Szymon M. Kielbasa Department of Medical Statistics and Bioinformatics Leiden University Medical Center Biography Publications Institution JoVE Articles Szymon M. Kielbasa has not added a biography. If you are Szymon M. Kielbasa and would like to personalize this page please email our Author Liaison for assistance. Publications NKG2A is a Late Immune Checkpoint on CD8 T Cells and Marks Repeated Stimulation and Cell Division International Journal of Cancer. 02, 2022 | Pubmed ID: 34716584 The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy The Journal of Clinical Endocrinology and Metabolism. 01, 2022 | Pubmed ID: 34546342 Blood RNA Signature RISK4LEP Predicts Leprosy Years Before Clinical Onset EBioMedicine. Jun, 2021 | Pubmed ID: 34090257 Hippocampal Glucocorticoid Target Genes Associated with Enhancement of Memory Consolidation The European Journal of Neuroscience. Apr, 2021 | Pubmed ID: 33840130 CACTUS: Integrating Clonal Architecture with Genomic Clustering and Transcriptome Profiling of Single Tumor Cells Genome Medicine. 03, 2021 | Pubmed ID: 33761980 Statistical Method for Modeling Sequencing Data from Different Technologies in Longitudinal Studies with Application to Huntington Disease Biometrical Journal. Biometrische Zeitschrift. 04, 2021 | Pubmed ID: 33350510 Comprehensive Diagnostics of Acute Myeloid Leukemia by Whole Transcriptome RNA Sequencing Leukemia. 01, 2021 | Pubmed ID: 32127641 Exacerbated Inflammatory Signaling Underlies Aberrant Response to BMP9 in Pulmonary Arterial Hypertension Lung Endothelial Cells Angiogenesis. 11, 2020 | Pubmed ID: 32813135 Templated Insertions at VD and DJ Junctions Create Unique B-cell Receptors in the Healthy B-cell Repertoire European Journal of Immunology. 12, 2020 | Pubmed ID: 32762049 Optimized Whole Genome Association Scanning for Discovery of HLA Class I-Restricted Minor Histocompatibility Antigens Frontiers in Immunology. 2020 | Pubmed ID: 32362897 Eleven Grand Challenges in Single-cell Data Science Genome Biology. 02, 2020 | Pubmed ID: 32033589 Peripheral IgE Repertoires of Healthy Donors Carry Moderate Mutation Loads and Do Not Overlap With Other Isotypes Frontiers in Immunology. 2019 | Pubmed ID: 31333671 RNA-Seq in 296 Phased Trios Provides a High-resolution Map of Genomic Imprinting BMC Biology. 06, 2019 | Pubmed ID: 31234833 Acquired N-Linked Glycosylation Motifs in B-Cell Receptors of Primary Cutaneous B-Cell Lymphoma and the Normal B-Cell Repertoire The Journal of Investigative Dermatology. 10, 2019 | Pubmed ID: 31042459 Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting IScience. Feb, 2019 | Pubmed ID: 30739015 Skewed X-inactivation is Common in the General Female Population European Journal of Human Genetics : EJHG. 03, 2019 | Pubmed ID: 30552425 RNA Sequencing Data Integration Reveals an MiRNA Interactome of Osteoarthritis Cartilage Annals of the Rheumatic Diseases. 02, 2019 | Pubmed ID: 30504444 Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice Endocrinology. 12, 2018 | Pubmed ID: 30321321 Human Bone Marrow-Resident Natural Killer Cells Have a Unique Transcriptional Profile and Resemble Resident Memory CD8 T Cells Frontiers in Immunology. 2018 | Pubmed ID: 30186282 Impact of Congenital Cytomegalovirus Infection on Transcriptomes from Archived Dried Blood Spots in Relation to Long-term Clinical Outcome PloS One. 2018 | Pubmed ID: 30024899 Transcriptional Profiling and Biomarker Identification Reveal Tissue Specific Effects of Expanded Ataxin-3 in a Spinocerebellar Ataxia Type 3 Mouse Model Molecular Neurodegeneration. 06, 2018 | Pubmed ID: 29929540 Brain Transcriptomic Analysis of Hereditary Cerebral Hemorrhage With Amyloidosis-Dutch Type Frontiers in Aging Neuroscience. 2018 | Pubmed ID: 29706885 The Distinct Transcriptomes of Slow and Fast Adult Muscles Are Delineated by Noncoding RNAs FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2018 | Pubmed ID: 29141996 RNA-seq Analysis of Lgr6 Stem Cells and Identification of an Lgr6 Isoform Experimental Dermatology. 10, 2018 | Pubmed ID: 28987003 Disease Variants Alter Transcription Factor Levels and Methylation of Their Binding Sites Nature Genetics. 01, 2017 | Pubmed ID: 27918535 Identification of Context-dependent Expression Quantitative Trait Loci in Whole Blood Nature Genetics. 01, 2017 | Pubmed ID: 27918533 New Function of the Myostatin/activin Type I Receptor (ALK4) As a Mediator of Muscle Atrophy and Muscle Regeneration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2017 | Pubmed ID: 27733450 Quaking Promotes Monocyte Differentiation into Pro-atherogenic Macrophages by Controlling Pre-mRNA Splicing and Gene Expression Nature Communications. Mar, 2016 | Pubmed ID: 27029405 Integrated Whole Genome and Transcriptome Analysis Identified a Therapeutic Minor Histocompatibility Antigen in a Splice Variant of ITGB2 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2016 | Pubmed ID: 26964570 Molecular Signatures of Age-associated Chronic Degeneration of Shoulder Muscles Oncotarget. Feb, 2016 | Pubmed ID: 26885755 Whole-transcriptome Analysis of Flow-sorted Cervical Cancer Samples Reveals That B Cell Expressed TCL1A is Correlated with Improved Survival Oncotarget. Nov, 2015 | Pubmed ID: 26299617 Two Plasmodium 6-Cys Family-related Proteins Have Distinct and Critical Roles in Liver-stage Development FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2014 | Pubmed ID: 24509910 Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing Yang Ge1,2, Lieke van Roon1, H. Sophia Chen1,2, Ruben Methorst1, Martin Paton2, Marco C. DeRuiter1, Szymon M. Kielbasa3, Monique R. M. Jongbloed1,2 1Department of Anatomy & Embryology, Leiden University Medical Center, 2Department of Cardiology, Leiden University Medical Center, 3Department of Medical Statistics and Bioinformatics, Leiden University Medical Center JoVE 63397 Medicine
Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing Yang Ge1,2, Lieke van Roon1, H. Sophia Chen1,2, Ruben Methorst1, Martin Paton2, Marco C. DeRuiter1, Szymon M. Kielbasa3, Monique R. M. Jongbloed1,2 1Department of Anatomy & Embryology, Leiden University Medical Center, 2Department of Cardiology, Leiden University Medical Center, 3Department of Medical Statistics and Bioinformatics, Leiden University Medical Center JoVE 63397 Medicine
