Stephen R. Quake Howard Hughes Medical Institute Biography Publications Institution JoVE Articles Stephen R. Quake has not added a biography. If you are Stephen R. Quake and would like to personalize this page please email our Author Liaison for assistance. Publications Nature. Jul, 2012 | Pubmed ID: 22763444 Lab on a Chip. Jun, 2012 | Pubmed ID: 22714259 Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines PloS One. 2012 | Pubmed ID: 22586443 Lab on a Chip. Jun, 2012 | Pubmed ID: 22566096 Microfluidic Single-cell Real-time PCR for Comparative Analysis of Gene Expression Patterns Nature Protocols. May, 2012 | Pubmed ID: 22481529 Single-cell Sequencing Provides Clues About the Host Interactions of Segmented Filamentous Bacteria (SFB) Genome Research. Jun, 2012 | Pubmed ID: 22434425 Circulation. Feb, 2012 | Pubmed ID: 22354974 Kennung Einer Ckit + Kolon Crypt Base Sekretorischen Zelle, Die Bei Mäusen Unterstützt Lgr5 + Stem Cells Gastroenterology. Feb, 2012 | Pubmed ID: 22333952 Digitale PCR Bietet Absolute Quantitative Bestimmung Der Viruslast Für Eine Okkulte RNA-Virus Journal of Virological Methods. Jan, 2012 | Pubmed ID: 21983150 The Plant Cell. Dec, 2011 | Pubmed ID: 22186371 Einzeller-Dissektion Transkriptionelle Heterogenität Im Menschlichen Doppelpunkt Tumoren Nature Biotechnology. Dec, 2011 | Pubmed ID: 22081019 Verfolgen Einzelne Hämatopoetische Stammzellen, Die in Vivo Mit Hohem Durchsatz Sequenzierung in Verbindung Mit Viralen Genetische Barcoding Nature Biotechnology. Oct, 2011 | Pubmed ID: 21964413 Genomic Analysis at the Single-cell Level Annual Review of Genetics. 2011 | Pubmed ID: 21942365 Partial Genome Assembly for a Candidate Division OP11 Single Cell from an Anoxic Spring (Zodletone Spring, Oklahoma) Applied and Environmental Microbiology. Nov, 2011 | Pubmed ID: 21908640 Der Genomischen Sequenz Des Chinesischen Hamsters (CHO) Eierstock-K1 Zelllinie Nature Biotechnology. Aug, 2011 | Pubmed ID: 21804562 Dynamische Chromatin-Lokalisierung Von Sirt6 Formt Und Alterung-stressbedingten Transkriptionelle Netzwerke PLoS Genetics. Jun, 2011 | Pubmed ID: 21738489 Eine Theoretische, Microfluidic Basierende Einzelzelle Informationsanalyse Ermöglicht Identifikation Von Subpopulationen Unter Vermeintlich Homogenen Stammzellen PloS One. 2011 | Pubmed ID: 21731674 Nature Methods. Apr, 2011 | Pubmed ID: 21451520 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21444804 Determinismus Und Stochasticity Während Der Reifung Der Zebrafisch-Antikörper-Repertoire Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21393572 Nature Medicine. Mar, 2011 | Pubmed ID: 21383717 Genome of a Low-salinity Ammonia-oxidizing Archaeon Determined by Single-cell and Metagenomic Analysis PloS One. 2011 | Pubmed ID: 21364937 Nature Methods. Mar, 2011 | Pubmed ID: 21297618 Nature Biotechnology. Jan, 2011 | Pubmed ID: 21170043 Digital MDA for Enumeration of Total Nucleic Acid Contamination Nucleic Acids Research. Mar, 2011 | Pubmed ID: 21071419 Biophysical Journal. Oct, 2010 | Pubmed ID: 20959081 Analytical Chemistry. Oct, 2010 | Pubmed ID: 20936785 De-Novo-Identifikation Und Biophysikalische Charakterisierung Von Transkriptionsfaktor Bindungsstellen Mit Mikrofluidische Affinität Analyse Nature Biotechnology. Sep, 2010 | Pubmed ID: 20802496 Nature. Jul, 2010 | Pubmed ID: 20581820 Clinical Chemistry. Aug, 2010 | Pubmed ID: 20558635 Physical