Shohei Koide The Recombinant Antibody Network Biography Publications Institution JoVE Articles Shohei Koide has not added a biography. If you are Shohei Koide and would like to personalize this page please email our Author Liaison for assistance. Publications A Synthetic Antibody Fragment Targeting Nicastrin Affects Assembly and Trafficking of γ-Secretase The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25352592 Proof of Dual-topology Architecture of Fluc F- Channels with Monobody Blockers Nature Communications. 2014 | Pubmed ID: 25290819 Epigenetic Dysregulation by Nickel Through Repressive Chromatin Domain Disruption Proceedings of the National Academy of Sciences of the United States of America. Oct, 2014 | Pubmed ID: 25246589 Editorial Overview: Engineering and Design: Raising the Bar Through Innovation and Integration Current Opinion in Structural Biology. Aug, 2014 | Pubmed ID: 25175941 Visualization of Arrestin Recruitment by a G-protein-coupled Receptor Nature. Aug, 2014 | Pubmed ID: 25043026 Directed Network Wiring Identifies a Key Protein Interaction in Embryonic Stem Cell Differentiation Molecular Cell. Jun, 2014 | Pubmed ID: 24910098 Dissection of the BCR-ABL Signaling Network Using Highly Specific Monobody Inhibitors to the SHP2 SH2 Domains Proceedings of the National Academy of Sciences of the United States of America. Sep, 2013 | Pubmed ID: 23980151 Recombinant Antibodies to Histone Post-translational Modifications Nature Methods. Oct, 2013 | Pubmed ID: 23955773 Conformational States and Recognition of Amyloidogenic Peptides of Human Insulin-degrading Enzyme Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23922390 Structure of Active β-arrestin-1 Bound to a G-protein-coupled Receptor Phosphopeptide Nature. May, 2013 | Pubmed ID: 23604254 Generation of High-performance Binding Proteins for Peptide Motifs by Affinity Clamping Methods in Enzymology. 2013 | Pubmed ID: 23422435 Structures of a Na+-coupled, Substrate-bound MATE Multidrug Transporter Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23341609 Generating Conformation-specific Synthetic Antibodies to Trap Proteins in Selected Functional States Methods (San Diego, Calif.). Mar, 2013 | Pubmed ID: 23280336 CDR-H3 Diversity is Not Required for Antigen Recognition by Synthetic Antibodies Journal of Molecular Biology. Feb, 2013 | Pubmed ID: 23219464 Broad Ranges of Affinity and Specificity of Anti-histone Antibodies Revealed by a Quantitative Peptide Immunoprecipitation Assay Journal of Molecular Biology. Dec, 2012 | Pubmed ID: 23041298 T Cell Receptor-like Recognition of Tumor in Vivo by Synthetic Antibody Fragment PloS One. 2012 | Pubmed ID: 22916301 Affinity Maturation of Single-domain Antibodies by Yeast Surface Display Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22886267 Structural Insights for Engineering Binding Proteins Based on Non-antibody Scaffolds Current Opinion in Structural Biology. Aug, 2012 | Pubmed ID: 22749196 Identification of a Tetratricopeptide Repeat-like Domain in the Nicastrin Subunit of γ-secretase Using Synthetic Antibodies Proceedings of the National Academy of Sciences of the United States of America. May, 2012 | Pubmed ID: 22586122 A Delicate Interplay of Structure, Dynamics, and Thermodynamics for Function: a High Pressure NMR Study of Outer Surface Protein A Biophysical Journal. Feb, 2012 | Pubmed ID: 22385863 Target-binding Proteins Based on the 10th Human Fibronectin Type III Domain (¹⁰Fn3) Methods in Enzymology. 