Stephen J. Nicholls Monash Cardiovascular Research Centre Biography Publications Institution JoVE Articles Stephen J. Nicholls has not added a biography. If you are Stephen J. Nicholls and would like to personalize this page please email our Author Liaison for assistance. Publications Atrial Fibrillation Incidence, Prevalence, Predictors and Adverse Outcomes in Acute Coronary Syndromes: a Pooled Analysis of Data from 8 Million Patients Journal of Cardiovascular Electrophysiology. Jan, 2022 | Pubmed ID: 34981859 Multimodality Intravascular Imaging of High-Risk Coronary Plaque JACC. Cardiovascular Imaging. Jan, 2022 | Pubmed ID: 34023267 Shining Light on the Impact of Air Pollution JACC. Cardiovascular Imaging. Dec, 2021 | Pubmed ID: 34922876 The Impact of Hypo-attenuated Leaflet Thickening on Haemodynamic Valve Deterioration Following Transcatheter Aortic Valve Replacement Journal of Cardiovascular Computed Tomography. Nov, 2021 | Pubmed ID: 34852974 Erratum to "C-Reactive Protein Levels and Plaque Regression with Evolocumab: Insights From GLAGOV" [American Journal of Preventive Cardiology 3C (2020) 100091] American Journal of Preventive Cardiology. Jun, 2021 | Pubmed ID: 34374706 The Riskier Lipid: What Is on the HORIZON for Lipoprotein (a) and Should There Be Lp(a) Screening for All? Current Cardiology Reports. 07, 2021 | Pubmed ID: 34196823 Pericoronary Adipose Tissue Attenuation Is Associated with High-Risk Plaque and Subsequent Acute Coronary Syndrome in Patients with Stable Coronary Artery Disease Cells. 05, 2021 | Pubmed ID: 34068518 The Emerging Role of CT-Based Imaging in Adipose Tissue and Coronary Inflammation Cells. 05, 2021 | Pubmed ID: 34068406 Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk: A Secondary Analysis of the STRENGTH Trial JAMA Cardiology. May, 2021 | Pubmed ID: 33993205 Circadian Disruption by Short Light Exposure and a High Energy Diet Impairs Glucose Tolerance and Increases Cardiac Fibrosis in Psammomys Obesus Scientific Reports. 05, 2021 | Pubmed ID: 33958671 Cardiac Computed Tomography Radiomics for the Non-Invasive Assessment of Coronary Inflammation Cells. 04, 2021 | Pubmed ID: 33921502 Effect of Apabetalone on Cardiovascular Events in Diabetes, CKD, and Recent Acute Coronary Syndrome: Results from the BETonMACE Randomized Controlled Trial Clinical Journal of the American Society of Nephrology : CJASN. 05, 2021 | Pubmed ID: 33906908 Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk-Reply JAMA. 04, 2021 | Pubmed ID: 33821901 Omega-3 Fatty Acids Ameliorate Vascular Inflammation: A Rationale for Their Atheroprotective Effects Atherosclerosis. 05, 2021 | Pubmed ID: 33812168 Assessing the Impact of PCSK9 Inhibition on Coronary Plaque Phenotype with Optical Coherence Tomography: Rationale and Design of the Randomized, Placebo-controlled HUYGENS Study Cardiovascular Diagnosis and Therapy. Feb, 2021 | Pubmed ID: 33708484 Clinical Predictors and Sequelae of Computed Tomography Defined Leaflet Thrombosis Following Transcatheter Aortic Valve Replacement at Medium-term Follow-up Heart and Vessels. Sep, 2021 | Pubmed ID: 33660057 Elevated HDL-bound MiR-181c-5p Level is Associated with Diabetic Vascular Complications in Australian Aboriginal People Diabetologia. 06, 2021 | Pubmed ID: 33651121 Long-term Outcomes Following Endovascular and Surgical Revascularization for Peripheral Artery Disease: a Propensity Score-matched Analysis European Heart Journal. 12, 2021 | Pubmed ID: 33624819 Combination of Bempedoic Acid, Ezetimibe, and Atorvastatin in Patients with Hypercholesterolemia: A Randomized Clinical Trial Atherosclerosis. 03, 2021 | Pubmed ID: 33514449 Rationale and Design of the CLEAR-outcomes Trial: Evaluating the Effect of Bempedoic Acid on Cardiovascular Events in Patients with Statin Intolerance American Heart Journal. 05, 2021 | Pubmed ID: 33470195 Can CMR Elucidate the Cardiovascular Benefit of SGLT2 Inhibitors? JACC. Cardiovascular Imaging. 06, 2021 | Pubmed ID: 33454271 Apabetalone and Hospitalization for Heart Failure in Patients Following an Acute Coronary Syndrome: a Prespecified Analysis of the BETonMACE Study Cardiovascular Diabetology. 