Thomas Eschenhagen Institute of Experimental Pharmacology and Toxicology University Medical Center Hamburg-Eppendorf Biography Publications Institution JoVE Articles Thomas Eschenhagen has not added a biography. If you are Thomas Eschenhagen and would like to personalize this page please email our Author Liaison for assistance. Publications Toward Standardization of Echocardiography for the Evaluation of Left Ventricular Function in Adult Rodents: a Position Paper of the ESC Working Group on Myocardial Function Cardiovascular Research. May, 2020 | Pubmed ID: 32365197 Aging-regulated Anti-apoptotic Long Non-coding RNA Sarrah Augments Recovery from Acute Myocardial Infarction Nature Communications. Apr, 2020 | Pubmed ID: 32341350 An Epidemiological Study Exploring a Possible Impact of Treatment with ACE Inhibitors or Angiotensin Receptor Blockers on ACE2 Plasma Concentrations Journal of Molecular and Cellular Cardiology. Apr, 2020 | Pubmed ID: 32268149 Regulation of I and Force by PDEs in Human-induced Pluripotent Stem Cell-derived Cardiomyocytes British Journal of Pharmacology. Feb, 2020 | Pubmed ID: 32092149 Case Report On: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes-An Artifact by Big Conductance Calcium Activated Potassium Current (I) Cells. Jan, 2020 | Pubmed ID: 31968557 Force and Calcium Transients Analysis in Human Engineered Heart Tissues Reveals Positive Force-Frequency Relation at Physiological Frequency Stem Cell Reports. Feb, 2020 | Pubmed ID: 31956082 Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive? Annual Review of Pharmacology and Toxicology. 01, 2020 | Pubmed ID: 31506008 Human Pluripotent Stem Cell-derived Cardiomyocytes for Studying Energy Metabolism Biochimica Et Biophysica Acta. Molecular Cell Research. Mar, 2020 | Pubmed ID: 30954570 Phosphomimetic Cardiac Myosin-binding Protein C Partially Rescues a Cardiomyopathy Phenotype in Murine Engineered Heart Tissue Scientific Reports. Dec, 2019 | Pubmed ID: 31796859 Disease Modeling of a Mutation in α-actinin 2 Guides Clinical Therapy in Hypertrophic Cardiomyopathy EMBO Molecular Medicine. 12, 2019 | Pubmed ID: 31680489 A Magnetics-based Approach for Fine-tuning Afterload in Engineered Heart Tissues ACS Biomaterials Science & Engineering. Jul, 2019 | Pubmed ID: 31637285 Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis Molecular Therapy. Nucleic Acids. Dec, 2019 | Pubmed ID: 31634682 Chronic Intermittent Tachypacing by an Optogenetic Approach Induces Arrhythmia Vulnerability in Human Engineered Heart Tissue Cardiovascular Research. Oct, 2019 | Pubmed ID: 31598634 Simultaneous Measurement of Excitation-contraction Coupling Parameters Identifies Mechanisms Underlying Contractile Responses of HiPSC-derived Cardiomyocytes Nature Communications. 09, 2019 | Pubmed ID: 31541103 Blockade of MiR-140-3p Prevents Functional Deterioration in Afterload-enhanced Engineered Heart Tissue Scientific Reports. 08, 2019 | Pubmed ID: 31391475 Author Correction: Differentiation of Cardiomyocytes and Generation of Human Engineered Heart Tissue Nature Protocols. Sep, 2019 | Pubmed ID: 31384055 Human IPS Cell-derived Engineered Heart Tissue Does Not Affect Ventricular Arrhythmias in a Guinea Pig Cryo-injury Model Scientific Reports. 07, 2019 | Pubmed ID: 31285568 Analysis of Fibrosis in Control or Pressure Overloaded Rat Hearts After Mechanical Unloading by Heterotopic Heart Transplantation Scientific Reports. 04, 2019 | Pubmed ID: 30952943 Dissecting HiPSC-CM Pacemaker Function in a Cardiac Organoid Model Biomaterials. Jun, 2019 | Pubmed ID: 30933775 Heart Repair With Myocytes Circulation Research. 03, 2019 | Pubmed ID: 30870126 Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors ChemMedChem. 04, 2019 | Pubmed ID: 30768867 ESC Working Group on Cellular Biology of the Heart: Position Paper for Cardiovascular Research: Tissue Engineering Strategies Combined with Cell Therapies for Cardiac Repair in Ischaemic Heart Disease and Heart Failure Cardiovascular Research. 03, 2019 | Pubmed ID: 30657875 Mechanistic Role of the CREB-regulated Transcription Coactivator 1 in Cardiac Hypertrophy Journal of Molecular and Cellular Cardiology. Feb, 2019 | Pubmed ID: 30521840 Piezo-bending Actuators for Isometric or Auxotonic Contraction Analysis of Engineered Heart Tissue Journal of Tissue Engineering and Regenerative Medicine. 01, 2019 | Pubmed ID: 30334614 Treatments Targeting Inotropy European Heart Journal. Nov, 2019 | Pubmed ID: 30295807 Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium Stem Cell Reports. Dec, 2018 | Pubmed ID: 30416051 Normalization of Force to Muscle Cross-sectional Area: A Helpful Attempt to Reduce Data Scattering in Contractility Studies? Acta Physiologica (Oxford, England). 12, 2018 | Pubmed ID: 30338659 Cardiomyopathy Phenotypes in Human-induced Pluripotent Stem Cell-derived Cardiomyocytes-a Systematic Review Pflugers Archiv : European Journal of Physiology. Oct, 2018 | Pubmed ID: 30324321 Satellite Cells Delivered in Their Niche Efficiently Generate Functional Myotubes in Three-dimensional Cell Culture PloS One. 2018 | Pubmed ID: 30222770 Rat Atrial Engineered Heart Tissue: a New in Vitro Model to Study Atrial Biology Basic Research in Cardiology. 