Shioko Kimura National Cancer Institute, Laboratory of Metabolism National Institutes of Health Biography Publications Institution JoVE Articles Shioko Kimura has not added a biography. If you are Shioko Kimura and would like to personalize this page please email our Author Liaison for assistance. Publications Transgenically-expressed Secretoglobin 3A2 Accelerates Resolution of Bleomycin-induced Pulmonary Fibrosis in Mice BMC Pulmonary Medicine. 2015 | Pubmed ID: 26178733 KRAS(G12D)-mediated Oncogenic Transformation of Thyroid Follicular Cells Requires Long-term TSH Stimulation and is Regulated by SPRY1 Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2015 | Pubmed ID: 26146959 Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans Gastroenterology. Oct, 2015 | Pubmed ID: 26099526 SCGB3A2 Inhibits Acrolein-Induced Apoptosis Through Decreased P53 Phosphorylation Acta Histochemica Et Cytochemica. Apr, 2015 | Pubmed ID: 26019375 Expression of Stanniocalcin 1 in Thyroid Side Population Cells and Thyroid Cancer Cells Thyroid : Official Journal of the American Thyroid Association. Apr, 2015 | Pubmed ID: 25647164 Activation of Intestinal Human Pregnane X Receptor Protects Against Azoxymethane/dextran Sulfate Sodium-induced Colon Cancer The Journal of Pharmacology and Experimental Therapeutics. Dec, 2014 | Pubmed ID: 25277138 Secretoglobin Superfamily Protein SCGB3A2 Deficiency Potentiates Ovalbumin-induced Allergic Pulmonary Inflammation Mediators of Inflammation. 2014 | Pubmed ID: 25242865 Thyroid Regeneration: How Stem Cells Play a Role? Frontiers in Endocrinology. 2014 | Pubmed ID: 24782833 Regulation of LH/FSH Expression by Secretoglobin 3A2 in the Mouse Pituitary Gland Cell and Tissue Research. Apr, 2014 | Pubmed ID: 24514953 Molecular Cloning and Functional Characterization of Two Forms of Pax8 in the Rainbow Trout, Oncorhynchus Mykiss General and Comparative Endocrinology. Mar, 2014 | Pubmed ID: 24380675 Preclinical Evaluation of Human Secretoglobin 3A2 in Mouse Models of Lung Development and Fibrosis American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2014 | Pubmed ID: 24213919 Stem Cell Antigen 1-positive Mesenchymal Cells Are the Origin of Follicular Cells During Thyroid Regeneration PloS One. 2013 | Pubmed ID: 24278321 Postnatal Expression of BRAFV600E Does Not Induce Thyroid Cancer in Mouse Models of Thyroid Papillary Carcinoma Endocrinology. Nov, 2013 | Pubmed ID: 23970782 Noninvasive Monitoring of Pulmonary Fibrosis by Targeting Matrix Metalloproteinases (MMPs) Molecular Pharmaceutics. Jun, 2013 | Pubmed ID: 23607644 Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma Molecular Cell. Apr, 2013 | Pubmed ID: 23523371 Deficiency of CCAAT/enhancer Binding Protein Family DNA Binding Prevents Malignant Conversion of Adenoma to Carcinoma in NNK-induced Lung Carcinogenesis in the Mouse Molecular Cancer. 2012 | Pubmed ID: 23234329 Neuroepithelial Body Microenvironment is a Niche for a Distinct Subset of Clara-like Precursors in the Developing Airways Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22797898 Soluble Vascular Adhesion Protein-1 Accumulates in Proliferative Diabetic Retinopathy Investigative Ophthalmology & Visual Science. Jun, 2012 | Pubmed ID: 22618595 Thyroid Regeneration: Characterization of Clear Cells After Partial Thyroidectomy Endocrinology. May, 2012 | Pubmed ID: 22454152 Thyroid-specific Knockout of the Tumor Suppressor Mitogen-inducible Gene 6 Activates Epidermal Growth Factor Receptor Signaling Pathways and Suppresses Nuclear Factor-κB Activity Surgery. Dec, 2011 | Pubmed ID: 22136853 The Integrity of Cholinergic Basal Forebrain Neurons Depends on Expression of Nkx2-1 The European Journal of Neuroscience. Dec, 2011 | Pubmed ID: 22098391 Conditional Deletion of Insulin Receptor in Thyrocytes Does Not Affect Thyroid Structure and Function Endocrine Journal. 