Thomas Eschenhagen Institute of Experimental Pharmacology and Toxicology University Medical Center Hamburg-Eppendorf Biography Publications Institution JoVE Articles Thomas Eschenhagen has not added a biography. If you are Thomas Eschenhagen and would like to personalize this page please email our Author Liaison for assistance. Publications Toward Standardization of Echocardiography for the Evaluation of Left Ventricular Function in Adult Rodents: a Position Paper of the ESC Working Group on Myocardial Function Cardiovascular Research. May, 2020 | Pubmed ID: 32365197 Aging-regulated Anti-apoptotic Long Non-coding RNA Sarrah Augments Recovery from Acute Myocardial Infarction Nature Communications. Apr, 2020 | Pubmed ID: 32341350 An Epidemiological Study Exploring a Possible Impact of Treatment with ACE Inhibitors or Angiotensin Receptor Blockers on ACE2 Plasma Concentrations Journal of Molecular and Cellular Cardiology. Apr, 2020 | Pubmed ID: 32268149 Regulation of I and Force by PDEs in Human-induced Pluripotent Stem Cell-derived Cardiomyocytes British Journal of Pharmacology. Feb, 2020 | Pubmed ID: 32092149 Case Report On: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes-An Artifact by Big Conductance Calcium Activated Potassium Current (I) Cells. Jan, 2020 | Pubmed ID: 31968557 Force and Calcium Transients Analysis in Human Engineered Heart Tissues Reveals Positive Force-Frequency Relation at Physiological Frequency Stem Cell Reports. Feb, 2020 | Pubmed ID: 31956082 Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive? Annual Review of Pharmacology and Toxicology. 01, 2020 | Pubmed ID: 31506008 Human Pluripotent Stem Cell-derived Cardiomyocytes for Studying Energy Metabolism Biochimica Et Biophysica Acta. Molecular Cell Research. Mar, 2020 | Pubmed ID: 30954570 Phosphomimetic Cardiac Myosin-binding Protein C Partially Rescues a Cardiomyopathy Phenotype in Murine Engineered Heart Tissue Scientific Reports. Dec, 2019 | Pubmed ID: 31796859 Disease Modeling of a Mutation in α-actinin 2 Guides Clinical Therapy in Hypertrophic Cardiomyopathy EMBO Molecular Medicine. 12, 2019 | Pubmed ID: 31680489 A Magnetics-based Approach for Fine-tuning Afterload in Engineered Heart Tissues ACS Biomaterials Science & Engineering. Jul, 2019 | Pubmed ID: 31637285 Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis Molecular Therapy. Nucleic Acids. Dec, 2019 | Pubmed ID: 31634682 Chronic Intermittent Tachypacing by an Optogenetic Approach Induces Arrhythmia Vulnerability in Human Engineered Heart Tissue Cardiovascular Research. Oct, 2019 | Pubmed ID: 31598634 Simultaneous Measurement of Excitation-contraction Coupling Parameters Identifies Mechanisms Underlying Contractile Responses of HiPSC-derived Cardiomyocytes Nature Communications. 09, 2019 | Pubmed ID: 31541103 Blockade of MiR-140-3p Prevents Functional Deterioration in Afterload-enhanced Engineered Heart Tissue Scientific Reports. 08, 2019 | Pubmed ID: 31391475 Author Correction: Differentiation of Cardiomyocytes and Generation of Human Engineered Heart Tissue Nature Protocols. Sep, 2019 | Pubmed ID: 31384055 Human IPS Cell-derived Engineered Heart Tissue Does Not Affect Ventricular Arrhythmias in a Guinea Pig Cryo-injury Model Scientific Reports. 07, 2019 | Pubmed ID: 31285568 Analysis of Fibrosis in Control or Pressure Overloaded Rat Hearts After Mechanical Unloading by Heterotopic Heart Transplantation Scientific Reports. 04, 2019 | Pubmed ID: 30952943 Dissecting HiPSC-CM Pacemaker Function in a Cardiac Organoid Model Biomaterials. Jun, 2019 | Pubmed ID: 30933775 Heart Repair With Myocytes Circulation Research. 03, 2019 | Pubmed ID: 30870126 Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors ChemMedChem. 04, 2019 | Pubmed ID: 30768867 ESC Working Group on Cellular Biology of the Heart: Position Paper for Cardiovascular Research: Tissue Engineering Strategies Combined with Cell Therapies for Cardiac Repair in Ischaemic Heart Disease and Heart Failure Cardiovascular Research. 03, 2019 | Pubmed ID: 30657875 Mechanistic Role of the CREB-regulated Transcription Coactivator 1 in Cardiac Hypertrophy Journal of Molecular and Cellular Cardiology. Feb, 2019 | Pubmed ID: 30521840 Piezo-bending Actuators for Isometric or Auxotonic Contraction Analysis of Engineered Heart Tissue Journal of Tissue Engineering and Regenerative Medicine. 01, 2019 | Pubmed ID: 30334614 Treatments Targeting Inotropy European Heart Journal. Nov, 2019 | Pubmed ID: 30295807 Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium Stem Cell Reports. Dec, 2018 | Pubmed ID: 30416051 Normalization of Force to Muscle Cross-sectional Area: A Helpful Attempt to Reduce Data Scattering in Contractility Studies? Acta Physiologica (Oxford, England). 