Solomon H. Snyder The Solomon H. Snyder Department of Neuroscience Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Solomon H. Snyder has not added a biography. If you are Solomon H. Snyder and would like to personalize this page please email our Author Liaison for assistance. Publications Mutant Huntingtin Disrupts the Nuclear Pore Complex Neuron. Apr, 2017 | Pubmed ID: 28384479 Opportunities for the Repurposing of PARP Inhibitors for the Therapy of Non-oncological Diseases British Journal of Pharmacology. Feb, 2017 | Pubmed ID: 28213892 Neuronal Migration is Mediated by Inositol Hexakisphosphate Kinase 1 Via α-actinin and Focal Adhesion Kinase Proceedings of the National Academy of Sciences of the United States of America. Feb, 2017 | Pubmed ID: 28154132 Complementary Roles of Gasotransmitters CO and H2S in Sleep Apnea Proceedings of the National Academy of Sciences of the United States of America. Feb, 2017 | Pubmed ID: 28115703 A Life of Neurotransmitters Annual Review of Pharmacology and Toxicology. Jan, 2017 | Pubmed ID: 27483340 H2S Production by Reactive Oxygen Species in the Carotid Body Triggers Hypertension in a Rodent Model of Sleep Apnea Science Signaling. Aug, 2016 | Pubmed ID: 27531649 Transcriptional Control of Amino Acid Homeostasis is Disrupted in Huntington's Disease Proceedings of the National Academy of Sciences of the United States of America. Aug, 2016 | Pubmed ID: 27436896 Developmental Alcohol Exposure Impairs Activity-Dependent S-Nitrosylation of NDEL1 for Neuronal Maturation Cerebral Cortex (New York, N.Y. : 1991). Jul, 2016 | Pubmed ID: 27371763 Inositol Hexakisphosphate (IP6) Generated by IP5K Mediates Cullin-COP9 Signalosome Interactions and CRL Function Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016 | Pubmed ID: 26976604 Cocaine Elicits Autophagic Cytotoxicity Via a Nitric Oxide-GAPDH Signaling Cascade Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787898 Human GAPDH Is a Target of Aspirin's Primary Metabolite Salicylic Acid and Its Derivatives PloS One. 2015 | Pubmed ID: 26606248 H2S: A Novel Gasotransmitter That Signals by Sulfhydration Trends in Biochemical Sciences. Nov, 2015 | Pubmed ID: 26439534 Inositol Hexakisphosphate Kinase-3 Regulates the Morphology and Synapse Formation of Cerebellar Purkinje Cells Via Spectrin/Adducin The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2015 | Pubmed ID: 26245967 Huntington's Disease: Neural Dysfunction Linked to Inositol Polyphosphate Multikinase Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015 | Pubmed ID: 26195796 Nitric Oxide-GAPDH Transcriptional Signaling Mediates Behavioral Actions of Cocaine CNS & Neurological Disorders Drug Targets. 2015 | Pubmed ID: 26022259 Protein Kinase G-regulated Production of H2S Governs Oxygen Sensing Science Signaling. Apr, 2015 | Pubmed ID: 25900831 Protein Sulfhydration Methods in Enzymology. 2015 | Pubmed ID: 25747476 Vernon B. Mountcastle 1918-2015 Nature Neuroscience. Mar, 2015 | Pubmed ID: 25686477 Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade Cell Reports. Feb, 2015 | Pubmed ID: 25660019 Inositol Pyrophosphates Promote Tumor Growth and Metastasis by Antagonizing Liver Kinase B1 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2015 | Pubmed ID: 25617365 Modes of Physiologic H2S Signaling in the Brain and Peripheral Tissues Antioxidants & Redox Signaling. Feb, 2015 | Pubmed ID: 24684551 Neurodegeneration in Huntington's Disease Involves Loss of Cystathionine γ-lyase Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 25486189 Melanopsin Mediates Light-dependent Relaxation in Blood Vessels Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25404319 Inositol Hexakisphosphate Kinase-1 Mediates Assembly/disassembly of the CRL4-signalosome Complex to Regulate DNA Repair and Cell Death Proceedings of the National Academy of Sciences of the United States of America. Nov, 2014 | Pubmed ID: 25349427 Serine Racemase Regulated by Binding to Stargazin and PSD-95: Potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (NMDA-AMPA) Glutamate Neurotransmission Cross-talk The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25164819 Cystathionine γ-lyase Deficiency Mediates Neurodegeneration in Huntington's Disease Nature. May, 2014 | Pubmed ID: 24670645 Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2 Molecular Cell. Apr, 2014 | Pubmed ID: 24657168 Human Genome-wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response PLoS Pathogens. Feb, 2014 | Pubmed ID: 24586175 Inherent Variations in CO-H2S-mediated Carotid Body O2 Sensing Mediate Hypertension and Pulmonary Edema Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24395806 Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy The Journal of Biological Chemistry. Feb, 2014 | Pubmed ID: 24324270 AMPA Receptor Upregulation in the Nucleus Accumbens Shell of Cocaine-sensitized Rats Depends Upon S-nitrosylation of Stargazin Neuropharmacology. Feb, 2014 | Pubmed ID: 24035918 Dexras1 Mediates Glucocorticoid-associated Adipogenesis and Diet-induced Obesity Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24297897 Inositol Polyphosphate Multikinase is a Coactivator for Serum Response Factor-dependent Induction of Immediate Early Genes Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24248338 Inositol Polyphosphate Multikinase is a Transcriptional Coactivator Required for Immediate Early Gene Induction Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013 | Pubmed ID: 24043835 Golgi Protein ACBD3 Mediates Neurotoxicity Associated with Huntington's Disease Cell Reports. Sep, 2013 | Pubmed ID: 24012756 Neuronal Nitric Oxide Synthase and NADPH Oxidase Interact to Affect Cognitive, Affective, and Social Behaviors in Mice Behavioural Brain Research. Nov, 2013 | Pubmed ID: 23948215 D-serine in Glia and Neurons Derives from 3-phosphoglycerate Dehydrogenase The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2013 | Pubmed ID: 23884950 Behavioral Effects of Cocaine Mediated by Nitric Oxide-GAPDH Transcriptional Signaling Neuron. May, 2013 | Pubmed ID: 23719162 Gene Transcription by P53 Requires Inositol Polyphosphate Multikinase As a Co-activator Cell Cycle (Georgetown, Tex.). Jun, 2013 | Pubmed ID: 23708509 Inositol Polyphosphate Multikinase is a Coactivator of P53-mediated Transcription and Cell Death Science Signaling. Apr, 2013 | Pubmed ID: 23550211 Sulfhydration Mediates Neuroprotective Actions of Parkin Nature Communications. 2013 | Pubmed ID: 23535647 Rhes Deletion is Neuroprotective in the 3-nitropropionic Acid Model of Huntington's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2013 | Pubmed ID: 23447628 Dexras1, a Small GTPase, is Required for Glutamate-NMDA Neurotoxicity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2013 | Pubmed ID: 23426685 Science Interminable: Blame Ben? Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23359704 S-nitrosylation of AMPA Receptor GluA1 Regulates Phosphorylation, Single-channel Conductance, and Endocytosis Proceedings of the National Academy of Sciences of the United States of America. Jan, 2013 | Pubmed ID: 23277581 Cyclic AMP-dependent Phosphorylation of Neuronal Nitric Oxide Synthase Mediates Penile Erection Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 23012472 Brain D-amino Acids: a Novel Class of Neuromodulators Amino Acids. Nov, 2012 | Pubmed ID: 22986446 H₂S Signalling Through Protein Sulfhydration and Beyond Nature Reviews. Molecular Cell Biology. Jul, 2012 | Pubmed ID: 22781905 Endogenous H2S is Required for Hypoxic Sensing by Carotid Body Glomus Cells American Journal of Physiology. Cell Physiology. Nov, 2012 | Pubmed ID: 22744006 Hydrogen Sulfide: a Gasotransmitter of Clinical Relevance Journal of Molecular Medicine (Berlin, Germany). Mar, 2012 | Pubmed ID: 22314625 Hydrogen Sulfide-linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions Molecular Cell. Jan, 2012 | Pubmed ID: 22244329 Hypoxic Regulation of the Cerebral Microcirculation is Mediated by a Carbon Monoxide-sensitive Hydrogen