Subra Kugathasan Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Emory University School of Medicine and Children's Health Care of Atlanta Biography Publications Institution JoVE Articles Subra Kugathasan has not added a biography. If you are Subra Kugathasan and would like to personalize this page please email our Author Liaison for assistance. Publications Multidimensional Prognostic Risk Assessment Identifies Association Between IL12B Variation and Surgery in Crohn's Disease Inflammatory Bowel Diseases. May, 2013 | Pubmed ID: 23665963 Safety, Tolerability, and Clinical Response After Fecal Transplantation in Children and Young Adults with Ulcerative Colitis Journal of Pediatric Gastroenterology and Nutrition. Mar, 2013 | Pubmed ID: 23542823 Incidence, Clinical Characteristics, and Natural History of Pediatric IBD in Wisconsin: a Population-based Epidemiological Study Inflammatory Bowel Diseases. Mar, 2013 | Pubmed ID: 23528339 Challenges in IBD Research: Update on Progress and Prioritization of the CCFA's Research Agenda Inflammatory Bowel Diseases. Mar, 2013 | Pubmed ID: 23448796 Vertebral Osteomyelitis Due to Candida Parapsilosis in a Child with Crohn Disease While Receiving Anti-TNF Therapy Journal of Pediatric Gastroenterology and Nutrition. Apr, 2013 | Pubmed ID: 23201701 IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis Inflammatory Bowel Diseases. Jan, 2013 | Pubmed ID: 22550014 Circulating Antibodies Against Bacterial Wall Products: Are There Arguments for Early Immunosuppression? Digestive Diseases (Basel, Switzerland). 2012 | Pubmed ID: 23295693 Host-microbe Interactions Have Shaped the Genetic Architecture of Inflammatory Bowel Disease Nature. Nov, 2012 | Pubmed ID: 23128233 Markers That Differentiate Early from Late IBD Digestive Diseases (Basel, Switzerland). 2012 | Pubmed ID: 22796800 The Age of Gene Discovery in Very Early Onset Inflammatory Bowel Disease Gastroenterology. Aug, 2012 | Pubmed ID: 22727850 Commentaries on "Workshop Report: Developing a Pediatric Inflammatory Bowel Diseases Network and Data Platform in Canada": Pediatric Inflammatory Bowel Disease Networks: Raising the Bar Journal of Pediatric Gastroenterology and Nutrition. Aug, 2012 | Pubmed ID: 22659890 Comparison of Magnetic Resonance Enterography with Endoscopy, Histopathology, and Laboratory Evaluation in Pediatric Crohn Disease Journal of Pediatric Gastroenterology and Nutrition. Aug, 2012 | Pubmed ID: 22513710 Common NOD2 Risk Variants in African Americans with Crohn's Disease Are Due Exclusively to Recent Caucasian Admixture Inflammatory Bowel Diseases. Dec, 2012 | Pubmed ID: 22447396 Contribution of Higher Risk Genes and European Admixture to Crohn's Disease in African Americans Inflammatory Bowel Diseases. Dec, 2012 | Pubmed ID: 22411504 Induction and Maintenance Therapy with Infliximab for Children with Moderate to Severe Ulcerative Colitis Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Apr, 2012 | Pubmed ID: 22155755 Crohn's Disease and Genetic Hitchhiking at IBD5 Molecular Biology and Evolution. Jan, 2012 | Pubmed ID: 21816865 Medical Radiation Exposure in Children with Inflammatory Bowel Disease Estimates High Cumulative Doses Inflammatory Bowel Diseases. Nov, 2011 | Pubmed ID: 21987300 Association of Crohn's Disease, Thiopurines, and Primary Epstein-barr Virus Infection with Hemophagocytic Lymphohistiocytosis The Journal of Pediatrics. Nov, 2011 | Pubmed ID: 21722918 Rising Incidence of Inflammatory Bowel Disease in Young Children: What Does the Future Hold? Journal of Pediatric Gastroenterology and Nutrition. Aug, 2011 | Pubmed ID: 21637130 Genome-wide Association Identifies Diverse Causes of Common Variable Immunodeficiency The Journal of Allergy and Clinical Immunology. Jun, 2011 | Pubmed ID: 21497890 Improved Risk Prediction for Crohn's Disease with a Multi-locus Approach Human Molecular Genetics. Jun, 2011 | Pubmed ID: 21427131 Meta-analysis Identifies 29 Additional Ulcerative Colitis Risk Loci, Increasing the Number of Confirmed Associations to 47 Nature Genetics. Mar, 2011 | Pubmed ID: 21297633 Safety and Efficacy of Maintenance Infliximab Therapy for Moderate-to-severe Crohn's Disease in Children: REACH Open-label Extension Current Medical Research and Opinion. Mar, 2011 | Pubmed ID: 21241207 Medical Radiation Exposure in Children with Inflammatory Bowel Disease Estimates High Cumulative Doses Inflammatory Bowel Diseases. Jan, 2011 | Pubmed ID: 21234907 Real-time Tool to Display the Predicted Disease Course and Treatment Response for Children with Crohn's Disease Inflammatory Bowel Diseases. Jan, 2011 | Pubmed ID: 20812335 Genome-wide Meta-analysis Increases to 71 the Number of Confirmed Crohn's Disease Susceptibility Loci Nature Genetics. Dec, 2010 | Pubmed ID: 21102463 Association of Linear Growth Impairment in Pediatric Crohn's Disease and a Known Height Locus: a Pilot Study Annals of Human Genetics. Nov, 2010 | Pubmed ID: 20846217 Factors That Determine Risk for Surgery in Pediatric Patients with Crohn's Disease Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Sep, 2010 | Pubmed ID: 20566311 Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease and Their Relation to Disease Type and Severity Journal of Pediatric Gastroenterology and Nutrition. Aug, 2010 | Pubmed ID: 20453677 Inflammatory Bowel Disease in Children: Current Trends Journal of Gastroenterology. Jul, 2010 | Pubmed ID: 20414789 Severe Pediatric Ulcerative Colitis: a Prospective Multicenter Study of Outcomes and Predictors of Response Gastroenterology. Jun, 2010 | Pubmed ID: 20193683 Comparative Genetic Analysis of Inflammatory Bowel Disease and Type 1 Diabetes Implicates Multiple Loci with Opposite Effects Human Molecular Genetics. May, 2010 | Pubmed ID: 20176734 Pediatric Inflammatory Bowel Disease: Highlighting Pediatric Differences in IBD The Medical Clinics of North America. Jan, 2010 | Pubmed ID: 19944797 Lipopolysaccharide Exposure is Linked to Activation of the Acute Phase Response and Growth Failure in Pediatric Crohn's Disease and Murine Colitis Inflammatory Bowel Diseases. May, 2010 | Pubmed ID: 19924809 Brief Report: Development of the Inflammatory Bowel Disease Family Responsibility Questionnaire Journal of Pediatric Psychology. Mar, 2010 | Pubmed ID: 19564243 Barriers to Adherence Among Adolescents with Inflammatory Bowel Disease Inflammatory Bowel Diseases. Jan, 2010 | Pubmed ID: 19434722 Common Variants at Five New Loci Associated with Early-onset Inflammatory Bowel Disease Nature Genetics. Dec, 2009 | Pubmed ID: 19915574 Pediatric Inflammatory Bowel Disease: Highlighting Pediatric Differences in IBD Gastroenterology Clinics of North America. Dec, 2009 | Pubmed ID: 19913205 Genetic Determinants of Pediatric Inflammatory Bowel Disease: is Age of Onset Genetically Determined? Digestive Diseases (Basel, Switzerland). 2009 | Pubmed ID: 19786746 Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (RESEAT) in Pediatric Crohn's Disease The American Journal of Gastroenterology. Dec, 2009 | Pubmed ID: 19724267 Infliximab Therapy in Children with Concurrent Perianal Crohn Disease: Observations from REACH Journal of Pediatric Gastroenterology and Nutrition. Aug, 2009 | Pubmed ID: 19561542 Established Genetic Risk Factors Do Not Distinguish Early and Later Onset Crohn's Disease Inflammatory Bowel Diseases. Oct, 2009 | Pubmed ID: 19322901 Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease American Journal of Human Genetics. Mar, 2009 | Pubmed ID: 19249008 Growth Abnormalities Persist in Newly Diagnosed Children with Crohn Disease Despite Current Treatment Paradigms Journal of Pediatric Gastroenterology and Nutrition. Feb, 2009 | Pubmed ID: 19179878 Appraisal of the Pediatric Ulcerative Colitis Activity Index (PUCAI) Inflammatory Bowel Diseases. Aug, 2009 | Pubmed ID: 19161178 Long-term Outcome of Maintenance Infliximab Therapy in Children with Crohn's Disease Inflammatory Bowel Diseases. Jun, 2009 | Pubmed ID: 19107783 Age of Diagnosis Influences Serologic Responses in Children with Crohn's Disease: a Possible Clue to Etiology? Inflammatory Bowel Diseases. May, 2009 | Pubmed ID: 