Thomas C. Rich Department of Pharmacology University of South Alabama Biography Publications Institution JoVE Articles Thomas C. Rich has not added a biography. If you are Thomas C. Rich and would like to personalize this page please email our Author Liaison for assistance. Publications Milestones in the Development and Implementation of FRET-based Sensors of Intracellular Signals: A Biological Perspective of the History of FRET Cellular Signalling. Nov, 2020 | Pubmed ID: 32898611 Development of an Endothelial Cell-restricted Transgenic Reporter Rat: a Resource for Physiological Studies of Vascular Biology American Journal of Physiology. Heart and Circulatory Physiology. 08, 2020 | Pubmed ID: 32589443 Label-free Spectroscopic Tissue Characterization Using Fluorescence Excitation-scanning Spectral Imaging Journal of Biophotonics. 02, 2020 | Pubmed ID: 31566889 Applications and Assessment of an Excitation-scanning Hyperspectral Imaging System Proceedings of SPIE--the International Society for Optical Engineering. Jan-Feb, 2018 | Pubmed ID: 31762531 Identifying Molecular Contributors to Autofluorescence of Neoplastic and Normal Colon Sections Using Excitation-scanning Hyperspectral Imaging Journal of Biomedical Optics. 12, 2018 | Pubmed ID: 30592190 Spectral Imaging of FRET-based Sensors Reveals Sustained CAMP Gradients in Three Spatial Dimensions Cytometry. Part A : the Journal of the International Society for Analytical Cytology. 10, 2018 | Pubmed ID: 30176184 Human ASIC1a Mediates Stronger Acid-induced Responses As Compared with Mouse ASIC1a FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2018 | Pubmed ID: 29447005 A Theoretical-experimental Methodology for Assessing the Sensitivity of Biomedical Spectral Imaging Platforms, Assays, and Analysis Methods Journal of Biophotonics. Jan, 2018 | Pubmed ID: 28485093 Hyperspectral Imaging Fluorescence Excitation Scanning for Colon Cancer Detection Journal of Biomedical Optics. 10, 2016 | Pubmed ID: 27792808 Overcoming Limitations of FRET Measurements Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Apr, 2016 | Pubmed ID: 27101317 Estimating the Magnitude of Near-membrane PDE4 Activity in Living Cells American Journal of Physiology. Cell Physiology. Sep, 2015 | Pubmed ID: 26201952 Channel-based Reporters for CAMP Detection Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25783878 Automated Image Analysis of FRET Signals for Subcellular CAMP Quantification Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25783877 Sodium Entry Through Endothelial Store-operated Calcium Entry Channels: Regulation by Orai1 American Journal of Physiology. Cell Physiology. Feb, 2015 | Pubmed ID: 25428882 FRET: Signals Hidden Within the Noise Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2014 | Pubmed ID: 25241962 β-Agonist-mediated Relaxation of Airway Smooth Muscle is Protein Kinase A-dependent The Journal of Biological Chemistry. Aug, 2014 | Pubmed ID: 24973219 Excitation-scanning Hyperspectral Imaging Microscope Journal of Biomedical Optics. Apr, 2014 | Pubmed ID: 24727909 Can We Decipher the Information Content Contained Within Cyclic Nucleotide Signals? The Journal of General Physiology. Jan, 2014 | Pubmed ID: 24378904 Assessing FRET Using Spectral Techniques Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Oct, 2013 | Pubmed ID: 23929684 An Approach for Characterizing and Comparing Hyperspectral Microscopy Systems Sensors (Basel, Switzerland). Jul, 2013 | Pubmed ID: 23877125 Hyperspectral Imaging of FRET-based CGMP Probes Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23709027 Feedback Regulation of Cone Cyclic Nucleotide Channels by Phosphoinositides. Focus on "CNGA3 Achromatopsia-associated Mutation Potentiates the Phosphoinositide Sensitivity of Cone Photoreceptor CNG Channels by Altering Intersubunit Interactions" American Journal of Physiology. Cell Physiology. Jul, 2013 | Pubmed ID: 23677796 Calcineurin Regulates Homologous Desensitization of Natriuretic Peptide Receptor-A and Inhibits ANP-induced Testosterone Production in MA-10 Cells PloS One. 2012 | Pubmed ID: 22876290 A-kinase Anchoring Proteins Regulate Compartmentalized CAMP Signaling in Airway Smooth Muscle FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2012 | Pubmed ID: 22649031 Assessment of Cellular Mechanisms Contributing to CAMP Compartmentalization in Pulmonary Microvascular Endothelial Cells American Journal of Physiology. Cell Physiology. Mar, 2012 | Pubmed ID: 22116306 Hyperspectral Imaging Microscopy for Identification and Quantitative Analysis of Fluorescently-labeled Cells in Highly Autofluorescent Tissue Journal of Biophotonics. Jan, 2012 | Pubmed ID: 21987373 All Preconditioning-related G Protein-coupled Receptors Can Be Demonstrated in the Rabbit Cardiomyocyte Journal of Cardiovascular Pharmacology and Therapeutics. Jun, 2012 | Pubmed ID: 21828281 Inactivation of Multidrug Resistance Proteins Disrupts Both Cellular Extrusion and Intracellular Degradation of CAMP Molecular Pharmacology. Aug, 2011 | Pubmed ID: 21551375 A2B Adenosine Receptors Inhibit Superoxide Production from Mitochondrial Complex I in Rabbit Cardiomyocytes Via a Mechanism Sensitive to Pertussis Toxin British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21366548 PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21288894 Quantitative Modeling of GRK-mediated Beta2AR Regulation PLoS Computational Biology. Jan, 2010 | Pubmed ID: 20098494 Receptor Reserve Reflects Differential Intrinsic Efficacy Associated with Opioid Diastereomers Pharmacology, Biochemistry, and Behavior. May, 2009 | Pubmed ID: 19463265 Roles of GRK and PDE4 Activities in the Regulation of Beta2 Adrenergic Signaling The Journal of General Physiology. Apr, 2008 | Pubmed ID: 18347080 Cellular Mechanisms Underlying Prostaglandin-induced Transient CAMP Signals Near the Plasma Membrane of HEK-293 Cells American Journal of Physiology. Cell Physiology. Jan, 2007 | Pubmed ID: 16899551 Medición de distribuciones de cAMP tridimensionales en células vivas utilizando imágenes y análisis FRET hiperespectrales de 4 dimensiones (x, y, z y λ) Naga S. Annamdevula1,2, Rachel Sweat3, Hayden Gunn1, John R. Griswold3, Andrea L. Britain1,2, Thomas C. Rich1,2, Silas J. Leavesley1,2,3 1Department of Pharmacology, University of South Alabama, 2Center for Lung Biology, University of South Alabama, 3Department of Chemical and Biomolecular Engineering, University of South Alabama JoVE 61720 Biology
Medición de distribuciones de cAMP tridimensionales en células vivas utilizando imágenes y análisis FRET hiperespectrales de 4 dimensiones (x, y, z y λ) Naga S. Annamdevula1,2, Rachel Sweat3, Hayden Gunn1, John R. Griswold3, Andrea L. Britain1,2, Thomas C. Rich1,2, Silas J. Leavesley1,2,3 1Department of Pharmacology, University of South Alabama, 2Center for Lung Biology, University of South Alabama, 3Department of Chemical and Biomolecular Engineering, University of South Alabama JoVE 61720 Biology