Sulfide Pathway Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22232681 AMP-activated Protein Kinase is Physiologically Regulated by Inositol Polyphosphate Multikinase Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22203993 Función De La Actividad Neuronal Y Señalización De MTOR En Adaptaciones De Morfina-inducida En Las Neuronas De Dopamina área Tegmental Ventral Neuron. Dec, 2011 | Pubmed ID: 22196333 Rhes, a Striatal-enriched Small G Protein, Mediates MTOR Signaling and L-DOPA-induced Dyskinesia Nature Neuroscience. Dec, 2011 | Pubmed ID: 22179112 Neurotrophin-mediated Degradation of Histone Methyltransferase by S-nitrosylation Cascade Regulates Neuronal Differentiation Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22123949 What Dopamine Does in the Brain Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22106252 Hydrogen Sulfide As Endothelium-derived Hyperpolarizing Factor Sulfhydrates Potassium Channels Circulation Research. Nov, 2011 | Pubmed ID: 21980127 Inositol Pyrophosphates As Mammalian Cell Signals Science Signaling. Aug, 2011 | Pubmed ID: 21878680 S-nitrosylation and S-palmitoylation Reciprocally Regulate Synaptic Targeting of PSD-95 Neuron. Jul, 2011 | Pubmed ID: 21745643 Inositol Hexakisphosphate Kinase 1 Regulates Neutrophil Function in Innate Immunity by Inhibiting Phosphatidylinositol-(3,4,5)-trisphosphate Signaling Nature Immunology. Jun, 2011 | Pubmed ID: 21685907 Nutrient Amino Acids Signal to MTOR Via Inositol Polyphosphate Multikinase Cell Cycle (Georgetown, Tex.). Jun, 2011 | Pubmed ID: 21633199 Serotonin, Cytokines, P11, and Depression Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21593414 Mind Molecules The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21543333 Glutathione is a Physiologic Reservoir of Neuronal Glutamate Biochemical and Biophysical Research Communications. Jun, 2011 | Pubmed ID: 21539809 Inositol Pyrophosphates in Cell Death and Life Cell Cycle (Georgetown, Tex.). Feb, 2011 | Pubmed ID: 21293185 Amino Acid Signaling to MTOR Mediated by Inositol Polyphosphate Multikinase Cell Metabolism. Feb, 2011 | Pubmed ID: 21284988 Casein Kinase-2 Mediates Cell Survival Through Phosphorylation and Degradation of Inositol Hexakisphosphate Kinase-2 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2011 | Pubmed ID: 21262846 Multiquinasa Inositol Polifosfato Es Un Fisiológica De La PI3-quinasa Que Activa a La Akt / PKB Proceedings of the National Academy of Sciences of the United States of America. Jan, 2011 | Pubmed ID: 21220345 Constituents of Bile, Bilirubin and TUDCA, Protect Against Oxidative Stress-induced Retinal Degeneration Journal of Neurochemistry. Jan, 2011 | Pubmed ID: 21054389 Huntington's Disease is a Disorder of the Corpus Striatum: Focus on Rhes (Ras Homologue Enriched in the Striatum) Neuropharmacology. Jun, 2011 | Pubmed ID: 21044641 Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain Cell. Dec, 2010 | Pubmed ID: 21145457 P53-mediated Apoptosis Requires Inositol Hexakisphosphate Kinase-2 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21078964 GAPDH Mediates Nitrosylation of Nuclear Proteins Nature Cell Biology. Nov, 2010 | Pubmed ID: 20972425 Protein Modifications Involved in Neurotransmitter and Gasotransmitter Signaling Trends in Neurosciences. Nov, 2010 | Pubmed ID: 20843563 H2S Mediates O2 Sensing in the Carotid Body Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20556885 Rhes, a Physiologic Regulator of Sumoylation, Enhances Cross-sumoylation Between the Basic Sumoylation Enzymes E1 and Ubc9 The Journal of Biological Chemistry. Jul, 2010 | Pubmed ID: 20424159 Aspartate Racemase, Generating Neuronal D-aspartate, Regulates Adult Neurogenesis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133766 Eliminación De Serina Racemasa Protege Contra La Excitotoxicidad E Isquemia Cerebral The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20107067 Hydrogen Sulfide As a Gasotransmitter Journal of Neurochemistry. Apr, 2010 | Pubmed ID: 20067586 