Shishir Shetty National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy University of Birmingham Biography Publications Institution JoVE Articles Shishir Shetty has not added a biography. If you are Shishir Shetty and would like to personalize this page please email our Author Liaison for assistance. Publications Scavenger Receptors: Novel Roles in the Pathogenesis of Liver Inflammation and Cancer Seminars in Liver Disease. Sep, 2021 | Pubmed ID: 34553345 Editorial: Overcoming the Immune Microenvironment of Hepatocellular Cancer Frontiers in Immunology. 2021 | Pubmed ID: 34149741 Systemic Blockade of Clever-1 Elicits Lymphocyte Activation Alongside Checkpoint Molecule Downregulation in Patients with Solid Tumors: Results from a Phase I/II Clinical Trial Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2021 | Pubmed ID: 34078651 Prognostic Value and Potential Immunoregulatory Role of SCARF1 in Hepatocellular Carcinoma Frontiers in Oncology. 2020 | Pubmed ID: 34354939 The Role of Sinusoidal Endothelial Cells in the Axis of Inflammation and Cancer Within the Liver Frontiers in Physiology. 2020 | Pubmed ID: 32982772 Hypothermic Oxygenated Liver Perfusion (HOPE) Prevents Tumor Recurrence in Liver Transplantation From Donation After Circulatory Death Annals of Surgery. 11, 2020 | Pubmed ID: 32889870 Hepatocellular Carcinoma Demonstrates Heterogeneous Growth Patterns in a Multicenter Cohort of Patients With Cirrhosis Hepatology (Baltimore, Md.). 11, 2020 | Pubmed ID: 32017165 Multidisciplinary Team Management of Carcinoid Heart Disease Endocrine Connections. Dec, 2019 | Pubmed ID: 31751305 Fenestral Diaphragms and PLVAP Associations in Liver Sinusoidal Endothelial Cells Are Developmentally Regulated Scientific Reports. 10, 2019 | Pubmed ID: 31666588 Bile Acid Metabolism and T Cell Responses in Cholangiopathy: Not One-way Traffic Journal of Hepatology. 10, 2019 | Pubmed ID: 31447221 The Role of Stabilin-1 in Lymphocyte Trafficking and Macrophage Scavenging in the Liver Microenvironment Biomolecules. 07, 2019 | Pubmed ID: 31315308 Tumour-associated Macrophages in Hepatocellular Carcinoma: Pressing the Metabolic Switch to Prevent T Cell Responses Journal of Hepatology. 08, 2019 | Pubmed ID: 31208893 Clinical Implications of Heterogeneity in PD-L1 Immunohistochemical Detection in Hepatocellular Carcinoma: the Blueprint-HCC Study British Journal of Cancer. 05, 2019 | Pubmed ID: 31061454 Erratum: Novel Targets in the Immune Microenvironment of the Hepatic Sinusoids for Treating Liver Diseases Seminars in Liver Disease. 05, 2019 | Pubmed ID: 30991424 Novel Targets in the Immune Microenvironment of the Hepatic Sinusoids for Treating Liver Diseases Seminars in Liver Disease. May, 2019 | Pubmed ID: 30912097 More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking Frontiers in Immunology. 2018 | Pubmed ID: 30631321 Carcinogenesis on the Background of Liver Fibrosis: Implications for the Management of Hepatocellular Cancer World Journal of Gastroenterology. Oct, 2018 | Pubmed ID: 30357021 Liver Sinusoidal Endothelial Cells - Gatekeepers of Hepatic Immunity Nature Reviews. Gastroenterology & Hepatology. 09, 2018 | Pubmed ID: 29844586 Chronic Liver Disease: Scavenger Hunt for Novel Therapies Lancet (London, England). 01, 2018 | Pubmed ID: 29353605 SCARF-1 Promotes Adhesion of CD4 T Cells to Human Hepatic Sinusoidal Endothelium Under Conditions of Shear Stress Scientific Reports. 12, 2017 | Pubmed ID: 29242513 CD151 Supports VCAM-1-mediated Lymphocyte Adhesion to Liver Endothelium and is Upregulated in Chronic Liver Disease and Hepatocellular Carcinoma American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2017 | Pubmed ID: 28473332 Human Liver Sinusoidal Endothelial Cells Promote Intracellular Crawling of Lymphocytes During Recruitment: A New Step in Migration Hepatology (Baltimore, Md.). 01, 2017 | Pubmed ID: 27770554 Comparing Clinical Presentations, Treatments and Outcomes of Hepatocellular Carcinoma Due to Hepatitis C and Non-alcoholic Fatty Liver Disease QJM : Monthly Journal of the Association of Physicians. Feb, 2017 | Pubmed ID: 27634970 NOTCH1 Mediates a Switch Between Two Distinct Secretomes During Senescence Nature Cell Biology. 