09, 2018 | Pubmed ID: 30178427 From Basic Science to High Performance Medicine European Heart Journal. Aug, 2018 | Pubmed ID: 30165623 Exaggerated Cardiotoxicity of Sunitinib in Stressed 3-Dimensional Heart Muscles JACC. Basic to Translational Science. Apr, 2018 | Pubmed ID: 30062213 Clonal Dynamics Studied in Cultured Induced Pluripotent Stem Cells Reveal Major Growth Imbalances Within a Few Weeks Stem Cell Research & Therapy. 06, 2018 | Pubmed ID: 29914569 No Effect of Thymosin Beta-4 on the Expression of the Transcription Factor Islet-1 in the Adult Murine Heart Pharmacology Research & Perspectives. 06, 2018 | Pubmed ID: 29864245 Pharmacological Inhibition of DNA Methylation Attenuates Pressure Overload-induced Cardiac Hypertrophy in Rats Journal of Molecular and Cellular Cardiology. Jul, 2018 | Pubmed ID: 29792884 CRISPR/Cas9 Editing in Human Pluripotent Stem Cell-cardiomyocytes Highlights Arrhythmias, Hypocontractility, and Energy Depletion As Potential Therapeutic Targets for Hypertrophic Cardiomyopathy European Heart Journal. 11, 2018 | Pubmed ID: 29741611 Three-Dimensional Human IPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering Cell Reports. Apr, 2018 | Pubmed ID: 29669293 A New Concept of Fibroblast Dynamics in Post-myocardial Infarction Remodeling The Journal of Clinical Investigation. 05, 2018 | Pubmed ID: 29664015 [Cardiology 2018 : From Basic Science to High Efficiency Medicine] Herz. Mar, 2018 | Pubmed ID: 29516153 Contractile Work Contributes to Maturation of Energy Metabolism in HiPSC-Derived Cardiomyocytes Stem Cell Reports. 03, 2018 | Pubmed ID: 29503093 Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of HiPSC-Derived Cardiomyocytes Stem Cell Reports. 03, 2018 | Pubmed ID: 29429959 MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo Circulation Research. Feb, 2018 | Pubmed ID: 29282212 Cardiovascular Research in Germany Circulation Research. 08, 2017 | Pubmed ID: 28819038 Prominent Differences in Left Ventricular Performance and Myocardial Properties Between Right Ventricular and Left Ventricular-based Pacing Modes in Rats Scientific Reports. 07, 2017 | Pubmed ID: 28725029 Human IPSC-derived Cardiomyocytes Cultured in 3D Engineered Heart Tissue Show Physiological Upstroke Velocity and Sodium Current Density Scientific Reports. Jul, 2017 | Pubmed ID: 28710467 Cardiomyocyte Regeneration: A Consensus Statement Circulation. 08, 2017 | Pubmed ID: 28684531 Evaluation of MYBPC3 Trans-Splicing and Gene Replacement As Therapeutic Options in Human IPSC-Derived Cardiomyocytes Molecular Therapy. Nucleic Acids. Jun, 2017 | Pubmed ID: 28624223 Differentiation of Cardiomyocytes and Generation of Human Engineered Heart Tissue Nature Protocols. Jun, 2017 | Pubmed ID: 28492526 Blinded Contractility Analysis in HiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae Toxicological Sciences : an Official Journal of the Society of Toxicology. 07, 2017 | Pubmed ID: 28453742 Engineering Cardiac Muscle Tissue: A Maturating Field of Research Circulation Research. Apr, 2017 | Pubmed ID: 28450366 Thymosin β4 Improves Differentiation and Vascularization of EHTs Stem Cells International. 2017 | Pubmed ID: 28191018 Diltiazem Prevents Stress-induced Contractile Deficits in Cardiomyocytes, but Does Not Reverse the Cardiomyopathy Phenotype in Mybpc3-knock-in Mice The Journal of Physiology. Jan, 2017 | Pubmed ID: 28090637 Epigallocatechin-3-Gallate Accelerates Relaxation and Ca(2+) Transient Decay and Desensitizes Myofilaments in Healthy and Mybpc3-Targeted Knock-in Cardiomyopathic Mice Frontiers in Physiology. 2016 | Pubmed ID: 27994558 Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation PloS One. 2016 | Pubmed ID: 27875570 Cardiac Repair in Guinea Pigs with Human Engineered Heart Tissue from Induced Pluripotent Stem Cells Science Translational Medicine. Nov, 2016 | Pubmed ID: 27807283 Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions Frontiers in Pharmacology. 2016 | Pubmed ID: 27672365 Is Stimulation of Cardiomyocyte Renewal a Facette of Reversible Catecholamine Toxicity? Circulation Research. Sep, 2016 | Pubmed ID: 27635079 Exogenous Nitric Oxide Protects Human Embryonic Stem Cell-Derived Cardiomyocytes Against Ischemia/Reperfusion Injury Oxidative Medicine and Cellular Longevity. 2016 | Pubmed ID: 27403231 Block of Na(+)/Ca(2+) Exchanger by SEA0400 in Human Right Atrial Preparations from Patients in Sinus Rhythm and in Atrial Fibrillation European Journal of Pharmacology. Oct, 2016 | Pubmed ID: 27373849 Outcomes of Patients in Long-Term Opioid Maintenance Treatment Substance Use & Misuse. Sep, 2016 | Pubmed ID: 27355105 Human Engineered Heart Tissue: Analysis of Contractile Force Stem Cell Reports. Jul, 2016 | Pubmed ID: 27211213 Comparison of the Effects of a Truncating and a Missense MYBPC3 Mutation on Contractile Parameters of Engineered Heart Tissue Journal of Molecular and Cellular Cardiology. Aug, 2016 | Pubmed ID: 27108529 Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: Cell-based Therapies for Myocardial Repair and Regeneration in Ischemic Heart Disease and Heart Failure European Heart Journal. Apr, 