Death-associated Protein Kinase-mediated Cell Death Modulated by Interaction with DANGER The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20053891 Molecules of Madness Cell. Dec, 2009 | Pubmed ID: 20064363 H2S Signals Through Protein S-sulfhydration Science Signaling. Nov, 2009 | Pubmed ID: 19903941 Cycling the Wagons for Biliverdin Reductase The Journal of Biological Chemistry. Nov, 2009 | Pubmed ID: 19897493 Neurotransmitters, Receptors, and Second Messengers Galore in 40 Years The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009 | Pubmed ID: 19828781 S-nitrosylation of Stargazin Regulates Surface Expression of AMPA-glutamate Neurotransmitter Receptors Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19805317 GOSPEL: a Neuroprotective Protein That Binds to GAPDH Upon S-nitrosylation Neuron. Jul, 2009 | Pubmed ID: 19607794 Obituary: Robert Furchgott (1916-2009) Nature. Jul, 2009 | Pubmed ID: 19571876 Rhes, a Striatal Specific Protein, Mediates Mutant-huntingtin Cytotoxicity Science (New York, N.Y.). Jun, 2009 | Pubmed ID: 19498170 Signaling by Gasotransmitters Science Signaling. Apr, 2009 | Pubmed ID: 19401594 Bilirubin and Glutathione Have Complementary Antioxidant and Cytoprotective Roles Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19286972 Glutamatergic Regulation of Serine Racemase Via Reversal of PIP2 Inhibition Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19193859 TRP_2, a Lipid/trafficking Domain That Mediates Diacylglycerol-induced Vesicle Fusion The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 19043047 H2S As a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine Gamma-lyase Science (New York, N.Y.). Oct, 2008 | Pubmed ID: 18948540 Regulation of Telomere Length by Fatty Acid Elongase 3 in Yeast. Involvement of Inositol Phosphate Metabolism and Ku70/80 Function The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18694931 S-nitrosylation/activation of COX-2 Mediates NMDA Neurotoxicity Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18650379 Palonosetron Exhibits Unique Molecular Interactions with the 5-HT3 Receptor Anesthesia and Analgesia. Aug, 2008 | Pubmed ID: 18633025 Nitric Oxide-induced Nuclear GAPDH Activates P300/CBP and Mediates Apoptosis Nature Cell Biology. Jul, 2008 | Pubmed ID: 18552833 Regulation of AMPA Receptor Localization in Lipid Rafts Molecular and Cellular Neurosciences. Jun, 2008 | Pubmed ID: 18411055 Inositol Productos Quinasa Hexakisfosfato Contienen Grupos Difosfato Y Trifosfato Chemistry & Biology. Mar, 2008 | Pubmed ID: 18355727 Neuroscience: a Complex in Psychosis Nature. Mar, 2008 | Pubmed ID: 18322519 Gene Deletion of Inositol Hexakisphosphate Kinase 1 Reveals Inositol Pyrophosphate Regulation of Insulin Secretion, Growth, and Spermiogenesis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18268345 HSP90 Regulates Cell Survival Via Inositol Hexakisphosphate Kinase-2 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2008 | Pubmed ID: 18195352 Modulation of D-serine Levels in Brains of Mice Lacking PICK1 Biological Psychiatry. May, 2008 | Pubmed ID: 18191108 Seeking God in the Brain--efforts to Localize Higher Brain Functions The New England Journal of Medicine. Jan, 2008 | Pubmed ID: 18172169 Julius Axelrod Proceedings of the American Philosophical Society. Mar, 2007 | Pubmed ID: 18175546 Opiate Receptor Revisited Anesthesiology. Oct, 2007 | Pubmed ID: 17893463 Pyrophosphorylation De Proteínas Por Pirofosfatos El Inositol Es Un Evento Postraduccional Proceedings of the National Academy of Sciences of the United States of America. Sep, 2007 | Pubmed ID: 17873058 Inositol Pyrophosphate Pyrotechnics Cell Metabolism. May, 2007 | Pubmed ID: 17488633 From the Cover: Antipsychotic Drug-induced Weight Gain Mediated by Histamine H1 Receptor-linked Activation of Hypothalamic AMP-kinase Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17360666 Neuronal Growth and Survival Mediated by EIF5A, a Polyamine-modified Translation Initiation