Simon Andrews Babraham Institute Biography Publications Institution JoVE Articles Simon Andrews has not added a biography. If you are Simon Andrews and would like to personalize this page please email our Author Liaison for assistance. Publications DNA Methylation Changes During Preimplantation Development Reveal Inter-species Differences and Reprogramming Events at Imprinted Genes Clinical Epigenetics. May, 2020 | Pubmed ID: 32393379 Low Rates of Mutation in Clinical Grade Human Pluripotent Stem Cells Under Different Culture Conditions Nature Communications. Mar, 2020 | Pubmed ID: 32251294 RNA Proximity Sequencing Data and Analysis Pipeline from a Human Neuroblastoma Nuclear Transcriptome Scientific Data. 01, 2020 | Pubmed ID: 31992717 A KHDC3L Mutation Resulting in Recurrent Hydatidiform Mole Causes Genome-wide DNA Methylation Loss in Oocytes and Persistent Imprinting Defects Post-fertilisation Genome Medicine. 12, 2019 | Pubmed ID: 31847873 BNC1 Regulates Cell Heterogeneity in Human Pluripotent Stem Cell-derived Epicardium Development (Cambridge, England). Dec, 2019 | Pubmed ID: 31767620 Endogenous Retroviral Insertions Drive Non-canonical Imprinting in Extra-embryonic Tissues Genome Biology. 10, 2019 | Pubmed ID: 31665063 Ageing Affects DNA Methylation Drift and Transcriptional Cell-to-cell Variability in Mouse Muscle Stem Cells Nature Communications. 09, 2019 | Pubmed ID: 31554804 RNA Proximity Sequencing Reveals the Spatial Organization of the Transcriptome in the Nucleus Nature Biotechnology. 07, 2019 | Pubmed ID: 31267103 MicroRNA-155 is Essential for the Optimal Proliferation and Survival of Plasmablast B Cells Life Science Alliance. 06, 2019 | Pubmed ID: 31097471 Correction To: Comparison of Whole-genome Bisulfite Sequencing Library Preparation Strategies Identifies Sources of Biases Affecting DNA Methylation Data Genome Biology. 02, 2019 | Pubmed ID: 30795792 FastQ Screen: A Tool for Multi-genome Mapping and Quality Control F1000Research. 2018 | Pubmed ID: 30254741 Publisher Correction: TDP-43 Gains Function Due to Perturbed Autoregulation in a Tardbp Knock-in Mouse Model of ALS-FTD Nature Neuroscience. Aug, 2018 | Pubmed ID: 29872124 Unbiased Quantification of Immunoglobulin Diversity at the DNA Level with VDJ-seq Nature Protocols. 06, 2018 | Pubmed ID: 29725123 TDP-43 Gains Function Due to Perturbed Autoregulation in a Tardbp Knock-in Mouse Model of ALS-FTD Nature Neuroscience. 04, 2018 | Pubmed ID: 29556029 Comparison of Whole-genome Bisulfite Sequencing Library Preparation Strategies Identifies Sources of Biases Affecting DNA Methylation Data Genome Biology. 03, 2018 | Pubmed ID: 29544553 Capture Hi-C Identifies Putative Target Genes at 33 Breast Cancer Risk Loci Nature Communications. 03, 2018 | Pubmed ID: 29531215 MLL2 Conveys Transcription-independent H3K4 Trimethylation in Oocytes Nature Structural & Molecular Biology. 01, 2018 | Pubmed ID: 29323282 Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination Frontiers in Immunology. 2017 | Pubmed ID: 29204143 An EndosiRNA-Based Repression Mechanism Counteracts Transposon Activation During Global DNA Demethylation in Embryonic Stem Cells Cell Stem Cell. Nov, 2017 | Pubmed ID: 29100015 Transcription and Chromatin Determinants of De Novo DNA Methylation Timing in Oocytes Epigenetics & Chromatin. 2017 | Pubmed ID: 28507606 Dietary Restriction Protects from Age-associated DNA Methylation and Induces Epigenetic Reprogramming of Lipid Metabolism Genome Biology. 03, 2017 | Pubmed ID: 28351387 Gender Differences in Global but Not Targeted Demethylation in IPSC Reprogramming Cell Reports. 01, 2017 | Pubmed ID: 28147265 DNA Methylation and Gene Expression Changes Derived from Assisted Reproductive Technologies Can Be Decreased by Reproductive Fluids ELife. 02, 2017 | Pubmed ID: 28134613 Cluster Flow: A User-friendly Bioinformatics Workflow Tool F1000Research. 2016 | Pubmed ID: 28299179 Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells Cell Reports. 12, 2016 | Pubmed ID: 27926872 Comparative Principles of DNA Methylation Reprogramming During Human and Mouse In Vitro Primordial Germ Cell Specification Developmental Cell. 10, 2016 | Pubmed ID: 27728778 MYC Activation and BCL2L11 Silencing by a Tumour Virus Through the Large-scale Reconfiguration of Enhancer-promoter Hubs ELife. Aug, 2016 | Pubmed ID: 27490482 SNPsplit: Allele-specific Splitting of Alignments Between Genomes with Known SNP Genotypes F1000Research. 