2016 | Pubmed ID: 27055812 Ataxin-10 is Part of a Cachexokine Cocktail Triggering Cardiac Metabolic Dysfunction in Cancer Cachexia Molecular Metabolism. Feb, 2016 | Pubmed ID: 26909315 Myocardial Tissue Engineering for Cardiac Repair The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2016 | Pubmed ID: 26856673 A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation PloS One. 2016 | Pubmed ID: 26841021 Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue PloS One. 2016 | Pubmed ID: 26840448 S-glutathiolation Impairs Phosphoregulation and Function of Cardiac Myosin-binding Protein C in Human Heart Failure FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2016 | Pubmed ID: 26839380 Spontaneous Formation of Extensive Vessel-Like Structures in Murine Engineered Heart Tissue Tissue Engineering. Part A. Feb, 2016 | Pubmed ID: 26763667 DNA Methylation in an Engineered Heart Tissue Model of Cardiac Hypertrophy: Common Signatures and Effects of DNA Methylation Inhibitors Basic Research in Cardiology. Jan, 2016 | Pubmed ID: 26680771 Knock-out of Nexilin in Mice Leads to Dilated Cardiomyopathy and Endomyocardial Fibroelastosis Basic Research in Cardiology. Jan, 2016 | Pubmed ID: 26659360 Heart Regeneration Biochimica Et Biophysica Acta. Jul, 2016 | Pubmed ID: 26597703 General Practitioners' Adherence to Chronic Heart Failure Guidelines Regarding Medication: the GP-HF Study Clinical Research in Cardiology : Official Journal of the German Cardiac Society. May, 2016 | Pubmed ID: 26552905 Ranolazine Antagonizes Catecholamine-induced Dysfunction in Isolated Cardiomyocytes, but Lacks Long-term Therapeutic Effects in Vivo in a Mouse Model of Hypertrophic Cardiomyopathy Cardiovascular Research. Jan, 2016 | Pubmed ID: 26531128 Pharmacokinetics of the Experimental Non-Nucleosidic DNA Methyl Transferase Inhibitor N-Phthalyl-L-Tryptophan (RG 108) in Rats Basic & Clinical Pharmacology & Toxicology. May, 2016 | Pubmed ID: 26525153 Human Engineered Heart Tissue As a Model System for Drug Testing Advanced Drug Delivery Reviews. Jan, 2016 | Pubmed ID: 26026976 I-1-deficiency Negatively Impacts Survival in a Cardiomyopathy Mouse Model International Journal of Cardiology. Heart & Vasculature. Sep, 2015 | Pubmed ID: 28785686 β 1 Adrenoceptor Antagonistic Effects of the Supposedly Selective β 2 Adrenoceptor Antagonist ICI 118,551 on the Positive Inotropic Effect of Adrenaline in Murine Hearts Pharmacology Research & Perspectives. Oct, 2015 | Pubmed ID: 26516580 Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization Journal of the American College of Cardiology. Nov, 2015 | Pubmed ID: 26516004 The E3 Ubiquitin Ligase Asb2β is Downregulated in a Mouse Model of Hypertrophic Cardiomyopathy and Targets Desmin for Proteasomal Degradation Journal of Molecular and Cellular Cardiology. Oct, 2015 | Pubmed ID: 26343497 Immunobiology of Fibrin-based Engineered Heart Tissue Stem Cells Translational Medicine. Jun, 2015 | Pubmed ID: 25947338 LQT1-phenotypes in HiPSC: Are We Measuring the Right Thing? Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015 | Pubmed ID: 25795242 Prolonged Action Potentials in HCM-derived IPSC--biology or Artefact? Cardiovascular Research. Apr, 2015 | Pubmed ID: 25691543 Deciphering the MicroRNA Signature of Pathological Cardiac Hypertrophy by Engineered Heart Tissue- and Sequencing-technology Journal of Molecular and Cellular Cardiology. Apr, 2015 | Pubmed ID: 25633833 Modelling Sarcomeric Cardiomyopathies in the Dish: from Human Heart Samples to IPSC Cardiomyocytes Cardiovascular Research. Apr, 2015 | Pubmed ID: 25618410 Assessment of DNA Synthesis in Islet-1⁺ Cells in the Adult Murine Heart Biochemical and Biophysical Research Communications. Jan, 2015 | Pubmed ID: 25450620 Development of Phosphatase Inhibitor-1 Peptides Acting As Indirect Activators of Phosphatase 1 Naunyn-Schmiedeberg's Archives of Pharmacology. Mar, 2015 | Pubmed ID: 25416155 Mybpc3 Gene Therapy for Neonatal Cardiomyopathy Enables Long-term Disease Prevention in Mice Nature Communications. Dec, 2014 | Pubmed ID: 25463264 FHL2 Expression and Variants in Hypertrophic Cardiomyopathy Basic Research in Cardiology. 2014 | Pubmed ID: 25358972 Effects of Proarrhythmic Drugs on Relaxation Time and Beating Pattern in Rat Engineered Heart Tissue Basic Research in Cardiology. 2014 | Pubmed ID: 25209140 The Continuum of Personalized Cardiovascular Medicine: a Position Paper of the European Society of Cardiology European Heart Journal. Dec, 2014 | Pubmed ID: 25148837 Cardiac Arrhythmia Induced by Genetic Silencing of 'funny' (f) Channels is Rescued by GIRK4 Inactivation Nature Communications. Aug, 2014 | Pubmed ID: 25144323 Generation of Strip-format Fibrin-based Engineered Heart Tissue (EHT) Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25070332 Prostaglandin E2 Does Not Attenuate Adrenergic-induced Cardiac Contractile Response Naunyn-Schmiedeberg's Archives of Pharmacology. Oct, 2014 | Pubmed ID: 24974239 Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes PloS One. 2014 | Pubmed ID: 24892553 Functional Improvement and Maturation of Rat and Human Engineered Heart Tissue by Chronic Electrical Stimulation Journal