Thilo Kähne Institute of Experimental Internal Medicine Medical School, Otto von Guericke University Magdeburg Biography Publications Institution JoVE Articles Thilo Kähne has not added a biography. If you are Thilo Kähne and would like to personalize this page please email our Author Liaison for assistance. Publications Immunoproteasome Induction is Suppressed in Hepatitis C Virus-infected Cells in a Protein Kinase R-dependent Manner Experimental & Molecular Medicine. Nov, 2016 | Pubmed ID: 27833096 14-3-3 Proteins Regulate K2P 5.1 Surface Expression on T Lymphocytes Traffic (Copenhagen, Denmark). Oct, 2016 | Pubmed ID: 27743426 Proteome Rearrangements After Auditory Learning: High-resolution Profiling of Synapse-enriched Protein Fractions from Mouse Brain Journal of Neurochemistry. Jul, 2016 | Pubmed ID: 27062398 New Insights Into the Mechanism of COP9 Signalosome-Cullin-RING Ubiquitin-Ligase Pathway Deregulation in Urological Cancers International Review of Cell and Molecular Biology. 2016 | Pubmed ID: 26944622 Synapsin is Required to "boost" Memory Strength for Highly Salient Events Learning & Memory (Cold Spring Harbor, N.Y.). Jan, 2016 | Pubmed ID: 26670182 Role of Calprotectin As a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells Mediators of Inflammation. 2015 | Pubmed ID: 26663990 Synapsin Determines Memory Strength After Punishment- and Relief-learning The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2015 | Pubmed ID: 25972175 Differential Effects of Dopamine Signalling on Long-term Memory Formation and Consolidation in Rodent Brain Proteome Science. 2015 | Pubmed ID: 25852303 DNA-dependent Protein Kinase (DNA-PK) Permits Vascular Smooth Muscle Cell Proliferation Through Phosphorylation of the Orphan Nuclear Receptor NOR1 Cardiovascular Research. Jun, 2015 | Pubmed ID: 25852083 Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus Cell. Feb, 2013 | Pubmed ID: 23452857 Synaptic Proteome Changes in Mouse Brain Regions Upon Auditory Discrimination Learning Proteomics. Aug, 2012 | Pubmed ID: 22696468 The Major Soyabean Allergen P34 Resists Proteolysis in Vitro and is Transported Through Intestinal Epithelial Cells by a Caveolae-mediated Mechanism The British Journal of Nutrition. Nov, 2012 | Pubmed ID: 22244500 Methodologic Issues in the Measurement of Interleukin-16 in Clinical Blood Samples Using Immunoassays Cytokine. Apr, 2012 | Pubmed ID: 22239948 Gender and Age-dependent Differences in the Bradykinin-degradation Within the Pericardial Fluid of Patients with Coronary Artery Disease International Journal of Cardiology. Jan, 2011 | Pubmed ID: 19592120 Interleukin 1 Beta (IL1B) Gene Polymorphisms Are Not Associated with Gastric Carcinogenesis in Germany Anticancer Research. Feb, 2010 | Pubmed ID: 20332462 Cathepsin L Inactivates Human Trypsinogen, Whereas Cathepsin L-deletion Reduces the Severity of Pancreatitis in Mice Gastroenterology. Feb, 2010 | Pubmed ID: 19900452 Non-T Cell Activation Linker Regulates ERK Activation in Helicobacter Pylori-infected Epithelial Cells Cellular Signalling. Mar, 2010 | Pubmed ID: 19879355 Congenital Lack of NNOS Impairs Long-term Social Recognition Memory and Alters the Olfactory Bulb Proteome Neurobiology of Learning and Memory. Nov, 2009 | Pubmed ID: 19531381 Cathepsin K Generates Enkephalin from Beta-endorphin: a New Mechanism with Possible Relevance for Schizophrenia Neurochemistry International. Jun, 2009 | Pubmed ID: 19428782 The GABAergic System in the Retina of Neonate and Adult Octodon Degus, Studied by Immunohistochemistry and Electroretinography The Journal of Comparative Neurology. Jun, 2009 | Pubmed ID: 19350652 Host-pathogen Systems Biology: Logical Modelling of Hepatocyte Growth Factor and Helicobacter Pylori Induced C-Met Signal Transduction BMC Systems Biology. Jan, 2008 | Pubmed ID: 18194572 Subcellular Localization of Grb2 by the Adaptor Protein Dok-3 Restricts the Intensity of Ca2+ Signaling in B Cells The EMBO Journal. Feb, 2007 | Pubmed ID: 17290227 Inhibitors of Dipeptidyl Peptidase IV and Aminopeptidase N Target Major Pathogenetic Steps in Acne Initiation The Journal of Investigative Dermatology. May, 2007 | Pubmed ID: 16778789 Attractin, a Dipeptidyl Peptidase IV/CD26-like Enzyme, is Expressed on Human Peripheral Blood Monocytes and Potentially Influences Monocyte Function Journal of Leukocyte Biology. Sep, 2006 | Pubmed ID: 16835316 Possible Role of DP IV Inhibitors in Acne Therapy Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 16700519 Expression of Dipeptidyl Peptidase IV-like Enzymes in Human Peripheral Blood Mononuclear Cells Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 16700511 A Degradation-sensitive Anionic Trypsinogen (PRSS2) Variant Protects Against Chronic Pancreatitis Nature Genetics. Jun, 2006 | Pubmed