Timothy O'Connor

Publications

• The Effect of the Charge-Separating Interface on Exciton Dynamics in Photocatalytic Colloidal Heteronanocrystals
  ACS Nano. Aug, 2012  |   Pubmed ID: 22881284
• Reorganization of Posterior Language Area in Temporal Lobe Epilepsy: A Cortico-cortical Evoked Potential Study
  Epilepsy Research. Jul, 2012  |   Pubmed ID: 22819071
• Transmembrane Semaphorin5B is Proteolytically Processed into a Repulsive Neural Guidance Cue
  Journal of Neurochemistry. Jul, 2012  |   Pubmed ID: 22817385
• 175 Language Reorganization in Temporal Lobe Epilepsy: A Cortico-cortical Evoked Potential Study
  Neurosurgery. Aug, 2012  |   Pubmed ID: 22811164
• Enhancement of Synthetic Lethality Via Combinations of ABT-888 (a PARP Inhibitor) and Carboplatin in Vitro and in Vivo Using BRCA1 and BRCA2 Isogenic Models
  Molecular Cancer Therapeutics. Jul, 2012  |   Pubmed ID: 22778154
• Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
  Science (New York, N.Y.). Jul, 2012  |   Pubmed ID: 22604720
• Chronic Myelogenous Leukemia Stem and Progenitor Cells Demonstrate Chromosomal Instability Related to Repeated Breakage-fusion-bridge Cycles Mediated by Increased Nonhomologous End Joining
  Blood. Jun, 2012  |   Pubmed ID: 22493298
• Correlations Between Ictal Propagation and Response to Electrical Cortical Stimulation: A Cortico-cortical Evoked Potential Study
  Epilepsy Research. Aug, 2012  |   Pubmed ID: 22459638
• Alkbh2 Protects Against Lethality and Mutation in Primary Mouse Embryonic Fibroblasts
  DNA Repair. May, 2012  |   Pubmed ID: 22429847
• DNA Repair in Human Pluripotent Stem Cells is Distinct from That in Non-pluripotent Human Cells
  PloS One. 2012  |   Pubmed ID: 22412831
• Insights into Hominid Evolution from the Gorilla Genome Sequence
  Nature. Mar, 2012  |   Pubmed ID: 22398555
• Cortical Excitability Varies Upon Ictal Onset Patterns in Neocortical Epilepsy: a Cortico-cortical Evoked Potential Study
  Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Feb, 2012  |   Pubmed ID: 21802356
• Fabrication of All-inorganic Nanocrystal Solids Through Matrix Encapsulation of Nanocrystal Arrays
  Journal of the American Chemical Society. Dec, 2011  |   Pubmed ID: 22081872
• The Promise and Limitations of Population Exomics for Human Evolution Studies
  Genome Biology. 2011  |   Pubmed ID: 21920050
• Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking
  PloS One. 2011  |   Pubmed ID: 21829517
• Cerebroprotection by Angiotensin-(1-7) in Endothelin-1-induced Ischaemic Stroke
  Experimental Physiology. Oct, 2011  |   Pubmed ID: 21685445
• The Role of Hole Localization in Sacrificial Hydrogen Production by Semiconductor-metal Heterostructured Nanocrystals
  Nano Letters. Jul, 2011  |   Pubmed ID: 21615085
• Heteroepitaxial Growth of Colloidal Nanocrystals Onto Substrate Films Via Hot-injection Routes
  ACS Nano. Jun, 2011  |   Pubmed ID: 21526765
• The Roles of DNA Polymerases κ and ι in the Error-free Bypass of N2-carboxyalkyl-2'-deoxyguanosine Lesions in Mammalian Cells
  The Journal of Biological Chemistry. May, 2011  |   Pubmed ID: 21454642
• Ephus: Multipurpose Data Acquisition Software for Neuroscience Experiments
  Frontiers in Neural Circuits. 2010  |   Pubmed ID: 21960959
• Analysis of Long Branch Extraction and Long Branch Shortening
  BMC Genomics. 2010  |   Pubmed ID: 21047381
• 6-Thioguanine and S⁶-methylthioguanine Are Mutagenic in Human Cells
  ACS Chemical Biology. Nov, 2010  |   Pubmed ID: 20806951
