Shibo Jiang Lindsley F. Kimball Research Institute New York Blood Center Biography Publications Institution JoVE Articles Shibo Jiang has not added a biography. If you are Shibo Jiang and would like to personalize this page please email our Author Liaison for assistance. Publications What Can Academia Learn from XMRV Studies? Nature Reviews. Urology. Feb, 2012 | Pubmed ID: 22331091 Design, Synthesis and Biological Evaluation of 1-[(2-benzyloxyl/alkoxyl) Methyl]-5-halo-6-aryluracils As Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Improved Drug Resistance Profile Journal of Medicinal Chemistry. Jan, 2012 | Pubmed ID: 22283377 A Natural Theaflavins Preparation Inhibits HIV-1 Infection by Targeting the Entry Step: Potential Applications for Preventing HIV-1 Infection Fitoterapia. Mar, 2012 | Pubmed ID: 22155187 Mutations of Gln64 in the HIV-1 Gp41 N-terminal Heptad Repeat Render Viruses Resistant to Peptide HIV Fusion Inhibitors Targeting the Gp41 Pocket Journal of Virology. Jan, 2012 | Pubmed ID: 22013063 Identification of HBsAg-specific Antibodies from a Mammalian Cell Displayed Full-length Human Antibody Library of Healthy Immunized Donor Cellular & Molecular Immunology. Dec, 2011 | Pubmed ID: 22179672 Interactions Between Different Generation HIV-1 Fusion Inhibitors and the Putative Mechanism Underlying the Synergistic Anti-HIV-1 Effect Resulting from Their Combination The FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2011 | Pubmed ID: 22085645 HIV-1 Glycoprotein 41 Ectodomain Induces Activation of the CD74 Protein-mediated Extracellular Signal-regulated Kinase/mitogen-activated Protein Kinase Pathway to Enhance Viral Infection The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 22039051 Design, Synthesis and Biological Evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles As Novel Potential HIV-1 Gp41 Inhibitors Bioorganic & Medicinal Chemistry. Nov, 2011 | Pubmed ID: 22014749 Design, Synthesis, and Biological Activity of a Novel Series of 2,5-disubstituted Furans/pyrroles As HIV-1 Fusion Inhibitors Targeting Gp41 Bioorganic & Medicinal Chemistry Letters. Nov, 2011 | Pubmed ID: 21978673 Heteromeric Assembled Polypeptidic Artificial Hydrolases with a Six-helical Bundle Scaffold Chembiochem : a European Journal of Chemical Biology. Nov, 2011 | Pubmed ID: 21957084 A Novel Chimeric Protein-based HIV-1 Fusion Inhibitor Targeting Gp41 Glycoprotein with High Potency and Stability The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21690094 An Amphiphilic Conjugate Approach Toward the Design and Synthesis of Betulinic Acid-polyphenol Conjugates As Inhibitors of the HIV-1 Gp41 Fusion Core Formation ChemMedChem. Sep, 2011 | Pubmed ID: 21688394 HIV-1 Gp41 Ectodomain Enhances Cryptococcus Neoformans Binding to Human Brain Microvascular Endothelial Cells Via Gp41 Core-induced Membrane Activities The Biochemical Journal. Sep, 2011 | Pubmed ID: 21668410 CL-385319 Inhibits H5N1 Avian Influenza A Virus Infection by Blocking Viral Entry European Journal of Pharmacology. Jun, 2011 | Pubmed ID: 21536025 HIV-1 Gp41 Core with Exposed Membrane-proximal External Region Inducing Broad HIV-1 Neutralizing Antibodies PloS One. 2011 | Pubmed ID: 21483871 Complement Inhibition Alleviates Paraquat-induced Acute Lung Injury American Journal of Respiratory Cell and Molecular Biology. Oct, 2011 | Pubmed ID: 21421909 Susceptibility of HIV-1 Subtypes B', CRF07_BC and CRF01_AE That Are Predominantly Circulating in China to HIV-1 