12, 2018 | Pubmed ID: 30338659 Cardiomyopathy Phenotypes in Human-induced Pluripotent Stem Cell-derived Cardiomyocytes-a Systematic Review Pflugers Archiv : European Journal of Physiology. Oct, 2018 | Pubmed ID: 30324321 Satellite Cells Delivered in Their Niche Efficiently Generate Functional Myotubes in Three-dimensional Cell Culture PloS One. 2018 | Pubmed ID: 30222770 Rat Atrial Engineered Heart Tissue: a New in Vitro Model to Study Atrial Biology Basic Research in Cardiology. 09, 2018 | Pubmed ID: 30178427 From Basic Science to High Performance Medicine European Heart Journal. Aug, 2018 | Pubmed ID: 30165623 Exaggerated Cardiotoxicity of Sunitinib in Stressed 3-Dimensional Heart Muscles JACC. Basic to Translational Science. Apr, 2018 | Pubmed ID: 30062213 Clonal Dynamics Studied in Cultured Induced Pluripotent Stem Cells Reveal Major Growth Imbalances Within a Few Weeks Stem Cell Research & Therapy. 06, 2018 | Pubmed ID: 29914569 No Effect of Thymosin Beta-4 on the Expression of the Transcription Factor Islet-1 in the Adult Murine Heart Pharmacology Research & Perspectives. 06, 2018 | Pubmed ID: 29864245 Pharmacological Inhibition of DNA Methylation Attenuates Pressure Overload-induced Cardiac Hypertrophy in Rats Journal of Molecular and Cellular Cardiology. Jul, 2018 | Pubmed ID: 29792884 CRISPR/Cas9 Editing in Human Pluripotent Stem Cell-cardiomyocytes Highlights Arrhythmias, Hypocontractility, and Energy Depletion As Potential Therapeutic Targets for Hypertrophic Cardiomyopathy European Heart Journal. 11, 2018 | Pubmed ID: 29741611 Three-Dimensional Human IPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering Cell Reports. Apr, 2018 | Pubmed ID: 29669293 A New Concept of Fibroblast Dynamics in Post-myocardial Infarction Remodeling The Journal of Clinical Investigation. 05, 2018 | Pubmed ID: 29664015 [Cardiology 2018 : From Basic Science to High Efficiency Medicine] Herz. Mar, 2018 | Pubmed ID: 29516153 Contractile Work Contributes to Maturation of Energy Metabolism in HiPSC-Derived Cardiomyocytes Stem Cell Reports. 03, 2018 | Pubmed ID: 29503093 Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of HiPSC-Derived Cardiomyocytes Stem Cell Reports. 03, 2018 | Pubmed ID: 29429959 MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo Circulation Research. Feb, 2018 | Pubmed ID: 29282212 Cardiovascular Research in Germany Circulation Research. 08, 2017 | Pubmed ID: 28819038 Prominent Differences in Left Ventricular Performance and Myocardial Properties Between Right Ventricular and Left Ventricular-based Pacing Modes in Rats Scientific Reports. 07, 2017 | Pubmed ID: 28725029 Human IPSC-derived Cardiomyocytes Cultured in 3D Engineered Heart Tissue Show Physiological Upstroke Velocity and Sodium Current Density Scientific Reports. Jul, 2017 | Pubmed ID: 28710467 Cardiomyocyte Regeneration: A Consensus Statement Circulation. 08, 2017 | Pubmed ID: 28684531 Evaluation of MYBPC3 Trans-Splicing and Gene Replacement As Therapeutic Options in Human IPSC-Derived Cardiomyocytes Molecular Therapy. Nucleic Acids. Jun, 2017 | Pubmed ID: 28624223 Differentiation of Cardiomyocytes and Generation of Human Engineered Heart Tissue Nature Protocols. Jun, 2017 | Pubmed ID: 28492526 Blinded Contractility Analysis in HiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae Toxicological Sciences : an Official Journal of the Society of Toxicology. 07, 2017 | Pubmed ID: 28453742 Engineering Cardiac Muscle Tissue: A Maturating Field of Research Circulation Research. Apr, 2017 | Pubmed ID: 28450366 Thymosin β4 Improves Differentiation and Vascularization of EHTs Stem Cells International. 2017 | Pubmed ID: 28191018 Diltiazem Prevents Stress-induced Contractile Deficits in Cardiomyocytes, but Does Not Reverse the Cardiomyopathy Phenotype in Mybpc3-knock-in Mice The Journal of Physiology. Jan, 2017 | Pubmed ID: 28090637 Epigallocatechin-3-Gallate Accelerates Relaxation and Ca(2+) Transient Decay and Desensitizes Myofilaments in Healthy and Mybpc3-Targeted Knock-in Cardiomyopathic Mice Frontiers in Physiology. 2016 | Pubmed ID: 27994558 Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation PloS One. 2016 | Pubmed ID: 27875570 Cardiac Repair in Guinea Pigs with Human Engineered Heart Tissue from Induced Pluripotent Stem Cells Science Translational Medicine. Nov, 2016 | Pubmed ID: 27807283 Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions Frontiers in Pharmacology. 