Review Letters. Apr, 2010 | Pubmed ID: 20482145 PloS One. 2010 | Pubmed ID: 20454671 Lancet. May, 2010 | Pubmed ID: 20435227 Nucleic Acids Research. May, 2010 | Pubmed ID: 20176572 Nature Nanotechnology. Feb, 2010 | Pubmed ID: 20023643 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 19906998 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19841254 Applied Physics Letters. Aug, 2009 | Pubmed ID: 19777091 Nature Biotechnology. Sep, 2009 | Pubmed ID: 19668243 Hochdurchsatz-Sequenzierung Der Zebrafisch-Antikörper-Repertoire Science (New York, N.Y.). May, 2009 | Pubmed ID: 19423829 Automatisierte Mikrofluidische Chromatin Immunopräzipitation Aus 2.000 Zellen Lab on a Chip. May, 2009 | Pubmed ID: 19417902 American Journal of Obstetrics and Gynecology. May, 2009 | Pubmed ID: 19375573 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2009 | Pubmed ID: 19301395 Digitale PCR Stellt Sensible Und Absolute Kalibrierung Für Hochdurchsatz-Sequenzierung BMC Genomics. 2009 | Pubmed ID: 19298667 Association of Reactive Oxygen Species Levels and Radioresistance in Cancer Stem Cells Nature. Apr, 2009 | Pubmed ID: 19194462 Ein In-vitro Microfluidic-Ansatz Für Die Erzeugung Von Protein-Interaktion Netze Nature Methods. Jan, 2009 | Pubmed ID: 19098921 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18838674 Entdeckung Einer Hepatitis-C-Ziel Und Seine Pharmakologischen Inhibitoren Mikrofluidische Affinität Analyse Nature Biotechnology. Sep, 2008 | Pubmed ID: 18758449 Ein Synthetisches Escherichia Coli-Räuber-Beute-Ökosystem Molecular Systems Biology. 2008 | Pubmed ID: 18414488 Einzelmolekül-DNA-Sequenzierung Eines Viralen Genoms Science (New York, N.Y.). Apr, 2008 | Pubmed ID: 18388294 Lab on a Chip. Jan, 2008 | Pubmed ID: 18094763 Journal of Applied Physics. 2007 | Pubmed ID: 19381353 Vielseitig, Vollautomatische, Microfluidic Zellkultursystem Analytical Chemistry. Nov, 2007 | Pubmed ID: 17953452 Transcriptional Instability is Not a Universal Attribute of Aging Aging Cell. Dec, 2007 | Pubmed ID: 17925006 Nanoliter Reaktoren Verbessern Mehrere Verschiebung Verstärkung Der Genome Von Einzelzellen PLoS Genetics. Sep, 2007 | Pubmed ID: 17892324 Analytical Chemistry. Oct, 2007 | Pubmed ID: 17715994 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17620602 Biochemistry. May, 2007 | Pubmed ID: 17441732 Annual Review of Biophysics and Biomolecular Structure. 2007 | Pubmed ID: 17269901 Science (New York, N.Y.). Jan, 2007 | Pubmed ID: 17218526 Lab on a Chip. Jan, 2007 | Pubmed ID: 17180201 Physical Review Letters. Dec, 2006 | Pubmed ID: 17280412 Mikrofluidische Digitale PCR Ermöglicht Multigene Analyse Des Individuellen ökologischen Bakterien Science (New York, N.Y.). Dec, 2006 | Pubmed ID: 17138901 Transcription Factor Profiling in Individual Hematopoietic Progenitors by Digital RT-PCR Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17098862 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17075056 Nature. Jul, 2006 | Pubmed ID: 16871205 Analytical Chemistry. May, 2006 | Pubmed ID: 16642997 Physical Review Letters. Mar, 2006 | Pubmed ID: 16606228 Journal of the American Chemical Society. Mar, 2006 | Pubmed ID: 16522084 BioTechniques. Jan, 2006 | Pubmed ID: 16454045 Analytical Chemistry. Feb, 2006 | Pubmed ID: 16448074 Nucleosides, Nucleotides & Nucleic Acids. 