Sylvie Lesage

Publications

• TCR Transgenic Mice Reveal the Impact of Type 1 Diabetes Loci on Early and Late Disease Checkpoints
  Immunology and Cell Biology. Aug, 2016  |   Pubmed ID: 27046082
• Genetic Predisposition for Beta Cell Fragility Underlies Type 1 and Type 2 Diabetes
  Nature Genetics. May, 2016  |   Pubmed ID: 26998692
• IL23R (Interleukin 23 Receptor) Variants Protective Against Inflammatory Bowel Diseases (IBD) Display Loss of Function Due to Impaired Protein Stability and Intracellular Trafficking
  The Journal of Biological Chemistry. Apr, 2016  |   Pubmed ID: 26887945
• NK Cell Proportion and Number Are Influenced by Genetic Loci on Chromosomes 8, 9, and 17
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2016  |   Pubmed ID: 26851217
• Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity
  The Journal of Biological Chemistry. Feb, 2016  |   Pubmed ID: 26742847
• Autoimmunity and Antibody Affinity Maturation Are Modulated by Genetic Variants on Mouse Chromosome 12
  Journal of Autoimmunity. Apr, 2015  |   Pubmed ID: 25623266
• Functional Characterization of CaVα2δ Mutations Associated with Sudden Cardiac Death
  The Journal of Biological Chemistry. Jan, 2015  |   Pubmed ID: 25527503
• Specific Targeting of the IL-23 Receptor, Using a Novel Small Peptide Noncompetitive Antagonist, Decreases the Inflammatory Response
  American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Nov, 2014  |   Pubmed ID: 25354400
• The Mouse Idd2 Locus is Linked to the Proportion of Immunoregulatory Double-negative T Cells, a Trait Associated with Autoimmune Diabetes Resistance
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2014  |   Pubmed ID: 25165153
• The Dichotomous Pattern of IL-12r and IL-23R Expression Elucidates the Role of IL-12 and IL-23 in Inflammation
  PloS One. 2014  |   Pubmed ID: 24586521
• A ZAP-70 Kinase Domain Variant Prevents Thymocyte-positive Selection Despite Signalling CD69 Induction
  Immunology. Apr, 2014  |   Pubmed ID: 24266404
• Revisiting the Prominent Anti-Tumoral Potential of Pre-mNK Cells
  Frontiers in Immunology. 2013  |   Pubmed ID: 24376447
• Nearby Construction Impedes the Progression to Overt Autoimmune Diabetes in NOD Mice
  Journal of Diabetes Research. 2013  |   Pubmed ID: 23691516
• The Idd13 Congenic Interval Defines the Number of Merocytic Dendritic Cells, A novel Trait Associated with Autoimmune Diabetes Susceptibility
  Journal of Autoimmunity. Jun, 2013  |   Pubmed ID: 23623717
• Immunoregulatory CD4(-)CD8(-) T Cells As a Potential Therapeutic Tool for Transplantation, Autoimmunity, and Cancer
  Frontiers in Immunology. 2013  |   Pubmed ID: 23355840
• Unusual Selection and Peripheral Homeostasis for Immunoregulatory CD4(-)  CD8(-) T Cells
  Immunology. May, 2013  |   Pubmed ID: 23293940
• A Comprehensive Review of the Phenotype and Function of Antigen-specific Immunoregulatory Double Negative T Cells
  Journal of Autoimmunity. Feb, 2013  |   Pubmed ID: 22910322
• The Size of the Plasmacytoid Dendritic Cell Compartment is a Multigenic Trait Dominated by a Locus on Mouse Chromosome 7
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2012  |   Pubmed ID: 22547694
• Redefining Interferon-producing Killer Dendritic Cells As a Novel Intermediate in NK-cell Differentiation
  Blood. May, 2012  |   Pubmed ID: 22353997
• Molecular and Genetic Parameters Defining T-cell Clonal Selection
  Immunology and Cell Biology. Jan, 2011  |   Pubmed ID: 20956988
• Interleukin-10 Limits the Expansion of Immunoregulatory CD4-CD8- T Cells in Autoimmune-prone Non-obese Diabetic Mice
  Immunology and Cell Biology. Nov-Dec, 2010  |   Pubmed ID: 20603635
• Implication of the CD47 Pathway in Autoimmune Diabetes
  Journal of Autoimmunity. Aug, 2010  |   Pubmed ID: 20138735
• Cutting Edge: Genetic Characterization of IFN-producing Killer Dendritic Cells
  Journal of Immunology (Baltimore, Md. : 1950). May, 2009  |   Pubmed ID: 19380763
• Absence of CD47 in Vivo Influences Thymic Dendritic Cell Subset Proportions but Not Negative Selection of Thymocytes
  International Immunology. Feb, 2009  |   Pubmed ID: 19147837
• Cutting Edge: CD47 Controls the in Vivo Proliferation and Homeostasis of Peripheral CD4+ CD25+ Foxp3+ Regulatory T Cells That Express CD103
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008  |   Pubmed ID: 18832672
• Expression of the Self-marker CD47 on Dendritic Cells Governs Their Trafficking to Secondary Lymphoid Organs
  The EMBO Journal. Nov, 2006  |   Pubmed ID: 17093498
• Genetic Lesions in T-cell Tolerance and Thresholds for Autoimmunity
  Immunological Reviews. Apr, 2005  |   Pubmed ID: 15790352
• Generalized Resistance to Thymic Deletion in the NOD Mouse; a Polygenic Trait Characterized by Defective Induction of Bim
  Immunity. Dec, 2004  |   Pubmed ID: 15589170
• Gene Dosage--limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity
  The Journal of Experimental Medicine. Oct, 2004  |   Pubmed ID: 15492124
• A Cell Death Pathway Induced by Antibody-mediated Cross-linking of CD45 on Lymphocytes
  Critical Reviews in Immunology. 2003  |   Pubmed ID: 15030310
• Identifying the MAGUK Protein Carma-1 As a Central Regulator of Humoral Immune Responses and Atopy by Genome-wide Mouse Mutagenesis
  Immunity. Jun, 2003  |   Pubmed ID: 12818157
• T Cell Tolerance to a Neo-self Antigen Expressed by Thymic Epithelial Cells: the Soluble Form is More Effective Than the Membrane-bound Form
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2003  |   Pubmed ID: 12682222
• Aire Regulates Negative Selection of Organ-specific T Cells
  Nature Immunology. Apr, 2003  |   Pubmed ID: 12612579
• Failure to Censor Forbidden Clones of CD4 T Cells in Autoimmune Diabetes
  The Journal of Experimental Medicine. Nov, 2002  |   Pubmed ID: 12417628
• Spinal Cord Compression of Dual Etiology, Multiple Myeloma and Spinal Tuberculosis
  Leukemia & Lymphoma. Feb, 2002  |   Pubmed ID: 11999581