Entry Inhibitors PloS One. 2011 | Pubmed ID: 21412427 Discovery of a Potent Peptidic Cyclophilin A Inhibitor Trp-Gly-Pro European Journal of Medicinal Chemistry. May, 2011 | Pubmed ID: 21396746 A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-clade Protection Against Divergent H5N1 Viruses PloS One. 2011 | Pubmed ID: 21304591 HIV-associated Dementia in the Era of Highly Active Antiretroviral Therapy (HAART) Microbes and Infection / Institut Pasteur. May, 2011 | Pubmed ID: 21262373 Four-way Ligation for Construction of a Mammalian Cell-based Full-length Antibody Display Library Acta Biochimica Et Biophysica Sinica. Mar, 2011 | Pubmed ID: 21257624 Combinations of 3-hydroxyphthalic Anhydride-modified Ovalbumin with Antiretroviral Drug-based Microbicide Candidates Display Synergistic and Complementary Effects Against HIV-1 Infection Journal of Acquired Immune Deficiency Syndromes (1999). Apr, 2011 | Pubmed ID: 21239999 Design, Synthesis, and Biological Activity of Novel 5-((arylfuran/1H-pyrrol-2-yl)methylene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-ones As HIV-1 Fusion Inhibitors Targeting Gp41 Journal of Medicinal Chemistry. Jan, 2011 | Pubmed ID: 21190369 In Vitro Selection and Characterization of HIV-1 Variants with Increased Resistance to Sifuvirtide, a Novel HIV-1 Fusion Inhibitor The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21098485 Roles of the Hemagglutinin of Influenza A Virus in Viral Entry and Development of Antiviral Therapeutics and Vaccines Protein & Cell. Apr, 2010 | Pubmed ID: 21203946 Design, Synthesis, and Evaluation of Diarylpyridines and Diarylanilines As Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Journal of Medicinal Chemistry. Nov, 2010 | Pubmed ID: 21049929 Potent and Persistent Antibody Responses Against the Receptor-binding Domain of SARS-CoV Spike Protein in Recovered Patients Virology Journal. 2010 | Pubmed ID: 21047436 Development of Peptide and Small-molecule HIV-1 Fusion Inhibitors That Target Gp41 ChemMedChem. Nov, 2010 | Pubmed ID: 20845360 Induction of Protection Against Divergent H5N1 Influenza Viruses Using a Recombinant Fusion Protein Linking Influenza M2e to Onchocerca Volvulus Activation Associated Protein-1 (ASP-1) Adjuvant Vaccine. Oct, 2010 | Pubmed ID: 20732469 A Novel Strategy for Rapid Construction of Libraries of Full-length Antibodies Highly Expressed on Mammalian Cell Surfaces Acta Biochimica Et Biophysica Sinica. Aug, 2010 | Pubmed ID: 20705599 Development of a Safe and Convenient Neutralization Assay for Rapid Screening of Influenza HA-specific Neutralizing Monoclonal Antibodies Biochemical and Biophysical Research Communications. Jun, 2010 | Pubmed ID: 20685351 An H5N1 M2e-based Multiple Antigenic Peptide Vaccine Confers Heterosubtypic Protection from Lethal Infection with Pandemic 2009 H1N1 Virus Virology Journal. 2010 | Pubmed ID: 20624292 Development of a Safe and Convenient Neutralization Assay for Rapid Screening of Influenza HA-specific Neutralizing Monoclonal Antibodies Biochemical and Biophysical Research Communications. Jul, 2010 | Pubmed ID: 20617558 A Recombinant Mimetics of the HIV-1 Gp41 Prehairpin Fusion Intermediate Fused with Human IgG Fc Fragment Elicits Neutralizing Antibody Response in the Vaccinated Mice Biochemical and Biophysical Research Communications. Jul, 2010 | Pubmed ID: 20599765 Tricyclononene Carboxamide Derivatives As Novel Anti-HIV-1 Agents European Journal of Medicinal Chemistry. Sep, 2010 | Pubmed ID: 