of Molecular and Cellular Cardiology. Sep, 2014 | Pubmed ID: 24852842 Dichloroacetate Prevents Restenosis in Preclinical Animal Models of Vessel Injury Nature. Apr, 2014 | Pubmed ID: 24747400 Myocardial Tissue Engineering: in Vitro Models Cold Spring Harbor Perspectives in Medicine. Mar, 2014 | Pubmed ID: 24591534 Automated Analysis of Contractile Force and Ca2+ Transients in Engineered Heart Tissue American Journal of Physiology. Heart and Circulatory Physiology. May, 2014 | Pubmed ID: 24585781 Cardiac Tissue Engineering: State of the Art Circulation Research. Jan, 2014 | Pubmed ID: 24436431 Paradoxical Effects on Force Generation After Efficient β1-adrenoceptor Knockdown in Reconstituted Heart Tissue The Journal of Pharmacology and Experimental Therapeutics. Apr, 2014 | Pubmed ID: 24431469 In Vitro Perfusion of Engineered Heart Tissue Through Endothelialized Channels Tissue Engineering. Part A. Feb, 2014 | Pubmed ID: 24156346 Melusin Protects from Cardiac Rupture and Improves Functional Remodelling After Myocardial Infarction Cardiovascular Research. Jan, 2014 | Pubmed ID: 24130190 Functional MicroRNA Library Screening Identifies the Hypoxamir MiR-24 As a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization Antioxidants & Redox Signaling. Sep, 2014 | Pubmed ID: 24063572 [Interview by Anne-Katrin Döbler] Deutsche Medizinische Wochenschrift (1946). Nov, 2013 | Pubmed ID: 24350367 B-scan Ultrasonographic Monitoring of Orthotopic Xenografted Plexiform Neurofibroma in Mice In Vivo (Athens, Greece). Nov-Dec, 2013 | Pubmed ID: 24292574 Nfat and MiR-25 Cooperate to Reactivate the Transcription Factor Hand2 in Heart Failure Nature Cell Biology. Nov, 2013 | Pubmed ID: 24161931 Contractile Abnormalities and Altered Drug Response in Engineered Heart Tissue from Mybpc3-targeted Knock-in Mice Journal of Molecular and Cellular Cardiology. Oct, 2013 | Pubmed ID: 23896226 Repair of Mybpc3 MRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy Molecular Therapy. Nucleic Acids. Jul, 2013 | Pubmed ID: 23820890 Phosphodiesterase-2 is Upregulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes Journal of the American College of Cardiology. Jun, 2013 | Pubmed ID: 23810893 Rescue of Cardiomyopathy Through U7snRNA-mediated Exon Skipping in Mybpc3-targeted Knock-in Mice EMBO Molecular Medicine. Jul, 2013 | Pubmed ID: 23716398 Development of a Colorimetric and a Fluorescence Phosphatase-inhibitor Assay Suitable for Drug Discovery Approaches Journal of Biomolecular Screening. Sep, 2013 | Pubmed ID: 23606651 Heterozygous LmnadelK32 Mice Develop Dilated Cardiomyopathy Through a Combined Pathomechanism of Haploinsufficiency and Peptide Toxicity Human Molecular Genetics. Aug, 2013 | Pubmed ID: 23575224 Impact of ANKRD1 Mutations Associated with Hypertrophic Cardiomyopathy on Contraction Parameters of Engineered Heart Tissue Basic Research in Cardiology. May, 2013 | Pubmed ID: 23572067 Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-mediated Calcium Signaling and Arrhythmias in the Heart Evoked by β-adrenergic Stimulation The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23564460 PDE4 in the Human Heart - Major Player or Little Helper? British Journal of Pharmacology. Jun, 2013 | Pubmed ID: 23489196 Parthenogenetic Stem Cells for Tissue-engineered Heart Repair The Journal of Clinical Investigation. Mar, 2013 | Pubmed ID: 23434590 [Personalized Therapy in Cardiology. Biomarkers, Pharmacogenetics and Therapy of Monogenic Diseases] Der Internist. Feb, 2013 | Pubmed ID: 23371262 A Frequent Gene Polymorphism Affecting the Heart-rate Response to Carvedilol Pharmacogenomics. Jan, 2013 | Pubmed ID: 23327570 New Tissue for Failing Hearts European Journal of Heart Failure. Jan, 2013 | Pubmed ID: 23243121 Pharmacological Characterization of 1-nitrosocyclohexyl Acetate, a Long-acting Nitroxyl Donor That Shows Vasorelaxant and Antiaggregatory Effects The Journal of Pharmacology and Experimental Therapeutics. Feb, 2013 | Pubmed ID: 23211362 A Novel Genetic Variant in the Transcription Factor Islet-1 Exerts Gain of Function on Myocyte Enhancer Factor 2C Promoter Activity European Journal of Heart Failure. Mar, 2013 | Pubmed ID: 23152444 Increased Afterload Induces Pathological Cardiac Hypertrophy: a New in Vitro Model Basic Research in Cardiology. Nov, 2012 | Pubmed ID: 23099820 The German Centre for Cardiovascular Research European Heart Journal. May, 2012 | Pubmed ID: 22893891 Progesterone Receptor Variants Associated with the PROGINS Haplotype Exhibit Functional Properties Similar to Those of Wild-type Progesterone Receptor Pharmacogenetics and Genomics. Aug, 2012 | Pubmed ID: 22722322 Increased Myocardial SERCA Expression in Early Type 2 Diabetes Mellitus is Insulin Dependent: In Vivo and in Vitro Data Cardiovascular Diabetology. May, 2012 | Pubmed ID: 22621761 Physiological Aspects of Cardiac Tissue Engineering American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2012 | Pubmed ID: 22582087 Complex Interactions Between Human Myoblasts and the Surrounding 3D Fibrin-based Matrix PloS One. 2012 | Pubmed ID: 22558372 Evidence for FHL1 As a Novel Disease Gene for Isolated Hypertrophic Cardiomyopathy Human