Thomas Douglas Biogeochemical Sciences Branch, Cold Regions Research and Engineering Laboratory US Army Engineer Research & Development Center, Fairbanks, AK Biography Publications Institution JoVE Articles Thomas Douglas has not added a biography. If you are Thomas Douglas and would like to personalize this page please email our Author Liaison for assistance. Publications Ascorbic Acid Attenuates Hyperoxia-Compromised Host Defense Against Pulmonary Bacterial Infection American Journal of Respiratory Cell and Molecular Biology. Apr, 2016 | Pubmed ID: 27120084 Duties to Rescue: Individual, Professional and Institutional Journal of Medical Ethics. Apr, 2016 | Pubmed ID: 27004742 Why is Cognitive Enhancement Deemed Unacceptable? The Role of Fairness, Deservingness, and Hollow Achievements Frontiers in Psychology. 2016 | Pubmed ID: 26925027 Methadone for Prisoners Lancet (London, England). Jan, 2016 | Pubmed ID: 26842294 Genome Editing Technologies and Human Germline Genetic Modification: The Hinxton Group Consensus Statement The American Journal of Bioethics : AJOB. Dec, 2015 | Pubmed ID: 26632362 CRISPR: A Path Through the Thicket Nature. Nov, 2015 | Pubmed ID: 26560284 Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications Cancer Research. Dec, 2015 | Pubmed ID: 26542213 Substituted Judgment, Procreative Beneficence, and the Ashley Treatment Journal of Medical Ethics. Sep, 2015 | Pubmed ID: 26304130 Signaling and Stress: The Redox Landscape in NOS2 Biology Free Radical Biology & Medicine. Oct, 2015 | Pubmed ID: 26117324 The Moral Imperative to Continue Gene Editing Research on Human Embryos Protein & Cell. Jul, 2015 | Pubmed ID: 26113289 Sex Offenders Seeking Treatment for Sexual Dysfunction--Ethics, Medicine, and the Law The Journal of Sexual Medicine. Jul, 2015 | Pubmed ID: 26060942 Breathing New Life into Nitric Oxide Signaling: A Brief Overview of the Interplay Between Oxygen and Nitric Oxide Redox Biology. Aug, 2015 | Pubmed ID: 26056766 Proximity of Arteries to the Anterior Ulna with Changing Flexion Orthopedics. Apr, 2015 | Pubmed ID: 25901616 The Harms of Enhancement and the Conclusive Reasons View Cambridge Quarterly of Healthcare Ethics : CQ : the International Journal of Healthcare Ethics Committees. Jan, 2015 | Pubmed ID: 25473855 The Compromise of Macrophage Functions by Hyperoxia is Attenuated by Ethacrynic Acid Via Inhibition of NF-κB-mediated Release of High-mobility Group Box-1 American Journal of Respiratory Cell and Molecular Biology. Feb, 2015 | Pubmed ID: 24992505 Stocking the Genetic Supermarket: Reproductive Genetic Technologies and Collective Action Problems Bioethics. May, 2015 | Pubmed ID: 24720568 Are You Morally Modified?: The Moral Effects of Widely Used Pharmaceuticals Philosophy, Psychiatry, & Psychology : PPP. Jun, 2014 | Pubmed ID: 25892904 The Dual-use Problem, Scientific Isolationism and the Division of Moral Labour Monash Bioethics Review. Mar-Jun, 2014 | Pubmed ID: 25507664 The Dual-use Problem, Scientific Isolationism and the Division of Moral Labour Monash Bioethics Review. Mar-Jun, 2014 | Pubmed ID: 25434066 Stem Cell-derived Gametes, Iterated in Vitro Reproduction, and Genetic Parenthood Journal of Medical Ethics. Nov, 2014 | Pubmed ID: 25332370 The Regulation of Cognitive Enhancement Devices: Extending the Medical Model Journal of Law and the Biosciences. Mar, 2014 | Pubmed ID: 25243073 Insights into the Diverse Effects of Nitric Oxide on Tumor Biology Vitamins and Hormones. 