Steven Mennerick Department of Psychiatry Washington University in St. Louis Biography Publications Institution JoVE Articles Steven Mennerick has not added a biography. If you are Steven Mennerick and would like to personalize this page please email our Author Liaison for assistance. Publications Crosstalk Between Synaptic Receptors Mediates NMDA-induced Suppression of Inhibition Journal of Neurophysiology. Jan, 2012 | Pubmed ID: 22279196 Neurosteroid Analogues. 17. Inverted Binding Orientations of Androsterone Enantiomers at the Steroid Potentiation Site on γ-Aminobutyric Acid Type A Receptors Journal of Medicinal Chemistry. Feb, 2012 | Pubmed ID: 22191644 Nicotinamide Mononucleotide Adenylyl Transferase 1 Protects Against Acute Neurodegeneration in Developing CNS by Inhibiting Excitotoxic-necrotic Cell Death Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22058226 Excitotoxicity Triggered by Neurobasal Culture Medium PloS One. 2011 | Pubmed ID: 21980512 Characteristics of α4/δ-containing Concatemeric GABA(A) Receptors Expressed in Xenopus Oocytes British Journal of Pharmacology. Sep, 2011 | Pubmed ID: 21950777 Presynaptically Silent Synapses: Dormancy and Awakening of Presynaptic Vesicle Release The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Sep, 2011 | Pubmed ID: 21908849 Don't Curse the Darkness, Light a Candle: Fluorescence Studies of Axon Excitability The Journal of Physiology. Sep, 2011 | Pubmed ID: 21885442 Presynaptic Silencing is an Endogenous Neuroprotectant During Excitotoxic Insults Neurobiology of Disease. Aug, 2011 | Pubmed ID: 21605675 Neurosteroid Analogues. 16. A New Explanation for the Lack of Anesthetic Effects of δ(16)-alphaxalone and Identification of a δ(17(20)) Analogue with Potent Anesthetic Activity Journal of Medicinal Chemistry. Jun, 2011 | Pubmed ID: 21504158 Calcium-independent Inhibitory G-protein Signaling Induces Persistent Presynaptic Muting of Hippocampal Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2011 | Pubmed ID: 21248122 Differential Effects of Axon Initial Segment and Somatodendritic GABAA Receptors on Excitability Measures in Rat Dentate Granule Neurons Journal of Neurophysiology. Jan, 2011 | Pubmed ID: 21068264 Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and GABAergic Actions of Alphaxalone, Δ16-alphaxalone and Their Corresponding 17-carbonitrile Analogues Bioorganic & Medicinal Chemistry Letters. Nov, 2010 | Pubmed ID: 20875742 Kinetic and Structural Determinants for GABA-A Receptor Potentiation by Neuroactive Steroids Current Neuropharmacology. Mar, 2010 | Pubmed ID: 20808543 Rapid Activation of Dormant Presynaptic Terminals by Phorbol Esters The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2010 | Pubmed ID: 20668189 Structurally Diverse Amphiphiles Exhibit Biphasic Modulation of GABAA Receptors: Similarities and Differences with Neurosteroid Actions British Journal of Pharmacology. May, 2010 | Pubmed ID: 20412070 The Sticky Issue of Neurosteroids and GABA(A) Receptors Trends in Neurosciences. Jul, 2010 | Pubmed ID: 20409596 Diverse Voltage-sensitive Dyes Modulate GABAA Receptor Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2010 | Pubmed ID: 20181584 A Synthetic 18-norsteroid Distinguishes Between Two Neuroactive Steroid Binding Sites on GABAA Receptors The Journal of Pharmacology and Experimental Therapeutics. May, 2010 | Pubmed ID: 20124410 Dynamic Modulation of Phasic and Asynchronous Glutamate Release in Hippocampal Synapses Journal of Neurophysiology. Jan, 2010 | Pubmed ID: 19889850 Axonal Sodium Channel Distribution Shapes the Depolarized Action Potential Threshold of Dentate Granule Neurons Hippocampus. Apr, 2010 | Pubmed ID: 19603521 Comparative Effects of Heterologous TRPV1 and TRPM8 Expression in Rat Hippocampal Neurons PloS One. 2009 | Pubmed ID: 19997638 Photodynamic Effects of Steroid-conjugated Fluorophores on GABAA Receptors Molecular Pharmacology. Oct, 2009 | Pubmed ID: 19596835 The Influence of Neuroactive Steroid Lipophilicity on GABAA Receptor Modulation: Evidence for a Low-affinity Interaction Journal of Neurophysiology. Aug, 2009 | Pubmed ID: 19553485 The Influence of the Membrane on Neurosteroid Actions at GABA(A) Receptors Psychoneuroendocrinology. Dec, 2009 | Pubmed ID: 19541427 Adenylyl Cyclases 1 and 8 Initiate a Presynaptic Homeostatic Response to Ethanol Treatment PloS One. 2009 | Pubmed ID: 19479030 