Timothy R. DeGrado Department of Radiology University of Colorado Anschutz Medical Campus Biography Publications Institution JoVE Articles Timothy R. DeGrado has not added a biography. If you are Timothy R. DeGrado and would like to personalize this page please email our Author Liaison for assistance. Publications Design, Synthesis, and Preliminary Evaluation of [Ga]Ga-NOTA-Insulin As a PET Probe in an Alzheimer's Disease Mouse Model Bioconjugate Chemistry. May, 2022 | Pubmed ID: 35420782 A New Solid Target Design for the Production of Zr and Radiosynthesis of High Molar Activity [Zr]Zr-DBN American Journal of Nuclear Medicine and Molecular Imaging. 2022 | Pubmed ID: 35295887 Development of a Clinically Relevant Reporter for Chimeric Antigen Receptor T-cell Expansion, Trafficking, and Toxicity Cancer Immunology Research. 09, 2021 | Pubmed ID: 34244299 Non-invasive ImmunoPET Imaging of PD-L1 Using Anti-PD-L1-B11 in Breast Cancer and Melanoma Tumor Model Nuclear Medicine and Biology. Sep-Oct, 2021 | Pubmed ID: 34119742 Evaluation of Zn, Cu, and Se Levels in the North American Autism Spectrum Disorder Population Frontiers in Molecular Neuroscience. 2021 | Pubmed ID: 33994944 Cyclotron Production of PET Radiometals in Liquid Targets: Aspects and Prospects Current Radiopharmaceuticals. 2021 | Pubmed ID: 32867656 [Zr]Zr-DBN Labeled Cardiopoietic Stem Cells Proficient for Heart Failure Nuclear Medicine and Biology. Nov - Dec, 2020 | Pubmed ID: 32957056 Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure Molecular Therapy. Methods & Clinical Development. Sep, 2020 | Pubmed ID: 32913881 Catechol-Based Functionalizable Ligands for Gallium-68 Positron Emission Tomography Imaging Inorganic Chemistry. Sep, 2020 | Pubmed ID: 32820888 Radiation Induced Oxidation of [F]fluorothia Fatty Acids Under CGMP Manufacturing Conditions Nuclear Medicine and Biology. Jan - Feb, 2020 | Pubmed ID: 31759313 Enhanced Noninvasive Imaging of Oncology Models Using the NIS Reporter Gene and Bioluminescence Imaging Cancer Gene Therapy. 04, 2020 | Pubmed ID: 30674994 Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection Molecular Therapy Oncolytics. Dec, 2019 | Pubmed ID: 31890867 Cyclotron Production of Ga in a Liquid Target: Effects of Solution Composition and Irradiation Parameters Nuclear Medicine and Biology. Jul - Aug, 2019 | Pubmed ID: 31085059 Cloning, Function, and Localization of Human, Canine, and Drosophila ZIP10 (SLC39A10), a Zn Transporter American Journal of Physiology. Renal Physiology. 02, 2019 | Pubmed ID: 30520657 Noninvasive Evaluation of Fat-carbohydrate Metabolic Switching in Heart and Contracting Skeletal Muscle American Journal of Physiology. Endocrinology and Metabolism. 02, 2019 | Pubmed ID: 30512988 New Transgenic NIS Reporter Rats for Longitudinal Tracking of Fibrogenesis by High-resolution Imaging Scientific Reports. 09, 2018 | Pubmed ID: 30242176 [F]Tetrafluoroborate ([F]TFB) and Its Analogs for PET Imaging of the Sodium/iodide Symporter Theranostics. 2018 | Pubmed ID: 30083270 Hepatocyte Spheroids As an Alternative to Single Cells for Transplantation After Ex Vivo Gene Therapy in Mice and Pig Models Surgery. Sep, 2018 | Pubmed ID: 29884476 Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2 Biochemistry. 07, 2018 | Pubmed ID: 29791142 Synthesis and Evaluation of F-hexafluorophosphate As a Novel PET Probe for Imaging of Sodium/iodide Symporter in a Murine C6-glioma Tumor Model Bioorganic & Medicinal Chemistry. 01, 2018 | Pubmed ID: 29198608 Safety, Pharmacokinetics, Metabolism and Radiation Dosimetry of F-tetrafluoroborate (F-TFB) in Healthy Human Subjects EJNMMI Research. Oct, 2017 | Pubmed ID: 29080017 First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease Molecular Imaging. 