2014 | Pubmed ID: 25189391 Criminal Rehabilitation Through Medical Intervention: Moral Liability and the Right to Bodily Integrity The Journal of Ethics. Jun, 2014 | Pubmed ID: 25009441 The Relationship Between Effort and Moral Worth: Three Amendments to Sorensen's Model Ethical Theory and Moral Practice : an International Forum. Apr, 2014 | Pubmed ID: 24991189 Enhancement and Civic Virtue Social Theory and Practice. Jul, 2014 | Pubmed ID: 24882886 Moral Bioenhancement, Freedom and Reasoning Journal of Medical Ethics. Jun, 2014 | Pubmed ID: 24840918 Enhancing Moral Conformity and Enhancing Moral Worth Neuroethics. 2014 | Pubmed ID: 24600486 Inhibition of Extracellular HMGB1 Attenuates Hyperoxia-induced Inflammatory Acute Lung Injury Redox Biology. 2014 | Pubmed ID: 24563849 Convective Forcing of Mercury and Ozone in the Arctic Boundary Layer Induced by Leads in Sea Ice Nature. Feb, 2014 | Pubmed ID: 24429521 Regulation of Devices for Cognitive Enhancement Lancet (London, England). Sep, 2013 | Pubmed ID: 24034296 Oxygen Dependence of Nitric Oxide-mediated Signaling Redox Biology. 2013 | Pubmed ID: 24024154 Procreative Altruism: Beyond Individualism in Reproductive Selection The Journal of Medicine and Philosophy. Aug, 2013 | Pubmed ID: 23856478 Coercion, Incarceration, and Chemical Castration: an Argument from Autonomy Journal of Bioethical Inquiry. Oct, 2013 | Pubmed ID: 23813324 Is the Creation of Artificial Life Morally Significant? Studies in History and Philosophy of Biological and Biomedical Sciences. Dec, 2013 | Pubmed ID: 23810562 Human Enhancement and Supra-personal Moral Status Philosophical Studies. Feb, 2013 | Pubmed ID: 23576821 Nitric Oxide Modifies Global Histone Methylation by Inhibiting Jumonji C Domain-containing Demethylases The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23546878 Biosecurity and the Division of Cognitive Labour Journal of Medical Ethics. Apr, 2013 | Pubmed ID: 23508647 A Concise Argument: on the Wrongness of Killing Journal of Medical Ethics. Jan, 2013 | Pubmed ID: 23247758 The Harms of Status Enhancement Could Be Compensated or Outweighed: a Response to Agar Journal of Medical Ethics. Feb, 2013 | Pubmed ID: 23047835 Moral Enhancement Via Direct Emotion Modulation: a Reply to John Harris Bioethics. Mar, 2013 | Pubmed ID: 22092503 Procreative Beneficence and in Vitro Gametogenesis Monash Bioethics Review. Sep, 2012 | Pubmed ID: 23409535 Engineering and Ethical Perspectives in Synthetic Biology. Rigorous, Robust and Predictable Designs, Public Engagement and a Modern Ethical Framework Are Vital to the Continued Success of Synthetic Biology EMBO Reports. Jul, 2012 | Pubmed ID: 22699939 S-nitrosation: Current Concepts and New Developments Antioxidants & Redox Signaling. Oct, 2012 | Pubmed ID: 22530975 Is NICE Ageist? Highlights from This Issue Journal of Medical Ethics. May, 2012 | Pubmed ID: 22518054 Is S-nitrosocysteine a True Surrogate for Nitric Oxide? Antioxidants & Redox Signaling. Oct, 2012 | Pubmed ID: 22304688 Self-serving Bias and the Structure of Moral Status Journal of Medical Ethics. Mar, 2012 | Pubmed ID: 22174328 Nitric Oxide Suppresses Tumor Cell Migration Through N-Myc Downstream-regulated Gene-1 (NDRG1) Expression: Role of Chelatable Iron The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 21976667 Dinitrosyliron Complexes Are the Most Abundant Nitric Oxide-derived Cellular Adduct: Biological Parameters of Assembly and Disappearance Free Radical Biology & Medicine. Oct, 2011 | Pubmed ID: 21787861 Dissolution and Sorption of Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and 2,4,6-trinitrotoluene (TNT) Residues from Detonated Mineral Surfaces Chemosphere. Aug, 2011 | Pubmed ID: 21601233 Desorption of Nitramine and Nitroaromatic Explosive Residues from Soils