2012 | Pubmed ID: 22230568 Teaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 Scaffold Journal of Molecular Biology. Jan, 2012 | Pubmed ID: 22198408 Targeting the SH2-kinase Interface in Bcr-Abl Inhibits Leukemogenesis Cell. Oct, 2011 | Pubmed ID: 22000011 Mechanism of Activation Gating in the Full-length KcsA K+ Channel Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21730186 Isoform-specific Monobody Inhibitors of Small Ubiquitin-related Modifiers Engineered Using Structure-guided Library Design Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21518904 A Portable RNA Sequence Whose Recognition by a Synthetic Antibody Facilitates Structural Determination Nature Structural & Molecular Biology. Jan, 2011 | Pubmed ID: 21151117 Characterization of the Raf Kinase Inhibitory Protein (RKIP) Binding Pocket: NMR-based Screening Identifies Small-molecule Ligands PloS One. 2010 | Pubmed ID: 20463977 Molecular Mechanism of Thioflavin-T Binding to Amyloid Fibrils Biochimica Et Biophysica Acta. Jul, 2010 | Pubmed ID: 20399286 A Potent and Highly Specific FN3 Monobody Inhibitor of the Abl SH2 Domain Nature Structural & Molecular Biology. Apr, 2010 | Pubmed ID: 20357770 Rational Conversion of Affinity Reagents into Label-free Sensors for Peptide Motifs by Designed Allostery ACS Chemical Biology. Mar, 2010 | Pubmed ID: 20143785 Minimalist Design of Water-soluble Cross-beta Architecture Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133689 A Designer Ligand Specific for Kv1.3 Channels from a Scorpion Neurotoxin-based Library Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 20007782 A Peptide Tag System for Facile Purification and Single-molecule Immobilization Biochemistry. Dec, 2009 | Pubmed ID: 19928925 Binding Modes of Thioflavin-T to the Single-layer Beta-sheet of the Peptide Self-assembly Mimics Journal of Molecular Biology. Dec, 2009 | Pubmed ID: 19799914 살 균 소 전시 도서관 선택 되돌릴 수 및 사이트 Biotinylation에 의해 가속 Protein Engineering, Design & Selection : PEDS. Nov, 2009 | Pubmed ID: 19737805 Generation of New Protein Functions by Nonhomologous Combinations and Rearrangements of Domains and Modules Current Opinion in Biotechnology. Aug, 2009 | Pubmed ID: 19700302 Structural Basis for Exquisite Specificity of Affinity Clamps, Synthetic Binding Proteins Generated Through Directed Domain-interface Evolution Journal of Molecular Biology. Oct, 2009 | Pubmed ID: 19646997 Raf Kinase Inhibitory Protein Protects Cells Against Locostatin-mediated Inhibition of Migration PloS One. 2009 | Pubmed ID: 19551145 Engineering of Recombinant Crystallization Chaperones Current Opinion in Structural Biology. Aug, 2009 | Pubmed ID: 19477632 Crystal Structure of Full-length KcsA in Its Closed Conformation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19346472 The Importance of Being Tyrosine: Lessons in Molecular Recognition from Minimalist Synthetic Binding Proteins ACS Chemical Biology. May, 2009 | Pubmed ID: 19298050 Raf Kinase Inhibitory Protein Function is Regulated Via a Flexible Pocket and Novel Phosphorylation-dependent Mechanism Molecular and Cellular Biology. Mar, 2009 | Pubmed ID: 19103740 Molecular Mechanism of Thioflavin-T Binding to the Surface of Beta-rich Peptide Self-assemblies Journal of Molecular Biology. Jan, 2009 | Pubmed ID: 19038267 The Promiscuity of Beta-strand Pairing Allows for Rational Design of Beta-sheet Face Inversion Journal of the American Chemical Society. Nov, 2008 | Pubmed ID: 18842042 Aromatic Cross-strand Ladders Control the Structure and Stability of Beta-rich Peptide Self-assembly Mimics Journal of Molecular Biology. Oct, 2008 | Pubmed ID: 18762191 High-throughput Analysis of the Protein Sequence-stability Landscape Using a