Thomas Ebensen Department of Vaccinology and Applied Microbiology Helmholtz Centre for Infection Research Biography Publications Institution JoVE Articles Thomas Ebensen has not added a biography. If you are Thomas Ebensen and would like to personalize this page please email our Author Liaison for assistance. Publications Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Frontiers in Immunology. 2020 | Pubmed ID: 32153562 Mucosal CD8+ T Cell Responses Induced by an MCMV Based Vaccine Vector Confer Protection Against Influenza Challenge PLoS Pathogens. 09, 2019 | Pubmed ID: 31525249 Neutral Lipopolyplexes for In Vivo Delivery of Conventional and Replicative RNA Vaccine Molecular Therapy. Nucleic Acids. Sep, 2019 | Pubmed ID: 31446119 Invariant NKT Cell-Mediated Modulation of ILC1s As a Tool for Mucosal Immune Intervention Frontiers in Immunology. 2019 | Pubmed ID: 31440243 The STING Activator C-di-AMP Exerts Superior Adjuvant Properties Than the Formulation Poly(I:C)/CpG After Subcutaneous Vaccination with Soluble Protein Antigen or DEC-205-mediated Antigen Targeting to Dendritic Cells Vaccine. 08, 2019 | Pubmed ID: 31320219 Novel Colloidal Associations of Soyasaponins and Lipid Components (DPPC, Cholesterol) As Potential Adjuvants for Vaccines Vaccine. 08, 2019 | Pubmed ID: 31320217 The Combination Vaccine Adjuvant System Alum/c-di-AMP Results in Quantitative and Qualitative Enhanced Immune Responses Post Immunization Frontiers in Cellular and Infection Microbiology. 2019 | Pubmed ID: 30838180 Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids Molecular Therapy. Nucleic Acids. Sep, 2018 | Pubmed ID: 30195751 Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression Frontiers in Immunology. 2018 | Pubmed ID: 29623077 Dual Dye In-vivo Imaging of Differentially Charged PLGA Carriers Reveals Antigen-depot Effect, Leading to Improved Immune Responses in Preclinical Models European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. May, 2018 | Pubmed ID: 29408551 Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection Against Influenza H5N1 in Mice Frontiers in Immunology. 2017 | Pubmed ID: 29033942 Self-replicating RNA Vaccine Functionality Modulated by Fine-tuning of Polyplex Delivery Vehicle Structure Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2017 | Pubmed ID: 28935594 Bivalent Mucosal Peptide Vaccines Administered Using the LCP Carrier System Stimulate Protective Immune Responses Against Streptococcus Pyogenes Infection Nanomedicine : Nanotechnology, Biology, and Medicine. Nov, 2017 | Pubmed ID: 28887213 Type I IFN and Not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway EBioMedicine. Aug, 2017 | Pubmed ID: 28754303 Targeted Antigen Delivery to Dendritic Cells Elicits Robust Antiviral T Cell-mediated Immunity in the Liver Scientific Reports. Mar, 2017 | Pubmed ID: 28266658 Immunization with Tc52 or Its Amino Terminal Domain Adjuvanted with C-di-AMP Induces Th17+Th1 Specific Immune Responses and Confers Protection Against Trypanosoma Cruzi PLoS Neglected Tropical Diseases. Feb, 2017 | Pubmed ID: 28234897 Self-Replicating RNA Vaccine Delivery to Dendritic Cells Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 27987142 New Horizons in the Development of Novel Needle-Free Immunization Strategies to Increase Vaccination Efficacy Current Topics in Microbiology and Immunology. 2016 | Pubmed ID: 27370343 Modeling Influenza Virus Infection: A Roadmap for Influenza Research Viruses. Oct, 2015 | Pubmed ID: 26473911 Inverse Micellar Sugar Glass (IMSG) Nanoparticles for Transfollicular Vaccination Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2015 | Pubmed ID: 25795506 Efficient Nanoparticle-mediated Needle-free Transcutaneous Vaccination Via Hair Follicles Requires Adjuvantation Nanomedicine : Nanotechnology, Biology, and Medicine. Jan, 2015 | Pubmed ID: 25200611 Pegylated Bisacycloxypropylcysteine, a Diacylated Lipopeptide Ligand of TLR6, Plays a Host-protective Role Against Experimental Leishmania Major Infection Journal of Immunology (Baltimore, Md. : 1950). Oct, 2014 | Pubmed ID: 25194056 Intranasal Delivery of Influenza RNP Adjuvanted with C-di-AMP Induces Strong Humoral and Cellular Immune Responses and Provides Protection Against Virus Challenge PloS One. 2014 | Pubmed ID: 25140692 A New Adjuvanted Nanoparticle-based H1N1 Influenza Vaccine Induced Antigen-specific Local Mucosal and Systemic Immune Responses After Administration into the Lung Vaccine. Apr, 2014 | Pubmed ID: 24731807 Purification of Hepatitis B Surface Antigen Virus-like Particles from Recombinant Pichia Pastoris and in Vivo Analysis of Their Immunogenic Properties Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Dec, 2013 | Pubmed ID: 24141044 Vaccine Adjuvants: Key Tools for Innovative Vaccine Design Current Topics in Medicinal Chemistry. 