Molecular Genetics. Jul, 2012 | Pubmed ID: 22523091 Increased Myofilament Ca2+ Sensitivity and Diastolic Dysfunction As Early Consequences of Mybpc3 Mutation in Heterozygous Knock-in Mice Journal of Molecular and Cellular Cardiology. Jun, 2012 | Pubmed ID: 22465693 Localization of Islet-1-positive Cells in the Healthy and Infarcted Adult Murine Heart Circulation Research. Mar, 2012 | Pubmed ID: 22427341 Defective Proteolytic Systems in Mybpc3-targeted Mice with Cardiac Hypertrophy Basic Research in Cardiology. Jan, 2012 | Pubmed ID: 22189562 Adrenergic Stress Reveals Septal Hypertrophy and Proteasome Impairment in Heterozygous Mybpc3-targeted Knock-in Mice Journal of Muscle Research and Cell Motility. Nov, 2011 | Pubmed ID: 22076249 Human Engineered Heart Tissue As a Versatile Tool in Basic Research and Preclinical Toxicology PloS One. 2011 | Pubmed ID: 22028871 Terminal Differentiation, Advanced Organotypic Maturation, and Modeling of Hypertrophic Growth in Engineered Heart Tissue Circulation Research. Oct, 2011 | Pubmed ID: 21921264 The Beat Goes On: Human Heart Muscle from Pluripotent Stem Cells Circulation Research. Jun, 2011 | Pubmed ID: 21700948 Follistatin-like 1 in Chronic Systolic Heart Failure: a Marker of Left Ventricular Remodeling Circulation. Heart Failure. Sep, 2011 | Pubmed ID: 21622850 The Effect of Mesenchymal Stem Cell Osteoblastic Differentiation on the Mechanical Properties of Engineered Bone-like Tissue Tissue Engineering. Part A. Sep, 2011 | Pubmed ID: 21548844 Titration to Target Dose of Bisoprolol Vs. Carvedilol in Elderly Patients with Heart Failure: the CIBIS-ELD Trial European Journal of Heart Failure. Jun, 2011 | Pubmed ID: 21429992 Phosphatase-1 Inhibitor-1 in Physiological and Pathological β-adrenoceptor Signalling Cardiovascular Research. Aug, 2011 | Pubmed ID: 21354993 Cardiovascular Side Effects of Cancer Therapies: a Position Statement from the Heart Failure Association of the European Society of Cardiology European Journal of Heart Failure. Jan, 2011 | Pubmed ID: 21169385 Engineering Bioartificial Tracheal Tissue Using Hybrid Fibroblast-mesenchymal Stem Cell Cultures in Collagen Hydrogels Interactive Cardiovascular and Thoracic Surgery. Feb, 2011 | Pubmed ID: 21098511 Distinction Between Two Populations of Islet-1-positive Cells in Hearts of Different Murine Strains Stem Cells and Development. Jun, 2011 | Pubmed ID: 20942609 Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load PloS One. 2010 | Pubmed ID: 21151612 MicroRNA-199b Targets the Nuclear Kinase Dyrk1a in an Auto-amplification Loop Promoting Calcineurin/NFAT Signalling Nature Cell Biology. Dec, 2010 | Pubmed ID: 21102440 Is Ryanodine Receptor Phosphorylation Key to the Fight or Flight Response and Heart Failure? The Journal of Clinical Investigation. Dec, 2010 | Pubmed ID: 21099119 The New HNO Donor, 1-nitrosocyclohexyl Acetate, Increases Contractile Force in Normal and β-adrenergically Desensitized Ventricular Myocytes Biochemical and Biophysical Research Communications. Nov, 2010 | Pubmed ID: 20946877 Myomasp/LRRC39, a Heart- and Muscle-specific Protein, is a Novel Component of the Sarcomeric M-band and is Involved in Stretch Sensing Circulation Research. Nov, 2010 | Pubmed ID: 20847312 Phosphatase-1-inhibitor-1: Amplifier or Attenuator of Catecholaminergic Stress? Basic Research in Cardiology. Sep, 2010 | Pubmed ID: 20526608 Development of a Drug Screening Platform Based on Engineered Heart Tissue Circulation Research. Jul, 2010 | Pubmed ID: 20448218 [Vernakalant: a Novel Antiarrhythmic Drug for the Rapid Conversion of Atrial Fibrillation to Sinus Rhythm] Deutsche Medizinische Wochenschrift (1946). May, 2010 | Pubmed ID: 20446233 Myeloperoxidase Acts As a Profibrotic Mediator of Atrial Fibrillation Nature Medicine. Apr, 2010 | Pubmed ID: 20305660 Constitutively Active Phosphatase Inhibitor-1 Improves Cardiac Contractility in Young Mice but is Deleterious After Catecholaminergic Stress and with Aging The Journal of Clinical Investigation. Feb, 2010 | Pubmed ID: 20071777 Atrogin-1 and MuRF1 Regulate Cardiac MyBP-C Levels Via Different Mechanisms Cardiovascular Research. Jan, 2010 | Pubmed ID: 19850579 The Ubiquitin-proteasome System and Nonsense-mediated MRNA Decay in Hypertrophic Cardiomyopathy Cardiovascular Research. Jan, 2010 | Pubmed ID: 19617224 Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-based Myocardial Salvage After Acute Myocardial Infarction Circulation. Sep, 2009 | Pubmed ID: 19752375 Nonsense-mediated MRNA Decay and Ubiquitin-proteasome System Regulate Cardiac Myosin-binding Protein C Mutant Levels in Cardiomyopathic Mice Circulation Research. Jul, 2009 | Pubmed ID: 19590044 A New Polymorphism in Human Calmodulin III Gene Promoter is a Potential Modifier Gene for Familial Hypertrophic Cardiomyopathy European Heart Journal. Jul, 2009 | Pubmed ID: 19429631 Capturing Adenylyl Cyclases As Potential Drug Targets Nature Reviews. Drug Discovery. Apr, 2009 | Pubmed ID: 19337273 Treatment with Atorvastatin Partially Protects the Rat Heart from Harmful Catecholamine Effects Cardiovascular Research. Apr, 2009 | Pubmed ID: 19136528 Beta-adrenergic Stimulation and Myocardial