01, 2021 | Pubmed ID: 33413345 Effect of Empagliflozin on Exercise Ability and Symptoms in Heart Failure Patients with Reduced and Preserved Ejection Fraction, with and Without Type 2 Diabetes European Heart Journal. 02, 2021 | Pubmed ID: 33351892 Feasibility and Validity of Computed Tomography-Derived Fractional Flow Reserve in Patients With Severe Aortic Stenosis: The CAST-FFR Study Circulation. Cardiovascular Interventions. 01, 2021 | Pubmed ID: 33322917 Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis The New England Journal of Medicine. 01, 2021 | Pubmed ID: 33200890 A Systematic Review and Meta-analysis of Gender Differences in Long-term Mortality and Cardiovascular Events in Peripheral Artery Disease Journal of Vascular Surgery. 04, 2021 | Pubmed ID: 33161072 Pericoronary Adipose Tissue Computed Tomography Attenuation Distinguishes Different Stages of Coronary Artery Disease: a Cross-sectional Study European Heart Journal. Cardiovascular Imaging. 02, 2021 | Pubmed ID: 33106867 Cardiovascular Bioimaging of Nitric Oxide: Achievements, Challenges, and the Future Medicinal Research Reviews. 01, 2021 | Pubmed ID: 33075148 Rationale and Design of ApoA-I Event Reducing in Ischemic Syndromes II (AEGIS-II): A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects After Acute Myocardial Infarction American Heart Journal. 01, 2021 | Pubmed ID: 33065120 Women With Spontaneous Coronary Artery Dissection Are at Increased Risk of Iatrogenic Coronary Artery Dissection Heart, Lung & Circulation. Jan, 2021 | Pubmed ID: 32952036 Previous Pre-Eclampsia, Gestational Diabetes and Hypertension Place Women at High Cardiovascular Risk: But Do We Ask? Heart, Lung & Circulation. Jan, 2021 | Pubmed ID: 32843295 Gender Differences in Healthy Lifestyle Adherence Following Percutaneous Coronary Intervention for Coronary Artery Disease Heart, Lung & Circulation. Jan, 2021 | Pubmed ID: 32843294 Progression of Coronary Atherosclerosis in Patients Without Standard Modifiable Risk Factors American Journal of Preventive Cardiology. Dec, 2020 | Pubmed ID: 34327476 Tackling Cardiometabolic Risk in the Asia Pacific Region American Journal of Preventive Cardiology. Dec, 2020 | Pubmed ID: 34327472 C-reactive Protein Levels and Plaque Regression with Evolocumab: Insights from GLAGOV American Journal of Preventive Cardiology. Sep, 2020 | Pubmed ID: 34327467 The Role of Intracoronary Imaging in Translational Research Cardiovascular Diagnosis and Therapy. Oct, 2020 | Pubmed ID: 33224769 Effect of High-Dose Omega-3 Fatty Acids Vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk: The STRENGTH Randomized Clinical Trial JAMA. 12, 2020 | Pubmed ID: 33190147 Inflammation in Coronary Atherosclerosis and Its Therapeutic Implications Cardiovascular Drugs and Therapy. Nov, 2020 | Pubmed ID: 33170943 The Fish-oil Paradox Current Opinion in Lipidology. 12, 2020 | Pubmed ID: 33027227 Non-hyperaemic Pressure Ratios to Guide Percutaneous Coronary Intervention Open Heart. 10, 2020 | Pubmed ID: 33004619 Myocardial Infarction Associates With a Distinct Pericoronary Adipose Tissue Radiomic Phenotype: A Prospective Case-Control Study JACC. Cardiovascular Imaging. 11, 2020 | Pubmed ID: 32861654 Lack of Strategic Funding and Long-Term Job Security Threaten to Have Profound Effects on Cardiovascular Researcher Retention in Australia Heart, Lung & Circulation. Nov, 2020 | Pubmed ID: 32839116 Cardiovascular Disease and COVID-19: Australian and New Zealand Consensus Statement The Medical Journal of Australia. 08, 2020 | Pubmed ID: 32734645 Statin Intolerance: an Updated, Narrative Review Mainly Focusing on Muscle Adverse Effects Expert Opinion on Drug Metabolism & Toxicology. Sep, 2020 | Pubmed ID: 32729743 Ultrathin Monolithic 3D Printed Optical Coherence Tomography Endoscopy for Preclinical and Clinical Use Light, Science & Applications. 2020 | Pubmed ID: 32704357 Statins for Primary Prevention in the Elderly: The Importance of Rigorous Evidence JAMA. 07, 2020 | Pubmed ID: 32633787 Fractional Flow Reserve Following Percutaneous Coronary Intervention Journal of Interventional Cardiology. 