Factor Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17360499 Ancient Origin of the New Developmental Superfamily DANGER PloS One. Feb, 2007 | Pubmed ID: 17301879 Nitric Oxide S-nitrosylates Serine Racemase, Mediating Feedback Inhibition of D-serine Formation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17293453 The Cationic Amino Acid Transporters CAT1 and CAT3 Mediate NMDA Receptor Activation-dependent Changes in Elaboration of Neuronal Processes Via the Mammalian Target of Rapamycin MTOR Pathway The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2007 | Pubmed ID: 17234578 Cell Signaling and Neuronal Death Annual Review of Pharmacology and Toxicology. 2007 | Pubmed ID: 16879082 Flexible Bilayers with Spontaneous Curvature Lead to Lamellar Gels and Spontaneous Vesicles Proceedings of the National Academy of Sciences of the United States of America. Dec, 2006 | Pubmed ID: 17132733 Action of TFII-I Outside the Nucleus As an Inhibitor of Agonist-induced Calcium Entry Science (New York, N.Y.). Oct, 2006 | Pubmed ID: 17023658 Neuroscience. Adam Finds an Exciting Mate Science (New York, N.Y.). Sep, 2006 | Pubmed ID: 16990538 DANGER, a Novel Regulatory Protein of Inositol 1,4,5-trisphosphate-receptor Activity The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 16990268 NMDA Receptor-nitric Oxide Transmission Mediates Neuronal Iron Homeostasis Via the GTPase Dexras1 Neuron. Aug, 2006 | Pubmed ID: 16908409 Las Alteraciones Conductuales En Ratones Machos Que Carecían Del Gen Para La D-aspartato Oxidasa Behavioural Brain Research. Aug, 2006 | Pubmed ID: 16725213 Discovering Light Effects on the Brain The American Journal of Psychiatry. May, 2006 | Pubmed ID: 16648313 Nitric Oxide-GAPDH-Siah: a Novel Cell Death Cascade Cellular and Molecular Neurobiology. Jul-Aug, 2006 | Pubmed ID: 16633896 Turning off Neurotransmitters Cell. Apr, 2006 | Pubmed ID: 16615882 D-aspartato Regula La Formación De Melanocortina Y Función: Alteraciones De La Conducta De D-aspartato Deficiencia De Oxidasa-ratones The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16525061 Neuroprotection by Pharmacologic Blockade of the GAPDH Death Cascade Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16505364 Mutant Huntingtin: Nuclear Translocation and Cytotoxicity Mediated by GAPDH Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16492755 Alternatively Spliced Neuronal Nitric Oxide Synthase Mediates Penile Erection Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16488973 Dopamine Receptor Excess and Mouse Madness Neuron. Feb, 2006 | Pubmed ID: 16476659 A Nitric Oxide Signaling Pathway Controls CREB-mediated Gene Expression in Neurons Molecular Cell. Jan, 2006 | Pubmed ID: 16427017 Messenger Molecules and Cell Death: Therapeutic Implications JAMA. Jan, 2006 | Pubmed ID: 16391220 Inducible Nitric Oxide Synthase Binds, S-nitrosylates, and Activates Cyclooxygenase-2 Science (New York, N.Y.). Dec, 2005 | Pubmed ID: 16373578 Genetics. Two Genes Link Two Distinct Psychoses Science (New York, N.Y.). Nov, 2005 | Pubmed ID: 16293746 Phospholipase C-gamma: Diverse Roles in Receptor-mediated Calcium Signaling Trends in Biochemical Sciences. Dec, 2005 | Pubmed ID: 16260143 Neuroscience at Johns Hopkins Neuron. Oct, 2005 | Pubmed ID: 16242401 Multiquinasa Inositol Polifosfato Es Una Nuclear PI3-quinasa Con La Actividad Reguladora De La Transcripción Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005 | Pubmed ID: 16123124 The Peripheral-type Benzodiazepine Receptor and Tumorigenicity: Isoquinoline Binding Protein (IBP) Antisense Knockdown in the C6 Glioma Cell Line Biochemistry. Jul, 2005 | Pubmed ID: 16026165 P53 Mediates Cellular Dysfunction and Behavioral Abnormalities in Huntington's Disease Neuron. Jul, 2005 | Pubmed ID: 15996546 S-nitrosylated GAPDH Initiates Apoptotic Cell Death by Nuclear Translocation Following Siah1 Binding Nature Cell Biology. Jul, 2005 | Pubmed ID: 15951807 S-nitrosylation of N-ethylmaleimide Sensitive Factor Mediates Surface Expression of AMPA Receptors