Function in the Failing Heart Heart Failure Reviews. Dec, 2009 | Pubmed ID: 19110970 [Not Available] MMW Fortschritte Der Medizin. Oct, 2008 | Pubmed ID: 27372484 Mechanical Unloading of the Rat Heart Involves Marked Changes in the Protein Kinase-phosphatase Balance Journal of Molecular and Cellular Cardiology. Dec, 2008 | Pubmed ID: 18848565 Activation of Negative Regulators of the Hypoxia-inducible Factor (HIF) Pathway in Human End-stage Heart Failure Biochemical and Biophysical Research Communications. Nov, 2008 | Pubmed ID: 18782560 Unloaded Rat Hearts in Vivo Express a Hypertrophic Phenotype of Cardiac Repolarization Journal of Molecular and Cellular Cardiology. Nov, 2008 | Pubmed ID: 18721926 Phosphatase Inhibitor-1-deficient Mice Are Protected from Catecholamine-induced Arrhythmias and Myocardial Hypertrophy Cardiovascular Research. Dec, 2008 | Pubmed ID: 18689792 Bisoprolol Vs. Carvedilol in Elderly Patients with Heart Failure: Rationale and Design of the CIBIS-ELD Trial Clinical Research in Cardiology : Official Journal of the German Cardiac Society. Sep, 2008 | Pubmed ID: 18542839 Angiotensin II and Myosin Light-chain Phosphorylation Contribute to the Stretch-induced Slow Force Response in Human Atrial Myocardium Cardiovascular Research. Sep, 2008 | Pubmed ID: 18503051 The Slow Force Response to Stretch in Atrial and Ventricular Myocardium from Human Heart: Functional Relevance and Subcellular Mechanisms Progress in Biophysics and Molecular Biology. Jun-Jul, 2008 | Pubmed ID: 18466959 Beta-adrenergic Signaling in Heart Failure-adapt or Die Nature Medicine. May, 2008 | Pubmed ID: 18463653 ATP-binding Cassette Transporters in Human Heart Failure Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2008 | Pubmed ID: 18392808 Inhibition of Aldehyde Dehydrogenase Type 2 Attenuates Vasodilatory Action of Nitroglycerin in Human Veins FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2008 | Pubmed ID: 18272654 Thyroid Hormone Regulates Developmental Titin Isoform Transitions Via the Phosphatidylinositol-3-kinase/ AKT Pathway Circulation Research. Feb, 2008 | Pubmed ID: 18096819 Real-time Myocardial Contrast Echocardiography for Assessing Perfusion and Function in Healthy and Infarcted Wistar Rats Ultrasound in Medicine & Biology. Jan, 2008 | Pubmed ID: 17854980 Cardiac Tissue Engineering: a Clinical Perspective Future Cardiology. Jul, 2007 | Pubmed ID: 21526914 Long-term Beta-adrenergic Stimulation Leads to Downregulation of Protein Phosphatase Inhibitor-1 in the Heart European Journal of Heart Failure. Nov, 2007 | Pubmed ID: 17921049 Development of a Biological Ventricular Assist Device: Preliminary Data from a Small Animal Model Circulation. Sep, 2007 | Pubmed ID: 17846298 Cardiac Myosin-binding Protein C is Required for Complete Relaxation in Intact Myocytes Circulation Research. Oct, 2007 | Pubmed ID: 17823372 Adenovirus-delivered Short Hairpin RNA Targeting PKCalpha Improves Contractile Function in Reconstituted Heart Tissue Journal of Molecular and Cellular Cardiology. Sep, 2007 | Pubmed ID: 17628588 Decreased Phosphorylation Levels of Cardiac Myosin-binding Protein-C in Human and Experimental Heart Failure Journal of Molecular and Cellular Cardiology. Aug, 2007 | Pubmed ID: 17560599 Reproducibility of Transthoracic Echocardiography in Small Animals Using Clinical Equipment Coronary Artery Disease. Jun, 2007 | Pubmed ID: 17496492 Embryonic Stem Cells for Cardiac Muscle Engineering Trends in Cardiovascular Medicine. May, 2007 | Pubmed ID: 17482096 Regulation of Cardiac CAMP Synthesis and Contractility by Nucleoside Diphosphate Kinase B/G Protein Beta Gamma Dimer Complexes Circulation Research. Apr, 2007 | Pubmed ID: 17363702 Reduced Contractile Response to Alpha1-adrenergic Stimulation in Atria from Mice with Chronic Cardiac Calmodulin Kinase II Inhibition Journal of Molecular and Cellular Cardiology. Mar, 2007 | Pubmed ID: 17292391 The 2988G>A Polymorphism Affects Splicing of a CYP2D6 Minigene Clinical Pharmacology and Therapeutics. Nov, 2006 | Pubmed ID: 17112815 High-dose Methotrexate in Pediatric Acute Lymphoblastic Leukemia: Impact of ABCC2 Polymorphisms on Plasma Concentrations Clinical Pharmacology and Therapeutics. Nov, 2006 | Pubmed ID: 17112803 Molecular Determinants of Altered Ca2+ Handling in Human Chronic Atrial Fibrillation Circulation. Aug, 2006 | Pubmed ID: 16894034 Optimizing Engineered Heart Tissue for Therapeutic Applications As Surrogate Heart Muscle Circulation. Jul, 2006 | Pubmed ID: 16820649 The MLCK-mediated Alpha1-adrenergic Inotropic Effect in Atrial Myocardium is Negatively Modulated by PKCepsilon Signaling British Journal of Pharmacology. Aug, 2006 | Pubmed ID: 16783412 Role of Calcineurin and Protein Phosphatase-2A in the Regulation of Phosphatase Inhibitor-1 in Cardiac Myocytes Biochemical and Biophysical Research Communications. Aug, 2006 | Pubmed ID: 16774736 Heart Muscle Engineering: an Update on Cardiac Muscle Replacement Therapy Cardiovascular Research. Aug, 2006 | Pubmed ID: 16697358 Engineered Heart Tissue Grafts Improve Systolic and Diastolic Function in Infarcted Rat Hearts Nature Medicine. Apr, 2006 | Pubmed ID: 16582915 Electrical Coupling