ID: 16699518 The Association Between the Interleukin-1 Polymorphisms and Gastric Cancer Risk Depends on the Family History of Gastric Carcinoma in the Study Population The American Journal of Gastroenterology. Feb, 2006 | Pubmed ID: 16454826 ALys Amyloidosis Caused by Compound Heterozygosity in Exon 2 (Thr70Asn) and Exon 4 (Trp112Arg) of the Lysozyme Gene Human Mutation. Jan, 2006 | Pubmed ID: 16329101 Expression of Gp130 in Tumors and Inflammatory Disorders of the Skin: Formal Proof of Its Identity As CD146 (MUC18, Mel-CAM) The Journal of Investigative Dermatology. Aug, 2005 | Pubmed ID: 16098047 Consequences of COP9 Signalosome and 26S Proteasome Interaction The FEBS Journal. Aug, 2005 | Pubmed ID: 16045761 RNA-binding Proteins Heterogeneous Nuclear Ribonucleoprotein A1, E1, and K Are Involved in Post-transcriptional Control of Collagen I and III Synthesis Circulation Research. Nov, 2004 | Pubmed ID: 15514164 Proteome Analysis of Gastric Cancer Metastasis by Two-dimensional Gel Electrophoresis and Matrix Assisted Laser Desorption/ionization-mass Spectrometry for Identification of Metastasis-related Proteins Journal of Proteome Research. Sep-Oct, 2004 | Pubmed ID: 15473690 Radioresistance-related Proteins in Rectal Cancer Proteomics. Aug, 2004 | Pubmed ID: 15274120 Clinical Proteomics in Lung Diseases Pathology, Research and Practice. 2004 | Pubmed ID: 15237923 Proteomics in Myocardial Diseases Pathology, Research and Practice. 2004 | Pubmed ID: 15237922 Expression and Functional Proteomics Studies in Colorectal Cancer Pathology, Research and Practice. 2004 | Pubmed ID: 15237920 Involvement of Napsin A in the C- and N-terminal Processing of Surfactant Protein B in Type-II Pneumocytes of the Human Lung The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 13129928 Different Modes of Dipeptidyl Peptidase IV (CD26) Inhibition by Oligopeptides Derived from the N-terminus of HIV-1 Tat Indicate at Least Two Inhibitor Binding Sites European Journal of Biochemistry. May, 2003 | Pubmed ID: 12752434 Transcriptional Regulation of Cytosol and Membrane Alanyl-aminopeptidase in Human T Cell Subsets Biological Chemistry. Apr, 2003 | Pubmed ID: 12751795 Dipeptidyl Peptidase IV Inhibitors with the N-terminal MXP Sequence: Structure-activity-relationships Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 12675237 Synergistic Action of DPIV and APN in the Regulation of T Cell Function Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 12675232 Different Inhibition Mechanisms of Dipeptidyl Peptidase IV by Tryptophan Containing Peptides and Amides Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 12675225 Molecular Chimeras and Mutational Analysis in the Prolyl Oligopeptidase Gene Family Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 12675222 Posttranscriptional Control of Renin Synthesis: Identification of Proteins Interacting with Renin MRNA 3'-untranslated Region Circulation Research. Mar, 2003 | Pubmed ID: 12600897 Structural Requirements for Catalysis, Expression, and Dimerization in the CD26/DPIV Gene Family Biochemistry. Jan, 2003 | Pubmed ID: 12534281 The Role of Dipeptidyl Peptidase IV (DP IV) Enzymatic Activity in T Cell Activation and Autoimmunity Biological Chemistry. Jul-Aug, 2002 | Pubmed ID: 12437097 Transcellular Proteolysis Demonstrated by Novel Cell Surface-associated Substrates of Dipeptidyl Peptidase IV (CD26) The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12095981 Inhibition of Human Leukocyte Function, Alanyl Aminopeptidase (APN, CD13) and Dipeptidylpeptidase IV (DP IV, CD26) Enzymatic Activities by Aqueous Extracts of Cistus Incanus L. Ssp. Incanus Journal of Ethnopharmacology. Feb, 2002 | Pubmed ID: 11801385 High Resolution Quantitative Synaptic Proteome Profiling of Mouse Brain Regions After Auditory Discrimination Learning Angela Kolodziej1, Karl-Heinz Smalla1, Sandra Richter2, Alexander Engler1, Rainer Pielot1,3, Daniela C. Dieterich3, Wolfgang Tischmeyer1, Michael Naumann2, Thilo Kähne2 1Leibniz Institute for Neurobiology (LIN), 2Institute of Experimental Internal Medicine, Medical School, Otto von Guericke University Magdeburg, 3Institute of Pharmacology and Toxicology, Medical School, Otto von Guericke University JoVE 54992 Neuroscience
High Resolution Quantitative Synaptic Proteome Profiling of Mouse Brain Regions After Auditory Discrimination Learning Angela Kolodziej1, Karl-Heinz Smalla1, Sandra Richter2, Alexander Engler1, Rainer Pielot1,3, Daniela C. Dieterich3, Wolfgang Tischmeyer1, Michael Naumann2, Thilo Kähne2 1Leibniz Institute for Neurobiology (LIN), 2Institute of Experimental Internal Medicine, Medical School, Otto von Guericke University Magdeburg, 3Institute of Pharmacology and Toxicology, Medical School, Otto von Guericke University JoVE 54992 Neuroscience