09, 2016 | Pubmed ID: 27525720 Stabilin-1 Expression Defines a Subset of Macrophages That Mediate Tissue Homeostasis and Prevent Fibrosis in Chronic Liver Injury Proceedings of the National Academy of Sciences of the United States of America. 08, 2016 | Pubmed ID: 27474165 Enamel Remineralization Assessment After Treatment with Three Different Remineralizing Agents Using Surface Microhardness: An in Vitro Study Journal of Conservative Dentistry : JCD. Jan, 2014 | Pubmed ID: 24554861 Neoadjuvant Bronchoscopic Intervention: Bridge to Lung Parenchyma Sparing Surgery Journal of Cancer Research and Therapeutics. Oct-Dec, 2013 | Pubmed ID: 24518744 Salivary Ascorbic Acid Levels in Betel Quid Chewers: A Biochemical Study South Asian Journal of Cancer. Jul, 2013 | Pubmed ID: 24455594 Multiple Trichoepitheliomas: A Rare Occurrence South Asian Journal of Cancer. Apr, 2013 | Pubmed ID: 24455549 Leiomyosarcoma of Cervix Journal of Obstetrics and Gynaecology of India. Jun, 2013 | Pubmed ID: 24431642 Comparative Evaluation of Bactericidal Effects on Enterococcus Faecalis Using Diode Laser Irradiation, Sodium Hypochlorite and Chlorhexidine Gluconate Irrigation"- an In Vitro Study Oral Health and Dental Management. Sep, 2013 | Pubmed ID: 24352305 Multiple Impacted Second Molars: a Rare Radiographic Finding General Dentistry. Mar-Apr, 2013 | Pubmed ID: 23454327 Estimation of Serum Malondialdehyde in Potentially Malignant Disorders and Post-antioxidant Treated Patients: A Biochemical Study Contemporary Clinical Dentistry. Oct, 2012 | Pubmed ID: 23633807 Evaluation of Micronutrient Status in Serum and Saliva of Oral Submucous Fibrosis Patients: A Clinicopathological Study Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology. Oct, 2012 | Pubmed ID: 23580824 The Reverse Claw: Report of an Extremely Rare Facial Talon Cusp Dental Research Journal. Sep, 2012 | Pubmed ID: 23559933 Co-occurrence of Intraoral Hemangioma and Port Wine Stain: A Rare Case Indian Dermatology Online Journal. Jan, 2012 | Pubmed ID: 23130257 Post-transplant Liver Biopsy and the Immune Response: Lessons for the Clinician Expert Review of Clinical Immunology. Sep, 2012 | Pubmed ID: 23078062 Drug Induced Xerostomia in Elderly Individuals: An Institutional Study Contemporary Clinical Dentistry. Apr, 2012 | Pubmed ID: 22919217 Oral Malignant Melanoma--an Unusual Presentation Gerodontology. Jun, 2012 | Pubmed ID: 22612841 Ectopic Pleomorphic Adenoma North American Journal of Medical Sciences. Apr, 2012 | Pubmed ID: 22536563 Recruitment Mechanisms of Primary and Malignant B Cells to the Human Liver Hepatology (Baltimore, Md.). Oct, 2012 | Pubmed ID: 22508288 Radiological Features of Familial Gorlin-Goltz Syndrome Imaging Science in Dentistry. Mar, 2012 | Pubmed ID: 22474649 Malondialdehyde Levels in Oral Sub Mucous Fibrosis: a Clinicopathological and Biochemical Study North American Journal of Medical Sciences. Mar, 2012 | Pubmed ID: 22454825 Wallenberg's Syndrome Journal of Neurosciences in Rural Practice. Jan, 2012 | Pubmed ID: 22346215 Salivary Lactate Dehydrogenase Levels in Oral Leukoplakia and Oral Squamous Cell Carcinoma: a Biochemical and Clinicopathological Study Journal of Cancer Research and Therapeutics. Jan, 2012 | Pubmed ID: 22322730 Osteoradionecrosis of the Mandible and Mastoiditis After Radiotherapy for Parotid Mucoepidermoid Carcinoma Clinical Medicine & Research. May, 2012 | Pubmed ID: 22031476 Palatal Schwannoma in an Elderly Woman Gerodontology. Jun, 2012 | Pubmed ID: 22004013 Co-occurence of Florid Cemento-osseous Dysplasia and Simple Bone Cyst: a Case Report Journal of Oral & Maxillofacial Research. 2011 | Pubmed ID: 24421997 Parry-romberg Syndrome: a Rare Case Report Journal of Oral & Maxillofacial Research. 2011 | Pubmed ID: 24421992 Contact Allergic Cheilitis Secondary to Latex Gloves: a Case Report Journal of Oral & Maxillofacial Research. 2011 | Pubmed ID: 24421987 Osteogenesis Imperfecta (Type IV) with Dental Findings in Siblings Case Reports in Dentistry. 