2016 | Pubmed ID: 27672365 Is Stimulation of Cardiomyocyte Renewal a Facette of Reversible Catecholamine Toxicity? Circulation Research. Sep, 2016 | Pubmed ID: 27635079 Exogenous Nitric Oxide Protects Human Embryonic Stem Cell-Derived Cardiomyocytes Against Ischemia/Reperfusion Injury Oxidative Medicine and Cellular Longevity. 2016 | Pubmed ID: 27403231 Block of Na(+)/Ca(2+) Exchanger by SEA0400 in Human Right Atrial Preparations from Patients in Sinus Rhythm and in Atrial Fibrillation European Journal of Pharmacology. Oct, 2016 | Pubmed ID: 27373849 Outcomes of Patients in Long-Term Opioid Maintenance Treatment Substance Use & Misuse. Sep, 2016 | Pubmed ID: 27355105 Human Engineered Heart Tissue: Analysis of Contractile Force Stem Cell Reports. Jul, 2016 | Pubmed ID: 27211213 Comparison of the Effects of a Truncating and a Missense MYBPC3 Mutation on Contractile Parameters of Engineered Heart Tissue Journal of Molecular and Cellular Cardiology. Aug, 2016 | Pubmed ID: 27108529 Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: Cell-based Therapies for Myocardial Repair and Regeneration in Ischemic Heart Disease and Heart Failure European Heart Journal. Apr, 2016 | Pubmed ID: 27055812 Ataxin-10 is Part of a Cachexokine Cocktail Triggering Cardiac Metabolic Dysfunction in Cancer Cachexia Molecular Metabolism. Feb, 2016 | Pubmed ID: 26909315 Myocardial Tissue Engineering for Cardiac Repair The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2016 | Pubmed ID: 26856673 A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation PloS One. 2016 | Pubmed ID: 26841021 Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue PloS One. 2016 | Pubmed ID: 26840448 S-glutathiolation Impairs Phosphoregulation and Function of Cardiac Myosin-binding Protein C in Human Heart Failure FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2016 | Pubmed ID: 26839380 Spontaneous Formation of Extensive Vessel-Like Structures in Murine Engineered Heart Tissue Tissue Engineering. Part A. Feb, 2016 | Pubmed ID: 26763667 DNA Methylation in an Engineered Heart Tissue Model of Cardiac Hypertrophy: Common Signatures and Effects of DNA Methylation Inhibitors Basic Research in Cardiology. Jan, 2016 | Pubmed ID: 26680771 Knock-out of Nexilin in Mice Leads to Dilated Cardiomyopathy and Endomyocardial Fibroelastosis Basic Research in Cardiology. Jan, 2016 | Pubmed ID: 26659360 Heart Regeneration Biochimica Et Biophysica Acta. Jul, 2016 | Pubmed ID: 26597703 General Practitioners' Adherence to Chronic Heart Failure Guidelines Regarding Medication: the GP-HF Study Clinical Research in Cardiology : Official Journal of the German Cardiac Society. May, 2016 | Pubmed ID: 26552905 Ranolazine Antagonizes Catecholamine-induced Dysfunction in Isolated Cardiomyocytes, but Lacks Long-term Therapeutic Effects in Vivo in a Mouse Model of Hypertrophic Cardiomyopathy Cardiovascular Research. Jan, 2016 | Pubmed ID: 26531128 Pharmacokinetics of the Experimental Non-Nucleosidic DNA Methyl Transferase Inhibitor N-Phthalyl-L-Tryptophan (RG 108) in Rats Basic & Clinical Pharmacology & Toxicology. May, 2016 | Pubmed ID: 26525153 Human Engineered Heart Tissue As a Model System for Drug Testing Advanced Drug Delivery Reviews. Jan, 2016 | Pubmed ID: 26026976 I-1-deficiency Negatively Impacts Survival in a Cardiomyopathy Mouse Model International Journal of Cardiology. Heart & Vasculature. Sep, 2015 | Pubmed ID: 28785686 β 1 Adrenoceptor Antagonistic Effects of the Supposedly Selective β 2 Adrenoceptor Antagonist ICI 118,551 on the Positive Inotropic Effect of Adrenaline in Murine Hearts Pharmacology Research & Perspectives. Oct, 2015 | Pubmed ID: 26516580 Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization Journal of the American College of Cardiology. Nov, 2015 | Pubmed ID: 26516004 The E3 Ubiquitin Ligase Asb2β is Downregulated in a Mouse Model of Hypertrophic Cardiomyopathy and Targets Desmin for Proteasomal Degradation Journal of Molecular and Cellular Cardiology. Oct, 2015 | Pubmed ID: 26343497 Immunobiology of Fibrin-based Engineered Heart Tissue Stem Cells Translational Medicine. Jun, 2015 | Pubmed ID: 25947338 LQT1-phenotypes in HiPSC: Are We Measuring the Right Thing? Proceedings of the National Academy of Sciences of the United States of America. Apr, 2015 | Pubmed ID: 25795242 Prolonged Action Potentials in HCM-derived IPSC--biology or Artefact? Cardiovascular Research. Apr, 2015 | Pubmed ID: 25691543 Deciphering the MicroRNA Signature of Pathological Cardiac Hypertrophy by Engineered Heart Tissue- and Sequencing-technology