2020 | Pubmed ID: 32565755 Mental Health and Psychosocial Challenges in the COVID-19 Pandemic: Food for Thought for Cardiovascular Health Care Professionals Heart, Lung & Circulation. Jul, 2020 | Pubmed ID: 32561126 Familial Hypercholesterolemia in a Healthy Elderly Population Circulation. Genomic and Precision Medicine. 08, 2020 | Pubmed ID: 32522009 Optimising Secondary Prevention and Cardiac Rehabilitation for Atherosclerotic Cardiovascular Disease During the COVID-19 Pandemic: A Position Statement From the Cardiac Society of Australia and New Zealand (CSANZ) Heart, Lung & Circulation. Jul, 2020 | Pubmed ID: 32473781 Exploring the Relationship Between Biomechanical Stresses and Coronary Atherosclerosis Atherosclerosis. 06, 2020 | Pubmed ID: 32438198 Angiographic Functional Scoring of Coronary Artery Disease Predicts Mortality in Patients With Severe Aortic Stenosis Undergoing TAVR Cardiovascular Revascularization Medicine : Including Molecular Interventions. 11, 2020 | Pubmed ID: 32359889 Progression of Ultrasound Plaque Attenuation and Low Echogenicity Associates with Major Adverse Cardiovascular Events European Heart Journal. 08, 2020 | Pubmed ID: 32243512 Effect of Apabetalone Added to Standard Therapy on Major Adverse Cardiovascular Events in Patients With Recent Acute Coronary Syndrome and Type 2 Diabetes: A Randomized Clinical Trial JAMA. 04, 2020 | Pubmed ID: 32219359 2-Year Outcomes After Stenting of Lipid-Rich and Nonrich Coronary Plaques Journal of the American College of Cardiology. 03, 2020 | Pubmed ID: 32216905 The Mystery of Evacetrapib - Why Are CETP Inhibitors Failing? Expert Review of Cardiovascular Therapy. 03, 2020 | Pubmed ID: 32200670 Translating Evidence from Clinical Trials of Omega-3 Fatty Acids to Clinical Practice Future Cardiology. 07, 2020 | Pubmed ID: 32180456 Effect of CETP Inhibition with Evacetrapib in Patients with Diabetes Mellitus Enrolled in the ACCELERATE Trial BMJ Open Diabetes Research & Care. 03, 2020 | Pubmed ID: 32179516 Dalcetrapib Reduces Risk of New-Onset Diabetes in Patients With Coronary Heart Disease Diabetes Care. 05, 2020 | Pubmed ID: 32144166 Low-density Lipoproteins Cause Atherosclerotic Cardiovascular Disease: Pathophysiological, Genetic, and Therapeutic Insights: a Consensus Statement from the European Atherosclerosis Society Consensus Panel European Heart Journal. 06, 2020 | Pubmed ID: 32052833 Impact of Side-Branch Predilation on Angiographic Outcomes in Non-Left Main Coronary Bifurcation Lesions The Journal of Invasive Cardiology. Feb, 2020 | Pubmed ID: 31958071 Association of High-density Lipoprotein Particle Concentration with Cardiovascular Risk Following Acute Coronary Syndrome: A Case-cohort Analysis of the Dal-Outcomes Trial American Heart Journal. 03, 2020 | Pubmed ID: 31927126 Genome-Wide Polygenic Score and Cardiovascular Outcomes With Evacetrapib in Patients With High-Risk Vascular Disease: A Nested Case-Control Study Circulation. Genomic and Precision Medicine. 02, 2020 | Pubmed ID: 31898914 Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action JAMA Cardiology. Jan, 2020 | Pubmed ID: 31895433 Impact of Baseline Glycemic Control on Residual Cardiovascular Risk in Patients With Diabetes Mellitus and High-Risk Vascular Disease Treated With Statin Therapy Journal of the American Heart Association. 01, 2020 | Pubmed ID: 31852422 Using Genetics to Guide Treatment and Drug Development in Cardiovascular Medicine: Time to Reveal the Proof in the Pudding Cardiovascular Research. 02, 2020 | Pubmed ID: 31845983 Cholesterol Crystal-induced Coronary Inflammation: Insights from Optical Coherence Tomography and Pericoronary Adipose Tissue Computed Tomography Attenuation Journal of Cardiovascular Computed Tomography. May - Jun, 2020 | Pubmed ID: 31810855 Remnant Cholesterol, Coronary Atheroma Progression and Clinical Events in Statin-treated Patients with Coronary Artery Disease European Journal of Preventive Cardiology. 