2016 | Pubmed ID: 27941122 Curative Ex Vivo Liver-directed Gene Therapy in a Pig Model of Hereditary Tyrosinemia Type 1 Science Translational Medicine. Jul, 2016 | Pubmed ID: 27464750 Synthesis of 18F-Tetrafluoroborate Via Radiofluorination of Boron Trifluoride and Evaluation in a Murine C6-Glioma Tumor Model Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Sep, 2016 | Pubmed ID: 27103021 Glycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and Imaging Theranostics. 2016 | Pubmed ID: 26941849 Imaging of Myocardial Fatty Acid Oxidation Biochimica Et Biophysica Acta. 10, 2016 | Pubmed ID: 26923433 Tracking and Therapeutic Value of Human Adipose Tissue-derived Mesenchymal Stem Cell Transplantation in Reducing Venous Neointimal Hyperplasia Associated with Arteriovenous Fistula Radiology. May, 2016 | Pubmed ID: 26583911 Improved Production and Processing of ⁸⁹Zr Using a Solution Target Nuclear Medicine and Biology. Jan, 2016 | Pubmed ID: 26471714 Production and Transport of Gaseous F-Synthons: F-Acyl Fluorides Journal of Fluorine Chemistry. Dec, 2015 | Pubmed ID: 27003949 Novel (89)Zr Cell Labeling Approach for PET-based Cell Trafficking Studies EJNMMI Research. 2015 | Pubmed ID: 25918673 Measles Edmonston Vaccine Strain Derivatives Have Potent Oncolytic Activity Against Osteosarcoma Cancer Gene Therapy. Nov, 2014 | Pubmed ID: 25394505 Preparation and Preliminary Evaluation of 63Zn-zinc Citrate As a Novel PET Imaging Biomarker for Zinc Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2014 | Pubmed ID: 25047329 Synthesis and Preliminary Evaluation of N-(16-18F-fluorohexadecanoyl)ethanolamine (18F-FHEA) As a PET Probe of N-acylethanolamine Metabolism in Mouse Brain ACS Chemical Neuroscience. Sep, 2014 | Pubmed ID: 25003845 Cyclotron Production of (68)Ga Via the (68)Zn(p,n)(68)Ga Reaction in Aqueous Solution American Journal of Nuclear Medicine and Molecular Imaging. 2014 | Pubmed ID: 24982816 Production of 89Zr Via the 89Y(p,n)89Zr Reaction in Aqueous Solution: Effect of Solution Composition on In-target Chemistry Nuclear Medicine and Biology. Apr, 2014 | Pubmed ID: 24607433 Structure Dependence of Long-chain [18F]fluorothia Fatty Acids As Myocardial Fatty Acid Oxidation Probes Journal of Medicinal Chemistry. Dec, 2012 | Pubmed ID: 23153307 Positron Emission Tomography Imaging of Cell Trafficking: A Method of Cell Radiolabeling Aditya Bansal1, Timothy R. DeGrado2, Mukesh K. Pandey1 1Division of Nuclear Medicine, Department of Radiology, Mayo Clinic, 2Department of Radiology, University of Colorado Anschutz Medical Campus JoVE 64117 Cancer Research Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography Reona Sakemura1,2, Michelle J. Cox1,2, Aditya Bansal3, Claudia Manriquez Roman1,2,4,5, Mehrdad Hefazi1,2, Cynthia J. Vernon3, Dianna L. Glynn3, Mukesh K. Pandey3, Timothy R. DeGrado3, Elizabeth L. Siegler1,2, Saad S. Kenderian1,2,5,6 1T Cell Engineering, Mayo Clinic, 2Division of Hematology, Mayo Clinic, 3Department of Radiology, Mayo Clinic, 4Regenerative Sciences PhD, Mayo Clinic, 5Department of Molecular Medicine, Mayo Clinic, 6Department of Immunology, Mayo Clinic JoVE 62334 Cancer Research
Positron Emission Tomography Imaging of Cell Trafficking: A Method of Cell Radiolabeling Aditya Bansal1, Timothy R. DeGrado2, Mukesh K. Pandey1 1Division of Nuclear Medicine, Department of Radiology, Mayo Clinic, 2Department of Radiology, University of Colorado Anschutz Medical Campus JoVE 64117 Cancer Research
Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography Reona Sakemura1,2, Michelle J. Cox1,2, Aditya Bansal3, Claudia Manriquez Roman1,2,4,5, Mehrdad Hefazi1,2, Cynthia J. Vernon3, Dianna L. Glynn3, Mukesh K. Pandey3, Timothy R. DeGrado3, Elizabeth L. Siegler1,2, Saad S. Kenderian1,2,5,6 1T Cell Engineering, Mayo Clinic, 2Division of Hematology, Mayo Clinic, 3Department of Radiology, Mayo Clinic, 4Regenerative Sciences PhD, Mayo Clinic, 5Department of Molecular Medicine, Mayo Clinic, 6Department of Immunology, Mayo Clinic JoVE 62334 Cancer Research