• Ceres: Software for the Integrated Analysis of Transcription Factor Binding Sites and Nucleosome Positions in Saccharomyces Cerevisiae
  Bioinformatics (Oxford, England). Jan, 2010  |   Pubmed ID: 19959498
• Algorithm for Writing a Scientific Manuscript
  Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. Nov, 2009  |   Pubmed ID: 21567769
• Trachea Epithelium As a "canary" for Cigarette Smoking-induced Biologic Phenotype of the Small Airway Epithelium
  Clinical and Translational Science. Aug, 2009  |   Pubmed ID: 20443905
• Emphysema Mediated by Lung Overexpression of ADAM10
  Clinical and Translational Science. Feb, 2009  |   Pubmed ID: 20443867
• Disparate Oxidant Gene Expression of Airway Epithelium Compared to Alveolar Macrophages in Smokers
  Respiratory Research. 2009  |   Pubmed ID: 19919714
• Quality Control in Microarray Assessment of Gene Expression in Human Airway Epithelium
  BMC Genomics. 2009  |   Pubmed ID: 19852842
• Myosin-Va-interacting Protein, RILPL2, Controls Cell Shape and Neuronal Morphogenesis Via Rac Signaling
  Journal of Cell Science. Oct, 2009  |   Pubmed ID: 19812310
• Smoking-dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary Disease
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009  |   Pubmed ID: 19635926
• Genotype-phenotype Associations: Substitution Models to Detect Evolutionary Associations Between Phenotypic Variables and Genotypic Evolutionary Rate
  Bioinformatics (Oxford, England). Jun, 2009  |   Pubmed ID: 19478022
• Semaphorin 5B Mediates Synapse Elimination in Hippocampal Neurons
  Neural Development. 2009  |   Pubmed ID: 19463192
• Candesartan Pretreatment is Cerebroprotective in a Rat Model of Endothelin-1-induced Middle Cerebral Artery Occlusion
  Experimental Physiology. Aug, 2009  |   Pubmed ID: 19429641
• Genetic Control of Wayward Pluripotent Stem Cells and Their Progeny After Transplantation
  Cell Stem Cell. Apr, 2009  |   Pubmed ID: 19341619
• Cigarette Smoking Induces Overexpression of a Fat-depleting Gene AZGP1 in the Human
  Chest. May, 2009  |   Pubmed ID: 19188554
• Varicones and Growth Cones: Two Neurite Terminals in PC12 Cells
  PloS One. 2009  |   Pubmed ID: 19183810
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  Epilepsia. Jun, 2009  |   Pubmed ID: 19175399
• Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease
  American Journal of Respiratory and Critical Care Medicine. Mar, 2009  |   Pubmed ID: 19106307
• Neurite Consolidation is an Active Process Requiring Constant Repression of Protrusive Activity
  The EMBO Journal. Feb, 2009  |   Pubmed ID: 19096364
• Semaphorin 5B is a Novel Inhibitory Cue for Corticofugal Axons
  Cerebral Cortex (New York, N.Y. : 1991). Jun, 2009  |   Pubmed ID: 18842660
• Parsimony Accelerated Maximum Likelihood Searches
  International Journal of Computational Biology and Drug Design. 2008  |   Pubmed ID: 20055002
• A Novel Diketopiperazine Stimulates Sprouting of Spinally Projecting Axons
  Experimental Neurology. Dec, 2008  |   Pubmed ID: 18926822
• Osiris: an Integrated Promoter Database for Oryza Sativa L
  Bioinformatics (Oxford, England). Dec, 2008  |   Pubmed ID: 18922805
• Variability in Small Airway Epithelial Gene Expression Among Normal Smokers
  Chest. Jun, 2008  |   Pubmed ID: 18339782
• Inhibiting Wild-type and C299S Mutant AKR1B10; a Homologue of Aldose Reductase Upregulated in Cancers
  European Journal of Pharmacology. Apr, 2008  |   Pubmed ID: 18325492
• A High-throughput Screen to Identify Novel Compounds to Promote Neurite Outgrowth
  Journal of Neuroscience Methods. Mar, 2008  |   Pubmed ID: 18178254