Quantitative Yeast Surface Two-hybrid System and Fragment Reconstitution Journal of Molecular Biology. Oct, 2008 | Pubmed ID: 18674545 Understanding Mechanisms Governing Protein-protein Interactions from Synthetic Binding Interfaces Current Opinion in Structural Biology. Aug, 2008 | Pubmed ID: 18638552 A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-protein Interfaces Journal of Molecular Biology. Aug, 2008 | Pubmed ID: 18602117 Design of Protein Function Leaps by Directed Domain Interface Evolution Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18445649 Toward Chaperone-assisted Crystallography: Protein Engineering Enhancement of Crystal Packing and X-ray Phasing Capabilities of a Camelid Single-domain Antibody (VHH) Scaffold Protein Science : a Publication of the Protein Society. Jul, 2008 | Pubmed ID: 18445622 High-resolution Structure of a Self-assembly-competent Form of a Hydrophobic Peptide Captured in a Soluble Beta-sheet Scaffold Journal of Molecular Biology. Apr, 2008 | Pubmed ID: 18367205 Synthetic Antibodies for Specific Recognition and Crystallization of Structured RNA Proceedings of the National Academy of Sciences of the United States of America. Jan, 2008 | Pubmed ID: 18162543 PH Dependence of Stability of the 10th Human Fibronectin Type III Domain: a Computational Study Biotechnology Progress. Jan-Feb, 2008 | Pubmed ID: 17935345 Beta-strand Flipping and Slipping Triggered by Turn Replacement Reveal the Opportunistic Nature of Beta-strand Pairing Journal of the American Chemical Society. Nov, 2007 | Pubmed ID: 17985889 Exploring the Capacity of Minimalist Protein Interfaces: Interface Energetics and Affinity Maturation to Picomolar KD of a Single-domain Antibody with a Flat Paratope Journal of Molecular Biology. Nov, 2007 | Pubmed ID: 17888451 Phage Display for Engineering and Analyzing Protein Interaction Interfaces Current Opinion in Structural Biology. Aug, 2007 | Pubmed ID: 17870470 High-throughput Generation of Synthetic Antibodies from Highly Functional Minimalist Phage-displayed Libraries Journal of Molecular Biology. Nov, 2007 | Pubmed ID: 17825836 High-affinity Single-domain Binding Proteins with a Binary-code Interface Proceedings of the National Academy of Sciences of the United States of America. Apr, 2007 | Pubmed ID: 17420456 Hydrophobic Surface Burial is the Major Stability Determinant of a Flat, Single-layer Beta-sheet Journal of Molecular Biology. Apr, 2007 | Pubmed ID: 17335845 Identification of Regions Within the F Domain of the Human Estrogen Receptor Alpha That Are Important for Modulating Transactivation and Protein-protein Interactions Molecular Endocrinology (Baltimore, Md.). Apr, 2007 | Pubmed ID: 17185393 Monobodies: Antibody Mimics Based on the Scaffold of the Fibronectin Type III Domain Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 17041261 Atomic Structures of Peptide Self-assembly Mimics Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17093048 Atomic-resolution Crystal Structure of Borrelia Burgdorferi Outer Surface Protein A Via Surface Engineering Protein Science : a Publication of the Protein Society. Aug, 2006 | Pubmed ID: 16823038 NMR Assignment of Rat Raf Kinase Inhibitor Protein Journal of Biomolecular NMR. 2006 | Pubmed ID: 16456706 Understanding the Human Estrogen Receptor-alpha Using Targeted Mutagenesis Molecular and Cellular Endocrinology. Feb, 2006 | Pubmed ID: 16442702 Conformation-specific Affinity Purification of Proteins Using Engineered Binding Proteins: Application to the Estrogen Receptor Protein Expression and Purification. Jun, 2006 | Pubmed ID: 16325424 