Stephen R. Quake Howard Hughes Medical Institute Biography Publications Institution JoVE Articles Stephen R. Quake has not added a biography. If you are Stephen R. Quake and would like to personalize this page please email our Author Liaison for assistance. Publications Nature. Jul, 2012 | Pubmed ID: 22763444 Lab on a Chip. Jun, 2012 | Pubmed ID: 22714259 Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines PloS One. 2012 | Pubmed ID: 22586443 Lab on a Chip. Jun, 2012 | Pubmed ID: 22566096 Microfluidic Single-cell Real-time PCR for Comparative Analysis of Gene Expression Patterns Nature Protocols. May, 2012 | Pubmed ID: 22481529 Single-cell Sequencing Provides Clues About the Host Interactions of Segmented Filamentous Bacteria (SFB) Genome Research. Jun, 2012 | Pubmed ID: 22434425 Circulation. Feb, 2012 | Pubmed ID: 22354974 Identification D'un Ckit + Colique Crypte Base Cellule Sécrétrice Qui Supporte Lgr5 + Tige Cellules Chez La Souris Gastroenterology. Feb, 2012 | Pubmed ID: 22333952 PCR Numérique Fournit La Quantification Absolue De La Charge Virale D'un Virus à ARN Occulte Journal of Virological Methods. Jan, 2012 | Pubmed ID: 21983150 The Plant Cell. Dec, 2011 | Pubmed ID: 22186371 Dissection Unicellulaire De Transcriptional Hétérogénéité Dans Les Tumeurs Du Côlon Humain Nature Biotechnology. Dec, 2011 | Pubmed ID: 22081019 Suivi Unique De Cellules Souches Hématopoïétiques in Vivo Par Séquençage Haut-débit En Conjonction Avec Code-barres Génétique Virale Nature Biotechnology. Oct, 2011 | Pubmed ID: 21964413 Genomic Analysis at the Single-cell Level Annual Review of Genetics. 2011 | Pubmed ID: 21942365 Partial Genome Assembly for a Candidate Division OP11 Single Cell from an Anoxic Spring (Zodletone Spring, Oklahoma) Applied and Environmental Microbiology. Nov, 2011 | Pubmed ID: 21908640 La Séquence Génomique De L'ovaire De Hamster Chinois (CHO)-ligne De Cellule K1 Nature Biotechnology. Aug, 2011 | Pubmed ID: 21804562 Localisation Chromatine Dynamique De Sirt6 Formes Stress Et Liées Au Vieillissement Réseaux Transcriptionnels PLoS Genetics. Jun, 2011 | Pubmed ID: 21738489 Une Analyse Théorique, Axée Sur La Microfluidique Monocellulaire D'informations Permet L'identification Des Sous-populations Parmi Putativement Homogènes De Cellules Souches PloS One. 2011 | Pubmed ID: 21731674 Nature Methods. Apr, 2011 | Pubmed ID: 21451520 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21444804 Déterminisme Et Aléatoire Au Cours De La Maturation Du Répertoire Anticorps Zebrafish Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21393572 Nature Medicine. Mar, 2011 | Pubmed ID: 21383717 Genome of a Low-salinity Ammonia-oxidizing Archaeon Determined by Single-cell and Metagenomic Analysis PloS One. 2011 | Pubmed ID: 21364937 Nature Methods. Mar, 2011 | Pubmed ID: 21297618 Nature Biotechnology. Jan, 2011 | Pubmed ID: 21170043 Digital MDA for Enumeration of Total Nucleic Acid Contamination Nucleic Acids Research. Mar, 2011 | Pubmed ID: 21071419 Biophysical Journal. Oct, 2010 | Pubmed ID: 20959081 Analytical Chemistry. Oct, 2010 | Pubmed ID: 20936785 De Novo Identification Et Caractérisation Biophysique Des Sites De Liaison Du Facteur De Transcription Analyse Des Affinités Microfluidique Nature Biotechnology. Sep, 2010 | Pubmed ID: 20802496 Nature. Jul, 2010 | Pubmed ID: 20581820 Clinical Chemistry. Aug, 2010 | Pubmed ID: 20558635 Physical Review Letters. Apr, 2010 | Pubmed ID: 20482145 