Neuron. May, 2005 | Pubmed ID: 15944123 Huntingtin is Cleaved by Caspases in the Cytoplasm and Translocated to the Nucleus Via Perinuclear Sites in Huntington's Disease Patient Lymphoblasts Neurobiology of Disease. Nov, 2005 | Pubmed ID: 15890517 Phospholipase Cgamma1 Controls Surface Expression of TRPC3 Through an Intermolecular PH Domain Nature. Mar, 2005 | Pubmed ID: 15744307 Obituary: Julius Axelrod (1912-2004) Nature. Feb, 2005 | Pubmed ID: 15703735 Serine Racemase: Activation by Glutamate Neurotransmission Via Glutamate Receptor Interacting Protein and Mediation of Neuronal Migration Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15684087 Inositol 1,4,5-trisphosphate Receptor/GAPDH Complex Augments Ca2+ Release Via Locally Derived NADH Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15677321 Pirofosfatos Inositol Regulan La Muerte Celular Y La Longitud Del Telómero a Través Phosphoinositide 3-quinasa Relacionados Con Proteínas Quinasas Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15665079 Un Péptido Inhibidor Del Citocromo C / Bloques Del Receptor De Inositol 1,4,5-trifosfato De Enlace Rutas Celulares Intrínsecos Y Extrínsecos De La Muerte Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15665074 Hexakisfosfato Inositol Kinasa-2, Un Mediador Fisiológico De La Muerte Celular The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15533939 D-Serine As a Putative Glial Neurotransmitter Neuron Glia Biology. Aug, 2004 | Pubmed ID: 16543946 La Fosforilación De Proteínas Por Pirofosfatos Inositol Science (New York, N.Y.). Dec, 2004 | Pubmed ID: 15604408 Opiate Receptors and Beyond: 30 Years of Neural Signaling Research Neuropharmacology. 2004 | Pubmed ID: 15464143 Peripheral-type Benzodiazepine Receptor Density and in Vitro Tumorigenicity of Glioma Cell Lines Biochemical Pharmacology. Aug, 2004 | Pubmed ID: 15276076 Phospholipase C-gamma1 is a Guanine Nucleotide Exchange Factor for Dynamin-1 and Enhances Dynamin-1-dependent Epidermal Growth Factor Receptor Endocytosis Journal of Cell Science. Aug, 2004 | Pubmed ID: 15252117 Inositol 1,4,5-trifosfato Receptores Como Integradores De Señales Annual Review of Biochemistry. 2004 | Pubmed ID: 15189149 Hemo Oxigenasa-2 Es Activado Por Calcio-calmodulina The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15175337 Bilirubin Benefits: Cellular Protection by a Biliverdin Reductase Antioxidant Cycle Pediatrics. Jun, 2004 | Pubmed ID: 15173506 Autophagosome-like Vacuole Formation in Huntington's Disease Lymphoblasts Neuroreport. Jun, 2004 | Pubmed ID: 15167559 Media La De Monóxido De Carbono Polipéptido Intestinal Vasoactivo Asociada Adrenérgico / No Colinérgico Neurotransmisión Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14983060 RACK1 Binds to Inositol 1,4,5-trisphosphate Receptors and Mediates Ca2+ Release Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14983009 Inducida Por Agonista Entrada De Ca2 + Determinado Por El Inositol 1,4,5-trifosfato De Reconocimiento Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14983008 PIKE (phosphatidylinositol 3-kinase Enhancer)-A GTPase Stimulates Akt Activity and Mediates Cellular Invasion The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14761976 La Apoptosis Y El Calcio: Nuevos Roles Para El Citocromo C Y El Inositol 1,4,5-trifosfato Cell Cycle (Georgetown, Tex.). Mar, 2004 | Pubmed ID: 14726673 No Glial Death with NO Nature Cell Biology. Jan, 2004 | Pubmed ID: 14704677 PIKE GTPase: a Novel Mediator of Phosphoinositide Signaling Journal of Cell Science. Jan, 2004 | Pubmed ID: 14676271 El Citocromo C Se Une a Receptores De Inositol Trifosfato (1,4,5), Ampliando De Calcio Dependiente De La Apoptosis Nature Cell Biology. Dec, 2003 | Pubmed ID: 14608362 PI3 Kinase Enhancer-Homer Complex Couples MGluRI to PI3 Kinase, Preventing Neuronal Apoptosis Nature Neuroscience. Nov, 2003 | Pubmed ID: 14528310 Neurotransmisión Por Monóxido De Carbono Activado Por CK2 Fosforilación De La Hemo Oxigenasa-2 Neuron. Sep, 2003 | Pubmed ID: 14527438 Los Nuevos Moduladores Neuronales Annual Review of Neuroscience. 