Detonated Under Controlled Conditions Environmental Toxicology and Chemistry / SETAC. Feb, 2011 | Pubmed ID: 21038362 Intertemporal Disagreement and Empirical Slippery Slope Arguments Utilitas. Jun, 2010 | Pubmed ID: 21516214 SHOULD INSTITUTIONS PRIORITIZE RECTIFICATION OVER AID? The Philosophical Quarterly. Oct, 2010 | Pubmed ID: 21423857 Synthetic Biology and the Ethics of Knowledge Journal of Medical Ethics. Nov, 2010 | Pubmed ID: 20935316 Australian Attitudes to Early and Late Abortion The Medical Journal of Australia. Jul, 2010 | Pubmed ID: 20618106 Resisting Sparrow's Sexy Reductio: Selection Principles and the Social Good The American Journal of Bioethics : AJOB. Jul, 2010 | Pubmed ID: 20582820 Nitric Oxide and Cancer Therapy: the Emperor Has NO Clothes Current Pharmaceutical Design. 2010 | Pubmed ID: 20236067 Tomitella Biformata Gen. Nov., Sp. Nov., a New Member of the Suborder Corynebacterineae Isolated from a Permafrost Ice Wedge International Journal of Systematic and Evolutionary Microbiology. Dec, 2010 | Pubmed ID: 20081023 Investigating the Fate of Nitroaromatic (TNT) and Nitramine (RDX and HMX) Explosives in Fractured and Pristine Soils Journal of Environmental Quality. Nov-Dec, 2009 | Pubmed ID: 19875785 Absence of Significant Dissent Should Be Sufficient for Deceased Donor Organ Procurement in New Zealand Australian and New Zealand Journal of Public Health. Oct, 2009 | Pubmed ID: 19811481 Monomeric and Oligomeric Amine-borane Sigma-complexes of Rhodium. Intermediates in the Catalytic Dehydrogenation of Amine-boranes Journal of the American Chemical Society. Oct, 2009 | Pubmed ID: 19785431 Comparing the Chemical Biology of NO and HNO Archives of Pharmacal Research. Aug, 2009 | Pubmed ID: 19727606 Destroying Unwanted Embryos in Research. Talking Point on Morality and Human Embryo Research EMBO Reports. Apr, 2009 | Pubmed ID: 19337299 A Time Series Investigation of the Stability of Nitramine and Nitroaromatic Explosives in Surface Water Samples at Ambient Temperature Chemosphere. Jun, 2009 | Pubmed ID: 19329139 Glaciibacter Superstes Gen. Nov., Sp. Nov., a Novel Member of the Family Microbacteriaceae Isolated from a Permafrost Ice Wedge International Journal of Systematic and Evolutionary Microbiology. Mar, 2009 | Pubmed ID: 19244426 Medical Injury Compensation: Beyond 'no-fault' Medical Law Review. 2009 | Pubmed ID: 19095721 Moral Enhancement Journal of Applied Philosophy. Aug, 2008 | Pubmed ID: 19132138 Consequentialism and the Death Penalty The American Journal of Bioethics : AJOB. Oct, 2008 | Pubmed ID: 19003713 Amine-borane Sigma-complexes of Rhodium. Relevance to the Catalytic Dehydrogenation of Amine-boranes Journal of the American Chemical Society. Nov, 2008 | Pubmed ID: 18844358 Molecular Mechanisms for Discrete Nitric Oxide Levels in Cancer Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Sep, 2008 | Pubmed ID: 18472020 Influence of Snow and Ice Crystal Formation and Accumulation on Mercury Deposition to the Arctic Environmental Science & Technology. Mar, 2008 | Pubmed ID: 18441801 The Chemical Biology of Nitric Oxide: Implications in Cellular Signaling Free Radical Biology & Medicine. Jul, 2008 | Pubmed ID: 18439435 Reversible Addition of Water to the High-hydride-content Cluster [Rh6(PiPr3)6H12][BArF4]2. Synthesis and Structure of [Rh6PiPr3)6H11(OH)][BArF4]2 Inorganic Chemistry. Feb, 2008 | Pubmed ID: 18181618 Intramolecular Alkyl Phosphine Dehydrogenation in Cationic Rhodium Complexes of Tris(cyclopentylphosphine) Chemistry (Weinheim an Der Bergstrasse, Germany). 