Steven D. Goodman Center for Microbial Pathogenesis, Nationwide Children’s Hospital and the Department of Pediatrics The Ohio State University Biography Publications Institution JoVE Articles Steven D. Goodman has not added a biography. If you are Steven D. Goodman and would like to personalize this page please email our Author Liaison for assistance. Publications Bacterial Biofilms Utilize an Underlying Extracellular DNA Matrix Structure That Can Be Targeted for Biofilm Resolution Microorganisms. Feb, 2022 | Pubmed ID: 35208922 A Humanized Monoclonal Antibody Potentiates Killing of Diverse Biofilm-Forming Respiratory Tract Pathogens by Antibiotics Antimicrobial Agents and Chemotherapy. 03, 2022 | Pubmed ID: 35007137 The Extracellular Innate-immune Effector HMGB1 Limits Pathogenic Bacterial Biofilm Proliferation The Journal of Clinical Investigation. 08, 2021 | Pubmed ID: 34396989 in Its Biofilm State Improves Protection from Experimental Necrotizing Enterocolitis Nutrients. Mar, 2021 | Pubmed ID: 33809097 The Dental Plaque Biofilm Matrix Periodontology 2000. 06, 2021 | Pubmed ID: 33690911 Humanized Anti-DNABII Fab Fragments Plus Ofloxacin Eradicated Biofilms in Experimental Otitis Media The Laryngoscope. 10, 2021 | Pubmed ID: 33666254 Escherichia Coli Nissle 1917 Administered As a Dextranomar Microsphere Biofilm Enhances Immune Responses Against Human Rotavirus in a Neonatal Malnourished Pig Model Colonized with Human Infant Fecal Microbiota PloS One. 2021 | Pubmed ID: 33592026 Enhanced Biofilm and Extracellular Matrix Production by Chronic Carriage Versus Acute Isolates of Salmonella Typhi PLoS Pathogens. 01, 2021 | Pubmed ID: 33465146 Measurement of Uracil-DNA Glycosylase Activity by Matrix Assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Technique DNA Repair. 01, 2021 | Pubmed ID: 33254084 Nontypeable Newly Released (NRel) from Biofilms by Antibody-mediated Dispersal Antibody-mediated Disruption Are Phenotypically Distinct Biofilm. Dec, 2020 | Pubmed ID: 33447823 Targeting a Bacterial DNABII Protein with a Chimeric Peptide Immunogen or Humanised Monoclonal Antibody to Prevent or Treat Recalcitrant Biofilm-mediated Infections EBioMedicine. Sep, 2020 | Pubmed ID: 32651162 Immunization with a Biofilm-Disrupting Nontypeable Vaccine Antigen Did Not Alter the Gut Microbiome in Chinchillas, Unlike Oral Delivery of a Broad-Spectrum Antibiotic Commonly Used for Otitis Media MSphere. 04, 2020 | Pubmed ID: 32295873 Proofreading of Single Nucleotide Insertion/deletion Replication Errors Analyzed by MALDI-TOF Mass Spectrometry Assay DNA Repair. 04, 2020 | Pubmed ID: 32036259 Antibodies Against the DNABII Protein Integration Host Factor (IHF) Inhibit Sinus Implant Biofilms The Laryngoscope. 06, 2020 | Pubmed ID: 31314141 Identification of Essential Biofilm Proteins in Middle Ear Fluids of Otitis Media with Effusion Patients The Laryngoscope. 03, 2020 | Pubmed ID: 31021431 Application of Single Nucleotide Extension and MALDI-TOF Mass Spectrometry in Proofreading and DNA Repair Assay DNA Repair. 01, 2018 | Pubmed ID: 29223016 The DNABII Family of Proteins is Comprised of the Only Nucleoid Associated Proteins Required for Nontypeable Haemophilus Influenzae Biofilm Structure MicrobiologyOpen. Dec, 2017 | Pubmed ID: 29230970 Nontypeable Releases DNA and DNABII Proteins Via a T4SS-like Complex and ComE of the Type IV Pilus Machinery Proceedings of the National Academy of Sciences of the United States of America. 08, 2017 | Pubmed ID: 28696280 Transcutaneous Immunization with a Band-Aid Prevents Experimental Otitis Media in a Polymicrobial Model Clinical and Vaccine Immunology : CVI. Jun, 2017 | Pubmed ID: 28381402 Identification of Biofilms in Post-tympanostomy Tube Otorrhea The Laryngoscope. 