PloS One. 2010 | Pubmed ID: 20454671 Lancet. May, 2010 | Pubmed ID: 20435227 Nucleic Acids Research. May, 2010 | Pubmed ID: 20176572 Nature Nanotechnology. Feb, 2010 | Pubmed ID: 20023643 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 19906998 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19841254 Applied Physics Letters. Aug, 2009 | Pubmed ID: 19777091 Nature Biotechnology. Sep, 2009 | Pubmed ID: 19668243 Séquençage Haut-débit Du Répertoire Anticorps Zebrafish Science (New York, N.Y.). May, 2009 | Pubmed ID: 19423829 Immunoprécipitation De Chromatine Microfluidique Automatisé De 2 000 Cellules Lab on a Chip. May, 2009 | Pubmed ID: 19417902 American Journal of Obstetrics and Gynecology. May, 2009 | Pubmed ID: 19375573 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2009 | Pubmed ID: 19301395 PCR Numérique Fournit étalonnage Absolu Et Sensible Pour Le Séquençage à Haut Débit BMC Genomics. 2009 | Pubmed ID: 19298667 Association of Reactive Oxygen Species Levels and Radioresistance in Cancer Stem Cells Nature. Apr, 2009 | Pubmed ID: 19194462 Une Approche in Vitro Microfluidique Générant Des Réseaux D'interaction De La Protéine Nature Methods. Jan, 2009 | Pubmed ID: 19098921 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18838674 Découverte D'une Cible De L'hépatite C Et Ses Inhibiteurs Pharmacologiques Par Analyse Des Affinités Microfluidique Nature Biotechnology. Sep, 2008 | Pubmed ID: 18758449 Un Coli Synthétique Escherichia Prédateurs-proies Des écosystèmes Molecular Systems Biology. 2008 | Pubmed ID: 18414488 Séquençage De L'ADN Simple-molécule D'un Génome Viral Science (New York, N.Y.). Apr, 2008 | Pubmed ID: 18388294 Lab on a Chip. Jan, 2008 | Pubmed ID: 18094763 Journal of Applied Physics. 2007 | Pubmed ID: 19381353 Polyvalent, Entièrement Automatisé, Système Microfluidique Culture Cellulaire Analytical Chemistry. Nov, 2007 | Pubmed ID: 17953452 Transcriptional Instability is Not a Universal Attribute of Aging Aging Cell. Dec, 2007 | Pubmed ID: 17925006 Nanolitre Réacteurs Améliorent Plusieurs Amplification De Déplacement Des Génomes De Cellules Individuelles PLoS Genetics. Sep, 2007 | Pubmed ID: 17892324 Analytical Chemistry. Oct, 2007 | Pubmed ID: 17715994 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17620602 Biochemistry. May, 2007 | Pubmed ID: 17441732 Annual Review of Biophysics and Biomolecular Structure. 2007 | Pubmed ID: 17269901 Science (New York, N.Y.). Jan, 2007 | Pubmed ID: 17218526 Lab on a Chip. Jan, 2007 | Pubmed ID: 17180201 Physical Review Letters. Dec, 2006 | Pubmed ID: 17280412 Microfluidique Numérique PCR Permet L'analyse Multigénique Des Individuels Bactéries De L'environnement Science (New York, N.Y.). Dec, 2006 | Pubmed ID: 17138901 Transcription Factor Profiling in Individual Hematopoietic Progenitors by Digital RT-PCR Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17098862 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17075056 Nature. Jul, 2006 | Pubmed ID: 16871205 Analytical Chemistry. May, 2006 | Pubmed ID: 16642997 Physical Review Letters. Mar, 2006 | Pubmed ID: 16606228 Journal of the American Chemical Society. Mar, 2006 | Pubmed ID: 16522084 BioTechniques. Jan, 2006 | Pubmed ID: 16454045 Analytical Chemistry. Feb, 2006 | Pubmed ID: 16448074 Nucleosides, Nucleotides & Nucleic Acids. 