2016 | Pubmed ID: 27429743 Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination Cell Reports. 06, 2016 | Pubmed ID: 27264181 RNA-binding Proteins ZFP36L1 and ZFP36L2 Promote Cell Quiescence Science (New York, N.Y.). Apr, 2016 | Pubmed ID: 27102483 Pervasive Polymorphic Imprinted Methylation in the Human Placenta Genome Research. 06, 2016 | Pubmed ID: 26769960 Ageing is Associated with Molecular Signatures of Inflammation and Type 2 Diabetes in Rat Pancreatic Islets Diabetologia. Mar, 2016 | Pubmed ID: 26699651 Localizing the Lipid Products of PI3Kγ in Neutrophils Advances in Biological Regulation. Jan, 2016 | Pubmed ID: 26596865 HiCUP: Pipeline for Mapping and Processing Hi-C Data F1000Research. 2015 | Pubmed ID: 26835000 Erratum To: Deep Sequencing and De Novo Assembly of the Mouse Occyte Transcriptome Define the Contribution of Transcription to the DNA Methylation Landscape Genome Biology. Dec, 2015 | Pubmed ID: 26635312 Molecular Signatures of Plastic Phenotypes in Two Eusocial Insect Species with Simple Societies Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26483466 Deep Sequencing and De Novo Assembly of the Mouse Oocyte Transcriptome Define the Contribution of Transcription to the DNA Methylation Landscape Genome Biology. Sep, 2015 | Pubmed ID: 26408185 ACF Chromatin-remodeling Complex Mediates Stress-induced Depressive-like Behavior Nature Medicine. Oct, 2015 | Pubmed ID: 26390241 Polycomb Repressive Complex PRC1 Spatially Constrains the Mouse Embryonic Stem Cell Genome Nature Genetics. Oct, 2015 | Pubmed ID: 26323060 Mapping Long-range Promoter Contacts in Human Cells with High-resolution Capture Hi-C Nature Genetics. Jun, 2015 | Pubmed ID: 25938943 The Pluripotent Regulatory Circuitry Connecting Promoters to Their Long-range Interacting Elements Genome Research. Apr, 2015 | Pubmed ID: 25752748 The RNA-binding Protein HuR is Essential for the B Cell Antibody Response Nature Immunology. Apr, 2015 | Pubmed ID: 25706746 Global Reorganization of the Nuclear Landscape in Senescent Cells Cell Reports. Feb, 2015 | Pubmed ID: 25640177 Epigenetic Memory of the First Cell Fate Decision Prevents Complete ES Cell Reprogramming into Trophoblast Nature Communications. Nov, 2014 | Pubmed ID: 25423963 The MiR-155-PU.1 Axis Acts on Pax5 to Enable Efficient Terminal B Cell Differentiation The Journal of Experimental Medicine. Oct, 2014 | Pubmed ID: 25288398 Unbiased Analysis of Potential Targets of Breast Cancer Susceptibility Loci by Capture Hi-C Genome Research. Nov, 2014 | Pubmed ID: 25122612 Single-cell Genome-wide Bisulfite Sequencing for Assessing Epigenetic Heterogeneity Nature Methods. Aug, 2014 | Pubmed ID: 25042786 A Screen for Hydroxymethylcytosine and Formylcytosine Binding Proteins Suggests Functions in Transcription and Chromatin Regulation Genome Biology. 2013 | Pubmed ID: 24156278 FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency Cell Stem Cell. Jul, 2013 | Pubmed ID: 23850245 Deficiency in Spliceosome-associated Factor CTNNBL1 Does Not Affect Ongoing Cell Cycling but Delays Exit from Quiescence and Results in Embryonic Lethality in Mice Cell Cycle (Georgetown, Tex.). Mar, 2013 | Pubmed ID: 23343763 The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells Molecular Cell. Dec, 2012 | Pubmed ID: 23219530 Mutual Antagonism Between IP(3)RII and MiRNA-133a Regulates Calcium Signals and Cardiac Hypertrophy The Journal of Cell Biology. Nov, 2012 | Pubmed ID: 23166348 DNA Methylation Profiles Define Stem Cell Identity and Reveal a Tight Embryonic-extraembryonic Lineage Boundary Stem Cells (Dayton, Ohio). Dec, 2012 | Pubmed ID: 23034951 An Unbiased Assessment of the Role of Imprinted Genes in an Intergenerational Model of Developmental Programming PLoS Genetics. 