20598780 Identification of a Gp41 Core-binding Molecule with Homologous Sequence of Human TNNI3K-like Protein As a Novel Human Immunodeficiency Virus Type 1 Entry Inhibitor Journal of Virology. Sep, 2010 | Pubmed ID: 20592080 Novel Recombinant Engineered Gp41 N-terminal Heptad Repeat Trimers and Their Potential As Anti-HIV-1 Therapeutics or Microbicides The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20538590 Diarylaniline Derivatives As a Distinct Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors Journal of Medicinal Chemistry. Jul, 2010 | Pubmed ID: 20527972 Maleic Anhydride-modified Chicken Ovalbumin As an Effective and Inexpensive Anti-HIV Microbicide Candidate for Prevention of HIV Sexual Transmission Retrovirology. 2010 | Pubmed ID: 20420669 A 219-mer CHO-expressing Receptor-binding Domain of SARS-CoV S Protein Induces Potent Immune Responses and Protective Immunity Viral Immunology. Apr, 2010 | Pubmed ID: 20374001 Potent and Broad Neutralizing Activity of a Single Chain Antibody Fragment Against Cell-free and Cell-associated HIV-1 MAbs. May-Jun, 2010 | Pubmed ID: 20305395 Genomic Signature and Mutation Trend Analysis of Pandemic (H1N1) 2009 Influenza A Virus PloS One. 2010 | Pubmed ID: 20221396 HIV-1 Gp41 Fusion Intermediate: a Target for HIV Therapeutics Journal of the Formosan Medical Association = Taiwan Yi Zhi. Feb, 2010 | Pubmed ID: 20206833 3-hydroxyphthalic Anhydride-modified Chicken Ovalbumin Exhibits Potent and Broad Anti-HIV-1 Activity: a Potential Microbicide for Preventing Sexual Transmission of HIV-1 Antimicrobial Agents and Chemotherapy. May, 2010 | Pubmed ID: 20194691 HIV Type 1 B'/C Recombinant (CRF07_BC) in Virologic Noncontrollers Elicits Neutralizing Antibodies Against Heterologous but Not Autologous Viruses AIDS Research and Human Retroviruses. Feb, 2010 | Pubmed ID: 20156107 Association of Candidate Susceptible Loci with Chronic Infection with Hepatitis B Virus in a Chinese Population Journal of Medical Virology. Mar, 2010 | Pubmed ID: 20087947 An M2e-based Multiple Antigenic Peptide Vaccine Protects Mice from Lethal Challenge with Divergent H5N1 Influenza Viruses Virology Journal. 2010 | Pubmed ID: 20082709 Research and Development of Universal Influenza Vaccines Microbes and Infection / Institut Pasteur. Apr, 2010 | Pubmed ID: 20079871 Structure-based Design, Synthesis and Biological Evaluation of New N-carboxyphenylpyrrole Derivatives As HIV Fusion Inhibitors Targeting Gp41 Bioorganic & Medicinal Chemistry Letters. Jan, 2010 | Pubmed ID: 19932616 E14-F55 Combination in M2 Protein: a Putative Molecular Determinant Responsible for Swine-origin Influenza A Virus Transmission in Humans PLoS Currents. 2009 | Pubmed ID: 20029615 ADS-J1 Inhibits Human Immunodeficiency Virus Type 1 Entry by Interacting with the Gp41 Pocket Region and Blocking Fusion-active Gp41 Core Formation Antimicrobial Agents and Chemotherapy. Dec, 2009 | Pubmed ID: 19786602 Design, Synthesis, and Structure-activity Relationship of a Novel Series of 2-aryl 5-(4-oxo-3-phenethyl-2-thioxothiazolidinylidenemethyl)furans As HIV-1 Entry Inhibitors Journal of Medicinal Chemistry. Dec, 2009 | Pubmed ID: 19746983 Recombinant Receptor-binding Domain of SARS-CoV Spike Protein Expressed in Mammalian, Insect and E. Coli Cells Elicits Potent Neutralizing Antibody and Protective Immunity Virology. Oct, 2009 | Pubmed ID: 19683779 Discovery of Diarylpyridine Derivatives As Novel Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Bioorganic & Medicinal Chemistry Letters. Sep, 2009 | Pubmed ID: 19666220 Combinations of the First and Next Generations of Human Immunodeficiency Virus (HIV) Fusion Inhibitors Exhibit a Highly Potent Synergistic Effect Against Enfuvirtide- Sensitive and -resistant HIV Type 1 Strains Journal of Virology. Aug, 2009 | Pubmed ID: 19493996 Drug-resistant Viruses May Repair Impaired Fitness by Mutations Outside the Drug Target Site Future Microbiology. Jun, 2009 | Pubmed ID: 19492961 Biochemical and Biophysical Research Communications. Jul, 2009 | Pubmed ID: 19463787 Phenotypic and Genotypic Characterization of Human Immunodeficiency Virus Type 1 CRF07_BC Strains Circulating in the Xinjiang Province of China Retrovirology. 2009 | Pubmed ID: 19442296 Antigenicity and Immunogenicity of SARS-CoV S Protein Receptor-binding Domain Stably Expressed in CHO Cells Biochemical and Biophysical Research Communications. Jul, 2009 | Pubmed ID: 19422787 Recombinant Ov-ASP-1, a Th1-biased Protein Adjuvant Derived from the Helminth Onchocerca Volvulus, Can Directly Bind and Activate Antigen-presenting Cells Journal of Immunology (Baltimore, Md. : 1950). Apr, 2009 | Pubmed ID: 19299698 Synergistic Efficacy of Combination of Enfuvirtide and Sifuvirtide, the First- and Next-generation HIV-fusion Inhibitors AIDS (London, England). Mar, 2009 | Pubmed ID: 19242316 The Spike Protein of SARS-CoV--a Target for Vaccine and Therapeutic Development Nature Reviews. Microbiology. Mar, 2009 | Pubmed ID: 19198616 Identification of Critical Antibody-binding Sites in the HIV-1 Gp41 Six-helix Bundle Core As Potential Targets for HIV-1 Fusion Inhibitors Immunobiology. 2009 | Pubmed ID: 19159827 Design, Synthesis, and Biological Evaluation of N-carboxyphenylpyrrole Derivatives As Potent HIV Fusion Inhibitors Targeting Gp41 Journal of Medicinal Chemistry. Dec, 2008 | Pubmed ID: 19053778 Development and Preclinical Studies of Broad-spectrum Anti-HIV Agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK) Journal of Medicinal Chemistry. Dec, 2008 | Pubmed ID: 19053755 Potent HIV Fusion Inhibitors Against Enfuvirtide-resistant HIV-1 Strains Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18852475 Conserved Salt Bridge Between the N- and C-terminal Heptad Repeat Regions of the Human Immunodeficiency Virus Type 1 Gp41 Core Structure is Critical for Virus Entry and Inhibition Journal of Virology. Nov, 2008 | Pubmed ID: 18768964 Deletion of Fusion Peptide or Destabilization of Fusion Core of HIV Gp41 Enhances Antigenicity and Immunogenicity of 4E10 Epitope Biochemical and Biophysical Research Communications. Nov, 2008 | Pubmed ID: 18762167 Novel Anti-HIV Peptides Containing Multiple Copies of Artificially Designed Heptad Repeat Motifs Biochemical and Biophysical Research Communications. Oct, 2008 | Pubmed ID: 18682248 Evaluation of Recombinant Onchocerca Volvulus Activation Associated Protein-1 (ASP-1) As a Potent Th1-biased Adjuvant with a Panel of Protein or Peptide-based Antigens and Commercial Inactivated Vaccines Vaccine. Sep, 2008 | Pubmed ID: 18675867 Rationally Designed Anti-HIV Peptides Containing Multifunctional Domains As Molecule Probes for Studying the Mechanisms of Action of the First and Second Generation HIV Fusion Inhibitors The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18662985 Prolongation of Corneal Xenotransplant Survival by T-cell Vaccination-induced T-regulatory Cells Xenotransplantation. May-Jun, 2008 | Pubmed ID: 18611224 Cross-reactive