011 | Pubmed ID: 21245198 Therapy-related Acute Myeloid Leukemia with T(2;11)(q37;q23) After Treatment for Osteosarcoma Cancer Genetics and Cytogenetics. Dec, 2010 | Pubmed ID: 21156246 Similar Yet Different Blood. Aug, 2010 | Pubmed ID: 20724545 Detection of Prognostically Relevant Genetic Abnormalities in Childhood B-cell Precursor Acute Lymphoblastic Leukaemia: Recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster Study Group British Journal of Haematology. Oct, 2010 | Pubmed ID: 20701601 Application of Genomics for Risk Stratification of Childhood Acute Lymphoblastic Leukaemia: from Bench to Bedside? British Journal of Haematology. Oct, 2010 | Pubmed ID: 20678159 Prospective Comparison of Two Flow Cytometry Methodologies for Monitoring Minimal Residual Disease in a Multicenter Treatment Protocol of Childhood Acute Lymphoblastic Leukemia Cytometry. Part B, Clinical Cytometry. Nov, 2010 | Pubmed ID: 20632326 Presence of the P2RY8-CRLF2 Rearrangement is Associated with a Poor Prognosis in Non-high-risk Precursor B-cell Acute Lymphoblastic Leukemia in Children Treated According to the ALL-BFM 2000 Protocol Blood. Jul, 2010 | Pubmed ID: 20378752 Where Can Biology of Childhood ALL Be Attacked by New Compounds? Cancer Treatment Reviews. Jun, 2010 | Pubmed ID: 20223597 A Rare Case of GATA1 Negative Chemoresistant Acute Megakaryocytic Leukemia in an 8-month-old Infant with Trisomy 21 Pediatric Blood & Cancer. Jul, 2010 | Pubmed ID: 20108342 Down Syndrome Acute Lymphoblastic Leukemia, a Highly Heterogeneous Disease in Which Aberrant Expression of CRLF2 is Associated with Mutated JAK2: a Report from the International BFM Study Group Blood. Feb, 2010 | Pubmed ID: 19965641 Detection of Residual B Precursor Lymphoblastic Leukemia by Uniform Gating Flow Cytometry Pediatric Blood & Cancer. Jan, 2010 | Pubmed ID: 19760767 A Selective Eradication of Human Nonhereditary Breast Cancer Cells by Phenanthridine-derived PolyADP-ribose Polymerase Inhibitors Breast Cancer Research : BCR. 2009 | Pubmed ID: 19891779 Extended Triple Intrathecal Therapy in Children with T-cell Acute Lymphoblastic Leukaemia: a Report from the Israeli National ALL-Studies British Journal of Haematology. Oct, 2009 | Pubmed ID: 19694717 ERG is a Megakaryocytic Oncogene Cancer Research. Jun, 2009 | Pubmed ID: 19487285 Constitutional Aneuploidy and Cancer Predisposition Human Molecular Genetics. Apr, 2009 | Pubmed ID: 19297405 Diagnostic Assay Based on Hsa-miR-205 Expression Distinguishes Squamous from Nonsquamous Non-small-cell Lung Carcinoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2009 | Pubmed ID: 19273703 The Expression of Three Genes in Primary Non-small Cell Lung Cancer is Associated with Metastatic Spread to the Brain Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2009 | Pubmed ID: 19190132 Insights into the Manifestations, Outcomes, and Mechanisms of Leukemogenesis in Down Syndrome Blood. Mar, 2009 | Pubmed ID: 19139078 Prevalence and Clinical Correlates of JAK2 Mutations in Down Syndrome Acute Lymphoblastic Leukaemia British Journal of Haematology. Mar, 2009 | Pubmed ID: 19120350 Trisomy 21 Tilts the Balance Blood. Dec, 2008 | Pubmed ID: 19029447 Mutations of JAK2 in Acute Lymphoblastic Leukaemias Associated with Down's Syndrome Lancet. Oct, 2008 | Pubmed ID: 18805579 The Mitotic Checkpoint Gene, SIL is Regulated by E2F1 International Journal of Cancer. Journal International Du Cancer. Oct, 2008 | Pubmed ID: 18649360 Array Comparative Genome Hybridization Analysis of Acute Lymphoblastic Leukaemia and Acute Megakaryoblastic Leukaemia in Patients with Down Syndrome British Journal of Haematology. Sep, 2008 | Pubmed ID: 18557744 ETV6-NCOA2: a Novel Fusion Gene in Acute Leukemia Associated with Coexpression of T-lymphoid and Myeloid Markers and Frequent NOTCH1 Mutations Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008 | Pubmed ID: 18281529 Integration of a Palliative and Terminal Care Center into a Comprehensive Pediatric Oncology Department Pediatric Blood & Cancer. May, 2008 | Pubmed ID: 18240176 Cytogenetic Features of Acute Lymphoblastic and Myeloid Leukemias in Pediatric Patients with Down Syndrome: an IBFM-SG Study Blood. Feb, 2008 | Pubmed ID: 17971484 Acute Lymphoblastic Leukemia in Children: Correlation of Musculoskeletal Manifestations and Immunophenotypes Journal of Children's Orthopaedics. Mar, 2007 | Pubmed ID: 19308508 Biased Exonization of Transposed Elements in Duplicated Genes: A Lesson from the TIF-IA Gene BMC Molecular Biology. 