Stephan E. Lehnart Heart Research Center Goettingen Biography Publications Institution JoVE Articles Stephan E. Lehnart has not added a biography. If you are Stephan E. Lehnart and would like to personalize this page please email our Author Liaison for assistance. Publications Toward Panoramic in Situ Mapping of Action Potential Propagation in Transgenic Hearts to Investigate Initiation and Therapeutic Control of Arrhythmias Frontiers in Physiology. 2014 | Pubmed ID: 25249982 Transgenic Mice for Real-time Visualization of CGMP in Intact Adult Cardiomyocytes Circulation Research. Apr, 2014 | Pubmed ID: 24599804 Tuning the Electrical Properties of the Heart by Differential Trafficking of KATP Ion Channel Complexes Journal of Cell Science. May, 2014 | Pubmed ID: 24569881 Imaging T-tubules: Dynamic Membrane Structures for Deep Functions Cardiovascular Research. May, 2013 | Pubmed ID: 23504549 Superresolution Microscopy in Heart - Cardiac Nanoscopy Journal of Molecular and Cellular Cardiology. May, 2013 | Pubmed ID: 23219451 Understanding the Physiology of Heart Failure Through Cellular and in Vivo Models-towards Targeting of Complex Mechanisms Experimental Physiology. Mar, 2013 | Pubmed ID: 23064508 Stimulated Emission Depletion Live-cell Super-resolution Imaging Shows Proliferative Remodeling of T-tubule Membrane Structures After Myocardial Infarction Circulation Research. Aug, 2012 | Pubmed ID: 22723297 Ablation of Junctin or Triadin is Associated with Increased Cardiac Injury Following Ischaemia/reperfusion Cardiovascular Research. May, 2012 | Pubmed ID: 22411973 Rationale, Objectives, and Design of the EUTrigTreat Clinical Study: a Prospective Observational Study for Arrhythmia Risk Stratification and Assessment of Interrelationships Among Repolarization Markers and Genotype Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. Mar, 2012 | Pubmed ID: 22117037 SAP97 and Dystrophin Macromolecular Complexes Determine Two Pools of Cardiac Sodium Channels Nav1.5 in Cardiomyocytes Circulation Research. Feb, 2011 | Pubmed ID: 21164104 Phosphorylation of the Ryanodine Receptor Mediates the Cardiac Fight or Flight Response in Mice The Journal of Clinical Investigation. Dec, 2010 | Pubmed ID: 21099118 Differential Cardiac Remodeling in Preload Versus Afterload Circulation. Sep, 2010 | Pubmed ID: 20733099 An Antidote for Calcium Leak: Targeting Molecular Arrhythmia Mechanisms Journal of Molecular and Cellular Cardiology. Feb, 2010 | Pubmed ID: 19931542 K201 Improves Aspects of the Contractile Performance of Human Failing Myocardium Via Reduction in Ca2+ Leak from the Sarcoplasmic Reticulum Basic Research in Cardiology. Mar, 2010 | Pubmed ID: 19718543 Abnormalities of Calcium Metabolism and Myocardial Contractility Depression in the Failing Heart Heart Failure Reviews. Dec, 2009 | Pubmed ID: 19434491 Inhibition of Extracellular Signal-regulated Kinase Signaling to Prevent Cardiomyopathy Caused by Mutation in the Gene Encoding A-type Lamins Human Molecular Genetics. Jan, 2009 | Pubmed ID: 18927124 Arrhythmogenic Right Ventricular Cardiomyopathy in Boxer Dogs is Associated with Calstabin2 Deficiency Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology. Jun, 2008 | Pubmed ID: 18515204 Leaky Ca2+ Release Channel/ryanodine Receptor 2 Causes Seizures and Sudden Cardiac Death in Mice The Journal of Clinical Investigation. Jun, 2008 | Pubmed ID: 18483626 Remodeling of Ryanodine Receptor Complex Causes "leaky" Channels: a Molecular Mechanism for Decreased Exercise Capacity Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18268335 Ereditato Aritmie: Un National Heart, Lung E Blood Institute E Ufficio Delle Malattie Rare Workshop Consensus Report Circa La Diagnosi, Fenotipi, Meccanismi Molecolari E Approcci Terapeutici Per Cardiomiopatie Primarie Delle Mutazioni Del Gene Che Interessa La Funzione Dei Canali Ionici Circulation. Nov, 2007 | Pubmed ID: 17998470 Modulation of the Ryanodine Receptor and Intracellular Calcium Annual Review of Biochemistry. 