Human Immunodeficiency Virus Type 1-neutralizing Human Monoclonal Antibody That Recognizes a Novel Conformational Epitope on Gp41 and Lacks Reactivity Against Self-antigens Journal of Virology. Jul, 2008 | Pubmed ID: 18480433 Identification of a Critical Motif for the Human Immunodeficiency Virus Type 1 (HIV-1) Gp41 Core Structure: Implications for Designing Novel Anti-HIV Fusion Inhibitors Journal of Virology. Jul, 2008 | Pubmed ID: 18417584 Surface Exposure of the HIV-1 Env Cytoplasmic Tail LLP2 Domain During the Membrane Fusion Process: Interaction with Gp41 Fusion Core The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18408000 Interaction of HIV-1 Gp41 Core with NPF Motif in Epsin: Implication in Endocytosis of HIV The Journal of Biological Chemistry. May, 2008 | Pubmed ID: 18375383 Design and Evaluation of Sifuvirtide, a Novel HIV-1 Fusion Inhibitor The Journal of Biological Chemistry. Apr, 2008 | Pubmed ID: 18303020 Development of Subunit Vaccines Against Severe Acute Respiratory Syndrome Drugs of Today (Barcelona, Spain : 1998). Jan, 2008 | Pubmed ID: 18301805 Priming with RAAV Encoding RBD of SARS-CoV S Protein and Boosting with RBD-specific Peptides for T Cell Epitopes Elevated Humoral and Cellular Immune Responses Against SARS-CoV Infection Vaccine. Mar, 2008 | Pubmed ID: 18289745 Extracellular Matrix Protein Betaig-h3/TGFBI Promotes Metastasis of Colon Cancer by Enhancing Cell Extravasation Genes & Development. Feb, 2008 | Pubmed ID: 18245446 Molecular Modeling Studies of N-substituted Pyrrole Derivatives--potential HIV-1 Gp41 Inhibitors Bioorganic & Medicinal Chemistry. Mar, 2008 | Pubmed ID: 18226912 Intranasal Vaccination of Recombinant Adeno-associated Virus Encoding Receptor-binding Domain of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection Journal of Immunology (Baltimore, Md. : 1950). Jan, 2008 | Pubmed ID: 18178835 The Function of Coreceptor As a Basis for the Kinetic Dissection of HIV Type 1 Envelope Protein-mediated Cell Fusion FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2008 | Pubmed ID: 18032634 Potent Cross-reactive Neutralization of SARS Coronavirus Isolates by Human Monoclonal Antibodies Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17620608 Conserved Residue Lys574 in the Cavity of HIV-1 Gp41 Coiled-coil Domain is Critical for Six-helix Bundle Stability and Virus Entry The Journal of Biological Chemistry. Aug, 2007 | Pubmed ID: 17616522 Cleavage of Spike Protein of SARS Coronavirus by Protease Factor Xa is Associated with Viral Infectivity Biochemical and Biophysical Research Communications. Jul, 2007 | Pubmed ID: 17533109 Structure-based Identification of Small Molecule Compounds Targeting Cell Cyclophilin A with Anti-HIV-1 Activity European Journal of Pharmacology. Jun, 2007 | Pubmed ID: 17449029 Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the Gp41 Fusion Peptide Cell. Apr, 2007 | Pubmed ID: 17448989 HIV-1 Gp41 Ectodomain Enhances Cryptococcus Neoformans Binding to HBMEC Biochemical and Biophysical Research Communications. May, 2007 | Pubmed ID: 17400192 HIV Gp41 C-terminal Heptad Repeat Contains Multifunctional Domains. Relation to Mechanisms of Action of Anti-HIV Peptides The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17276993 HIV Entry Inhibitors Targeting Gp41: from Polypeptides to Small-molecule Compounds Current Pharmaceutical Design. 