Stephen M. Sykes
Daniela Di Marcantonio is a Postdoctoral Fellow in Dr. Sykes Lab at the Research Institute of Fox Chase Cancer Center, Philadelphia, US. She received her Bachelor's degree in Biotechnology from the University of Teramo, Italy in 2007 and completed her Master's degree in Biotechnology and Regenerative Medicine from University of Parma, Italy in 2010. There, she joined Dr. Vitale’s lab to study physiological signaling involved in normal muscle stem cell activation and differentiation and received her PhD in Physiopathology in 2015.
In 2015 she moved to Philadelphia to join Dr Sykes’ Lab as a Postdoctoral Fellow. Her work has revealed how protein kinase C epsilon is a positive regulator of mitochondrial Reactive Oxygen Species (ROS) in Acute Myeloid Leukemia (AML), suggesting that increasing oxidative stress in blood malignant cells may be a successful therapeutic strategy in AML. After being awarded a K99 Pathway to Independence award from the National Institute of Health, she is now characterizing and targeting metabolic abnormalities that support AML.