Stephen R. Quake Howard Hughes Medical Institute Biography Publications Institution JoVE Articles Stephen R. Quake has not added a biography. If you are Stephen R. Quake and would like to personalize this page please email our Author Liaison for assistance. Publications Nature. Jul, 2012 | Pubmed ID: 22763444 Lab on a Chip. Jun, 2012 | Pubmed ID: 22714259 Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines PloS One. 2012 | Pubmed ID: 22586443 Lab on a Chip. Jun, 2012 | Pubmed ID: 22566096 Microfluidic Single-cell Real-time PCR for Comparative Analysis of Gene Expression Patterns Nature Protocols. May, 2012 | Pubmed ID: 22481529 Single-cell Sequencing Provides Clues About the Host Interactions of Segmented Filamentous Bacteria (SFB) Genome Research. Jun, 2012 | Pubmed ID: 22434425 Circulation. Feb, 2012 | Pubmed ID: 22354974 Identification of a Ckit+ Colonic Crypt Base Secretory Cell That Supports Lgr5+ Stem Cells in Mice Gastroenterology. Feb, 2012 | Pubmed ID: 22333952 Digital PCR Provides Absolute Quantitation of Viral Load for an Occult RNA Virus Journal of Virological Methods. Jan, 2012 | Pubmed ID: 21983150 The Plant Cell. Dec, 2011 | Pubmed ID: 22186371 Single-cell Dissection of Transcriptional Heterogeneity in Human Colon Tumors Nature Biotechnology. Dec, 2011 | Pubmed ID: 22081019 Tracking Single Hematopoietic Stem Cells in Vivo Using High-throughput Sequencing in Conjunction with Viral Genetic Barcoding Nature Biotechnology. Oct, 2011 | Pubmed ID: 21964413 Genomic Analysis at the Single-cell Level Annual Review of Genetics. 2011 | Pubmed ID: 21942365 Partial Genome Assembly for a Candidate Division OP11 Single Cell from an Anoxic Spring (Zodletone Spring, Oklahoma) Applied and Environmental Microbiology. Nov, 2011 | Pubmed ID: 21908640 The Genomic Sequence of the Chinese Hamster Ovary (CHO)-K1 Cell Line Nature Biotechnology. Aug, 2011 | Pubmed ID: 21804562 Dynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging-related Transcriptional Networks PLoS Genetics. Jun, 2011 | Pubmed ID: 21738489 An Information Theoretic, Microfluidic-based Single Cell Analysis Permits Identification of Subpopulations Among Putatively Homogeneous Stem Cells PloS One. 2011 | Pubmed ID: 21731674 Nature Methods. Apr, 2011 | Pubmed ID: 21451520 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21444804 Determinism and Stochasticity During Maturation of the Zebrafish Antibody Repertoire Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21393572 Nature Medicine. Mar, 2011 | Pubmed ID: 21383717 Genome of a Low-salinity Ammonia-oxidizing Archaeon Determined by Single-cell and Metagenomic Analysis PloS One. 2011 | Pubmed ID: 21364937 Nature Methods. Mar, 2011 | Pubmed ID: 21297618 Nature Biotechnology. Jan, 2011 | Pubmed ID: 21170043 Digital MDA for Enumeration of Total Nucleic Acid Contamination Nucleic Acids Research. Mar, 2011 | Pubmed ID: 21071419 Biophysical Journal. Oct, 2010 | Pubmed ID: 20959081 Analytical Chemistry. Oct, 2010 | Pubmed ID: 20936785 De Novo Identification and Biophysical Characterization of Transcription-factor Binding Sites with Microfluidic Affinity Analysis Nature Biotechnology. Sep, 2010 | Pubmed ID: 20802496 Nature. Jul, 2010 | Pubmed ID: 20581820 Clinical Chemistry. Aug, 2010 | Pubmed ID: 20558635 Physical Review Letters. Apr, 2010 | Pubmed ID: 20482145 PloS One. 2010 | Pubmed ID: 20454671 Lancet. May, 2010 | Pubmed ID: 20435227 Nucleic Acids Research. May, 2010 | Pubmed ID: 20176572 Nature Nanotechnology. Feb, 2010 | Pubmed ID: 20023643 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 19906998 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19841254 Applied Physics Letters. Aug, 2009 | Pubmed ID: 19777091 Nature Biotechnology. Sep, 2009 | Pubmed ID: 19668243 High-throughput Sequencing of the Zebrafish Antibody Repertoire Science (New York, N.Y.). May, 2009 | Pubmed ID: 19423829 Automated Microfluidic Chromatin Immunoprecipitation from 2,000 Cells Lab on a Chip. May, 2009 | Pubmed ID: 19417902 American Journal of Obstetrics and Gynecology. May, 2009 | Pubmed ID: 19375573 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2009 | Pubmed ID: 19301395 Digital PCR Provides Sensitive and Absolute Calibration for High Throughput Sequencing BMC Genomics. 2009 | Pubmed ID: 19298667 Association of Reactive Oxygen Species Levels and Radioresistance in Cancer Stem Cells Nature. Apr, 2009 | Pubmed ID: 19194462 An in Vitro Microfluidic Approach to Generating Protein-interaction Networks Nature Methods. Jan, 2009 | Pubmed ID: 19098921 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18838674 Discovery of a Hepatitis C Target and Its Pharmacological Inhibitors by Microfluidic Affinity Analysis Nature Biotechnology. Sep, 2008 | Pubmed ID: 18758449 A Synthetic Escherichia Coli Predator-prey Ecosystem Molecular Systems Biology. 2008 | Pubmed ID: 18414488 Single-molecule DNA Sequencing of a Viral Genome Science (New York, N.Y.). Apr, 2008 | Pubmed ID: 18388294 Lab on a Chip. Jan, 2008 | Pubmed ID: 18094763 Journal of Applied Physics. 