07, 2020 | Pubmed ID: 31744333 Quantitative and Qualitative Coronary Plaque Assessment Using Computed Tomography Coronary Angiography: A Comparison With Intravascular Ultrasound Heart, Lung & Circulation. Jun, 2020 | Pubmed ID: 31564511 High-Dose Omega-3 Fatty Acids in Cardiovascular Prevention: Finally Living Up to Their Potential? American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions. Feb, 2020 | Pubmed ID: 31485851 Exposure and Response Analysis of Aleglitazar on Cardiovascular Risk Markers and Safety Outcomes: An Analysis of the AleCardio Trial Diabetes, Obesity & Metabolism. 01, 2020 | Pubmed ID: 31468659 Awareness of Familial Hypercholesterolemia Among Healthcare Providers Involved in the Management of Acute Coronary Syndrome in Victoria, Australia CJC Open. Jul, 2019 | Pubmed ID: 32159103 High-Energy Diet and Shorter Light Exposure Drives Markers of Adipocyte Dysfunction in Visceral and Subcutaneous Adipose Depots of International Journal of Molecular Sciences. Dec, 2019 | Pubmed ID: 31847097 Plasma Aldosterone Levels Are Not Associated With Cardiovascular Events Among Patients With High-Risk Vascular Disease: Insights From the ACCELERATE Trial Journal of the American Heart Association. 12, 2019 | Pubmed ID: 31752637 Plaque Calcification: Do Lipoproteins Have a Role? Arteriosclerosis, Thrombosis, and Vascular Biology. 10, 2019 | Pubmed ID: 31462089 Pharmacological Lipid-modification Therapies for Prevention of Ischaemic Heart Disease: Current and Future Options Lancet (London, England). Aug, 2019 | Pubmed ID: 31448741 Aortic Distensibility is Associated with Both Resting and Hyperemic Coronary Blood Flow American Journal of Physiology. Heart and Circulatory Physiology. 10, 2019 | Pubmed ID: 31441693 Current State-of-play in Spontaneous Coronary Artery Dissection Cardiovascular Diagnosis and Therapy. Jun, 2019 | Pubmed ID: 31275818 The Keeping on Track Study: Exploring the Activity Levels and Utilization of Healthcare Services of Acute Coronary Syndrome (ACS) Patients in the First 30-Days After Discharge from Hospital Medical Sciences (Basel, Switzerland). Apr, 2019 | Pubmed ID: 31010168 Visit-to-Visit Blood Pressure Variability, Coronary Atheroma Progression, and Clinical Outcomes JAMA Cardiology. 05, 2019 | Pubmed ID: 30969323 Ticagrelor Versus Clopidogrel in Patients With STEMI Treated With Fibrinolysis: TREAT Trial Journal of the American College of Cardiology. 06, 2019 | Pubmed ID: 30898608 Serial Coronary Plaque Assessment Using Computed Tomography Coronary Angiography Circulation. Cardiovascular Imaging. 03, 2019 | Pubmed ID: 30879331 Remnant Cholesterol and Coronary Atherosclerotic Plaque Burden Assessed by Computed Tomography Coronary Angiography Atherosclerosis. 05, 2019 | Pubmed ID: 30870704 Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease JAMA. 01, 2019 | Pubmed ID: 30694319 Rivaroxaban With or Without Aspirin for the Secondary Prevention of Cardiovascular Disease: Clinical Implications of the COMPASS Trial American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions. Aug, 2019 | Pubmed ID: 30680652 Do Cholesteryl Ester Transfer Protein Inhibitors Have a Role in the Treatment of Cardiovascular Disease? American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions. Jun, 2019 | Pubmed ID: 30610681 טומוגרפיה קוהרנטית אופטית מבוסס ביומכנית נוזל מבנה ניתוח של טרשת עורקים כלילית התקדמות Harry J. Carpenter1, Mergen H. Ghayesh1, Anthony C. Zander1, Juanita L. Ottaway2, Giuseppe Di Giovanni3, Stephen J. Nicholls4, Peter J. Psaltis3,5,6 1School of Mechanical Engineering, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Vascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), 4Monash Cardiovascular Research Centre, 5Adelaide Medical School, University of Adelaide, 6Department of Cardiology, Central Adelaide Local Health Network JoVE 62933 Bioengineering
טומוגרפיה קוהרנטית אופטית מבוסס ביומכנית נוזל מבנה ניתוח של טרשת עורקים כלילית התקדמות Harry J. Carpenter1, Mergen H. Ghayesh1, Anthony C. Zander1, Juanita L. Ottaway2, Giuseppe Di Giovanni3, Stephen J. Nicholls4, Peter J. Psaltis3,5,6 1School of Mechanical Engineering, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Vascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), 4Monash Cardiovascular Research Centre, 5Adelaide Medical School, University of Adelaide, 6Department of Cardiology, Central Adelaide Local Health Network JoVE 62933 Bioengineering