2011 | Pubmed ID: 21908931 Wnt/β-catenin Signaling Pathway is a Direct Enhancer of Thyroid Transcription Factor-1 in Human Papillary Thyroid Carcinoma Cells PloS One. 2011 | Pubmed ID: 21814573 Thyroid-specific Transcription Factors and Their Roles in Thyroid Cancer Journal of Thyroid Research. 2011 | Pubmed ID: 21687604 Experience Dictates Stem Cell Fate in the Adult Hippocampus Neuron. Jun, 2011 | Pubmed ID: 21658584 Secretoglobin 3A2 Suppresses Bleomycin-induced Pulmonary Fibrosis by Transforming Growth Factor Beta Signaling Down-regulation The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21478551 FOXA1 Plays a Role in Regulating Secretoglobin 1a1 Expression in the Absence of CCAAT/enhancer Binding Protein Activities in Lung in Vivo American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2011 | Pubmed ID: 21224212 Thyrotrophin Receptor Signaling Dependence of Braf-induced Thyroid Tumor Initiation in Mice Proceedings of the National Academy of Sciences of the United States of America. Jan, 2011 | Pubmed ID: 21220306 Development of Thyroid Gland and Ultimobranchial Body Cyst is Independent of P63 Laboratory Investigation; a Journal of Technical Methods and Pathology. Jan, 2011 | Pubmed ID: 20697379 Secretoglobin 3A2/uteroglobin-related Protein 1 is a Novel Marker for Pulmonary Carcinoma in Mice and Humans Lung Cancer (Amsterdam, Netherlands). Jan, 2011 | Pubmed ID: 20466451 A Functional Interaction Between CPI-17 and RACK1 Proteins in Bronchial Smooth Muscle Cells Biochemical and Biophysical Research Communications. Oct, 2010 | Pubmed ID: 20875397 Identification and Characterization of Rat RhoA Gene Promoter Journal of Pharmacological Sciences. 2010 | Pubmed ID: 20308800 The Progenitor Zone of the Ventral Medial Ganglionic Eminence Requires Nkx2-1 to Generate Most of the Globus Pallidus but Few Neocortical Interneurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2010 | Pubmed ID: 20181579 The Proximal STAT6 and NF-kappaB Sites Are Responsible for IL-13- and TNF-alpha-induced RhoA Transcriptions in Human Bronchial Smooth Muscle Cells Pharmacological Research. May, 2010 | Pubmed ID: 20006706 Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced Thyroid Adenoma in Mice Carcinogenesis. Sep, 2009 | Pubmed ID: 19581346 IFN-gamma Down-regulates Secretoglobin 3A1 Gene Expression Biochemical and Biophysical Research Communications. Feb, 2009 | Pubmed ID: 19135978 Oncostatin M Regulates Secretoglobin 3A1 and 3A2 Expression in a Bidirectional Manner American Journal of Respiratory Cell and Molecular Biology. May, 2009 | Pubmed ID: 18978304 Expression of Secretoglobin3A2 (SCGB3A2) in Primary Pulmonary Carcinomas Fukushima Journal of Medical Science. Dec, 2008 | Pubmed ID: 19418968 Postmitotic Nkx2-1 Controls the Migration of Telencephalic Interneurons by Direct Repression of Guidance Receptors Neuron. Sep, 2008 | Pubmed ID: 18786357 The Requirement of Nkx2-1 in the Temporal Specification of Cortical Interneuron Subtypes Neuron. Sep, 2008 | Pubmed ID: 18786356 CAATT/enhancer-binding Proteins Alpha and Delta Interact with NKX2-1 to Synergistically Activate Mouse Secretoglobin 3A2 Gene Expression The Journal of Biological Chemistry. Sep, 2008 | Pubmed ID: 18632661 Role of Secretoglobin 3A2 in Lung Development American Journal of Respiratory and Critical Care Medicine. Aug, 2008 | Pubmed ID: 18535256 Regulation of Mouse Scgb3a1 Gene Expression by NF-Y and Association of CpG Methylation with Its Tissue-specific Expression BMC Molecular Biology. 