NMDA Potentiation by Visible Light in the Presence of a Fluorescent Neurosteroid Analogue The Journal of Physiology. Jun, 2009 | Pubmed ID: 19403611 Dimethyl Sulfoxide (DMSO) Produces Widespread Apoptosis in the Developing Central Nervous System Neurobiology of Disease. Apr, 2009 | Pubmed ID: 19100327 High Threshold, Proximal Initiation, and Slow Conduction Velocity of Action Potentials in Dentate Granule Neuron Mossy Fibers Journal of Neurophysiology. Jul, 2008 | Pubmed ID: 18480368 A Specific Role for Ca2+-dependent Adenylyl Cyclases in Recovery from Adaptive Presynaptic Silencing The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2008 | Pubmed ID: 18480272 Endocytosis is Required for Synaptic Activity-dependent Release of Amyloid-beta in Vivo Neuron. Apr, 2008 | Pubmed ID: 18400162 Effects on Membrane Capacitance of Steroids with Antagonist Properties at GABAA Receptors Biophysical Journal. Jul, 2008 | Pubmed ID: 18339741 Neurosteroid Analogues. 14. Alternative Ring System Scaffolds: GABA Modulatory and Anesthetic Actions of Cyclopenta[b]phenanthrenes and Cyclopenta[b]anthracenes Journal of Medicinal Chemistry. Mar, 2008 | Pubmed ID: 18275132 Neurosteroid Analogues. 12. Potent Enhancement of GABA-mediated Chloride Currents at GABAA Receptors by Ent-androgens European Journal of Medicinal Chemistry. Jan, 2008 | Pubmed ID: 17434649 Vesicle Pool Heterogeneity at Hippocampal Glutamate and GABA Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2007 | Pubmed ID: 17855599 Astrocyte Membrane Responses and Potassium Accumulation During Neuronal Activity Hippocampus. 2007 | Pubmed ID: 17853441 Neurosteroid Migration to Intracellular Compartments Reduces Steroid Concentration in the Membrane and Diminishes GABA-A Receptor Potentiation The Journal of Physiology. Nov, 2007 | Pubmed ID: 17761771 Antagonism of Neurosteroid Modulation of Native Gamma-aminobutyric Acid Receptors by (3alpha,5alpha)-17-phenylandrost-16-en-3-ol European Journal of Pharmacology. Oct, 2007 | Pubmed ID: 17658511 Mechanisms of Neurosteroid Interactions with GABA(A) Receptors Pharmacology & Therapeutics. Oct, 2007 | Pubmed ID: 17524487 Anticonvulsant and Anesthetic Effects of a Fluorescent Neurosteroid Analog Activated by Visible Light Nature Neuroscience. Apr, 2007 | Pubmed ID: 17322875 Action Potential Initiation and Propagation in CA3 Pyramidal Axons Journal of Neurophysiology. May, 2007 | Pubmed ID: 17314237 A Spontaneous Tonic Chloride Conductance in Solitary Glutamatergic Hippocampal Neurons Brain Research. Nov, 2006 | Pubmed ID: 16987500 Linkage Between Cellular Communications, Energy Utilization, and Proliferation in Metastatic Neuroendocrine Cancers Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16895983 Neurosteroid Analogues. 11. Alternative Ring System Scaffolds: Gamma-aminobutyric Acid Receptor Modulation and Anesthetic Actions of Benz[f]indenes Journal of Medicinal Chemistry. Jul, 2006 | Pubmed ID: 16854065 Physiological Activity Depresses Synaptic Function Through an Effect on Vesicle Priming The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16775150 Homeostatic Regulation of Glutamate Release in Response to Depolarization Molecular Neurobiology. Apr, 2006 | Pubmed ID: 16603793 Synaptic Vesicles: Turning Reluctance into Action The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. Feb, 2006 | Pubmed ID: 16394189 Synaptic Activity Regulates Interstitial Fluid Amyloid-beta Levels in Vivo Neuron. Dec, 2005 | Pubmed ID: 16364896 Neurosteroid Access to the GABAA Receptor The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2005 | Pubmed ID: 16354918 An Integrated Functional Genomics and Metabolomics Approach for Defining Poor Prognosis in Human Neuroendocrine Cancers Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 15998737 Reluctant Vesicles Coaxed into the Limelight Neuron. May, 2005 | Pubmed ID: 15944119 Action Potential Fidelity During Normal and Epileptiform Activity in Paired Soma-axon Recordings from Rat Hippocampus The Journal of Physiology. Jul, 2005 | Pubmed ID: 15890699 Reluctant Vesicles Contribute to the Total Readily Releasable Pool in Glutamatergic Hippocampal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2005 | Pubmed ID: 15829636 Neurosteroid Analogues. 