19107777 Course and Treatment of Perianal Disease in Children Newly Diagnosed with Crohn's Disease Inflammatory Bowel Diseases. Mar, 2009 | Pubmed ID: 19023863 Improvement in Biomarkers of Bone Formation During Infliximab Therapy in Pediatric Crohn's Disease: Results of the REACH Study Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Dec, 2008 | Pubmed ID: 19081527 Searching for New Clues in Inflammatory Bowel Disease: Tell Tales from Pediatric IBD Natural History Studies Gastroenterology. Oct, 2008 | Pubmed ID: 18786536 Loci on 20q13 and 21q22 Are Associated with Pediatric-onset Inflammatory Bowel Disease Nature Genetics. Oct, 2008 | Pubmed ID: 18758464 Increased Immune Reactivity Predicts Aggressive Complicating Crohn's Disease in Children Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Oct, 2008 | Pubmed ID: 18619921 Effect of Early Immunomodulator Use in Moderate to Severe Pediatric Crohn Disease Inflammatory Bowel Diseases. Jul, 2008 | Pubmed ID: 18306311 Fecal Calprotectin is Useful in Predicting Disease Relapse in Pediatric Inflammatory Bowel Disease Inflammatory Bowel Diseases. May, 2008 | Pubmed ID: 18240279 CARD15 and IL23R Influences Crohn's Disease Susceptibility but Not Disease Phenotype in a Brazilian Population Inflammatory Bowel Diseases. May, 2008 | Pubmed ID: 18200510 Methotrexate Following Unsuccessful Thiopurine Therapy in Pediatric Crohn's Disease The American Journal of Gastroenterology. Dec, 2007 | Pubmed ID: 18042110 Body Mass Index in Children with Newly Diagnosed Inflammatory Bowel Disease: Observations from Two Multicenter North American Inception Cohorts The Journal of Pediatrics. Nov, 2007 | Pubmed ID: 17961699 Pediatric Onset Crohn's Colitis is Characterized by Genotype-dependent Age-related Susceptibility Inflammatory Bowel Diseases. Dec, 2007 | Pubmed ID: 17763471 Progress in Basic Inflammatory Bowel Disease Research Seminars in Pediatric Surgery. Aug, 2007 | Pubmed ID: 17602969 Pediatric Inflammatory Bowel Disease: Clinical and Molecular Genetics Inflammatory Bowel Diseases. Nov, 2007 | Pubmed ID: 17600381 Laboratory Values for Children with Newly Diagnosed Inflammatory Bowel Disease Pediatrics. Jun, 2007 | Pubmed ID: 17545378 Analysis of Keratin Polypeptides 8 and 19 Variants in Inflammatory Bowel Disease Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Jul, 2007 | Pubmed ID: 17509943 Differentiating Ulcerative Colitis from Crohn Disease in Children and Young Adults: Report of a Working Group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America Journal of Pediatric Gastroenterology and Nutrition. May, 2007 | Pubmed ID: 17460505 Induction and Maintenance Infliximab Therapy for the Treatment of Moderate-to-severe Crohn's Disease in Children Gastroenterology. Mar, 2007 | Pubmed ID: 17324398 Intercenter Variation in Initial Management of Children with Crohn's Disease Inflammatory Bowel Diseases. Jul, 2007 | Pubmed ID: 17286275 Natalizumab Therapy for Moderate to Severe Crohn Disease in Adolescents Journal of Pediatric Gastroenterology and Nutrition. Feb, 2007 | Pubmed ID: 17255829 DLG5 R30Q Variant is a Female-specific Protective Factor in Pediatric Onset Crohn's Disease The American Journal of Gastroenterology. Feb, 2007 | Pubmed ID: 17156146 What Are the Risk Factors for Surgery and Their Implications for Management of Children with Crohn's Disease? Nature Clinical Practice. Gastroenterology & Hepatology. Dec, 2006 | Pubmed ID: 17130872 Functional Genomics and Its Implications for Molecular Medicine Pediatric Clinics of North America. Oct, 2006 | Pubmed ID: 17027611 Challenges in Pediatric Inflammatory Bowel Disease Inflammatory Bowel Diseases. Sep, 2006 | Pubmed ID: 16954808 Health-related Quality of Life in the First Year After a Diagnosis of Pediatric Inflammatory Bowel Disease Inflammatory Bowel Diseases. Aug, 2006 | Pubmed ID: 16917222 Inflammatory Bowel Disease--environmental Modification and Genetic Determinants Pediatric Clinics of North America. Aug, 2006 | Pubmed ID: 16873002 Corticosteroid Therapy in the Age of Infliximab: Acute and 