Journal of Molecular and Cellular Cardiology. Apr, 2015 | Pubmed ID: 25633833 Modelling Sarcomeric Cardiomyopathies in the Dish: from Human Heart Samples to IPSC Cardiomyocytes Cardiovascular Research. Apr, 2015 | Pubmed ID: 25618410 Assessment of DNA Synthesis in Islet-1⁺ Cells in the Adult Murine Heart Biochemical and Biophysical Research Communications. Jan, 2015 | Pubmed ID: 25450620 Development of Phosphatase Inhibitor-1 Peptides Acting As Indirect Activators of Phosphatase 1 Naunyn-Schmiedeberg's Archives of Pharmacology. Mar, 2015 | Pubmed ID: 25416155 Mybpc3 Gene Therapy for Neonatal Cardiomyopathy Enables Long-term Disease Prevention in Mice Nature Communications. Dec, 2014 | Pubmed ID: 25463264 FHL2 Expression and Variants in Hypertrophic Cardiomyopathy Basic Research in Cardiology. 2014 | Pubmed ID: 25358972 Effects of Proarrhythmic Drugs on Relaxation Time and Beating Pattern in Rat Engineered Heart Tissue Basic Research in Cardiology. 2014 | Pubmed ID: 25209140 The Continuum of Personalized Cardiovascular Medicine: a Position Paper of the European Society of Cardiology European Heart Journal. Dec, 2014 | Pubmed ID: 25148837 Cardiac Arrhythmia Induced by Genetic Silencing of 'funny' (f) Channels is Rescued by GIRK4 Inactivation Nature Communications. Aug, 2014 | Pubmed ID: 25144323 Generation of Strip-format Fibrin-based Engineered Heart Tissue (EHT) Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25070332 Prostaglandin E2 Does Not Attenuate Adrenergic-induced Cardiac Contractile Response Naunyn-Schmiedeberg's Archives of Pharmacology. Oct, 2014 | Pubmed ID: 24974239 Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes PloS One. 2014 | Pubmed ID: 24892553 Functional Improvement and Maturation of Rat and Human Engineered Heart Tissue by Chronic Electrical Stimulation Journal of Molecular and Cellular Cardiology. Sep, 2014 | Pubmed ID: 24852842 Dichloroacetate Prevents Restenosis in Preclinical Animal Models of Vessel Injury Nature. Apr, 2014 | Pubmed ID: 24747400 Myocardial Tissue Engineering: in Vitro Models Cold Spring Harbor Perspectives in Medicine. Mar, 2014 | Pubmed ID: 24591534 Automated Analysis of Contractile Force and Ca2+ Transients in Engineered Heart Tissue American Journal of Physiology. Heart and Circulatory Physiology. May, 2014 | Pubmed ID: 24585781 Cardiac Tissue Engineering: State of the Art Circulation Research. Jan, 2014 | Pubmed ID: 24436431 Paradoxical Effects on Force Generation After Efficient β1-adrenoceptor Knockdown in Reconstituted Heart Tissue The Journal of Pharmacology and Experimental Therapeutics. Apr, 2014 | Pubmed ID: 24431469 In Vitro Perfusion of Engineered Heart Tissue Through Endothelialized Channels Tissue Engineering. Part A. Feb, 2014 | Pubmed ID: 24156346 Melusin Protects from Cardiac Rupture and Improves Functional Remodelling After Myocardial Infarction Cardiovascular Research. Jan, 2014 | Pubmed ID: 24130190 Functional MicroRNA Library Screening Identifies the Hypoxamir MiR-24 As a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization Antioxidants & Redox Signaling. Sep, 2014 | Pubmed ID: 24063572 [Interview by Anne-Katrin Döbler] Deutsche Medizinische Wochenschrift (1946). Nov, 2013 | Pubmed ID: 24350367 B-scan Ultrasonographic Monitoring of Orthotopic Xenografted Plexiform Neurofibroma in Mice In Vivo (Athens, Greece). Nov-Dec, 2013 | Pubmed ID: 24292574 Nfat and MiR-25 Cooperate to Reactivate the Transcription Factor Hand2 in Heart Failure Nature Cell Biology. Nov, 2013 | Pubmed ID: 24161931 Contractile Abnormalities and Altered Drug Response in Engineered Heart Tissue from Mybpc3-targeted Knock-in Mice Journal of Molecular and Cellular Cardiology. Oct, 2013 | Pubmed ID: 23896226 Repair of Mybpc3 MRNA by 5'-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy Molecular Therapy. Nucleic Acids. Jul, 2013 | Pubmed ID: 23820890 Phosphodiesterase-2 is Upregulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes Journal of the American College of Cardiology. Jun, 2013 | Pubmed ID: 23810893 Rescue of Cardiomyopathy Through U7snRNA-mediated Exon Skipping in Mybpc3-targeted Knock-in Mice EMBO Molecular Medicine. Jul, 2013 | Pubmed ID: 23716398 Development of a Colorimetric and a Fluorescence Phosphatase-inhibitor Assay Suitable for Drug Discovery Approaches Journal of Biomolecular Screening. Sep, 2013 | Pubmed ID: 23606651 Heterozygous LmnadelK32 Mice Develop Dilated Cardiomyopathy Through a Combined Pathomechanism of Haploinsufficiency and Peptide Toxicity Human Molecular Genetics. Aug, 2013 | Pubmed ID: 23575224 Impact of ANKRD1 