2013 | Pubmed ID: 24066891 Development and Characterization of Attenuated Metabolic Mutants of Bordetella Bronchiseptica for Applications in Vaccinology Environmental Microbiology. Jan, 2013 | Pubmed ID: 22676396 Bis-(3',5')-cyclic Dimeric Adenosine Monophosphate: Strong Th1/Th2/Th17 Promoting Mucosal Adjuvant Vaccine. Jul, 2011 | Pubmed ID: 21619907 The Member of the Cyclic Di-nucleotide Family Bis-(3', 5')-cyclic Dimeric Inosine Monophosphate Exerts Potent Activity As Mucosal Adjuvant Vaccine. Mar, 2010 | Pubmed ID: 20060510 Immune Modulators with Defined Molecular Targets: Cornerstone to Optimize Rational Vaccine Design Advances in Experimental Medicine and Biology. 2009 | Pubmed ID: 20047042 The Toll-like Receptor 2/6 Ligand MALP-2 Reduces the Viability of Mycobacterium Tuberculosis in Murine Macrophages The Open Microbiology Journal. Apr, 2009 | Pubmed ID: 19471610 A Prime-boost Vaccination Protocol Optimizes Immune Responses Against the Nucleocapsid Protein of the SARS Coronavirus Vaccine. Dec, 2008 | Pubmed ID: 18805454 Immune Modulators with Defined Molecular Targets: Cornerstone to Optimize Rational Vaccine Design Human Vaccines. Jan-Feb, 2008 | Pubmed ID: 18376145 Oral Vaccination with Salmonella Enterica As a Cruzipain-DNA Delivery System Confers Protective Immunity Against Trypanosoma Cruzi Infection and Immunity. Jan, 2008 | Pubmed ID: 17967857 A Pegylated Derivative of Alpha-galactosylceramide Exhibits Improved Biological Properties Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17675464 The Bacterial Second Messenger CdiGMP Exhibits Promising Activity As a Mucosal Adjuvant Clinical and Vaccine Immunology : CVI. Aug, 2007 | Pubmed ID: 17567766 The Bacterial Second Messenger Cyclic DiGMP Exhibits Potent Adjuvant Properties Vaccine. Feb, 2007 | Pubmed ID: 17187906 Intranasal Vaccination with Recombinant Outer Membrane Protein CD and Adamantylamide Dipeptide As the Mucosal Adjuvant Enhances Pulmonary Clearance of Moraxella Catarrhalis in an Experimental Murine Model Infection and Immunity. Apr, 2007 | Pubmed ID: 17101651 P. aeruginosa Co-cultura 3D infetta di cellule epiteliali bronchiali e macrofagi all'interfaccia aria-liquido per la valutazione preclinica degli anti-infettivi Carlos Victor Montefusco-Pereira*1,2, Justus C. Horstmann*1,2, Thomas Ebensen3, Christoph Beisswenger4, Robert Bals4, Carlos A. Guzmán3, Nicole Schneider-Daum1, Cristiane de Souza Carvalho-Wodarz1, Claus-Michael Lehr1,2 1Department of Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), 2Department of Pharmacy, Saarland University, 3Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 4Department of Internal Medicine V - Pulmonology, Allergology, Respiratory Intensive Care Medicine, Saarland University Hospital JoVE 61069 Immunology and Infection Rapida In Vivo valutazione della funzionalità di generazione i linfociti T citotossici di adiuvante per lo sviluppo di vaccini Darío Lirussi1, Thomas Ebensen1, Kai Schulze1, Elena Reinhard1, Stephanie Trittel1, Peggy Riese1, Blair Prochnow1, Carlos A. Guzmán1 1Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research JoVE 57401 Medicine
P. aeruginosa Co-cultura 3D infetta di cellule epiteliali bronchiali e macrofagi all'interfaccia aria-liquido per la valutazione preclinica degli anti-infettivi Carlos Victor Montefusco-Pereira*1,2, Justus C. Horstmann*1,2, Thomas Ebensen3, Christoph Beisswenger4, Robert Bals4, Carlos A. Guzmán3, Nicole Schneider-Daum1, Cristiane de Souza Carvalho-Wodarz1, Claus-Michael Lehr1,2 1Department of Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), 2Department of Pharmacy, Saarland University, 3Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, 4Department of Internal Medicine V - Pulmonology, Allergology, Respiratory Intensive Care Medicine, Saarland University Hospital JoVE 61069 Immunology and Infection
Rapida In Vivo valutazione della funzionalità di generazione i linfociti T citotossici di adiuvante per lo sviluppo di vaccini Darío Lirussi1, Thomas Ebensen1, Kai Schulze1, Elena Reinhard1, Stephanie Trittel1, Peggy Riese1, Blair Prochnow1, Carlos A. Guzmán1 1Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research JoVE 57401 Medicine