High-affinity Fragment Complementation of a Fibronectin Type III Domain and Its Application to Stability Enhancement Protein Science : a Publication of the Protein Society. Nov, 2005 | Pubmed ID: 16199661 Helix, Sheet, and Polyproline II Frequencies and Strong Nearest Neighbor Effects in a Restricted Coil Library Biochemistry. Jul, 2005 | Pubmed ID: 16008354 Structure-based Design of a Second-generation Lyme Disease Vaccine Based on a C-terminal Fragment of Borrelia Burgdorferi OspA Journal of Molecular Biology. Jul, 2005 | Pubmed ID: 15935380 Substrates for Cell Adhesion Prepared Via Active Site-directed Immobilization of a Protein Domain Langmuir : the ACS Journal of Surfaces and Colloids. Feb, 2004 | Pubmed ID: 15803670 Molecular Recognition Properties of FN3 Monobodies That Bind the Src SH3 Domain Chemistry & Biology. Jun, 2004 | Pubmed ID: 15217616 Conformational Heterogeneity of an Equilibrium Folding Intermediate Quantified and Mapped by Scanning Mutagenesis Journal of Molecular Biology. May, 2004 | Pubmed ID: 15099747 Unfolding Mechanics of Multiple OspA Substructures Investigated with Single Molecule Force Spectroscopy Journal of Molecular Biology. Nov, 2003 | Pubmed ID: 14583195 Mutation of Leu-536 in Human Estrogen Receptor-alpha Alters the Coupling Between Ligand Binding, Transcription Activation, and Receptor Conformation The Journal of Biological Chemistry. Jul, 2003 | Pubmed ID: 12736255 RGDWXE 시퀀스 설계 Fibronectin 유형 III 도메인 향상 된 선호도와 특이성 인간 Alphavbeta3 Integrin에 바인딩합니다 Journal of Molecular Biology. Mar, 2003 | Pubmed ID: 12595259 Exploring the Potential of the Monobody Scaffold: Effects of Loop Elongation on the Stability of a Fibronectin Type III Domain Protein Engineering. Dec, 2002 | Pubmed ID: 12601141 Backbone Dynamics and Thermodynamics of Borrelia Outer Surface Protein A Journal of Molecular Biology. Dec, 2002 | Pubmed ID: 12470954 Calorimetric Dissection of Thermal Unfolding of OspA, a Predominantly Beta-sheet Protein Containing a Single-layer Beta-sheet Journal of Molecular Biology. Nov, 2002 | Pubmed ID: 12419262 Thermodynamic and Kinetic Exploration of the Energy Landscape of Borrelia Burgdorferi OspA by Native-state Hydrogen Exchange Journal of Molecular Biology. Oct, 2002 | Pubmed ID: 12381326 Probing Protein Conformational Changes in Living Cells by Using Designer Binding Proteins: Application to the Estrogen Receptor Proceedings of the National Academy of Sciences of the United States of America. Feb, 2002 | Pubmed ID: 11818562 파지 - 표시 합성 항체 라이브러리의 확장 성 높은 처리량 선택 Shane Miersch1,2, Zhijian Li1,2, Rachel Hanna1,2, Megan E. McLaughlin1,2, Michael Hornsby1,3, Tet Matsuguchi1,3, Marcin Paduch1,4, Annika Sääf1,4, Jim Wells1,3, Shohei Koide1,4, Anthony Kossiakoff1,4, Sachdev S. Sidhu1,2 1The Recombinant Antibody Network, 2The Banting and Best Department of Medical Research, University of Toronto, 3Antibiome Center, University of California, San Francisco at Mission Bay, 4Department of Biochemistry and Molecular Biology, The University of Chicago JoVE 51492 Immunology and Infection
파지 - 표시 합성 항체 라이브러리의 확장 성 높은 처리량 선택 Shane Miersch1,2, Zhijian Li1,2, Rachel Hanna1,2, Megan E. McLaughlin1,2, Michael Hornsby1,3, Tet Matsuguchi1,3, Marcin Paduch1,4, Annika Sääf1,4, Jim Wells1,3, Shohei Koide1,4, Anthony Kossiakoff1,4, Sachdev S. Sidhu1,2 1The Recombinant Antibody Network, 2The Banting and Best Department of Medical Research, University of Toronto, 3Antibiome Center, University of California, San Francisco at Mission Bay, 4Department of Biochemistry and Molecular Biology, The University of Chicago JoVE 51492 Immunology and Infection