Mutations Associated with Hypertrophic Cardiomyopathy on Contraction Parameters of Engineered Heart Tissue Basic Research in Cardiology. May, 2013 | Pubmed ID: 23572067 Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-mediated Calcium Signaling and Arrhythmias in the Heart Evoked by β-adrenergic Stimulation The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23564460 PDE4 in the Human Heart - Major Player or Little Helper? British Journal of Pharmacology. Jun, 2013 | Pubmed ID: 23489196 Parthenogenetic Stem Cells for Tissue-engineered Heart Repair The Journal of Clinical Investigation. Mar, 2013 | Pubmed ID: 23434590 [Personalized Therapy in Cardiology. Biomarkers, Pharmacogenetics and Therapy of Monogenic Diseases] Der Internist. Feb, 2013 | Pubmed ID: 23371262 A Frequent Gene Polymorphism Affecting the Heart-rate Response to Carvedilol Pharmacogenomics. Jan, 2013 | Pubmed ID: 23327570 New Tissue for Failing Hearts European Journal of Heart Failure. Jan, 2013 | Pubmed ID: 23243121 Pharmacological Characterization of 1-nitrosocyclohexyl Acetate, a Long-acting Nitroxyl Donor That Shows Vasorelaxant and Antiaggregatory Effects The Journal of Pharmacology and Experimental Therapeutics. Feb, 2013 | Pubmed ID: 23211362 A Novel Genetic Variant in the Transcription Factor Islet-1 Exerts Gain of Function on Myocyte Enhancer Factor 2C Promoter Activity European Journal of Heart Failure. Mar, 2013 | Pubmed ID: 23152444 Increased Afterload Induces Pathological Cardiac Hypertrophy: a New in Vitro Model Basic Research in Cardiology. Nov, 2012 | Pubmed ID: 23099820 The German Centre for Cardiovascular Research European Heart Journal. May, 2012 | Pubmed ID: 22893891 Progesterone Receptor Variants Associated with the PROGINS Haplotype Exhibit Functional Properties Similar to Those of Wild-type Progesterone Receptor Pharmacogenetics and Genomics. Aug, 2012 | Pubmed ID: 22722322 Increased Myocardial SERCA Expression in Early Type 2 Diabetes Mellitus is Insulin Dependent: In Vivo and in Vitro Data Cardiovascular Diabetology. May, 2012 | Pubmed ID: 22621761 Physiological Aspects of Cardiac Tissue Engineering American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2012 | Pubmed ID: 22582087 Complex Interactions Between Human Myoblasts and the Surrounding 3D Fibrin-based Matrix PloS One. 2012 | Pubmed ID: 22558372 Evidence for FHL1 As a Novel Disease Gene for Isolated Hypertrophic Cardiomyopathy Human Molecular Genetics. Jul, 2012 | Pubmed ID: 22523091 Increased Myofilament Ca2+ Sensitivity and Diastolic Dysfunction As Early Consequences of Mybpc3 Mutation in Heterozygous Knock-in Mice Journal of Molecular and Cellular Cardiology. Jun, 2012 | Pubmed ID: 22465693 Localization of Islet-1-positive Cells in the Healthy and Infarcted Adult Murine Heart Circulation Research. Mar, 2012 | Pubmed ID: 22427341 결함이 있는 단백질 시스템 Mybpc3을 대상 한 쥐 심장 비 대와 함께 Basic Research in Cardiology. Jan, 2012 | Pubmed ID: 22189562 아드레날린 스트레스 Septal 비 대 및 프로테아좀 장애를 Heterozygous Mybpc3 대상으로 노크에 쥐에서 보여준다 Journal of Muscle Research and Cell Motility. Nov, 2011 | Pubmed ID: 22076249 기초 연구 및 전 임상 독극물에 다재 다능 한 도구로 인간의 조작된 심장 조직 PloS One. 2011 | Pubmed ID: 22028871 터미널 차별화, 고급 Organotypic 성숙 및 모델링 설계 심장 조직 Hypertrophic 성장의 Circulation Research. Oct, 2011 | Pubmed ID: 21921264 비트는 계속 된다: Pluripotent 줄기 세포에서 인간의 심장 근육 Circulation Research. Jun, 2011 | Pubmed ID: 21700948 만성 수축 기 심부에 Follistatin 같은 1: 왼쪽 심 실 리 모델링의 표식 Circulation. Heart Failure. Sep, 2011 | Pubmed ID: 21622850 중간 엽 줄기 세포 조작 뼈 같은 조직의 기계적 특성에 Osteoblastic 차별화의 효과 Tissue Engineering. Part A. Sep, 2011 | Pubmed ID: 21548844 심장 마비 노인 환자의 Carvedilol 대 Bisoprolol의 대상 복용량 적정: CIBIS ELD 재판 European Journal of Heart Failure. Jun, 2011 | Pubmed ID: 21429992 인산 가수분해 효소-1 억제제-생리 적 및 병 적인 β-adrenoceptor 신호에 1 Cardiovascular Research. Aug, 2011 | Pubmed ID: 21354993 암 치료의 심혈 관계 부작용: 유럽 심장 학회 심부 협회에서 정책 위치 European Journal of Heart Failure. Jan, 2011 | Pubmed ID: 21169385 공학 Bioartificial Tracheal 조직에 콜라겐 Hydrogels 하이브리드 Fibroblast 중간 엽 줄기 세포 배양을 사용 하 여 Interactive Cardiovascular and Thoracic Surgery. Feb, 2011 | Pubmed ID: 21098511 다른 Murine 긴장의 마음에 작은 섬 1 양성 세포의 두 인구 구분 Stem Cells and Development. Jun, 2011 | Pubmed ID: 20942609 리 모델링 Hypertrophic 고 위축 하 게 심장에 일반적인 MicroRNA 서명을 Hemodynamic 부하의 변화에 의해 유도 PloS One. 2010 | Pubmed ID: 21151612 MicroRNA 199b 홍보 Calcineurin/NFAT 신호 자동 증폭 루프에 핵 니 Dyrk1a를 대상 Nature Cell Biology. Dec, 2010 | Pubmed ID: 21102440 싸움이 나 비행 응답 및 심장 마비를 Ryanodine 수용 체 인 산화 키 인가? The Journal of Clinical Investigation. Dec, 2010 | Pubmed ID: 21099119 새로운 HNO 기증자, 1 Nitrosocyclohexyl 초 