In JoVE (1)
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Articles by Sydney C. Lindner in JoVE
Rodent Behavioral Testing to Assess Functional Deficits Caused by Microelectrode Implantation in the Rat Motor Cortex Monika Goss-Varley1,2, Andrew J. Shoffstall1,2, Keith R. Dona1,2, Justin A. McMahon1,2, Sydney C. Lindner1,2, Evon S. Ereifej1,2, Jeffrey R. Capadona1,2 1Advanced Platform Technology Center, Rehabilitation Research and Development, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, 2Department of Biomedical Engineering, Case Western Reserve University We have shown that a microelectrode implantation in the motor cortex of rats causes immediate and lasting motor deficits. The methods proposed herein outline a microelectrode implantation surgery and three rodent behavioral tasks to elucidate potential changes in the fine or gross motor function due to implantation-caused damage to the motor cortex.