Sunny Xia Molecular Medicine Hospital for Sick Children Biography Publications Institution JoVE Articles Sunny Xia has not added a biography. If you are Sunny Xia and would like to personalize this page please email our Author Liaison for assistance. Publications Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function Current Protocols. Jan, 2022 | Pubmed ID: 35025140 High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in IPSC-Derived Human Intestinal Organoids Cells. 12, 2021 | Pubmed ID: 34943927 Generation of Functional Ciliated Cholangiocytes from Human Pluripotent Stem Cells Nature Communications. 11, 2021 | Pubmed ID: 34764255 Perspectives on the Translation of In-vitro Studies to Precision Medicine in Cystic Fibrosis EBioMedicine. Nov, 2021 | Pubmed ID: 34740114 A New Platform for High-throughput Therapy Testing on IPSC-derived Lung Progenitor Cells from Cystic Fibrosis Patients Stem Cell Reports. 11, 2021 | Pubmed ID: 34678210 VacA Generates a Protective Intracellular Reservoir for Helicobacter Pylori That is Eliminated by Activation of the Lysosomal Calcium Channel TRPML1 Nature Microbiology. 08, 2019 | Pubmed ID: 31110360 Efficient Generation of Functional CFTR-expressing Airway Epithelial Cells from Human Pluripotent Stem Cells Nature Protocols. Mar, 2015 | Pubmed ID: 25654755 An Organoid Model to Assay the Role of CFTR in the Human Epididymis Epithelium Cell and Tissue Research. | Pubmed ID: 32377875 ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel Molecular Pharmacology. | Pubmed ID: 31427400 Conversion of Human and Mouse Fibroblasts into Lung-like Epithelial Cells Scientific Reports. | Pubmed ID: 31227724 Augmentation of Cystic Fibrosis Transmembrane Conductance Regulator Function in Human Bronchial Epithelial Cells Via SLC6A14-Dependent Amino Acid Uptake. Implications for Treatment of Cystic Fibrosis American Journal of Respiratory Cell and Molecular Biology. | Pubmed ID: 31189070 SLC6A14, an Amino Acid Transporter, Modifies the Primary CF Defect in Fluid Secretion ELife. | Pubmed ID: 30004386 Phenotypic Profiling of CFTR Modulators in Patient-derived Respiratory Epithelia NPJ Genomic Medicine. | Pubmed ID: 28649446 A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines Sunny Xia1,3, Michelle Di Paola3, Nicola L. Jones2,4,5, Christine E. Bear1,3,5 1Molecular Medicine, Hospital for Sick Children, 2Cell Biology, Hospital for Sick Children, 3Department of Physiology, University of Toronto, 4Department of Paediatrics, University of Toronto, 5Department of Biochemistry, University of Toronto JoVE 63528 Biology
A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines Sunny Xia1,3, Michelle Di Paola3, Nicola L. Jones2,4,5, Christine E. Bear1,3,5 1Molecular Medicine, Hospital for Sick Children, 2Cell Biology, Hospital for Sick Children, 3Department of Physiology, University of Toronto, 4Department of Paediatrics, University of Toronto, 5Department of Biochemistry, University of Toronto JoVE 63528 Biology
