Shih-Heng Chen Neurobiology Laboratory National Institute of Environmental Health Sciences Biography Publications Institution JoVE Articles Shih-Heng Chen has not added a biography. If you are Shih-Heng Chen and would like to personalize this page please email our Author Liaison for assistance. Publications Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons As They Mature Drug Metabolism and Disposition: the Biological Fate of Chemicals. 06, 2018 | Pubmed ID: 29626075 Physiological Concentration of Prostaglandin E Exerts Anti-inflammatory Effects by Inhibiting Microglial Production of Superoxide Through a Novel Pathway Molecular Neurobiology. Oct, 2018 | Pubmed ID: 29492849 En Masse Lentiviral Gene Delivery to Mouse Fertilized Eggs Via Laser Perforation of Zona Pellucida Transgenic Research. 02, 2018 | Pubmed ID: 29442214 Clozapine Metabolites Protect Dopaminergic Neurons Through Inhibition of Microglial NADPH Oxidase Journal of Neuroinflammation. 05, 2016 | Pubmed ID: 27184631 Neurons and Astroglia Govern Microglial Endotoxin Tolerance Through Macrophage Colony-stimulating Factor Receptor-mediated ERK1/2 Signals Brain, Behavior, and Immunity. 07, 2016 | Pubmed ID: 27132056 Critical Role of the Mac1/NOX2 Pathway in Mediating Reactive Microgliosis-generated Chronic Neuroinflammation and Progressive Neurodegeneration Current Opinion in Pharmacology. Feb, 2016 | Pubmed ID: 26498406 A Novel Role of Microglial NADPH Oxidase in Mediating Extra-synaptic Function of Norepinephrine in Regulating Brain Immune Homeostasis Glia. Jun, 2015 | Pubmed ID: 25740080 Post-treatment with an Ultra-low Dose of NADPH Oxidase Inhibitor Diphenyleneiodonium Attenuates Disease Progression in Multiple Parkinson's Disease Models Brain : a Journal of Neurology. May, 2015 | Pubmed ID: 25716193 The BDNF Val66Met Polymorphism and Plasma Brain-derived Neurotrophic Factor Levels in Han Chinese Heroin-dependent Patients Scientific Reports. Feb, 2015 | Pubmed ID: 25640280 PGE2 Inhibits IL-10 Production Via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition Molecular Neurobiology. Aug, 2015 | Pubmed ID: 25218510 Microglial Regulation of Immunological and Neuroprotective Functions of Astroglia Glia. Jan, 2015 | Pubmed ID: 25130274 Substance P Exacerbates Dopaminergic Neurodegeneration Through Neurokinin-1 Receptor-independent Activation of Microglial NADPH Oxidase The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2014 | Pubmed ID: 25209287 Subpicomolar Diphenyleneiodonium Inhibits Microglial NADPH Oxidase with High Specificity and Shows Great Potential As a Therapeutic Agent for Neurodegenerative Diseases Glia. Dec, 2014 | Pubmed ID: 25043383 Inducible Nitric Oxide Synthase is Key to Peroxynitrite-mediated, LPS-induced Protein Radical Formation in Murine Microglial BV2 Cells Free Radical Biology & Medicine. Aug, 2014 | Pubmed ID: 24746617 The BDNF Val66Met Polymorphism and Plasma Brain-derived Neurotrophic Factor Levels in Han Chinese Patients with Bipolar Disorder and Schizophrenia Progress in Neuro-psychopharmacology & Biological Psychiatry. Jun, 2014 | Pubmed ID: 24468644 Preparation of Rodent Primary Cultures for Neuron-glia, Mixed Glia, Enriched Microglia, and Reconstituted Cultures with Microglia Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23813383 Inflammation in Patients with Schizophrenia: the Therapeutic Benefits of Risperidone Plus Add-on Dextromethorphan Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Sep, 2012 | Pubmed ID: 22730040 Naloxone Inhibits Immune Cell Function by Suppressing Superoxide Production Through a Direct Interaction with Gp91phox Subunit of NADPH Oxidase Journal of Neuroinflammation. Feb, 2012 | Pubmed ID: 22340895 Low-dose Memantine Attenuated Morphine Addictive Behavior Through Its Anti-inflammation and Neurotrophic Effects in Rats Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Jun, 2012 | Pubmed ID: 22205542 Rotenone Activates Phagocyte NADPH Oxidase by Binding to Its Membrane Subunit Gp91phox Free Radical Biology & Medicine. Jan, 2012 | Pubmed ID: 22094225 Amantadine Protects Dopamine Neurons by a Dual Action: Reducing Activation of Microglia and Inducing Expression of GDNF in Astroglia [corrected] Neuropharmacology. Sep, 2011 | Pubmed ID: 21586298 β2-adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia Via a Novel Signaling Pathway Journal of Immunology (Baltimore, Md. : 1950). Apr, 2011 | Pubmed ID: 21335487 Microglial MAC1 Receptor and PI3K Are Essential in Mediating β-amyloid Peptide-induced Microglial Activation and Subsequent Neurotoxicity Journal of Neuroinflammation. Jan, 2011 | Pubmed ID: 21232086 Verapamil Protects Dopaminergic Neuron Damage Through a Novel Anti-inflammatory Mechanism by Inhibition of Microglial Activation Neuropharmacology. Feb-Mar, 2011 | Pubmed ID: 20950631 Fare Lentiviral Gene lazer destekli teslim yumurta döllenmiş Negin P. Martin*1, Page Myers*2, Eugenia Goulding1, Shih-Heng Chen1, Mitzie Walker1, Thomas M. Porter1, Lucas Van Gorder1, Amanda Mathew1, Artiom Gruzdev3, Erica Scappini4, Charles Romeo1 1Neurobiology Laboratory, National Institute of Environmental Health Sciences, 2Comparative Medicine Branch, National Institute of Environmental Health Sciences, 3Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, 4Signal Transduction Laboratory, National Institute of Environmental Health Sciences JoVE 58327 Biology
Fare Lentiviral Gene lazer destekli teslim yumurta döllenmiş Negin P. Martin*1, Page Myers*2, Eugenia Goulding1, Shih-Heng Chen1, Mitzie Walker1, Thomas M. Porter1, Lucas Van Gorder1, Amanda Mathew1, Artiom Gruzdev3, Erica Scappini4, Charles Romeo1 1Neurobiology Laboratory, National Institute of Environmental Health Sciences, 2Comparative Medicine Branch, National Institute of Environmental Health Sciences, 3Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, 4Signal Transduction Laboratory, National Institute of Environmental Health Sciences JoVE 58327 Biology