산 정상과 β-adrenergically Desensitized 심 실 Myocytes에서 수축 힘 증가 Biochemical and Biophysical Research Communications. Nov, 2010 | Pubmed ID: 20946877 Myomasp/LRRC39, 심장 및 근육 관련 단백질 Sarcomeric M 밴드의 소설 구성 요소 이며 스트레치 감지에 관여 Circulation Research. Nov, 2010 | Pubmed ID: 20847312 인산 가수분해 효소-1-억제제-1: 앰프 또는 Catecholaminergic 스트레스의 감쇄 기? Basic Research in Cardiology. Sep, 2010 | Pubmed ID: 20526608 개발 플랫폼 기반으로 차단 하는 약물의 심장 조직의 설계 Circulation Research. Jul, 2010 | Pubmed ID: 20448218 [Vernakalant: 부 비 동 리듬 Atrial 세 동의 급속 한 전환에 대 한 소설 Antiarrhythmic 약] Deutsche Medizinische Wochenschrift (1946). May, 2010 | Pubmed ID: 20446233 Myeloperoxidase의 심 방 세 동 Profibrotic 중재자 역할을 합니다 Nature Medicine. Apr, 2010 | Pubmed ID: 20305660 Constitutively 활성 인산 가수분해 효소 억제 물-1 향상 젊은 쥐에 있는 심장 수축 하지만 Catecholaminergic 스트레스 및 노화와 해로운 The Journal of Clinical Investigation. Feb, 2010 | Pubmed ID: 20071777 Atrogin 1, MuRF1 다른 메커니즘을 통해 심장 MyBP C 수치를 조절 합니다 Cardiovascular Research. Jan, 2010 | Pubmed ID: 19850579 유비퀴틴-프로테아좀 시스템 및 Hypertrophic 심장 근육 병 증의 말도 중재 MRNA 감퇴 Cardiovascular Research. Jan, 2010 | Pubmed ID: 19617224 Hepatocyte 성장 인자 또는 혈관 내 피 성장 인자 유전자 이동 급성 심근 경색 후 중간 엽 줄기 세포 기반 심근 구조를 극대화합니다 Circulation. Sep, 2009 | Pubmed ID: 19752375 말도 중재 MRNA 감퇴와 유비퀴틴-프로테아좀 시스템 Cardiomyopathic 쥐에서 심장 Myosin 바인딩 단백질 C 돌연변이 수치를 조절 Circulation Research. Jul, 2009 | Pubmed ID: 19590044 인간의 Calmodulin III 유전자 프로모터에 새로운 다형성은 가족 Hypertrophic 심장 근육 병 증에 대 한 잠재적인 한정자 유전자 European Heart Journal. Jul, 2009 | Pubmed ID: 19429631 잠재적인 약물 표적으로 Adenylyl Cyclases 캡처 Nature Reviews. Drug Discovery. Apr, 2009 | Pubmed ID: 19337273 Atorvastatin 치료는 부분적으로 해로운 카 테 콜 아민 효과에서 쥐 심장을 보호 한다 Cardiovascular Research. Apr, 2009 | Pubmed ID: 19136528 Beta-adrenergic 자극 및 실패 심장에서 심근 기능 Heart Failure Reviews. Dec, 2009 | Pubmed ID: 19110970 [Not Available] MMW Fortschritte Der Medizin. Oct, 2008 | Pubmed ID: 27372484 쥐 심장의 기계적 역 단백질 키 니 아 제-인산 가수분해 효소 균형에 표시 된 변경 내용을 포함 한다 Journal of Molecular and Cellular Cardiology. Dec, 2008 | Pubmed ID: 18848565 인간의 말기 심부에서 Hypoxia을 유도할 수 있는 인자 (HIF) 통로의 부정적인 레 귤 레이 터의 활성화 Biochemical and Biophysical Research Communications. Nov, 2008 | Pubmed ID: 18782560 언로드된 쥐 마음 in Vivo 심장 Repolarization의 Hypertrophic Phenotype 익스프레스 Journal of Molecular and Cellular Cardiology. Nov, 2008 | Pubmed ID: 18721926 인산 가수분해 효소 억제 물 1 불충분 한 쥐 카 테 콜 아민 유도 부정맥 및 심근 비 대에서 보호 됩니다 Cardiovascular Research. Dec, 2008 | Pubmed ID: 18689792 심장 마비 노인 환자의 Carvedilol 대 Bisoprolol: 근거 및 CIBIS ELD 재판의 디자인 Clinical Research in Cardiology : Official Journal of the German Cardiac Society. Sep, 2008 | Pubmed ID: 18542839 Angiotensin II과 Myosin 빛 연쇄 인 산화 인간의 심 심근에 스트레치 유도 느린 힘 응답에 기여 Cardiovascular Research. Sep, 2008 | Pubmed ID: 18503051 인간의 심장에서 심 방 및 심 실 심근에 기지개를 느린 강제 응답: 기능적 관련성 및 Subcellular 메커니즘 Progress in Biophysics and Molecular Biology. Jun-Jul, 2008 | Pubmed ID: 18466959 심장에서 Beta-adrenergic 신호 실패 적응 또는 다이 Nature Medicine. May, 2008 | Pubmed ID: 18463653 인간의 심장 마비에 ATP 바인딩 카세트 운반 Naunyn-Schmiedeberg's Archives of Pharmacology. May, 2008 | Pubmed ID: 18392808 알데하이드 효소 타입-2의 억제 인간의 혈관에 니트로 글 리세 린의 Vasodilatory 작업을 약화 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2008 | Pubmed ID: 18272654 갑 상선 호르몬 조절 Phosphatidylinositol 3 키를 통해 발달 Titin Isoform 전환 / AKT 경로 Circulation Research. Feb, 2008 | Pubmed ID: 18096819 관류 및 건강 하 고 Infarcted Wistar 쥐에 기능을 평가 하기 위한 실시간 심근 콘트라스트 심장 초음파 검사 Ultrasound in Medicine & Biology. Jan, 2008 | Pubmed ID: 17854980 심장 조직 공학: 임상 관점 Future Cardiology. Jul, 2007 | Pubmed ID: 21526914 장기 Beta-adrenergic 자극 단백질 인산 가수분해 효소 억제 물-1 심장의 Downregulation으로 이어집니다 European Journal of Heart Failure. Nov, 2007 | Pubmed ID: 17921049 생물 학적 심 실 개발 지원 장치: 작은 동물 모델에서 예비 데이터 Circulation. Sep, 2007 | Pubmed ID: 17846298 심장 Myosin 바인딩 단백질 C는 그대로 Myocytes에서 완전 한 휴식을 위해 필요 합니다 Circulation Research. Oct, 2007 | Pubmed ID: 17823372 Pkcalpha을 대상으로 아 데 노 바이러스 전달 짧은 헤어핀 RNA 재구성된 심장 조직에 수축 성 기능을 향상 시킵니다 Journal of Molecular and Cellular Cardiology. Sep, 2007 | Pubmed ID: 17628588 인간적이 고 실험적인 심장 마비에 심장 Myosin 바인딩 단백질 C 수준의 감소 인 산화 Journal of Molecular and Cellular Cardiology. Aug, 2007 | Pubmed ID: 17560599 임상 장비를 사용 하 여 작은 동물 Transthoracic 초음파의 재현성 Coronary Artery Disease. Jun, 2007 | Pubmed ID: 17496492 심장 근육 엔지니어링에 대 한 배아 줄기 세포입니다 Trends in Cardiovascular Medicine. May, 2007 | Pubmed ID: 17482096 뉴 클레 오 시드 Diphosphate 니 B/G 단백질 베타 감마 Dimer 복합물에 의해 수축 및 심장 캠프 합성의 규제 Circulation Research. Apr, 2007 | Pubmed ID: 17363702 만성 심장 Calmodulin 키 니 아 제 2 차 억제 된 마우스에서 Atria Alpha1 아드레날린 자극 수축 반응 감소 Journal of Molecular and Cellular Cardiology. Mar, 2007 | Pubmed ID: 17292391 