2007 | Pubmed ID: 17506640 Novel Targets for Treating Heart and Muscle Disease: Stabilizing Ryanodine Receptors and Preventing Intracellular Calcium Leak Current Opinion in Pharmacology. Apr, 2007 | Pubmed ID: 17306622 Phosphodiesterase 4D and Heart Failure: a Cautionary Tale Expert Opinion on Therapeutic Targets. Oct, 2006 | Pubmed ID: 16981825 Stabilizzazione Del Recettore Rianodinico Cardiaco Previene Aritmie E Perdita Di Calcio Intracellulare Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16672364 La Rianodinico Recettore Calcio Rilascio Canale PKA Fosforilazione: Un Mediatore Critico Di Progressione Della Insufficienza Cardiaca Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16407108 Deficit Di Fosfodiesterasi 4 D Del Complesso Del Recettore Rianodinico Promuove Insufficienza Cardiaca E Aritmie Cell. Oct, 2005 | Pubmed ID: 16213210 Rianodinico Recettore-mirata Terapia Antiaritmici Annals of the New York Academy of Sciences. Jun, 2005 | Pubmed ID: 16093511 Interazioni Tra Domini Di Recettore Rianodinico Difettosi Possono Contribuire Alla Perdita Di Ca2 + Intracellulare: Un Romanzo Obiettivo Terapeutico Nello Scompenso Cardiaco Circulation. Jun, 2005 | Pubmed ID: 15983258 Migliorare Calstabin Legame Con I Recettori Rianodinico Migliora La Funzione Del Muscolo Cardiaco E Scheletrico in Insufficienza Cardiaca Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 15972811 Regolamento Di Recettore Rianodinico Cardiaco Difettoso Durante Fibrillazione Atriale Circulation. Apr, 2005 | Pubmed ID: 15851612 Malattia Di Rilascio E Cardiaco Di Calcio Intracellulare Annual Review of Physiology. 2005 | Pubmed ID: 15709953 Deficit Di Calstabin, Rianodinico Recettori E Morte Cardiaca Improvvisa Biochemical and Biophysical Research Communications. Oct, 2004 | Pubmed ID: 15336974 Funzione Del Recettore Rianodinico Cardiaco E Regolamento Nella Malattia Di Cuore Annals of the New York Academy of Sciences. May, 2004 | Pubmed ID: 15201156 Morte Improvvisa Nel Familiare Tachicardia Ventricolare Polimorfica, Associato a Perdita Di (recettore Rianodinico) Canale Di Rilascio Del Calcio Circulation. Jun, 2004 | Pubmed ID: 15197150 Protezione Da Aritmia Cardiaca Attraverso Calstabin2 Di Proteina Stabilizzante Del Recettore Rianodinico Science (New York, N.Y.). Apr, 2004 | Pubmed ID: 15073377 Ca2 + Fosforilazione Di Calmodulin-dependent Protein Kinase II Regola Il Recettore Rianodinico Cardiaco Circulation Research. Apr, 2004 | Pubmed ID: 15016728 Immunophilins and Coupled Gating of Ryanodine Receptors Current Topics in Medicinal Chemistry. 2003 | Pubmed ID: 12871170 Deficit Di FKBP12.6 E Calcio Difettoso Rilascio Funzione Di Canale (recettore Rianodinico) Legate Alla Morte Cardiaca Improvvisa Indotta Da Esercizio Cell. Jun, 2003 | Pubmed ID: 12837242 PKA Phosphorylation Activates the Calcium Release Channel (ryanodine Receptor) in Skeletal Muscle: Defective Regulation in Heart Failure The Journal of Cell Biology. Mar, 2003 | Pubmed ID: 12629052 Coronary Perfusion Cocktails for in Vivo Gene Transfer Methods in Molecular Biology (Clifton, N.J.). 2003 | Pubmed ID: 12597011 Beta-blocco Intracellulare: Sovraespressione Di Galpha(i2) Deprime La Risposta Beta-adrenergici Nel Miocardio Intatto Cardiovascular Research. Aug, 2002 | Pubmed ID: 12123769 Potentiation of Beta-adrenergic Inotropic Response by Pyruvate in Failing Human Myocardium Cardiovascular Research. Jan, 2002 | Pubmed ID: 11744019 Analisi della membrana tubolare reti in Cardiac miociti da atri e ventricoli Eva Wagner*1,2,3, Sören Brandenburg*1,2, Tobias Kohl1,2, Stephan E. Lehnart1,2,3,4 1Heart Research Center Goettingen, 2Clinic of Cardiology & Pulmonology, University Medical Center Goettingen, 3German Center for Cardiovascular Research (DZHK) partner site Goettingen, 4BioMET, Center for Biomedical Engineering & Technology, University of Maryland School of Medicine JoVE 51823 Bioengineering
Analisi della membrana tubolare reti in Cardiac miociti da atri e ventricoli Eva Wagner*1,2,3, Sören Brandenburg*1,2, Tobias Kohl1,2, Stephan E. Lehnart1,2,3,4 1Heart Research Center Goettingen, 2Clinic of Cardiology & Pulmonology, University Medical Center Goettingen, 3German Center for Cardiovascular Research (DZHK) partner site Goettingen, 4BioMET, Center for Biomedical Engineering & Technology, University of Maryland School of Medicine JoVE 51823 Bioengineering