1-year Outcomes in Newly Diagnosed Children with Crohn's Disease Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Sep, 2006 | Pubmed ID: 16861053 The Natural History of Corticosteroid Therapy for Ulcerative Colitis in Children Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Sep, 2006 | Pubmed ID: 16820327 Contribution of OCTN Variants Within the IBD5 Locus to Pediatric Onset Crohn's Disease The American Journal of Gastroenterology. Jun, 2006 | Pubmed ID: 16771961 Evidence of Transmission Ratio Distortion of DLG5 R30Q Variant in General and Implication of an Association with Crohn Disease in Men Human Genetics. Apr, 2006 | Pubmed ID: 16446977 Molecular Stratification of Crohn's Disease by Chemokine Receptors: Fractalkine Receptor Polymorphisms Define a Fibrostenosing Ileal Subgroup The American Journal of Gastroenterology. Jan, 2006 | Pubmed ID: 16405541 Evaluation of the Pediatric Crohn Disease Activity Index: a Prospective Multicenter Experience Journal of Pediatric Gastroenterology and Nutrition. Oct, 2005 | Pubmed ID: 16205508 Severe Colitis in Children Journal of Pediatric Gastroenterology and Nutrition. Oct, 2005 | Pubmed ID: 16205502 A Randomized, Double-blind Trial of Lactobacillus GG Versus Placebo in Addition to Standard Maintenance Therapy for Children with Crohn's Disease Inflammatory Bowel Diseases. Sep, 2005 | Pubmed ID: 16116318 Asymptomatic Inflammatory Bowel Disease Presenting with Mucocutaneous Findings Pediatrics. Sep, 2005 | Pubmed ID: 16099852 Comparative Phenotypic and CARD15 Mutational Analysis Among African American, Hispanic, and White Children with Crohn's Disease Inflammatory Bowel Diseases. Jul, 2005 | Pubmed ID: 15973116 CARD15 Gene Mutations and Risk for Early Surgery in Pediatric-onset Crohn's Disease Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Nov, 2004 | Pubmed ID: 15551253 Guidelines for Immunizations in Patients with Inflammatory Bowel Disease Inflammatory Bowel Diseases. Sep, 2004 | Pubmed ID: 15472534 Inflammatory Bowel Disease Adolescent Medicine Clinics. Feb, 2004 | Pubmed ID: 15272257 Pancreatitis in Children Journal of Pediatric Gastroenterology and Nutrition. Nov, 2003 | Pubmed ID: 14581803 Epidemiologic and Clinical Characteristics of Children with Newly Diagnosed Inflammatory Bowel Disease in Wisconsin: a Statewide Population-based Study The Journal of Pediatrics. Oct, 2003 | Pubmed ID: 14571234 Dermatologic Manifestations of Crohn Disease in Children: Response to Infliximab Journal of Pediatric Gastroenterology and Nutrition. Aug, 2003 | Pubmed ID: 12883301 Pancreatitis As a Presenting Manifestation of Pediatric Crohn's Disease: a Report of Three Cases Journal of Pediatric Gastroenterology and Nutrition. Jul, 2002 | Pubmed ID: 12142820 Infliximab Retreatment in Adults and Children with Crohn's Disease: Risk Factors for the Development of Delayed Severe Systemic Reaction The American Journal of Gastroenterology. Jun, 2002 | Pubmed ID: 12094858 Ureteropelvic Junction Obstruction: an Overlooked Cause of Cyclic Vomiting The American Journal of Gastroenterology. Apr, 2002 | Pubmed ID: 12003386 A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation Jon Waters1, Vishal Dhere1, Adam Benjamin1, Arvind Sekar1, Archana Kumar1, Sampath Prahalad2, David T. Okou1, Subra Kugathasan1 1Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University School of Medicine and Children's Health Care of Atlanta, 2Division of Rheumatology, Department of Pediatrics, Emory University School of Medicine and Children's Health Care of Atlanta JoVE 4241 Biology
A Practical and Novel Method to Extract Genomic DNA from Blood Collection Kits for Plasma Protein Preservation Jon Waters1, Vishal Dhere1, Adam Benjamin1, Arvind Sekar1, Archana Kumar1, Sampath Prahalad2, David T. Okou1, Subra Kugathasan1 1Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University School of Medicine and Children's Health Care of Atlanta, 2Division of Rheumatology, Department of Pediatrics, Emory University School of Medicine and Children's Health Care of Atlanta JoVE 4241 Biology