2008 | Pubmed ID: 17992682 Enhancement in Sport, and Enhancement Outside Sport Studies in Ethics, Law, and Technology. Dec, 2007 | Pubmed ID: 19750128 Nitric Oxide Regulates Matrix Metalloproteinase-9 Activity by Guanylyl-cyclase-dependent and -independent Pathways Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17942699 Phylogenetic Analysis of Bacteria Preserved in a Permafrost Ice Wedge for 25,000 Years Applied and Environmental Microbiology. Apr, 2007 | Pubmed ID: 17293514 Inflammation and IGF-I Activate the Akt Pathway in Breast Cancer International Journal of Cancer. Feb, 2007 | Pubmed ID: 17096325 Asbestos Redirects Nitric Oxide Signaling Through Rapid Catalytic Conversion to Nitrite Cancer Research. Dec, 2006 | Pubmed ID: 17178853 The Role of Halogenated Carborane Monoanions in Olefin Hydrogenation Catalysed by Cationic Iridium Phosphine Complexes Dalton Transactions (Cambridge, England : 2003). Dec, 2006 | Pubmed ID: 17117219 Peroxynitrite and Myocardial Contractility: in Vivo Versus in Vitro Effects Free Radical Biology & Medicine. Nov, 2006 | Pubmed ID: 17045928 The Activation of Metabolites of Nitric Oxide Synthase by Metals is Both Redox and Oxygen Dependent: a New Feature of Nitrogen Oxide Signaling Antioxidants & Redox Signaling. Jul-Aug, 2006 | Pubmed ID: 16910783 The Biphasic Nature of Nitric Oxide Responses in Tumor Biology Antioxidants & Redox Signaling. Jul-Aug, 2006 | Pubmed ID: 16910780 Phosphine-olefin Ligands: a Facile Dehydrogenative Route to Catalytically Active Rhodium Complexes Chemical Communications (Cambridge, England). Aug, 2006 | Pubmed ID: 16896477 Superoxide Fluxes Limit Nitric Oxide-induced Signaling The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16829532 Discriminating Formation of HNO from Other Reactive Nitrogen Oxide Species Free Radical Biology & Medicine. Mar, 2006 | Pubmed ID: 16540401 Guanylyl Cyclase-dependent Chemotaxis of Endothelial Cells in Response to Nitric Oxide Gradients Free Radical Biology & Medicine. Mar, 2006 | Pubmed ID: 16540398 Nitric Oxide Regulates Angiogenesis Through a Functional Switch Involving Thrombospondin-1 Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005 | Pubmed ID: 16141331 Pili Trianguli Et Canaliculi is a Defect of Inner Root Sheath Keratinization: Ultrastructural Observations of Anomalous Tonofilament Organization in a Case The American Journal of Dermatopathology. Jun, 2005 | Pubmed ID: 15900128 Mechanism of Aerobic Decomposition of Angeli's Salt (sodium Trioxodinitrate) at Physiological PH Journal of the American Chemical Society. Jan, 2005 | Pubmed ID: 15643898 The Chemical Dynamics of NO and Reactive Nitrogen Oxides: a Practical Guide Current Molecular Medicine. Nov, 2004 | Pubmed ID: 15579020 Hypoxic Inducible Factor 1alpha, Extracellular Signal-regulated Kinase, and P53 Are Regulated by Distinct Threshold Concentrations of Nitric Oxide Proceedings of the National Academy of Sciences of the United States of America. Jun, 2004 | Pubmed ID: 15178764 The Chemistry of Nitrosative Stress Induced by Nitric Oxide and Reactive Nitrogen Oxide Species. Putting Perspective on Stressful Biological Situations Biological Chemistry. Jan, 2004 | Pubmed ID: 14977040 Viral-associated Trichodysplasia in Patients Who Are Immunocompromised Journal of the American Academy of Dermatology. Feb, 2004 | Pubmed ID: 14726896 Heme Proteins and Nitric Oxide (NO): the Neglected, Eloquent Chemistry in NO Redox Signaling and Regulation Antioxidants & Redox Signaling. Jun, 2003 | Pubmed ID: 12880485 A Biochemical Rationale for the Discrete Behavior of Nitroxyl and Nitric Oxide in the Cardiovascular System Proceedings of the National Academy of Sciences of the United States of America. Aug, 2003 | Pubmed ID: 12865500 Orthogonal Properties of the Redox Siblings Nitroxyl and Nitric Oxide in the Cardiovascular System: a Novel Redox Paradigm American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2003 | Pubmed ID: 12855429 Comparison of the Reactivity of Nitric Oxide and Nitroxyl with Heme Proteins. A Chemical Discussion of the Differential Biological Effects of These Redox Related Products of NOS Journal of Inorganic Biochemistry. Jan, 2003 | Pubmed ID: 12538052 Guide for the Use of Nitric Oxide (NO) Donors As Probes of the Chemistry of NO and Related Redox Species in Biological Systems Methods in Enzymology. 2002 | Pubmed ID: 12481562 Protein Nitration is Mediated by Heme and Free Metals Through Fenton-type Chemistry: an Alternative to the NO/O2- Reaction Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12226478 Ingress and Reactive Chemistry of Nitroxyl-derived Species Within Human Cells Free Radical Biology & Medicine. Sep, 2002 | Pubmed ID: 12208370 Focusing of Nitric Oxide Mediated Nitrosation and Oxidative Nitrosylation As a Consequence of Reaction with Superoxide Proceedings of the National Academy of Sciences of the United States of America. Aug, 2002 | Pubmed ID: 12177414 A Chemical Perspective on the Interplay Between NO, Reactive Oxygen Species, and Reactive Nitrogen Oxide Species Annals of the New York Academy of Sciences. May, 2002 | Pubmed ID: 12076975 Further Evidence for Distinct Reactive Intermediates from Nitroxyl and Peroxynitrite: Effects of Buffer Composition on the Chemistry of Angeli's Salt and Synthetic Peroxynitrite Archives of Biochemistry and Biophysics. May, 2002 | Pubmed ID: 12054463 Direct Real-time Evaluation of Nitration with Green Fluorescent Protein in Solution and Within Human Cells Reveals the Impact of Nitrogen Dioxide Vs. Peroxynitrite Mechanisms Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11904413 Verwijdering van exogene materialen uit het buitenste gedeelte van Frozen Cores tot de Oude Biologische Gemeenschappen koesterde Inside Onderzoek Robyn A. Barbato1, Natàlia Garcia-Reyero2, Karen Foley1, Robert Jones1, Zoe Courville3, Thomas Douglas4, Edward Perkins2, Charles M. Reynolds4 1Biogeochemical Sciences Branch, Cold Regions Research and Engineering Laboratory, US Army Engineer Research & Development Center, Hanover, NH, 2Environmental Processes Branch, Environmental Laboratory, US Army Engineer Research & Development Center, Vicksburg, MS, 3Terrestrial and Cryospheric Scienes Branch, Cold Regions Research and Engineering Laboratory, US Army Engineer Research & Development Center, Hanover, NH, 4Biogeochemical Sciences Branch, Cold Regions Research and Engineering Laboratory, US Army Engineer Research & Development Center, Fairbanks, AK JoVE 54091 Biology
Verwijdering van exogene materialen uit het buitenste gedeelte van Frozen Cores tot de Oude Biologische Gemeenschappen koesterde Inside Onderzoek Robyn A. Barbato1, Natàlia Garcia-Reyero2, Karen Foley1, Robert Jones1, Zoe Courville3, Thomas Douglas4, Edward Perkins2, Charles M. Reynolds4 1Biogeochemical Sciences Branch, Cold Regions Research and Engineering Laboratory, US Army Engineer Research & Development Center, Hanover, NH, 2Environmental Processes Branch, Environmental Laboratory, US Army Engineer Research & Development Center, Vicksburg, MS, 3Terrestrial and Cryospheric Scienes Branch, Cold Regions Research and Engineering Laboratory, US Army Engineer Research & Development Center, Hanover, NH, 4Biogeochemical Sciences Branch, Cold Regions Research and Engineering Laboratory, US Army Engineer Research & Development Center, Fairbanks, AK JoVE 54091 Biology