2008 | Pubmed ID: 18194566 Plasma UGRP1 Levels Associate with Promoter G-112A Polymorphism and the Severity of Asthma Allergology International : Official Journal of the Japanese Society of Allergology. Mar, 2008 | Pubmed ID: 18089940 Side Population Cells in the Mouse Thyroid Exhibit Stem/progenitor Cell-like Characteristics Endocrinology. Sep, 2007 | Pubmed ID: 17584961 Pten Loss in the Mouse Thyroid Causes Goiter and Follicular Adenomas: Insights into Thyroid Function and Cowden Disease Pathogenesis Cancer Research. Feb, 2007 | Pubmed ID: 17283127 A Comprehensive Investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach Chemical Research in Toxicology. Mar, 2007 | Pubmed ID: 17279779 GATA and Nkx Factors Synergistically Regulate Tissue-specific Gene Expression and Development in Vivo Development (Cambridge, England). Jan, 2007 | Pubmed ID: 17164424 Deletion of the Ttf1 Gene in Differentiated Neurons Disrupts Female Reproduction Without Impairing Basal Ganglia Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2006 | Pubmed ID: 17182767 Identification and Expression of Alternative Splice Variants of the Mouse Ppp1r3b Gene in Lung Epithelial Cells Biochemical and Biophysical Research Communications. Oct, 2006 | Pubmed ID: 16949035 Peroxisome Proliferator-activated Receptor Alpha Activation During Pregnancy Severely Impairs Mammary Lobuloalveolar Development in Mice Endocrinology. Oct, 2006 | Pubmed ID: 16857745 Regulation of Mouse Hepatic Alpha-amino-beta-carboxymuconate-epsilon-semialdehyde Decarboxylase, a Key Enzyme in the Tryptophan-nicotinamide Adenine Dinucleotide Pathway, by Hepatocyte Nuclear Factor 4alpha and Peroxisome Proliferator-activated Receptor Alpha Molecular Pharmacology. Oct, 2006 | Pubmed ID: 16807375 Thyroid-specific Enhancer-binding Protein/NKX2.1 is Required for the Maintenance of Ordered Architecture and Function of the Differentiated Thyroid Molecular Endocrinology (Baltimore, Md.). Aug, 2006 | Pubmed ID: 16601074 Hop Functions Downstream of Nkx2.1 and GATA6 to Mediate HDAC-dependent Negative Regulation of Pulmonary Gene Expression American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2006 | Pubmed ID: 16510470 A Common Regulatory Region Functions Bidirectionally in Transcriptional Activation of the Human CYP1A1 and CYP1A2 Genes Molecular Pharmacology. Jun, 2006 | Pubmed ID: 16505155 Uteroglobin-related Protein 1 Expression Suppresses Allergic Airway Inflammation in Mice American Journal of Respiratory and Critical Care Medicine. May, 2006 | Pubmed ID: 16456148 Alterations in Skin and Stratified Epithelia by Constitutively Activated PPARalpha The Journal of Investigative Dermatology. Feb, 2006 | Pubmed ID: 16374467 Origin of the Ultimobranchial Body Cyst: T/ebp/Nkx2.1 Expression is Required for Development and Fusion of the Ultimobranchial Body to the Thyroid Developmental Dynamics : an Official Publication of the American Association of Anatomists. May, 2006 | Pubmed ID: 16342117 Directed Differentiation of Neural Cells to Hypothalamic Dopaminergic Neurons Development (Cambridge, England). Dec, 2005 | Pubmed ID: 16284116 Induction of Uteroglobin-related Protein 2 (Ugrp2) Gene Expression by the Th2 Cytokines IL-4 and IL-13 Journal of Immunology (Baltimore, Md. : 1950). Nov, 2005 | Pubmed ID: 16237061 Differential Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Mice Humanized for CYP1A1 and CYP1A2 Chemical Research in Toxicology. Sep, 2005 | Pubmed ID: 16167840 A Mouse Model Demonstrates a Multigenic Origin of Congenital Hypothyroidism Endocrinology. Dec, 2005 | Pubmed ID: 16150900 Ventromedial Hypothalamic Nucleus-specific Enhancer of Ad4BP/SF-1 Gene Molecular Endocrinology (Baltimore, Md.). Nov, 2005 | Pubmed ID: 15994202 Induction of Uteroglobin-related Protein 2 (Ugrp2) Expression by EGF and TGFalpha FEBS Letters. Apr, 2005 | Pubmed ID: 15811345 Interleukin-5 Reduces the Expression of Uteroglobin-related Protein (UGRP) 1 Gene in Allergic Airway Inflammation Immunology Letters. Feb, 2005 | Pubmed ID: 15626484 An Integrated Regulatory Network Controlling Survival and Migration in Thyroid Organogenesis Developmental Biology. Dec, 2004 | Pubmed ID: 15581879 Progressive Glomerulonephritis and Histiocytic Sarcoma Associated with Macrophage Functional Defects in CYP1B1-deficient Mice Toxicologic Pathology. Nov-Dec, 2004 | Pubmed ID: 15580705 Decreased Expression of Uteroglobin-related Protein 1 in Inflamed Mouse Airways is