• Pharmacogenomics: Analysing SNPs in the CYP2D6 Gene Using Amino Acid Properties
  International Journal of Bioinformatics Research and Applications. 2007  |   Pubmed ID: 18048313
• Combined Activation of Calpain and Calcineurin During Ligand-induced Growth Cone Collapse
  Molecular and Cellular Neurosciences. Dec, 2007  |   Pubmed ID: 17826176
• DNA Reference Alignment Benchmarks Based on Tertiary Structure of Encoded Proteins
  Bioinformatics (Oxford, England). Oct, 2007  |   Pubmed ID: 17686799
• Nucleotide Excision Repair Eliminates Unique DNA-protein Cross-links from Mammalian Cells
  The Journal of Biological Chemistry. Aug, 2007  |   Pubmed ID: 17507378
• ChromatinDB: a Database of Genome-wide Histone Modification Patterns for Saccharomyces Cerevisiae
  Bioinformatics (Oxford, England). Jul, 2007  |   Pubmed ID: 17485428
• Monitoring Repair of DNA Damage in Cell Lines and Human Peripheral Blood Mononuclear Cells
  Analytical Biochemistry. Jun, 2007  |   Pubmed ID: 17449003
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  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007  |   Pubmed ID: 17360641
• Human Embryonic Stem Cells and Gene Therapy
  Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2007  |   Pubmed ID: 17356540
• Soy Protein and Isoflavones Influence Adiposity and Development of Metabolic Syndrome in the Obese Male ZDF Rat
  Annals of Nutrition & Metabolism. 2007  |   Pubmed ID: 17356265
• Upregulation of Pirin Expression by Chronic Cigarette Smoking is Associated with Bronchial Epithelial Cell Apoptosis
  Respiratory Research. 2007  |   Pubmed ID: 17288615
• DNA Polymerase Delta-dependent Repair of DNA Single Strand Breaks Containing 3'-end Proximal Lesions
  Nucleic Acids Research. 2007  |   Pubmed ID: 17264132
• Interaction of Pneumocystis Carinii with Dendritic Cells and Resulting Host Responses to P. Carinii
  Journal of Immunotherapy (Hagerstown, Md. : 1997). Jan, 2007  |   Pubmed ID: 17198083
• High Oxidative Damage Levels in the Longest-living Rodent, the Naked Mole-rat
  Aging Cell. Dec, 2006  |   Pubmed ID: 17054663
• Adenoviral Gene Transfer of Stromal Cell-derived Factor-1 to Murine Tumors Induces the Accumulation of Dendritic Cells and Suppresses Tumor Growth
  Cancer Research. Apr, 2006  |   Pubmed ID: 16585175
• Genetic Medicines: Treatment Strategies for Hereditary Disorders
  Nature Reviews. Genetics. Apr, 2006  |   Pubmed ID: 16543931
• Gene Expression Profiling of Human Alveolar Macrophages of Phenotypically Normal Smokers and Nonsmokers Reveals a Previously Unrecognized Subset of Genes Modulated by Cigarette Smoking
  Journal of Molecular Medicine (Berlin, Germany). Apr, 2006  |   Pubmed ID: 16520944
• Calmodulin Signaling: Analysis and Prediction of a Disorder-dependent Molecular Recognition
  Proteins. May, 2006  |   Pubmed ID: 16493654
• Development of Enzymatic Probes of Oxidative and Nitrosative DNA Damage Caused by Reactive Nitrogen Species
  Mutation Research. Feb, 2006  |   Pubmed ID: 16274707
• Characterization of the 3' --> 5' Exonuclease Activity Found in Human Nucleoside Diphosphate Kinase 1 (NDK1) and Several of Its Homologues
  Biochemistry. Dec, 2005  |   Pubmed ID: 16313181
• Athena: a Resource for Rapid Visualization and Systematic Analysis of Arabidopsis Promoter Sequences
  Bioinformatics (Oxford, England). Dec, 2005  |   Pubmed ID: 16223790
• Repair of Methylation Damage in DNA and RNA by Mammalian AlkB Homologues
  The Journal of Biological Chemistry. Nov, 2005  |   Pubmed ID: 16174769
