Articles by Stephan Mathias Jakob in JoVE
Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements Siamak Djafarzadeh1, Stephan Mathias Jakob1 1Department of Intensive Care Medicine, Inselspital, Bern University Hospital Here, a quadriceps muscle specimen is taken from an anaesthetized pig and mitochondria are isolated by differential centrifugation. Then, the respiratory rates of mitochondrial respiratory chain complexes I, II and IV are determined using high-resolution respirometry.
Other articles by Stephan Mathias Jakob on PubMed
Increasing Mean Arterial Blood Pressure in Sepsis: Effects on Fluid Balance, Vasopressor Load and Renal Function Critical Care (London, England). 2013 | Pubmed ID: 23363690 The objective of this study was to evaluate the effects of two different mean arterial blood pressure (MAP) targets on needs for resuscitation, organ dysfunction, mitochondrial respiration and inflammatory response in a long-term model of fecal peritonitis.