2012 | Pubmed ID: 22511876 DNA Methylome Analysis Using Short Bisulfite Sequencing Data Nature Methods. Jan, 2012 | Pubmed ID: 22290186 Age-dependent Axonal Transport and Locomotor Changes and Tau Hypophosphorylation in a "P301L" Tau Knockin Mouse Neurobiology of Aging. Mar, 2012 | Pubmed ID: 21492964 High-throughput Analysis of Calcium Signalling Kinetics in Astrocytes Stimulated with Different Neurotransmitters PloS One. 2011 | Pubmed ID: 22046396 Dynamic CpG Island Methylation Landscape in Oocytes and Preimplantation Embryos Nature Genetics. Jun, 2011 | Pubmed ID: 21706000 Bismark: a Flexible Aligner and Methylation Caller for Bisulfite-Seq Applications Bioinformatics (Oxford, England). Jun, 2011 | Pubmed ID: 21493656 Dynamic Regulation of 5-hydroxymethylcytosine in Mouse ES Cells and During Differentiation Nature. May, 2011 | Pubmed ID: 21460836 Large Scale Loss of Data in Low-diversity Illumina Sequencing Libraries Can Be Recovered by Deferred Cluster Calling PloS One. Jan, 2011 | Pubmed ID: 21305042 Dynamic Stage-specific Changes in Imprinted Differentially Methylated Regions During Early Mammalian Development and Prevalence of Non-CpG Methylation in Oocytes Development (Cambridge, England). Mar, 2011 | Pubmed ID: 21247965 What is the Advantage of a Transient Precursor in Autophagosome Biogenesis? Autophagy. Jan, 2011 | Pubmed ID: 20935487 PI3K Signaling Through the Dual GTPase-activating Protein ARAP3 is Essential for Developmental Angiogenesis Science Signaling. Oct, 2010 | Pubmed ID: 20978237 Difference Tracker: ImageJ Plugins for Fully Automated Analysis of Multiple Axonal Transport Parameters Journal of Neuroscience Methods. Nov, 2010 | Pubmed ID: 20869987 Deletion of the RNA-binding Proteins ZFP36L1 and ZFP36L2 Leads to Perturbed Thymic Development and T Lymphoblastic Leukemia Nature Immunology. Aug, 2010 | Pubmed ID: 20622884 Genome-wide Erasure of DNA Methylation in Mouse Primordial Germ Cells is Affected by AID Deficiency Nature. Feb, 2010 | Pubmed ID: 20098412 Preferential Associations Between Co-regulated Genes Reveal a Transcriptional Interactome in Erythroid Cells Nature Genetics. Jan, 2010 | Pubmed ID: 20010836 Global Mapping of DNA Methylation in Mouse Promoters Reveals Epigenetic Reprogramming of Pluripotency Genes PLoS Genetics. Jun, 2008 | Pubmed ID: 18584034 P-Rex2 Regulates Purkinje Cell Dendrite Morphology and Motor Coordination Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18334636 PI3K Class IB Pathway in Neutrophils Science's STKE : Signal Transduction Knowledge Environment. Oct, 2007 | Pubmed ID: 17925574 PI3K Class IB Pathway Science's STKE : Signal Transduction Knowledge Environment. Oct, 2007 | Pubmed ID: 17925573 PI(3)Kgamma Has an Important Context-dependent Role in Neutrophil Chemokinesis Nature Cell Biology. Jan, 2007 | Pubmed ID: 17173040 ARAP3 is Essential for Formation of Lamellipodia After Growth Factor Stimulation Journal of Cell Science. Feb, 2006 | Pubmed ID: 16418224 P-Rex1 Regulates Neutrophil Function Current Biology : CB. Oct, 2005 | Pubmed ID: 16243035 Regulation of P-Rex1 by Phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma Subunits The Journal of Biological Chemistry. Feb, 2005 | Pubmed ID: 15545267 TRP Channels at a Glance Journal of Cell Science. Nov, 2004 | Pubmed ID: 15537828 P-Rex2, a New Guanine-nucleotide Exchange Factor for Rac FEBS Letters. Aug, 2004 | Pubmed ID: 15304343 The PX Domain: a New Phosphoinositide-binding Module Journal of Cell Science. Mar, 2002 | Pubmed ID: 11884510 Kwantitatieve RT-PCR met hoge doorvoer in enkele en bulk C. elegans-monsters met behulp van nanofluïdische technologie Laetitia Chauve*1, Jérémie Le Pen*2,3,5, Francesca Hodge1, Pia Todtenhaupt1, Laura Biggins1, Eric A. Miska2,3,4, Simon Andrews1, Olivia Casanueva1 1Babraham Institute, 2Gurdon Institute, University of Cambridge, 3Department of Genetics, University of Cambridge, 4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, 5Laboratory of Virology and Infectious Disease, The Rockefeller University JoVE 61132 Genetics
Kwantitatieve RT-PCR met hoge doorvoer in enkele en bulk C. elegans-monsters met behulp van nanofluïdische technologie Laetitia Chauve*1, Jérémie Le Pen*2,3,5, Francesca Hodge1, Pia Todtenhaupt1, Laura Biggins1, Eric A. Miska2,3,4, Simon Andrews1, Olivia Casanueva1 1Babraham Institute, 2Gurdon Institute, University of Cambridge, 3Department of Genetics, University of Cambridge, 4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, 5Laboratory of Virology and Infectious Disease, The Rockefeller University JoVE 61132 Genetics
