Stefan Frentzel Biological System Research (BSR) Philip Morris International R&D Biography Publications Institution JoVE Articles Stefan Frentzel has not added a biography. If you are Stefan Frentzel and would like to personalize this page please email our Author Liaison for assistance. Publications A Framework for in Vitro Systems Toxicology Assessment of E-liquids Toxicology Mechanisms and Methods. Apr, 2016 | Pubmed ID: 27117495 In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette Chemical Research in Toxicology. Jan, 2016 | Pubmed ID: 26651182 Aerosol from a Candidate Modified Risk Tobacco Product Has Reduced Effects on Chemotaxis and Transendothelial Migration Compared to Combustion of Conventional Cigarettes Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Dec, 2015 | Pubmed ID: 26432920 Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts Toxicological Sciences : an Official Journal of the Society of Toxicology. Sep, 2015 | Pubmed ID: 26085348 A Prototypic Modified Risk Tobacco Product Exhibits Reduced Effects on Chemotaxis and Transendothelial Migration of Monocytes Compared with a Reference Cigarette Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Jun, 2015 | Pubmed ID: 25839901 Characterization of the Vitrocell® 24/48 in Vitro Aerosol Exposure System Using Mainstream Cigarette Smoke Chemistry Central Journal. 2014 | Pubmed ID: 25411580 The Response of Human Nasal and Bronchial Organotypic Tissue Cultures to Repeated Whole Cigarette Smoke Exposure International Journal of Toxicology. Nov, 2014 | Pubmed ID: 25297719 In Vitro Systems Toxicology Approach to Investigate the Effects of Repeated Cigarette Smoke Exposure on Human Buccal and Gingival Organotypic Epithelial Tissue Cultures Toxicology Mechanisms and Methods. Oct, 2014 | Pubmed ID: 25046638 Altered Chromatin Architecture Underlies Progressive Impairment of the Heat Shock Response in Mouse Models of Huntington Disease The Journal of Clinical Investigation. Aug, 2011 | Pubmed ID: 21785217 The MTOR Kinase Inhibitor Everolimus Decreases S6 Kinase Phosphorylation but Fails to Reduce Mutant Huntingtin Levels in Brain and is Not Neuroprotective in the R6/2 Mouse Model of Huntington's Disease Molecular Neurodegeneration. 2010 | Pubmed ID: 20569486 Inhibitory Activity of Myelin-associated Glycoprotein on Sensory Neurons is Largely Independent of NgR1 and NgR2 and Resides Within Ig-Like Domains 4 and 5 PloS One. 2009 | Pubmed ID: 19367338 Ectodomain Shedding of Human Nogo-66 Receptor Homologue-1 by Zinc Metalloproteinases Biochemical and Biophysical Research Communications. Feb, 2005 | Pubmed ID: 15629437 Das Chemokin-Fractalkine Bei Patienten Mit Schweren Schädel-Hirn-Verletzungen Und Ein Mausmodell Der Geschlossenen Kopfverletzung Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Oct, 2004 | Pubmed ID: 15529011 Versican V2 and the Central Inhibitory Domain of Nogo-A Inhibit Neurite Growth Via P75NTR/NgR-independent Pathways That Converge at RhoA Molecular and Cellular Neurosciences. Oct, 2004 | Pubmed ID: 15485772 Zinc Metalloproteinase-mediated Cleavage of the Human Nogo-66 Receptor Journal of Cell Science. Sep, 2004 | Pubmed ID: 15331667 Anti-Nogo-A Antibody Infusion 24 Hours After Experimental Stroke Improved Behavioral Outcome and Corticospinal Plasticity in Normotensive and Spontaneously Hypertensive Rats Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2003 | Pubmed ID: 12571447 The Production of Macrophage Inflammatory Protein-2 Induced by Soluble Intercellular Adhesion Molecule-1 in Mouse Astrocytes is Mediated by Src Tyrosine Kinases and P42/44 Mitogen-activated Protein Kinase Journal of Neurochemistry. Mar, 2002 | Pubmed ID: 11948246 Expression of Fractalkine (CX3CL1) and Its Receptor, CX3CR1, During Acute and Chronic Inflammation in the Rodent CNS Glia. Mar, 2002 | Pubmed ID: 11870871 High Content Screening-Analyse die toxikologischen Wirkungen von gefährlichen und potenziell gefährlichen Inhaltsstoffe (HPHC) zur Bewertung Diego Marescotti1, Ignacio Gonzalez Suarez1, Stefano Acali1, Stephanie Johne1, Alexandra Laurent1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological System Research (BSR), Philip Morris International R&D Biology Folgenabschätzung Wiederholte Exposition von organotypischen 3D bronchiale und nasale Zellkulturmodelle zu Whole Zigarettenrauch Diana Kuehn1, Shoaib Majeed1, Emmanuel Guedj1, Remi Dulize1, Karine Baumer1, Anita Iskandar1, Stephanie Boue1, Florian Martin1, Radina Kostadinova1, Carole Mathis1, Nikolai V. Ivanov1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological Systems Research, Philip Morris International R&D, Philip Morris Products S.A. Bioengineering
High Content Screening-Analyse die toxikologischen Wirkungen von gefährlichen und potenziell gefährlichen Inhaltsstoffe (HPHC) zur Bewertung Diego Marescotti1, Ignacio Gonzalez Suarez1, Stefano Acali1, Stephanie Johne1, Alexandra Laurent1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological System Research (BSR), Philip Morris International R&D Biology
Folgenabschätzung Wiederholte Exposition von organotypischen 3D bronchiale und nasale Zellkulturmodelle zu Whole Zigarettenrauch Diana Kuehn1, Shoaib Majeed1, Emmanuel Guedj1, Remi Dulize1, Karine Baumer1, Anita Iskandar1, Stephanie Boue1, Florian Martin1, Radina Kostadinova1, Carole Mathis1, Nikolai V. Ivanov1, Stefan Frentzel1, Julia Hoeng1, Manuel C. Peitsch1 1Biological Systems Research, Philip Morris International R&D, Philip Morris Products S.A. Bioengineering