2007 | Pubmed ID: 17269924 The Mechanism by Which Molecules Containing the HIV Gp41 Core-binding Motif HXXNPF Inhibit HIV-1 Envelope Glycoprotein-mediated Syncytium Formation The Biochemical Journal. May, 2007 | Pubmed ID: 17223796 Identification of the HIV-1 Gp41 Core-binding Motif in the Scaffolding Domain of Caveolin-1 The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17197700 Polymorphisms of Type I Interferon Receptor 1 Promoter and Their Effects on Chronic Hepatitis B Virus Infection Journal of Hepatology. Feb, 2007 | Pubmed ID: 17125879 Receptor-binding Domain of SARS-CoV Spike Protein Induces Long-term Protective Immunity in an Animal Model Vaccine. Apr, 2007 | Pubmed ID: 17092615 Selection of a Novel Gp41-specific HIV-1 Neutralizing Human Antibody by Competitive Antigen Panning Journal of Immunological Methods. Dec, 2006 | Pubmed ID: 17078964 China Needs Safe and Effective Microbicides for Preventing Sexual Transmission of HIV The Lancet Infectious Diseases. Nov, 2006 | Pubmed ID: 17067914 Identification of the HIV-1 Gp41 Core-binding Motif--HXXNPF FEBS Letters. Sep, 2006 | Pubmed ID: 16904109 Microbicides: Stopping HIV at the Gate Lancet. Aug, 2006 | Pubmed ID: 16890813 Identification of a D-amino Acid Decapeptide HIV-1 Entry Inhibitor Biochemical and Biophysical Research Communications. Sep, 2006 | Pubmed ID: 16854380 Evaluation of "credit Card" Libraries for Inhibition of HIV-1 Gp41 Fusogenic Core Formation Journal of Combinatorial Chemistry. Jul-Aug, 2006 | Pubmed ID: 16827565 Recombinant Adeno-associated Virus Expressing the Receptor-binding Domain of Severe Acute Respiratory Syndrome Coronavirus S Protein Elicits Neutralizing Antibodies: Implication for Developing SARS Vaccines Virology. Sep, 2006 | Pubmed ID: 16793110 Antigenic and Immunogenic Characterization of Recombinant Baculovirus-expressed Severe Acute Respiratory Syndrome Coronavirus Spike Protein: Implication for Vaccine Design Journal of Virology. Jun, 2006 | Pubmed ID: 16731915 Identification and Characterization of Novel Neutralizing Epitopes in the Receptor-binding Domain of SARS-CoV Spike Protein: Revealing the Critical Antigenic Determinants in Inactivated SARS-CoV Vaccine Vaccine. Jun, 2006 | Pubmed ID: 16725238 Antigenic Properties of a Transport-competent Influenza HA/HIV Env Chimeric Protein Virology. Aug, 2006 | Pubmed ID: 16725170 Cellulose Acetate 1,2-benzenedicarboxylate Inhibits Infection by Cell-free and Cell-associated Primary HIV-1 Isolates AIDS Research and Human Retroviruses. May, 2006 | Pubmed ID: 16706617 Cross-neutralization of Human and Palm Civet Severe Acute Respiratory Syndrome Coronaviruses by Antibodies Targeting the Receptor-binding Domain of Spike Protein Journal of Immunology (Baltimore, Md. : 1950). May, 2006 | Pubmed ID: 16670317 Theta-defensins Prevent HIV-1 Env-mediated Fusion by Binding Gp41 and Blocking 6-helix Bundle Formation The Journal of Biological Chemistry. Jul, 2006 | Pubmed ID: 16648135 A Single Amino Acid Substitution (R441A) in the Receptor-binding Domain of SARS Coronavirus Spike Protein Disrupts the Antigenic Structure and Binding Activity Biochemical and Biophysical Research Communications. May, 2006 | Pubmed ID: 16615996 Antimicrobial Agents and Chemotherapy. Apr, 2006 | Pubmed ID: 16569857 The Ribosomal Protein L32-2 (RPL32-2) of S. Pombe Exhibits a Novel Extraribosomal Function by Acting As a Potential Transcriptional Regulator FEBS Letters. Mar, 2006 | Pubmed ID: 16516201 Neutralization of HIV-1 Primary Isolate by ELDKWA-specific Murine Monoclonal Antibodies Immunobiology. 