of Cardiac Myocyte Cell Sheets to the Heart Circulation Research. Mar, 2006 | Pubmed ID: 16543504 Atorvastatin Desensitizes Beta-adrenergic Signaling in Cardiac Myocytes Via Reduced Isoprenylation of G-protein Gamma-subunits FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2006 | Pubmed ID: 16467371 Alterations of the Preproenkephalin System in Cardiac Hypertrophy and Its Role in Atrioventricular Conduction Cardiovascular Research. Feb, 2006 | Pubmed ID: 16376326 Engineering Myocardial Tissue Circulation Research. Dec, 2005 | Pubmed ID: 16339494 Questioning the Relevance of Circulating Cardiac Progenitor Cells in Cardiac Regeneration Cardiovascular Research. Dec, 2005 | Pubmed ID: 16253213 Endothelin-1 and Isoprenaline Co-stimulation Causes Contractile Failure Which is Partially Reversed by MEK Inhibition Cardiovascular Research. Dec, 2005 | Pubmed ID: 16040022 Differential Functional Effects of Two 5-HT4 Receptor Isoforms in Adult Cardiomyocytes Journal of Molecular and Cellular Cardiology. Aug, 2005 | Pubmed ID: 15950987 Impairment of the Ubiquitin-proteasome System by Truncated Cardiac Myosin Binding Protein C Mutants Cardiovascular Research. Apr, 2005 | Pubmed ID: 15769446 Key Role of Myosin Light Chain (MLC) Kinase-mediated MLC2a Phosphorylation in the Alpha 1-adrenergic Positive Inotropic Effect in Human Atrium Cardiovascular Research. Jan, 2005 | Pubmed ID: 15621049 [Beta Blockers in Cardiac Insufficiency. When, How Much and Which Substance] Medizinische Monatsschrift Für Pharmazeuten. Dec, 2004 | Pubmed ID: 15646690 Effect of Amiodarone on the Plasma Levels of Metoprolol The American Journal of Cardiology. Nov, 2004 | Pubmed ID: 15541258 CYP2D6 Genotype: Impact on Adverse Effects and Nonresponse During Treatment with Antidepressants-a Pilot Study Clinical Pharmacology and Therapeutics. May, 2004 | Pubmed ID: 15116051 Ouabain Treatment is Associated with Upregulation of Phosphatase Inhibitor-1 and Na+/Ca(2+)-exchanger and Beta-adrenergic Sensitization in Rat Hearts Biochemical and Biophysical Research Communications. May, 2004 | Pubmed ID: 15110776 S100A1 Gene Transfer: a Strategy to Strengthen Engineered Cardiac Grafts The Journal of Gene Medicine. Apr, 2004 | Pubmed ID: 15079813 Effects of Chronic Endothelin-1 Stimulation on Cardiac Myocyte Contractile Function American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2004 | Pubmed ID: 15020300 Formation of Molecular Complexes by N-methyl-D-aspartate Receptor Subunit NR2B and Ryanodine Receptor 2 in Neonatal Rat Myocard The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 15010472 Human Homozygous R403W Mutant Cardiac Myosin Presents Disproportionate Enhancement of Mechanical and Enzymatic Properties Journal of Molecular and Cellular Cardiology. Mar, 2004 | Pubmed ID: 15010274 Decreased Protein and Phosphorylation Level of the Protein Phosphatase Inhibitor-1 in Failing Human Hearts Cardiovascular Research. Jan, 2004 | Pubmed ID: 14732205 Engineered Heart Tissue for Regeneration of Diseased Hearts Biomaterials. Apr, 2004 | Pubmed ID: 14697865 Norepinephrine Upregulates Vascular Endothelial Growth Factor in Rat Cardiac Myocytes by a Paracrine Mechanism Angiogenesis. 2003 | Pubmed ID: 15166499 Inhibitory G-proteins and Their Role in Desensitization of the Adenylyl Cyclase Pathway in Heart Failure Cardiovascular Research. Dec, 2003 | Pubmed ID: 14659793 Tissue Engineering of Aortic Heart Valves Cardiovascular Research. Dec, 2003 | Pubmed ID: 14659789 What is the Role of Beta-adrenergic Signaling in Heart Failure? Circulation Research. Nov, 2003 | Pubmed ID: 14615493 Differential Coupling of M-cholinoceptors to Gi/Go-proteins in Failing Human Myocardium Journal of Molecular and Cellular Cardiology. Oct, 2003 | Pubmed ID: 14519434 Heme Oxygenase-1 and Its Reaction Product, Carbon Monoxide, Prevent Inflammation-related Apoptotic Liver Damage in Mice Hepatology (Baltimore, Md.). Oct, 2003 | Pubmed ID: 14512878 Beta-adrenergic Stimulation Induces Cardiac Ankyrin Repeat Protein Expression: Involvement of Protein Kinase A and Calmodulin-dependent Kinase Cardiovascular Research. Sep, 2003 | Pubmed ID: 14499857 Cardiac Tissue Engineering for Replacement Therapy Heart Failure Reviews. Jul, 2003 | Pubmed ID: 12878835 Overexpression of Wild-type Galpha(i)-2 Suppresses Beta-adrenergic Signaling in Cardiac Myocytes FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003 | Pubmed ID: 12631586 Evidence for Protein Phosphatase Inhibitor-1 Playing an Amplifier Role in Beta-adrenergic Signaling in Cardiac Myocytes FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003 | Pubmed ID: 12514122 3D Engineered Heart Tissue for Replacement Therapy Basic Research in Cardiology. 