2006 | Pubmed ID: 16440981 Science (New York, N.Y.). Dec, 2005 | Pubmed ID: 16357255 Chemical Communications (Cambridge, England). Sep, 2005 | Pubmed ID: 16158111 Langzeit-Monitoring Von Bakterien, Die Programmiertem Bevölkerungskontrolle in Einem Microchemostat Science (New York, N.Y.). Jul, 2005 | Pubmed ID: 15994559 Physical Review Letters. Oct, 2004 | Pubmed ID: 15525147 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004 | Pubmed ID: 15452343 Nucleic Acids Research. 2004 | Pubmed ID: 15155856 Ein Mikrofluidischen Gleichrichter: Anisotropen Strömungswiderstand Bei Niedrigen Reynolds-Zahlen Physical Review Letters. Mar, 2004 | Pubmed ID: 15089471 Nature Biotechnology. Apr, 2004 | Pubmed ID: 15024389 Journal of the American Chemical Society. Mar, 2004 | Pubmed ID: 14982433 Physical Review Letters. Dec, 2003 | Pubmed ID: 14754067 Analytical Chemistry. Sep, 2003 | Pubmed ID: 14674446 Current Opinion in Structural Biology. Oct, 2003 | Pubmed ID: 14568607 Nature Biotechnology. Oct, 2003 | Pubmed ID: 14520403 Genome Research. Oct, 2003 | Pubmed ID: 12975313 Mikrofluidik-Speicher-und Steuereinrichtungen Science (New York, N.Y.). May, 2003 | Pubmed ID: 12738857 BioTechniques. Mar, 2003 | Pubmed ID: 12661156 Sequenzinformationen Erhalten Sie Bei Einzelner DNA-Moleküle Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12651960 Biophysical Journal. Feb, 2003 | Pubmed ID: 12547808 Eine Robuste Und Skalierbare Mikrofluidischen Messmethode, Die Proteinkristallwachstum Ermöglicht Durch Freie Diffusion Schnittstelle Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12486223 Number, Density, and Surface/cytoplasmic Distribution of GABA Transporters at Presynaptic Structures of Knock-in Mice Carrying GABA Transporter Subtype 1-green Fluorescent Protein Fusions The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2002 | Pubmed ID: 12451126 Identifizierung Und Bestätigung Eines Moduls Coexprimierten Gene Genome Research. Oct, 2002 | Pubmed ID: 12368243 Science (New York, N.Y.). Oct, 2002 | Pubmed ID: 12351675 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12235357 Electrophoresis. Aug, 2002 | Pubmed ID: 12210169 Ein Integrierter Mikrofabrizierten Zellsortierer Analytical Chemistry. Jun, 2002 | Pubmed ID: 12069222 Genome Research. Jan, 2002 | Pubmed ID: 11779839 Zeitraffer-Fluoreszenz-Imaging von Arabidopsis Wurzelwachstum mit Rapid Manipulation der Root-Umgebung mit dem RootChip Guido Grossmann1, Matthias Meier2,3,4, Heather N. Cartwright1, Davide Sosso1, Stephen R. Quake2,3, David W. Ehrhardt1, Wolf B. Frommer1 1Department of Plant Biology, Carnegie Institution for Science, 2Howard Hughes Medical Institute, 3Departments of Applied Physics and Bioengineering, Stanford University, 4Department of Microsystems Engineering (IMTEK) and Center for Biological Signaling Studies (BIOSS), University of Freiburg JoVE 4290 Bioengineering
Zeitraffer-Fluoreszenz-Imaging von Arabidopsis Wurzelwachstum mit Rapid Manipulation der Root-Umgebung mit dem RootChip Guido Grossmann1, Matthias Meier2,3,4, Heather N. Cartwright1, Davide Sosso1, Stephen R. Quake2,3, David W. Ehrhardt1, Wolf B. Frommer1 1Department of Plant Biology, Carnegie Institution for Science, 2Howard Hughes Medical Institute, 3Departments of Applied Physics and Bioengineering, Stanford University, 4Department of Microsystems Engineering (IMTEK) and Center for Biological Signaling Studies (BIOSS), University of Freiburg JoVE 4290 Bioengineering