2005 | Pubmed ID: 16323702 Identification of Immunodominant Epitopes on the Membrane Protein of the Severe Acute Respiratory Syndrome-associated Coronavirus Journal of Clinical Microbiology. Aug, 2005 | Pubmed ID: 16081901 Vaccine Design for Severe Acute Respiratory Syndrome Coronavirus Viral Immunology. 2005 | Pubmed ID: 16035944 SARS Vaccine Development Emerging Infectious Diseases. Jul, 2005 | Pubmed ID: 16022774 Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides As a New Class of HIV-1 Entry Inhibitors That Prevent Gp120 Binding to CD4 Virology. Sep, 2005 | Pubmed ID: 15996703 Chemoenzymatic Synthesis of HIV-1 Gp41 Glycopeptides: Effects of Glycosylation on the Anti-HIV Activity and Alpha-helix Bundle-forming Ability of Peptide C34 Chembiochem : a European Journal of Chemical Biology. Jun, 2005 | Pubmed ID: 15883971 Combination of Candidate Microbicides Cellulose Acetate 1,2-benzenedicarboxylate and UC781 Has Synergistic and Complementary Effects Against Human Immunodeficiency Virus Type 1 Infection Antimicrobial Agents and Chemotherapy. May, 2005 | Pubmed ID: 15855503 ROv-ASP-1, a Recombinant Secreted Protein of the Helminth Onchocercavolvulus, is a Potent Adjuvant for Inducing Antibodies to Ovalbumin, HIV-1 Polypeptide and SARS-CoV Peptide Antigens Vaccine. May, 2005 | Pubmed ID: 15837368 Theaflavin Derivatives in Black Tea and Catechin Derivatives in Green Tea Inhibit HIV-1 Entry by Targeting Gp41 Biochimica Et Biophysica Acta. May, 2005 | Pubmed ID: 15823507 Receptor-binding Domain of Severe Acute Respiratory Syndrome Coronavirus Spike Protein Contains Multiple Conformation-dependent Epitopes That Induce Highly Potent Neutralizing Antibodies Journal of Immunology (Baltimore, Md. : 1950). Apr, 2005 | Pubmed ID: 15814718 Identification of a Critical Neutralization Determinant of Severe Acute Respiratory Syndrome (SARS)-associated Coronavirus: Importance for Designing SARS Vaccines Virology. Mar, 2005 | Pubmed ID: 15749124 Different from the HIV Fusion Inhibitor C34, the Anti-HIV Drug Fuzeon (T-20) Inhibits HIV-1 Entry by Targeting Multiple Sites in Gp41 and Gp120 The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15640162 Inactivated SARS-CoV Vaccine Elicits High Titers of Spike Protein-specific Antibodies That Block Receptor Binding and Virus Entry Biochemical and Biophysical Research Communications. Dec, 2004 | Pubmed ID: 15530413 Mapping of Antigenic Sites on the Nucleocapsid Protein of the Severe Acute Respiratory Syndrome Coronavirus Journal of Clinical Microbiology. Nov, 2004 | Pubmed ID: 15528730 N-substituted Pyrrole Derivatives As Novel Human Immunodeficiency Virus Type 1 Entry Inhibitors That Interfere with the Gp41 Six-helix Bundle Formation and Block Virus Fusion Antimicrobial Agents and Chemotherapy. Nov, 2004 | Pubmed ID: 15504864 Receptor-binding Domain of SARS-CoV Spike Protein Induces Highly Potent Neutralizing Antibodies: Implication for Developing Subunit Vaccine Biochemical and Biophysical Research Communications. Nov, 2004 | Pubmed ID: 15474494 Identification of Immunodominant Sites on the Spike Protein of Severe Acute Respiratory Syndrome (SARS) Coronavirus: Implication for Developing SARS Diagnostics and Vaccines Journal of Immunology (Baltimore, Md. : 1950). Sep, 2004 | Pubmed ID: 15356154 High Throughput Screening and Characterization of HIV-1 Entry Inhibitors Targeting Gp41: Theories and Techniques Current Pharmaceutical Design. 