2002 | Pubmed ID: 12479248 Increased Frequency of Cytochrome P450 2D6 Poor Metabolizers Among Patients with Metoprolol-associated Adverse Effects Clinical Pharmacology and Therapeutics. Oct, 2002 | Pubmed ID: 12386645 Cardiac Grafting of Engineered Heart Tissue in Syngenic Rats Circulation. Sep, 2002 | Pubmed ID: 12354725 Augmented Expression of Cardiotrophin-1 in Failing Human Hearts is Accompanied by Diminished Glycoprotein 130 Receptor Protein Abundance Circulation. Sep, 2002 | Pubmed ID: 12234945 Cardiac Tissue Engineering Transplant Immunology. May, 2002 | Pubmed ID: 12180846 Expression of Ten RGS Proteins in Human Myocardium: Functional Characterization of an Upregulation of RGS4 in Heart Failure Cardiovascular Research. Sep, 2002 | Pubmed ID: 12176127 Effect of the CYP2D6 Genotype on Metoprolol Metabolism Persists During Long-term Treatment Pharmacogenetics. Aug, 2002 | Pubmed ID: 12172215 Intracellular Beta-blockade: Overexpression of Galpha(i2) Depresses the Beta-adrenergic Response in Intact Myocardium Cardiovascular Research. Aug, 2002 | Pubmed ID: 12123769 Cardiac Ankyrin Repeat Protein, a Negative Regulator of Cardiac Gene Expression, is Augmented in Human Heart Failure Biochemical and Biophysical Research Communications. May, 2002 | Pubmed ID: 12054667 Specific Beta(2)AR Blocker ICI 118,551 Actively Decreases Contraction Through a G(i)-coupled Form of the Beta(2)AR in Myocytes from Failing Human Heart Circulation. May, 2002 | Pubmed ID: 12034656 Physiological Antagonism Between Ventricular Beta 1-adrenoceptors and Alpha 1-adrenoceptors but No Evidence for Beta 2- and Beta 3-adrenoceptor Function in Murine Heart British Journal of Pharmacology. May, 2002 | Pubmed ID: 12010770 Inhibition of Left Ventricular Fibrosis by Tranilast in Rats with Renovascular Hypertension Journal of Hypertension. Apr, 2002 | Pubmed ID: 11910312 Activation of the Cardiac Endothelin System in Left Ventricular Hypertrophy Before Onset of Heart Failure in TG(mREN2)27 Rats Cardiovascular Research. Feb, 2002 | Pubmed ID: 11827687 التكيف المغناطيسي للحمولة اللاحقة في أنسجة القلب المهندسة Benjamin Becker*1,2, Marita L. Rodriguez*1,2, Tessa R. Werner1,2, Justus Stenzig1,2, Thomas Eschenhagen1,2, Marc N. Hirt1,2 1Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 2DZHK (German Centre for Cardiovascular Research) JoVE 60811 Developmental Biology غرس المستمدة من هيبسك بقع عضلة القلب بعد "إصابة احتشاء عضلة القلب" في "نموذج خنزير غينيا" Liesa Castro1,2, Birgit Geertz3, Marina Reinsch2,3, Bülent Aksehirlioglu3, Arne Hansen2,3, Thomas Eschenhagen2,3, Hermann Reichenspurner1,2, Florian Weinberger*2,3, Simon Pecha*1,2 1Department of Cardiovascular Surgery, University Heart Center Hamburg, 2partner site Hamburg/Kiel/Lübeck, German Centre for Cardiovascular Research (DZHK), 3Department of Experimental Pharmacology and Toxicology, Cardiovascular ResearchCenter, University Medical Center Hamburg-Eppendorf JoVE 58810 Medicine تحليل الآلي تقلص الإنسان المهندسة القلب الأنسجة للفحص القلب سلامة الأدوية Ingra Mannhardt1, Umber Saleem1, Anika Benzin1, Thomas Schulze1, Birgit Klampe1, Thomas Eschenhagen1, Arne Hansen1 1Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf and DZHK (German Center for Cardiovascular Research) JoVE 55461 Bioengineering التصوير تلألؤ بيولوجي لتقييم الاستجابات المناعية عقب زرع أنسجة القلب المهندسة (EHT) Lenard Conradi1,2, Christiane Pahrmann1, Stephanie Schmidt1, Tobias Deuse1,3, Arne Hansen2, Alexandra Eder2, Hermann Reichenspurner1, Robert C. Robbins3, Thomas Eschenhagen2, Sonja Schrepfer1,3 1Transplant and Stem Cell Immunobiology Lab (TSI) and CVRC, University Hospital Hamburg, University Heart Center Hamburg, 2Department of Experimental and Clinical Pharmacology and Toxicology, University Heart Center Hamburg, 3CT Surgery, Stanford University School of Medicine JoVE 2605 Bioengineering
التكيف المغناطيسي للحمولة اللاحقة في أنسجة القلب المهندسة Benjamin Becker*1,2, Marita L. Rodriguez*1,2, Tessa R. Werner1,2, Justus Stenzig1,2, Thomas Eschenhagen1,2, Marc N. Hirt1,2 1Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 2DZHK (German Centre for Cardiovascular Research) JoVE 60811 Developmental Biology
غرس المستمدة من هيبسك بقع عضلة القلب بعد "إصابة احتشاء عضلة القلب" في "نموذج خنزير غينيا" Liesa Castro1,2, Birgit Geertz3, Marina Reinsch2,3, Bülent Aksehirlioglu3, Arne Hansen2,3, Thomas Eschenhagen2,3, Hermann Reichenspurner1,2, Florian Weinberger*2,3, Simon Pecha*1,2 1Department of Cardiovascular Surgery, University Heart Center Hamburg, 2partner site Hamburg/Kiel/Lübeck, German Centre for Cardiovascular Research (DZHK), 3Department of Experimental Pharmacology and Toxicology, Cardiovascular ResearchCenter, University Medical Center Hamburg-Eppendorf JoVE 58810 Medicine
تحليل الآلي تقلص الإنسان المهندسة القلب الأنسجة للفحص القلب سلامة الأدوية Ingra Mannhardt1, Umber Saleem1, Anika Benzin1, Thomas Schulze1, Birgit Klampe1, Thomas Eschenhagen1, Arne Hansen1 1Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf and DZHK (German Center for Cardiovascular Research) JoVE 55461 Bioengineering
التصوير تلألؤ بيولوجي لتقييم الاستجابات المناعية عقب زرع أنسجة القلب المهندسة (EHT) Lenard Conradi1,2, Christiane Pahrmann1, Stephanie Schmidt1, Tobias Deuse1,3, Arne Hansen2, Alexandra Eder2, Hermann Reichenspurner1, Robert C. Robbins3, Thomas Eschenhagen2, Sonja Schrepfer1,3 1Transplant and Stem Cell Immunobiology Lab (TSI) and CVRC, University Hospital Hamburg, University Heart Center Hamburg, 2Department of Experimental and Clinical Pharmacology and Toxicology, University Heart Center Hamburg, 3CT Surgery, Stanford University School of Medicine JoVE 2605 Bioengineering