2007 | Pubmed ID: 19381353 Versatile, Fully Automated, Microfluidic Cell Culture System Analytical Chemistry. Nov, 2007 | Pubmed ID: 17953452 Transcriptional Instability is Not a Universal Attribute of Aging Aging Cell. Dec, 2007 | Pubmed ID: 17925006 Nanoliter Reactors Improve Multiple Displacement Amplification of Genomes from Single Cells PLoS Genetics. Sep, 2007 | Pubmed ID: 17892324 Analytical Chemistry. Oct, 2007 | Pubmed ID: 17715994 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17620602 Biochemistry. May, 2007 | Pubmed ID: 17441732 Annual Review of Biophysics and Biomolecular Structure. 2007 | Pubmed ID: 17269901 Science (New York, N.Y.). Jan, 2007 | Pubmed ID: 17218526 Lab on a Chip. Jan, 2007 | Pubmed ID: 17180201 Physical Review Letters. Dec, 2006 | Pubmed ID: 17280412 Microfluidic Digital PCR Enables Multigene Analysis of Individual Environmental Bacteria Science (New York, N.Y.). Dec, 2006 | Pubmed ID: 17138901 Transcription Factor Profiling in Individual Hematopoietic Progenitors by Digital RT-PCR Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17098862 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17075056 Nature. Jul, 2006 | Pubmed ID: 16871205 Analytical Chemistry. May, 2006 | Pubmed ID: 16642997 Physical Review Letters. Mar, 2006 | Pubmed ID: 16606228 Journal of the American Chemical Society. Mar, 2006 | Pubmed ID: 16522084 BioTechniques. Jan, 2006 | Pubmed ID: 16454045 Analytical Chemistry. Feb, 2006 | Pubmed ID: 16448074 Nucleosides, Nucleotides & Nucleic Acids. 2006 | Pubmed ID: 16440981 Science (New York, N.Y.). Dec, 2005 | Pubmed ID: 16357255 Chemical Communications (Cambridge, England). Sep, 2005 | Pubmed ID: 16158111 Long-term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat Science (New York, N.Y.). Jul, 2005 | Pubmed ID: 15994559 Physical Review Letters. Oct, 2004 | Pubmed ID: 15525147 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004 | Pubmed ID: 15452343 Nucleic Acids Research. 2004 | Pubmed ID: 15155856 A Microfluidic Rectifier: Anisotropic Flow Resistance at Low Reynolds Numbers Physical Review Letters. Mar, 2004 | Pubmed ID: 15089471 Nature Biotechnology. Apr, 2004 | Pubmed ID: 15024389 Journal of the American Chemical Society. Mar, 2004 | Pubmed ID: 14982433 Physical Review Letters. Dec, 2003 | Pubmed ID: 14754067 Analytical Chemistry. Sep, 2003 | Pubmed ID: 14674446 Current Opinion in Structural Biology. Oct, 2003 | Pubmed ID: 14568607 Nature Biotechnology. Oct, 2003 | Pubmed ID: 14520403 Genome Research. Oct, 2003 | Pubmed ID: 12975313 Microfluidic Memory and Control Devices Science (New York, N.Y.). May, 2003 | Pubmed ID: 12738857 BioTechniques. Mar, 2003 | Pubmed ID: 12661156 Sequence Information Can Be Obtained from Single DNA Molecules Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12651960 Biophysical Journal. Feb, 2003 | Pubmed ID: 12547808 A Robust and Scalable Microfluidic Metering Method That Allows Protein Crystal Growth by Free Interface Diffusion Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12486223 Number, Density, and Surface/cytoplasmic Distribution of GABA Transporters at Presynaptic Structures of Knock-in Mice Carrying GABA Transporter Subtype 1-green Fluorescent Protein Fusions The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2002 | Pubmed ID: 12451126 Identification and Confirmation of a Module of Coexpressed Genes Genome Research. Oct, 2002 | Pubmed ID: 12368243 Science (New York, N.Y.). Oct, 2002 | Pubmed ID: 12351675 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12235357 Electrophoresis. Aug, 2002 | Pubmed ID: 12210169 An Integrated Microfabricated Cell Sorter Analytical Chemistry. Jun, 2002 | Pubmed ID: 12069222 Genome Research. Jan, 2002 | Pubmed ID: 11779839 Time-lapse fluorescensimagografi af Arabidopsis rodvækst med Rapid Manipulation af The Root miljøet ved hjælp af RootChip Guido Grossmann1, Matthias Meier2,3,4, Heather N. Cartwright1, Davide Sosso1, Stephen R. Quake2,3, David W. Ehrhardt1, Wolf B. Frommer1 1Department of Plant Biology, Carnegie Institution for Science, 2Howard Hughes Medical Institute, 3Departments of Applied Physics and Bioengineering, Stanford University, 4Department of Microsystems Engineering (IMTEK) and Center for Biological Signaling Studies (BIOSS), University of Freiburg JoVE 4290 Bioengineering
Time-lapse fluorescensimagografi af Arabidopsis rodvækst med Rapid Manipulation af The Root miljøet ved hjælp af RootChip Guido Grossmann1, Matthias Meier2,3,4, Heather N. Cartwright1, Davide Sosso1, Stephen R. Quake2,3, David W. Ehrhardt1, Wolf B. Frommer1 1Department of Plant Biology, Carnegie Institution for Science, 2Howard Hughes Medical Institute, 3Departments of Applied Physics and Bioengineering, Stanford University, 4Department of Microsystems Engineering (IMTEK) and Center for Biological Signaling Studies (BIOSS), University of Freiburg JoVE 4290 Bioengineering