10. The Effect of Methyl Group Substitution at the C-6 and C-7 Positions on the GABA Modulatory and Anesthetic Actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one Journal of Medicinal Chemistry. Apr, 2005 | Pubmed ID: 15828844 New Evidence That Both T-type Calcium Channels and GABAA Channels Are Responsible for the Potent Peripheral Analgesic Effects of 5alpha-reduced Neuroactive Steroids Pain. Apr, 2005 | Pubmed ID: 15777868 Calcium-stimulated Adenylyl Cyclases Modulate Ethanol-induced Neurodegeneration in the Neonatal Brain The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15745964 Slow Actions of Neuroactive Steroids at GABAA Receptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2004 | Pubmed ID: 15282269 Plastic Elimination of Functional Glutamate Release Sites by Depolarization Neuron. May, 2004 | Pubmed ID: 15134639 Selective Antagonism of 5alpha-reduced Neurosteroid Effects at GABA(A) Receptors Molecular Pharmacology. May, 2004 | Pubmed ID: 15102947 Selective Effects of Potassium Elevations on Glutamate Signaling and Action Potential Conduction in Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2004 | Pubmed ID: 14715952 Neuroactive Steroid Interactions with Voltage-dependent Anion Channels: Lack of Relationship to GABA(A) Receptor Modulation and Anesthesia The Journal of Pharmacology and Experimental Therapeutics. Feb, 2004 | Pubmed ID: 14593090 Neurosteroid Analogues. 9. Conformationally Constrained Pregnanes: Structure-activity Studies of 13,24-cyclo-18,21-dinorcholane Analogues of the GABA Modulatory and Anesthetic Steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one Journal of Medicinal Chemistry. Dec, 2003 | Pubmed ID: 14640542 Activation-dependent Properties of Pregnenolone Sulfate Inhibition of GABAA Receptor-mediated Current The Journal of Physiology. Aug, 2003 | Pubmed ID: 12938673 Impaired Glial Glutamate Transport in a Mouse Tuberous Sclerosis Epilepsy Model Annals of Neurology. Aug, 2003 | Pubmed ID: 12891680 Homeostatic Effects of Depolarization on Ca2+ Influx, Synaptic Signaling, and Survival The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2003 | Pubmed ID: 12629186 Photoaffinity Labeling with a Neuroactive Steroid Analogue. 6-azi-pregnanolone Labels Voltage-dependent Anion Channel-1 in Rat Brain The Journal of Biological Chemistry. Apr, 2003 | Pubmed ID: 12560326 Feeding Hungry Neurons: Astrocytes Deliver Food for Thought Neuron. Jan, 2003 | Pubmed ID: 12546812 Ethanol-induced Death of Postnatal Hippocampal Neurons Neurobiology of Disease. Aug, 2002 | Pubmed ID: 12270700 3beta -hydroxypregnane Steroids Are Pregnenolone Sulfate-like GABA(A) Receptor Antagonists The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002 | Pubmed ID: 11978813 Contribution of Presynaptic Na(+) Channel Inactivation to Paired-pulse Synaptic Depression in Cultured Hippocampal Neurons Journal of Neurophysiology. Feb, 2002 | Pubmed ID: 11826057 प्रतिगामी फ्लोरोसेंट लेबलिंग पहचाने गए न्यूरॉन्स से लक्षित कोशिकी एकल इकाई रिकॉर्डिंग के लिए अनुमति देता है Ariel M. Lyons-Warren1, Tsunehiko Kohashi1,2, Steven Mennerick3, Bruce A. Carlson1 1Department of Biology, Washington University in St. Louis, 2Division of Biological Science, Graduate School of Science, Nagoya University, 3Department of Psychiatry, Washington University in St. Louis JoVE 3921 Neuroscience Presynaptically साइलेंट लाइट माइक्रोस्कोपी के साथ पढ़ाई synapses Krista L. Moulder1, Xiaoping Jiang1, Amanda A. Taylor1, Ann M. Benz1, Steven Mennerick1,2,3 1Department of Psychiatry, Washington University School of Medicine, 2Department of Anatomy, Washington University School of Medicine, 3Department of Neurobiology, Washington University School of Medicine JoVE 1676 Biology
प्रतिगामी फ्लोरोसेंट लेबलिंग पहचाने गए न्यूरॉन्स से लक्षित कोशिकी एकल इकाई रिकॉर्डिंग के लिए अनुमति देता है Ariel M. Lyons-Warren1, Tsunehiko Kohashi1,2, Steven Mennerick3, Bruce A. Carlson1 1Department of Biology, Washington University in St. Louis, 2Division of Biological Science, Graduate School of Science, Nagoya University, 3Department of Psychiatry, Washington University in St. Louis JoVE 3921 Neuroscience
Presynaptically साइलेंट लाइट माइक्रोस्कोपी के साथ पढ़ाई synapses Krista L. Moulder1, Xiaoping Jiang1, Amanda A. Taylor1, Ann M. Benz1, Steven Mennerick1,2,3 1Department of Psychiatry, Washington University School of Medicine, 2Department of Anatomy, Washington University School of Medicine, 3Department of Neurobiology, Washington University School of Medicine JoVE 1676 Biology