2988G >는 다형성 CYP2D6 Minigene의 접합에 영향을 줍니다 Clinical Pharmacology and Therapeutics. Nov, 2006 | Pubmed ID: 17112815 소아 급성 림프 구성 백혈병에서 높은 복용량 Methotrexate: ABCC2 Polymorphisms 플라즈마 농도에 미치는 영향 Clinical Pharmacology and Therapeutics. Nov, 2006 | Pubmed ID: 17112803 분자 결정의 변경 된 Ca2 + 인간의 만성 심 방 세 동에 처리 Circulation. Aug, 2006 | Pubmed ID: 16894034 대리 심장 근육으로 심장 조직을 치료 응용 프로그램에 대 한 설계를 최적화 Circulation. Jul, 2006 | Pubmed ID: 16820649 MLCK 중재 Alpha1 아드레날린 Inotropic 효과 심 심근에는 부정적인 PKCepsilon 신호 변조 British Journal of Pharmacology. Aug, 2006 | Pubmed ID: 16783412 역할 Calcineurin 및 단백질 인산 가수분해 효소 2A 심장 Myocytes에서 인산 가수분해 효소 억제 물-1의 규정에의 합니다 Biochemical and Biophysical Research Communications. Aug, 2006 | Pubmed ID: 16774736 심장 근육 공학: 심장 근육 대체 요법에 대 한 업데이트 Cardiovascular Research. Aug, 2006 | Pubmed ID: 16697358 조작된 심장 조직 이식 Infarcted 쥐 마음에 심장 수축과 심장 확장 기능을 향상 Nature Medicine. Apr, 2006 | Pubmed ID: 16582915 심장에 심장 Myocyte 셀 시트의 전기 커플링 Circulation Research. Mar, 2006 | Pubmed ID: 16543504 Atorvastatin Desensitizes Beta-adrenergic G-단백질 감마 Subunits의 감소 Isoprenylation 통해 심장 Myocytes에서 신호 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2006 | Pubmed ID: 16467371 심장 비 대에 Preproenkephalin 시스템과 Atrioventricular 전도 역할 변경 Cardiovascular Research. Feb, 2006 | Pubmed ID: 16376326 엔지니어링 심근 조직입니다 Circulation Research. Dec, 2005 | Pubmed ID: 16339494 심장 재생에 심장 조상 세포 순환의 관련성을 의심 Cardiovascular Research. Dec, 2005 | Pubmed ID: 16253213 Endothelin 1과 Isoprenaline Co-stimulation MEK 저해 반대로 부분적으로 수축 실패를 발생 합니다 Cardiovascular Research. Dec, 2005 | Pubmed ID: 16040022 성인 Cardiomyocytes에 두 5-HT4 수용 체 Isoforms의 차동 기능 효과 Journal of Molecular and Cellular Cardiology. Aug, 2005 | Pubmed ID: 15950987 잘린된 심장 Myosin 바인딩 단백질 C 돌연변이 의해 유비퀴틴-프로테아좀 시스템의 장애 Cardiovascular Research. Apr, 2005 | Pubmed ID: 15769446 Myosin 빛 체인 (MLC) 니 중재 MLC2a 인 산화 인간 아 트리 움의 알파 1 아드레날린 양수 Inotropic 효과에서 중요 한 역할 Cardiovascular Research. Jan, 2005 | Pubmed ID: 15621049 [심장 부족에 베타 차단제입니다. 언제, 얼마나 및 물질] Medizinische Monatsschrift Für Pharmazeuten. Dec, 2004 | Pubmed ID: 15646690 메의 플라스마 수준에 Amiodarone의 영향 The American Journal of Cardiology. Nov, 2004 | Pubmed ID: 15541258 CYP2D6 유전자 형: 불리 한 효과 항우울제는 파일럿 연구와 치료 하는 동안 Nonresponse에 미치는 영향 Clinical Pharmacology and Therapeutics. May, 2004 | Pubmed ID: 15116051 Ouabain 치료는 연관 된 인산 가수분해 효소 억제 물-1 나의 Upregulation + Ca(2+) 교환기 및 Beta-adrenergic 민감성 쥐 마음에 Biochemical and Biophysical Research Communications. May, 2004 | Pubmed ID: 15110776 S100A1 유전자 이동: 강화 전략 설계 심장 이식 The Journal of Gene Medicine. Apr, 2004 | Pubmed ID: 15079813 Myocyte 심장 수축 기능에 만성 Endothelin 1 자극의 효과 American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2004 | Pubmed ID: 15020300 수용 N-메 틸-D-aspartate 수용 체 소 단위 NR2B 및 Ryanodine 체 2 신생아 쥐 Myocard에 의해 분자 단지의 형성 The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 15010472 인간의 Homozygous R403W 돌연변이 심장 Myosin 기계와 Enzymatic 속성의 균형이 향상을 제공합니다 Journal of Molecular and Cellular Cardiology. Mar, 2004 | Pubmed ID: 15010274 단백질 인산 가수분해 효소 억제 물-1 실패 하는 인간의 마음에서의 감소 단백질 및 인 산화 수준 Cardiovascular Research. Jan, 2004 | Pubmed ID: 14732205 심장 조직을 병에 걸린 마음 재생을 위해 설계 되었습니다 Biomaterials. Apr, 2004 | Pubmed ID: 14697865 노르 Upregulates 혈관 내 피 성장 인자 Paracrine 메커니즘에 의해 쥐 심장 Myocytes에서 Angiogenesis. 2003 | Pubmed ID: 15166499 금지 G-단백질 및 심장 마비에 있는 Adenylyl Cyclase 통로의 둔감도에 그들의 역할 Cardiovascular Research. Dec, 2003 | Pubmed ID: 14659793 대동맥 심장 밸브의 조직 공학입니다 Cardiovascular Research. Dec, 2003 | Pubmed ID: 14659789 Beta-adrenergic 신호 심장 마비에서의 역할은 무엇 인가? Circulation Research. Nov, 2003 | Pubmed ID: 14615493 인간의 Myocardium 실패에 기/이동-단백질 M Cholinoceptors의 차동 결합 Journal of Molecular and Cellular Cardiology. Oct, 2003 | Pubmed ID: 14519434 Heme Oxygenase-1 및 반응 제품, 일산화 탄소, 생쥐에서 염증 관련 Apoptotic 간 손상을 방지합니다 Hepatology (Baltimore, Md.). Oct, 2003 | Pubmed ID: 14512878 Beta-adrenergic 자극 유도 심장 Ankyrin 반복 단백질 식: 단백질 키 니 아 제 A 및 Calmodulin 종속 키의 참여 Cardiovascular Research. Sep, 2003 | Pubmed ID: 14499857 대체 요법에 대 한 심장 조직 공학입니다 Heart Failure Reviews. Jul, 2003 | Pubmed ID: 12878835 야생-타입 Galpha (i)-2 Overexpression 심장 Myocytes에서 Beta-adrenergic 신호를 표시 하지 않습니다 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003 | Pubmed ID: 12631586 단백질 인산 가수분해 효소 억제 물-1에 심장 Myocytes에서 Beta-adrenergic 신호 증폭기 역할에 대 한 증거 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003 | Pubmed ID: 12514122 3 차원 심장 조직을 대체 요법에 대 한 설계 Basic Research in Cardiology. 