Mediated by IL-9 American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2004 | Pubmed ID: 15531759 Interleukin-10 Induces Uteroglobin-related Protein (UGRP) 1 Gene Expression in Lung Epithelial Cells Through Homeodomain Transcription Factor T/EBP/NKX2.1 The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15485815 Developmental Regulation of Claudin Localization by Fetal Alveolar Epithelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2004 | Pubmed ID: 15347569 Thyrocyte-specific Expression of Cre Recombinase in Transgenic Mice Genesis (New York, N.Y. : 2000). Jul, 2004 | Pubmed ID: 15282748 In Vivo Characterization of the Nkx2.1 Promoter/enhancer Elements in Transgenic Mice Gene. Apr, 2004 | Pubmed ID: 15094193 [Homeodomain Transcription Factor T/EBP/NKX2.1 in Development and Differentiation of the Thyroid and Lung] Seikagaku. The Journal of Japanese Biochemical Society. Dec, 2003 | Pubmed ID: 14748143 Hypothyroidism in Thyroid Transcription Factor 1 Haploinsufficiency is Caused by Reduced Expression of the Thyroid-stimulating Hormone Receptor Molecular Endocrinology (Baltimore, Md.). Nov, 2003 | Pubmed ID: 12907760 Aberrant Trajectory of Ascending Dopaminergic Pathway in Mice Lacking Nkx2.1 Experimental Neurology. Jul, 2003 | Pubmed ID: 12821380 Microarray Analysis Using Amplified MRNA from Laser Capture Microdissection of Microscopic Hepatocellular Precancerous Lesions and Frozen Hepatocellular Carcinomas Reveals Unique and Consistent Gene Expression Profiles Toxicologic Pathology. May-Jun, 2003 | Pubmed ID: 12746117 Carcinogenesis of the Food Mutagen PhIP in Mice is Independent of CYP1A2 Carcinogenesis. Mar, 2003 | Pubmed ID: 12663521 Study of P450 Function Using Gene Knockout and Transgenic Mice Archives of Biochemistry and Biophysics. Jan, 2003 | Pubmed ID: 12464254 Pituitary Hormones Are Not Required for Sexual Differentiation of Male Mice: Phenotype of the T/ebp/Nkx2.1 Null Mutant Mice Endocrinology. Nov, 2002 | Pubmed ID: 12399445 Partial Deficiency of Thyroid Transcription Factor 1 Produces Predominantly Neurological Defects in Humans and Mice The Journal of Clinical Investigation. Feb, 2002 | Pubmed ID: 11854318 Increased Expression of Thyroid Transcription Factor-1 (TTF-1) in Respiratory Epithelial Cells Inhibits Alveolarization and Causes Pulmonary Inflammation Developmental Biology. Feb, 2002 | Pubmed ID: 11820807 A Polymorphism in the Human UGRP1 Gene Promoter That Regulates Transcription is Associated with an Increased Risk of Asthma American Journal of Human Genetics. Mar, 2002 | Pubmed ID: 11813133 एक साधारण उपकरण तेजी से माउस आंत के पूरे mounts तैयार करने के लिए Mitsuhiro Yoneda1, Alfredo A. Molinolo2, Jerrold M. Ward3, Shioko Kimura1, Robert A. Goodlad4 1National Cancer Institute, Laboratory of Metabolism, National Institutes of Health, 2National Institute of Dental and Craniofacial Research, Oral and Pharyngeal Cancer Branch, National Institutes of Health, 3Global VetPathology, 4Centre for Pathology, Hammersmith Hospital, Imperial College Medicine अवेध्य intratracheal इंटुबैषेण माउस फेफड़ों के रोग विज्ञान और शरीर विज्ञान का अध्ययन करने के लिए Yan Cai1, Shioko Kimura1 1Laboratory of Metabolism, National Cancer Institute, National Institutes of Health JoVE 50601 Medicine
एक साधारण उपकरण तेजी से माउस आंत के पूरे mounts तैयार करने के लिए Mitsuhiro Yoneda1, Alfredo A. Molinolo2, Jerrold M. Ward3, Shioko Kimura1, Robert A. Goodlad4 1National Cancer Institute, Laboratory of Metabolism, National Institutes of Health, 2National Institute of Dental and Craniofacial Research, Oral and Pharyngeal Cancer Branch, National Institutes of Health, 3Global VetPathology, 4Centre for Pathology, Hammersmith Hospital, Imperial College Medicine
अवेध्य intratracheal इंटुबैषेण माउस फेफड़ों के रोग विज्ञान और शरीर विज्ञान का अध्ययन करने के लिए Yan Cai1, Shioko Kimura1 1Laboratory of Metabolism, National Cancer Institute, National Institutes of Health JoVE 50601 Medicine