2007 | Pubmed ID: 18047649 High Interleukin-15 Expression Characterizes Childhood Acute Lymphoblastic Leukemia with Involvement of the CNS Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2007 | Pubmed ID: 17947730 Trisomy of Chromosome 21 in Leukemogenesis Blood Cells, Molecules & Diseases. Sep-Oct, 2007 | Pubmed ID: 17532652 STOP: Searching for Transcription Factor Motifs Using Gene Expression Bioinformatics (Oxford, England). Jul, 2007 | Pubmed ID: 17488754 The SIL Gene is Essential for Mitotic Entry and Survival of Cancer Cells Cancer Research. May, 2007 | Pubmed ID: 17456584 Prediction of Chromosomal Aneuploidy from Gene Expression Data Genes, Chromosomes & Cancer. Jan, 2007 | Pubmed ID: 17044051 The SCL 3' Enhancer Responds to Hedgehog Signaling During Hemangioblast Specification Experimental Hematology. Dec, 2006 | Pubmed ID: 17157160 Down's Syndrome As a Model of a Pre-leukemic Condition Haematologica. Nov, 2006 | Pubmed ID: 17082004 Molecular Pathways Regulating Pro-migratory Effects of Hedgehog Signaling The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 16943197 Myeloid Dysplasia in Familial 3-methylglutaconic Aciduria Journal of Pediatric Hematology/oncology. Feb, 2006 | Pubmed ID: 16462576 Perspective: Chromosomal Aneuploidy in Leukemia--lessons from Down Syndrome Hematological Oncology. Mar, 2006 | Pubmed ID: 16270377 Epidermal Growth Factor Receptor Gene Amplification and Expression in Disseminated Pediatric Low-grade Gliomas Journal of Neurosurgery. Oct, 2005 | Pubmed ID: 16270688 Chromosome Copy Number and Leukemia-lessons from Down's Syndrome Hematology (Amsterdam, Netherlands). 2005 | Pubmed ID: 16188662 The Proto-oncogene ERG in Megakaryoblastic Leukemias Cancer Research. Sep, 2005 | Pubmed ID: 16140924 Sil Phosphorylation in a Pin1 Binding Domain Affects the Duration of the Spindle Checkpoint Molecular and Cellular Biology. Aug, 2005 | Pubmed ID: 16024801 Gene Expression Analysis Reveals a Strong Signature of an Interferon-induced Pathway in Childhood Lymphoblastic Leukemia As Well As in Breast and Ovarian Cancer Oncogene. Sep, 2005 | Pubmed ID: 16007187 Co-existence of Multiple Subclones in TEL-AML1 at Diagnosis of Acute Lymphoblastic Leukaemia in Association with Submicroscopic Deletion of AML1 British Journal of Haematology. May, 2005 | Pubmed ID: 15877731 Histone Deacetylase Inhibitors--a New Tool to Treat Cancer Cancer Treatment Reviews. Aug, 2004 | Pubmed ID: 15245778 Leukaemia -- a Developmental Perspective British Journal of Haematology. Jul, 2004 | Pubmed ID: 15198727 Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Current Status and Challenges Acta Haematologica. 2004 | Pubmed ID: 15179003 Mitochondrial Pro-apoptotic ARTS Protein is Lost in the Majority of Acute Lymphoblastic Leukemia Patients Oncogene. Jul, 2004 | Pubmed ID: 15122323 Sil Overexpression in Lung Cancer Characterizes Tumors with Increased Mitotic Activity Oncogene. Jul, 2004 | Pubmed ID: 15107824 Kidney, Blood, and Endothelium: Developmental Expression of Stem Cell Leukemia During Nephrogenesis Kidney International. Apr, 2004 | Pubmed ID: 15086455 Congenital Syndromes and Leukemia: Clues to Pathogenesis Reviews in Clinical and Experimental Hematology. Sep, 2003 | Pubmed ID: 15024968 Mutations in Exon 2 of GATA1 Are Early Events in Megakaryocytic Malignancies Associated with Trisomy 21 Blood. Aug, 2003 | Pubmed ID: 12649131 Cancer Research--from Bench to Bedside The Israel Medical Association Journal : IMAJ. Sep, 2002 | Pubmed ID: 12440253 Molecular Medicine--an Overview The Israel Medical Association Journal : IMAJ. Aug, 2002 | Pubmed ID: 12183874 GLI3 is Not Mutated Commonly in Sporadic Medulloblastomas Cancer. Jul, 2002 | Pubmed ID: 12115313 Cell Death mit Abnormal Mitose Assoziierte Beobachtet von konfokalen Imaging im Live Cancer Cells Asher Castiel1, Leonid Visochek2,3, Leonid Mittelman4, Yael Zilberstein4, Francoise Dantzer5, Shai Izraeli1,6, Malka Cohen-Armon2,3 1Cancer Research Center, Sheba Medical Center, 2The Neufeld Cardiac Research Institute, Tel-Aviv University, 3Department of Physiology and Pharmacology, Tel-Aviv University, 4Imaging Unit, Sackler Faculty of Medicine, Tel-Aviv University, 5Biotechnology and Cell Signaling, Ecole Superieure de Biotechnologie Strasbourg, 6Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University JoVE 50568 Medicine
Cell Death mit Abnormal Mitose Assoziierte Beobachtet von konfokalen Imaging im Live Cancer Cells Asher Castiel1, Leonid Visochek2,3, Leonid Mittelman4, Yael Zilberstein4, Francoise Dantzer5, Shai Izraeli1,6, Malka Cohen-Armon2,3 1Cancer Research Center, Sheba Medical Center, 2The Neufeld Cardiac Research Institute, Tel-Aviv University, 3Department of Physiology and Pharmacology, Tel-Aviv University, 4Imaging Unit, Sackler Faculty of Medicine, Tel-Aviv University, 5Biotechnology and Cell Signaling, Ecole Superieure de Biotechnologie Strasbourg, 6Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University JoVE 50568 Medicine