2002 | Pubmed ID: 12479248 시 토 크롬 P450의 주파수를 증가 2D 6 메 관련 부작용 환자 가운데 불 쌍 한 Metabolizers Clinical Pharmacology and Therapeutics. Oct, 2002 | Pubmed ID: 12386645 심장의 접목 Syngenic 쥐에서 심장 조직의 설계 Circulation. Sep, 2002 | Pubmed ID: 12354725 실패 하는 인간의 마음에 Cardiotrophin 1 증강된 표현의 저하 당단백질 130 수용 체 단백질 풍부한 함께 제공 됩니다 Circulation. Sep, 2002 | Pubmed ID: 12234945 심장 조직 공학입니다 Transplant Immunology. May, 2002 | Pubmed ID: 12180846 인간의 심근에 10 RGS 단백질의 표현: 심장 마비에 Rgs4의 Upregulation의 기능적 특성 Cardiovascular Research. Sep, 2002 | Pubmed ID: 12176127 메 신진 대사에 영향 CYP2D6 유전자 형의 장기 치료 하는 동안 유지 됩니다 Pharmacogenetics. Aug, 2002 | Pubmed ID: 12172215 세포내 베타 봉쇄: Galpha(i2)의 Overexpression Depresses 그대로 심근에서 Beta-adrenergic 응답 합니다 Cardiovascular Research. Aug, 2002 | Pubmed ID: 12123769 심장 Ankyrin 반복 단백질, 심장 유전자 발현의 부정적인 레 귤 레이 터는 인간의 심장 마비에 증강 됩니다 Biochemical and Biophysical Research Communications. May, 2002 | Pubmed ID: 12054667 특정 베타 (2) AR 차단기 시오 118,551 적극적으로 통해 G (i) 수축 감소-베타 (2)의 형태로 결합 하 여 실패 하는 인간의 마음에서 Myocytes에서 AR Circulation. May, 2002 | Pubmed ID: 12034656 심 실 베타 1-adrenoceptors와 알파 1-adrenoceptors 하지만 아무 베타 2-에 대 한 증거와 Murine 마음에 베타 3 Adrenoceptor 기능 사이의 생리 적인 적개심 British Journal of Pharmacology. May, 2002 | Pubmed ID: 12010770 Renovascular 고혈압 쥐에서 Tranilast에 의해 왼쪽된 심 실 섬유 증의 억제 Journal of Hypertension. Apr, 2002 | Pubmed ID: 11910312 왼쪽 심 실 심장 Endothelin 시스템의 활성화 27 쥐 TG (mREN2)에서 심장 마비의 발병 하기 전에 비 대 Cardiovascular Research. Feb, 2002 | Pubmed ID: 11827687 엔지니어링 심장 조직에서 후부하의 자기 조정 Benjamin Becker*1,2, Marita L. Rodriguez*1,2, Tessa R. Werner1,2, Justus Stenzig1,2, Thomas Eschenhagen1,2, Marc N. Hirt1,2 1Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 2DZHK (German Centre for Cardiovascular Research) JoVE 60811 Developmental Biology 기니 돼지 모델에서 심근 손상 후 심장 근육 패치 hiPSC 파생의 이식 Liesa Castro1,2, Birgit Geertz3, Marina Reinsch2,3, Bülent Aksehirlioglu3, Arne Hansen2,3, Thomas Eschenhagen2,3, Hermann Reichenspurner1,2, Florian Weinberger*2,3, Simon Pecha*1,2 1Department of Cardiovascular Surgery, University Heart Center Hamburg, 2partner site Hamburg/Kiel/Lübeck, German Centre for Cardiovascular Research (DZHK), 3Department of Experimental Pharmacology and Toxicology, Cardiovascular ResearchCenter, University Medical Center Hamburg-Eppendorf JoVE 58810 Medicine 심장 약물 안전 검사를위한 인간 공학 심장 조직의 자동 수축 분석 Ingra Mannhardt1, Umber Saleem1, Anika Benzin1, Thomas Schulze1, Birgit Klampe1, Thomas Eschenhagen1, Arne Hansen1 1Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf and DZHK (German Center for Cardiovascular Research) JoVE 55461 Bioengineering 엔지니어링된 심장 조직 이식 다음과 같은 면역 반응의 평가 (EHT)에 대한 Bioluminescence 이미징 Lenard Conradi1,2, Christiane Pahrmann1, Stephanie Schmidt1, Tobias Deuse1,3, Arne Hansen2, Alexandra Eder2, Hermann Reichenspurner1, Robert C. Robbins3, Thomas Eschenhagen2, Sonja Schrepfer1,3 1Transplant and Stem Cell Immunobiology Lab (TSI) and CVRC, University Hospital Hamburg, University Heart Center Hamburg, 2Department of Experimental and Clinical Pharmacology and Toxicology, University Heart Center Hamburg, 3CT Surgery, Stanford University School of Medicine JoVE 2605 Bioengineering
엔지니어링 심장 조직에서 후부하의 자기 조정 Benjamin Becker*1,2, Marita L. Rodriguez*1,2, Tessa R. Werner1,2, Justus Stenzig1,2, Thomas Eschenhagen1,2, Marc N. Hirt1,2 1Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 2DZHK (German Centre for Cardiovascular Research) JoVE 60811 Developmental Biology
기니 돼지 모델에서 심근 손상 후 심장 근육 패치 hiPSC 파생의 이식 Liesa Castro1,2, Birgit Geertz3, Marina Reinsch2,3, Bülent Aksehirlioglu3, Arne Hansen2,3, Thomas Eschenhagen2,3, Hermann Reichenspurner1,2, Florian Weinberger*2,3, Simon Pecha*1,2 1Department of Cardiovascular Surgery, University Heart Center Hamburg, 2partner site Hamburg/Kiel/Lübeck, German Centre for Cardiovascular Research (DZHK), 3Department of Experimental Pharmacology and Toxicology, Cardiovascular ResearchCenter, University Medical Center Hamburg-Eppendorf JoVE 58810 Medicine
심장 약물 안전 검사를위한 인간 공학 심장 조직의 자동 수축 분석 Ingra Mannhardt1, Umber Saleem1, Anika Benzin1, Thomas Schulze1, Birgit Klampe1, Thomas Eschenhagen1, Arne Hansen1 1Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf and DZHK (German Center for Cardiovascular Research) JoVE 55461 Bioengineering
엔지니어링된 심장 조직 이식 다음과 같은 면역 반응의 평가 (EHT)에 대한 Bioluminescence 이미징 Lenard Conradi1,2, Christiane Pahrmann1, Stephanie Schmidt1, Tobias Deuse1,3, Arne Hansen2, Alexandra Eder2, Hermann Reichenspurner1, Robert C. Robbins3, Thomas Eschenhagen2, Sonja Schrepfer1,3 1Transplant and Stem Cell Immunobiology Lab (TSI) and CVRC, University Hospital Hamburg, University Heart Center Hamburg, 2Department of Experimental and Clinical Pharmacology and Toxicology, University Heart Center Hamburg, 3CT Surgery, Stanford University School of Medicine JoVE 2605 Bioengineering