08, 2016 | Pubmed ID: 27426942 Monoclonal Antibodies Against DNA-binding Tips of DNABII Proteins Disrupt Biofilms in Vitro and Induce Bacterial Clearance in Vivo EBioMedicine. Aug, 2016 | Pubmed ID: 27342872 DNABII Proteins Play a Central Role in UPEC Biofilm Structure Molecular Microbiology. Jun, 2015 | Pubmed ID: 25757804 Antibodies Against the Majority Subunit of Type IV Pili Disperse Nontypeable Haemophilus Influenzae Biofilms in a LuxS-dependent Manner and Confer Therapeutic Resolution of Experimental Otitis Media Molecular Microbiology. Apr, 2015 | Pubmed ID: 25597921 Evaluation of the Kinetics and Mechanism of Action of Anti-integration Host Factor-mediated Disruption of Bacterial Biofilms Molecular Microbiology. Sep, 2014 | Pubmed ID: 25069521 Structural Stability of Burkholderia Cenocepacia Biofilms is Reliant on EDNA Structure and Presence of a Bacterial Nucleic Acid Binding Protein PloS One. 2013 | Pubmed ID: 23799151 Antibodies Directed Against Integration Host Factor Mediate Biofilm Clearance from Nasopore The Laryngoscope. Nov, 2013 | Pubmed ID: 23670606 Targeting Bacterial Integration Host Factor to Disrupt Biofilms Associated with Cystic Fibrosis Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Jul, 2013 | Pubmed ID: 23168017 Aberrant Community Architecture and Attenuated Persistence of Uropathogenic Escherichia Coli in the Absence of Individual IHF Subunits PloS One. 2012 | Pubmed ID: 23133584 Biofilms Can Be Dispersed by Focusing the Immune System on a Common Family of Bacterial Nucleoid-associated Proteins Mucosal Immunology. Nov, 2011 | Pubmed ID: 21716265 The Extracellular DNA Lattice of Bacterial Biofilms is Structurally Related to Holliday Junction Recombination Intermediates Proceedings of the National Academy of Sciences of the United States of America. | Pubmed ID: 31767757 尿嘧啶-DNA糖基化酶测定，采用基质辅助激光解吸/电离飞行时间质谱分析 Hui-Lan Chang*1, Kang-Yi Su*1,2, Steven D. Goodman3, Wern-Cherng Cheng2, Liang-In Lin1,2, Ya-Chien Yang1,2, Sui-Yuan Chang1,2, Woei-horng Fang1,2 1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, 2Department of Laboratory Medicine, National Taiwan University Hospital, 3Center for Microbial Pathogenesis, Nationwide Children’s Hospital and the Department of Pediatrics, The Ohio State University JoVE 63089 Biochemistry 单核苷酸延长和 MALDI 质谱分析校对及 DNA 修复方法 Kang-Yi Su*1,2, Steven D. Goodman*3, Hung-Ming Lai1, Rong-Syuan Yen1, Wei-Yao Hu1, Wern-Cherng Cheng2, Liang-In Lin1,2, Ya-Chien Yang1,2, Woei-Horng Fang1,2 1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, 2Department of Laboratory Medicine, National Taiwan University Hospital, 3Center for Microbial Pathogenesis, Nationwide Children's Hospital and the Department of Pediatrics, The Ohio State University JoVE 57862 Biochemistry
尿嘧啶-DNA糖基化酶测定，采用基质辅助激光解吸/电离飞行时间质谱分析 Hui-Lan Chang*1, Kang-Yi Su*1,2, Steven D. Goodman3, Wern-Cherng Cheng2, Liang-In Lin1,2, Ya-Chien Yang1,2, Sui-Yuan Chang1,2, Woei-horng Fang1,2 1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, 2Department of Laboratory Medicine, National Taiwan University Hospital, 3Center for Microbial Pathogenesis, Nationwide Children’s Hospital and the Department of Pediatrics, The Ohio State University JoVE 63089 Biochemistry
单核苷酸延长和 MALDI 质谱分析校对及 DNA 修复方法 Kang-Yi Su*1,2, Steven D. Goodman*3, Hung-Ming Lai1, Rong-Syuan Yen1, Wei-Yao Hu1, Wern-Cherng Cheng2, Liang-In Lin1,2, Ya-Chien Yang1,2, Woei-Horng Fang1,2 1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, 2Department of Laboratory Medicine, National Taiwan University Hospital, 3Center for Microbial Pathogenesis, Nationwide Children's Hospital and the Department of Pediatrics, The Ohio State University JoVE 57862 Biochemistry
