Shuxun Ren Department of Anesthesiology University of California Biography Publications Institution JoVE Articles Shuxun Ren has not added a biography. If you are Shuxun Ren and would like to personalize this page please email our Author Liaison for assistance. Publications Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure JACC. Basic to Translational Science. Apr, 2019 | Pubmed ID: 31061918 RBFox2-miR-34a-Jph2 Axis Contributes to Cardiac Decompensation During Heart Failure Proceedings of the National Academy of Sciences of the United States of America. 03, 2019 | Pubmed ID: 30867288 Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans G3 (Bethesda, Md.). 11, 2018 | Pubmed ID: 30201759 Humanin Analog Enhances the Protective Effect of Dexrazoxane Against Doxorubicin-induced Cardiotoxicity American Journal of Physiology. Heart and Circulatory Physiology. 09, 2018 | Pubmed ID: 29775411 A Personalized, Multiomics Approach Identifies Genes Involved in Cardiac Hypertrophy and Heart Failure NPJ Systems Biology and Applications. 2018 | Pubmed ID: 29507758 High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure Circulation. Oct, 2017 | Pubmed ID: 28802249 Cardiac Myocyte P38α Kinase Regulates Angiogenesis Via Myocyte-endothelial Cell Cross-talk During Stress-induced Remodeling in the Heart The Journal of Biological Chemistry. 08, 2017 | Pubmed ID: 28637870 Systems Genetics Approach Identifies Gene Pathways and Adamts2 As Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice Cell Systems. Jan, 2017 | Pubmed ID: 27866946 The Chromatin-binding Protein Smyd1 Restricts Adult Mammalian Heart Growth American Journal of Physiology. Heart and Circulatory Physiology. 11, 2016 | Pubmed ID: 27663768 The Long Noncoding RNA Chaer Defines an Epigenetic Checkpoint in Cardiac Hypertrophy Nature Medicine. 10, 2016 | Pubmed ID: 27618650 Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model PLoS Genetics. Jul, 2016 | Pubmed ID: 27385019 DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States Circulation Research. Mar, 2016 | Pubmed ID: 26838786 Titration of Mitochondrial Fusion Rescues Mff-deficient Cardiomyopathy The Journal of Cell Biology. Nov, 2015 | Pubmed ID: 26598616 Mapping Genetic Contributions to Cardiac Pathology Induced by Beta-adrenergic Stimulation in Mice Circulation. Cardiovascular Genetics. Feb, 2015 | Pubmed ID: 25480693 IRE1 Phosphatase PP2Ce Regulates Adaptive ER Stress Response in the Postpartum Mammary Gland PloS One. 2014 | Pubmed ID: 25369058 Systems Proteomics of Cardiac Chromatin Identifies Nucleolin As a Regulator of Growth and Cellular Plasticity in Cardiomyocytes American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2013 | Pubmed ID: 24077883 Endothelial Deletion of Murine Jag1 Leads to Valve Calcification and Congenital Heart Defects Associated with Alagille Syndrome Development (Cambridge, England). Dec, 2012 | Pubmed ID: 23095891 Quantitative Analysis of the Chromatin Proteome in Disease Reveals Remodeling Principles and Identifies High Mobility Group Protein B2 As a Regulator of Hypertrophic Growth Molecular & Cellular Proteomics : MCP. Jan, 2012 | Pubmed ID: 22270000 Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine Hearts Circulation Research. Dec, 2011 | Pubmed ID: 22034492 Absence of Progeria-like Disease Phenotypes in Knock-in Mice Expressing a Non-farnesylated Version of Progerin Human Molecular Genetics. Feb, 2011 | Pubmed ID: 21088111 An Accumulation of Non-farnesylated Prelamin A Causes Cardiomyopathy but Not Progeria Human Molecular Genetics. Jul, 2010 | Pubmed ID: 20421363 MAPK-activated Protein Kinase-2 in Cardiac Hypertrophy and Cyclooxygenase-2 Regulation in Heart Circulation Research. Apr, 2010 | Pubmed ID: 20339119 Post-translational Regulation of Calsarcin-1 During Pressure Overload-induced Cardiac Hypertrophy Journal of Molecular and Cellular Cardiology. Jun, 2010 | Pubmed ID: 20170660 Inducible and Cardiac Specific PTEN Inactivation Protects Ischemia/reperfusion Injury Journal of Molecular and Cellular Cardiology. Feb, 2009 | Pubmed ID: 19038262 Gi Alpha 1-mediated Cardiac Electrophysiological Remodeling and Arrhythmia in Hypertrophic Cardiomyopathy Circulation. Aug, 2007 | Pubmed ID: 17646583 A Novel Mitochondrial Matrix Serine/threonine Protein Phosphatase Regulates the Mitochondria Permeability Transition Pore and is Essential for Cellular Survival and Development Genes & Development. Apr, 2007 | Pubmed ID: 17374715 Overexpression of Bone Morphogenetic Protein 10 in Myocardium Disrupts Cardiac Postnatal Hypertrophic Growth The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16798733 P38 MAP Kinase Inhibition Enables Proliferation of Adult Mammalian Cardiomyocytes Genes & Development. May, 2005 | Pubmed ID: 15870258 Oxidant Stress from Nitric Oxide Synthase-3 Uncoupling Stimulates Cardiac Pathologic Remodeling from Chronic Pressure Load The Journal of Clinical Investigation. May, 2005 | Pubmed ID: 15841206 Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice Shuxun Ren1, Sunny Chang2, Alex Tran3, Arianna Mandelli4, Yibin Wang1, Jessica J. Wang2 1Department of Anesthesiology, University of California, 2Department of Medicine, University of California, 3Department of Microbiology, Immunology & Molecular Genetics, University of California, 4Department of Molecular, Cell, and Developmental Biology, University of California JoVE 59646 Medicine
Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice Shuxun Ren1, Sunny Chang2, Alex Tran3, Arianna Mandelli4, Yibin Wang1, Jessica J. Wang2 1Department of Anesthesiology, University of California, 2Department of Medicine, University of California, 3Department of Microbiology, Immunology & Molecular Genetics, University of California, 4Department of Molecular, Cell, and Developmental Biology, University of California JoVE 59646 Medicine