2006 | Pubmed ID: 16440981 Science (New York, N.Y.). Dec, 2005 | Pubmed ID: 16357255 Chemical Communications (Cambridge, England). Sep, 2005 | Pubmed ID: 16158111 Surveillance à Long Terme Des Bactéries Subissant Le Contrôle Des Populations Programmée Dans Un Microchemostat Science (New York, N.Y.). Jul, 2005 | Pubmed ID: 15994559 Physical Review Letters. Oct, 2004 | Pubmed ID: 15525147 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004 | Pubmed ID: 15452343 Nucleic Acids Research. 2004 | Pubmed ID: 15155856 Un Redresseur De Microfluidique : Résistance à L'écoulement Anisotropes à Faible Nombre De Reynolds Physical Review Letters. Mar, 2004 | Pubmed ID: 15089471 Nature Biotechnology. Apr, 2004 | Pubmed ID: 15024389 Journal of the American Chemical Society. Mar, 2004 | Pubmed ID: 14982433 Physical Review Letters. Dec, 2003 | Pubmed ID: 14754067 Analytical Chemistry. Sep, 2003 | Pubmed ID: 14674446 Current Opinion in Structural Biology. Oct, 2003 | Pubmed ID: 14568607 Nature Biotechnology. Oct, 2003 | Pubmed ID: 14520403 Genome Research. Oct, 2003 | Pubmed ID: 12975313 Dispositifs De Contrôle Et De La Mémoire De Microfluidique Science (New York, N.Y.). May, 2003 | Pubmed ID: 12738857 BioTechniques. Mar, 2003 | Pubmed ID: 12661156 Informations Sur Les Séquences Peuvent être Obtenues à Des Molécules D'ADN Unique Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12651960 Biophysical Journal. Feb, 2003 | Pubmed ID: 12547808 Une Méthode De Mesure Robuste Et évolutive Microfluidique Qui Permet La Croissance Des Cristaux De Protéines Par Diffusion Interface Gratuit Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12486223 Number, Density, and Surface/cytoplasmic Distribution of GABA Transporters at Presynaptic Structures of Knock-in Mice Carrying GABA Transporter Subtype 1-green Fluorescent Protein Fusions The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2002 | Pubmed ID: 12451126 L'identification Et La Confirmation D'un Module De Gènes Dynorphin Genome Research. Oct, 2002 | Pubmed ID: 12368243 Science (New York, N.Y.). Oct, 2002 | Pubmed ID: 12351675 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12235357 Electrophoresis. Aug, 2002 | Pubmed ID: 12210169 Un Trieur De Cellules Intégré Microfabriqué Analytical Chemistry. Jun, 2002 | Pubmed ID: 12069222 Genome Research. Jan, 2002 | Pubmed ID: 11779839 Time-lapse d'imagerie par fluorescence de la croissance racinaire d'Arabidopsis avec la manipulation rapide de l'environnement root en utilisant le RootChip Guido Grossmann1, Matthias Meier2,3,4, Heather N. Cartwright1, Davide Sosso1, Stephen R. Quake2,3, David W. Ehrhardt1, Wolf B. Frommer1 1Department of Plant Biology, Carnegie Institution for Science, 2Howard Hughes Medical Institute, 3Departments of Applied Physics and Bioengineering, Stanford University, 4Department of Microsystems Engineering (IMTEK) and Center for Biological Signaling Studies (BIOSS), University of Freiburg JoVE 4290 Bioengineering
Time-lapse d'imagerie par fluorescence de la croissance racinaire d'Arabidopsis avec la manipulation rapide de l'environnement root en utilisant le RootChip Guido Grossmann1, Matthias Meier2,3,4, Heather N. Cartwright1, Davide Sosso1, Stephen R. Quake2,3, David W. Ehrhardt1, Wolf B. Frommer1 1Department of Plant Biology, Carnegie Institution for Science, 2Howard Hughes Medical Institute, 3Departments of Applied Physics and Bioengineering, Stanford University, 4Department of Microsystems Engineering (IMTEK) and Center for Biological Signaling Studies (BIOSS), University of Freiburg JoVE 4290 Bioengineering