2011 | Pubmed ID: 22567450 Massive Hemoptysis During Pregnancy The Journal of the Association of Physicians of India. Oct, 2011 | Pubmed ID: 22479749 Three-dimensional Imaging of Progressive Facial Hemiatrophy (Parry-Romberg Syndrome) with Unusual Conjunctival Findings Imaging Science in Dentistry. Dec, 2011 | Pubmed ID: 22232729 Facial Talon in Mandibular Incisor: An Unusual Occurrence Dental Research Journal. Oct, 2011 | Pubmed ID: 22135696 Nevus of Ota with Buccal Mucosal Pigmentation: a Rare Case Dental Research Journal. 2011 | Pubmed ID: 22132016 A Case of a Massive Mandibular Schwannoma Journal of Neurosciences in Rural Practice. Jan, 2011 | Pubmed ID: 21716830 Dental Patient with Acromegaly: a Case Report Journal of Oral Science. Mar, 2011 | Pubmed ID: 21467827 Common Lymphatic Endothelial and Vascular Endothelial Receptor-1 Mediates the Transmigration of Regulatory T Cells Across Human Hepatic Sinusoidal Endothelium Journal of Immunology (Baltimore, Md. : 1950). Apr, 2011 | Pubmed ID: 21368224 Stevens-Johnson Syndrome: a Case Report Journal of Oral Science. Jun, 2010 | Pubmed ID: 20587964 The Role of Chemokines in the Recruitment of Lymphocytes to the Liver Digestive Diseases (Basel, Switzerland). 2010 | Pubmed ID: 20460888 Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver Journal of Immunology (Baltimore, Md. : 1950). Mar, 2010 | Pubmed ID: 20164417 A Comparative Evaluation of Microleakage of Three Different Newer Direct Composite Resins Using a Self Etching Primer in Class V Cavities: An in Vitro Study Journal of Conservative Dentistry : JCD. Oct, 2009 | Pubmed ID: 20543926 Haematological Malignancies Presenting with Acute Liver Injury: a Single-centre Experience QJM : Monthly Journal of the Association of Physicians. Dec, 2008 | Pubmed ID: 18812406 Lymphocyte Recruitment to the Liver: Molecular Insights into the Pathogenesis of Liver Injury and Hepatitis Toxicology. Dec, 2008 | Pubmed ID: 18775762 An Evaluation of the "cut and Push" Method of Percutaneous Endoscopic Gastrostomy (PEG) Removal JPEN. Journal of Parenteral and Enteral Nutrition. Jan-Feb, 2008 | Pubmed ID: 18165451 Extra-oral Knotting of Tie-over Sutures: a Novel Technique to Bolster the Split Thickness Skin Graft for a Buccal Mucosal Defect Journal of Surgical Oncology. Oct, 2003 | Pubmed ID: 14502785 Ein dreidimensionales Sphäroidmodell zur Untersuchung der Tumor-Stroma-Wechselwirkung bei hepatozellulären Karzinomen Marco Y. W. Zaki*1,2, Shishir Shetty*2, Alex L. Wilkinson2, Daniel A. Patten2, Fiona Oakley*3, Helen Reeves*4,5 1Department of Biochemistry, Faculty of Pharmacy, Minia University, 2National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, 3Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, 4Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, 5The Liver Unit, Department of Medicine, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust JoVE 62868 Cancer Research Ein Flow-Assay zur Haftung Leukozyten-Rekrutierung Human Lebersinus Endothel unter den Bedingungen der Schubspannung Studieren Shishir Shetty1, Christopher J. Weston1, David H. Adams1, Patricia F. Lalor1 1NIHR Biomedical Research Unit, Centre for Liver Research, School of Immunity and Infection, University of Birmingham JoVE 51330 Immunology and Infection
Ein dreidimensionales Sphäroidmodell zur Untersuchung der Tumor-Stroma-Wechselwirkung bei hepatozellulären Karzinomen Marco Y. W. Zaki*1,2, Shishir Shetty*2, Alex L. Wilkinson2, Daniel A. Patten2, Fiona Oakley*3, Helen Reeves*4,5 1Department of Biochemistry, Faculty of Pharmacy, Minia University, 2National Institute for Health Research Birmingham Liver Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, 3Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, 4Newcastle University Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, 5The Liver Unit, Department of Medicine, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust JoVE 62868 Cancer Research
Ein Flow-Assay zur Haftung Leukozyten-Rekrutierung Human Lebersinus Endothel unter den Bedingungen der Schubspannung Studieren Shishir Shetty1, Christopher J. Weston1, David H. Adams1, Patricia F. Lalor1 1NIHR Biomedical Research Unit, Centre for Liver Research, School of Immunity and Infection, University of Birmingham JoVE 51330 Immunology and Infection