2003 | Pubmed ID: 14527267 Akt As a Mediator of Cell Death Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 14504398 Pirofosfatos Inositol Mediar En La Quimiotaxis De Dictyostelium Vía Homología Pleckstrin Dominio PtdIns (3,4,5) P3 Interacciones Cell. Sep, 2003 | Pubmed ID: 13678580 Schizophrenia: Neural Mechanisms for Novel Therapies Molecular Medicine (Cambridge, Mass.). Jan-Feb, 2003 | Pubmed ID: 12765334 D-serine and Serine Racemase Are Present in the Vertebrate Retina and Contribute to the Physiological Activation of NMDA Receptors Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12750462 Historical Review: Opioid Receptors Trends in Pharmacological Sciences. Apr, 2003 | Pubmed ID: 12707007 Disrupted-in-Schizophrenia-1 (DISC-1): Mutant Truncation Prevents Binding to NudE-like (NUDEL) and Inhibits Neurite Outgrowth Proceedings of the National Academy of Sciences of the United States of America. Jan, 2003 | Pubmed ID: 12506198 Nitrosopeptide Mapping: a Novel Methodology Reveals S-nitrosylation of Dexras1 on a Single Cysteine Residue Chemistry & Biology. Dec, 2002 | Pubmed ID: 12498886 Los Ritmos Circadianos. Monóxido De Carbono Y Relojes Science (New York, N.Y.). Dec, 2002 | Pubmed ID: 12493901 Biliverdin Reductase: a Major Physiologic Cytoprotectant Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12456881 Phospholipase C-gamma is Required for Agonist-induced Ca2+ Entry Cell. Nov, 2002 | Pubmed ID: 12437926 Forty Years of Neurotransmitters: a Personal Account Archives of General Psychiatry. Nov, 2002 | Pubmed ID: 12418931 Pirofosfatos Inositol Regular El Tráfico Endocítica Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12391334 Calpain-dependent Cleavage of Cain/cabin1 Activates Calcineurin to Mediate Calcium-triggered Cell Death Proceedings of the National Academy of Sciences of the United States of America. Jul, 2002 | Pubmed ID: 12114545 Schizophrenia: Diverse Approaches to a Complex Disease Science (New York, N.Y.). Apr, 2002 | Pubmed ID: 11976442 Neurobiology: Serotonin Sustains Serenity Nature. Mar, 2002 | Pubmed ID: 11919611 Akt-dependent Phosphorylation of Endothelial Nitric-oxide Synthase Mediates Penile Erection Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11904450 UDP-glucuronate Decarboxylase, a Key Enzyme in Proteoglycan Synthesis: Cloning, Characterization, and Localization The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11877387 Neuronal Nitric-oxide Synthase Localization Mediated by a Ternary Complex with Synapsin and CAPON Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11867766 Poly(ADP-ribose) Polymerase-1 Dependence of Stress-induced Transcription Factors and Associated Gene Expression in Glia Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11854472 Pirofosfatos Inositol Son Necesario Para Hyperrecombination ADN En Proteína Quinasa Mutante De Levadura C1 Biochemistry. Feb, 2002 | Pubmed ID: 11851397 Phospholipase C Gamma 1 is a Physiological Guanine Nucleotide Exchange Factor for the Nuclear GTPase PIKE Nature. Jan, 2002 | Pubmed ID: 11823862 Medición de la señalización del receptor acoplado a la proteína G mediante unión de GTP marcada con radio Chirag Vasavda*1, Nicholas W. Zaccor*1, Paul C. Scherer1, Charlotte J. Sumner1,2, Solomon H. Snyder1,3,4 1The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Neurology and neurosurgery, Johns Hopkins University School of Medicine, 3Departments of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine JoVE 55561 Biochemistry
Medición de la señalización del receptor acoplado a la proteína G mediante unión de GTP marcada con radio Chirag Vasavda*1, Nicholas W. Zaccor*1, Paul C. Scherer1, Charlotte J. Sumner1,2, Solomon H. Snyder1,3,4 1The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Neurology and neurosurgery, Johns Hopkins University School of Medicine, 3Departments of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine JoVE 55561 Biochemistry