2004 | Pubmed ID: 15180543 Organ Distribution of Severe Acute Respiratory Syndrome (SARS) Associated Coronavirus (SARS-CoV) in SARS Patients: Implications for Pathogenesis and Virus Transmission Pathways The Journal of Pathology. Jun, 2004 | Pubmed ID: 15141376 Interaction Between Heptad Repeat 1 and 2 Regions in Spike Protein of SARS-associated Coronavirus: Implications for Virus Fusogenic Mechanism and Identification of Fusion Inhibitors Lancet. Mar, 2004 | Pubmed ID: 15043961 Synthesis and Anti-HIV-1 Activity of 4-[4-(4,6-bisphenylamino-triazin-2-ylamino)-5-methoxy-2-methylphenylazo]-5-hydroxynaphthalene-2,7-disulfonic Acid and Its Derivatives Bioorganic & Medicinal Chemistry. Mar, 2004 | Pubmed ID: 14980633 Binding of the 2F5 Monoclonal Antibody to Native and Fusion-intermediate Forms of Human Immunodeficiency Virus Type 1 Gp41: Implications for Fusion-inducing Conformational Changes Journal of Virology. Mar, 2004 | Pubmed ID: 14963170 Rapid and Automated Fluorescence-linked Immunosorbent Assay for High-throughput Screening of HIV-1 Fusion Inhibitors Targeting Gp41 Journal of Biomolecular Screening. Dec, 2003 | Pubmed ID: 14711394 Determination of the HIV-1 Gp41 Fusogenic Core Conformation Modeled by Synthetic Peptides: Applicable for Identification of HIV-1 Fusion Inhibitors Peptides. Sep, 2003 | Pubmed ID: 14706544 Development of a Cell-based Enzyme-linked Immunosorbent Assay for High-throughput Screening of HIV Type 1 Entry Inhibitors Targeting the Coreceptor CXCR4 AIDS Research and Human Retroviruses. Nov, 2003 | Pubmed ID: 14678601 Role of the Fusion Peptide and Membrane-proximal Domain in HIV-1 Envelope Glycoprotein-mediated Membrane Fusion Biochemistry. Dec, 2003 | Pubmed ID: 14640682 Automatic Quantitation of HIV-1 Mediated Cell-to-cell Fusion with a Digital Image Analysis System (DIAS): Application for Rapid Screening of HIV-1 Fusion Inhibitors Journal of Virological Methods. Feb, 2003 | Pubmed ID: 12505629 Design of a Protein Surface Antagonist Based on Alpha-helix Mimicry: Inhibition of Gp41 Assembly and Viral Fusion Angewandte Chemie (International Ed. in English). Jan, 2002 | Pubmed ID: 12491408 The in Vitro and in Vivo Protective Activity of Monoclonal Antibodies Directed Against Hantaan Virus: Potential Application for Immunotherapy and Passive Immunization Biochemical and Biophysical Research Communications. Nov, 2002 | Pubmed ID: 12408987 XTT Formazan Widely Used to Detect Cell Viability Inhibits HIV Type 1 Infection in Vitro by Targeting Gp41 AIDS Research and Human Retroviruses. Sep, 2002 | Pubmed ID: 12396451 Identification of Inhibitors of the HIV-1 Gp41 Six-helix Bundle Formation from Extracts of Chinese Medicinal Herbs Prunella Vulgaris and Rhizoma Cibotte Life Sciences. Aug, 2002 | Pubmed ID: 12151056 Anti-HIV-1 Activity of Cellulose Acetate Phthalate: Synergy with Soluble CD4 and Induction of "dead-end" Gp41 Six-helix Bundles BMC Infectious Diseases. Apr, 2002 | Pubmed ID: 11983022 Peptide and Non-peptide HIV Fusion Inhibitors Current Pharmaceutical Design. 2002 | Pubmed ID: 11945159 פרוטוקול רקומביננטי מזוכך מבוססי חיסונים הסארס: הכנת חלבון, חיסון בעלי חיים איתור נטרול Lanying Du1, Xiujuan Zhang1, Jixiang Liu1, Shibo Jiang1 1Lindsley F. Kimball Research Institute, New York Blood Center JoVE 2444 Immunology and Infection
פרוטוקול רקומביננטי מזוכך מבוססי חיסונים הסארס: הכנת חלבון, חיסון בעלי חיים איתור נטרול Lanying Du1, Xiujuan Zhang1, Jixiang Liu1, Shibo Jiang1 1Lindsley F. Kimball Research Institute, New York Blood Center JoVE 2444 Immunology and Infection