• Gene Transfer of the Vascular Endothelial Growth Factor Receptor Flt-1 Suppresses Pulmonary Metastasis Associated with Lung Growth
  American Journal of Respiratory Cell and Molecular Biology. Dec, 2005  |   Pubmed ID: 16151052
• Antioxidants Do Not Explain the Disparate Longevity Between Mice and the Longest-living Rodent, the Naked Mole-rat
  Mechanisms of Ageing and Development. Nov, 2005  |   Pubmed ID: 16087218
• Similarity of Gene Expression Patterns in Human Alveolar Macrophages in Response to Pseudomonas Aeruginosa and Burkholderia Cepacia
  Infection and Immunity. Aug, 2005  |   Pubmed ID: 16041053
• XRCC1 Interactions with Multiple DNA Glycosylases: a Model for Its Recruitment to Base Excision Repair
  DNA Repair. Jul, 2005  |   Pubmed ID: 15927541
• Repair of Cyclobutane Pyrimidine Dimers or Dimethylsulfate Damage in DNA is Identical in Normal or Telomerase-immortalized Human Skin Fibroblasts
  Nucleic Acids Research. 2005  |   Pubmed ID: 15863724
• Effect of Dietary Fatty Acid Composition on Depot Fat and Exercise Performance in a Migrating Songbird, the Red-eyed Vireo
  The Journal of Experimental Biology. Apr, 2005  |   Pubmed ID: 15781888
• Human 3-methyladenine-DNA Glycosylase: Effect of Sequence Context on Excision, Association with PCNA, and Stimulation by AP Endonuclease
  Journal of Molecular Biology. Mar, 2005  |   Pubmed ID: 15713479
• The Gordon Wilson Lecture: Using Genetic Medicine to Regenerate Diseased Organs and Protect Against the Hostile Environment
  Transactions of the American Clinical and Climatological Association. 2004  |   Pubmed ID: 17060966
• The Importance of Intrinsic Disorder for Protein Phosphorylation
  Nucleic Acids Research. 2004  |   Pubmed ID: 14960716
• Sampling-dependent Up-regulation of Gene Expression in Sequential Samples of Human Airway Epithelial Cells
  Molecular Medicine (Cambridge, Mass.). Sep-Dec, 2003  |   Pubmed ID: 15208741
• Serum Alpha-fetoprotein Screening for Hepatoblastoma in Children with Beckwith-Wiedemann Syndrome or Isolated Hemihyperplasia
  The Journal of Pediatrics. Aug, 2003  |   Pubmed ID: 12970646
• Human Thymine DNA Glycosylase (TDG) and Methyl-CpG-binding Protein 4 (MBD4) Excise Thymine Glycol (Tg) from a Tg:G Mispair
  Nucleic Acids Research. Sep, 2003  |   Pubmed ID: 12954776
• Efficient Repair of Cyclobutane Pyrimidine Dimers at Mutational Hot Spots is Restored in Complemented Xeroderma Pigmentosum Group C and Trichothiodystrophy/xeroderma Pigmentosum Group D Cells
  Journal of Molecular Biology. Sep, 2003  |   Pubmed ID: 12948486
• The Tibial-1 Pioneer Pathway: an in Vivo Model for Neuronal Outgrowth and Guidance
  Methods in Cell Biology. 2003  |   Pubmed ID: 12884692
• Chronic Intrauterine Pulmonary Hypertension Compromises Fetal Pulmonary Artery Smooth Muscle Cell O2 Sensing
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2003  |   Pubmed ID: 12882761
• Variability of Antioxidant-related Gene Expression in the Airway Epithelium of Cigarette Smokers
  American Journal of Respiratory Cell and Molecular Biology. Sep, 2003  |   Pubmed ID: 12702543
• Stability, Miscoding Potential, and Repair of 2'-deoxyxanthosine in DNA: Implications for Nitric Oxide-induced Mutagenesis
  Biochemistry. Apr, 2003  |   Pubmed ID: 12653565
• Gradients and Growth Cone Guidance of Grasshopper Neurons
  The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Apr, 2003  |   Pubmed ID: 12642623
• Role of Integrin-linked Kinase in Nerve Growth Factor-stimulated Neurite Outgrowth
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2003  |   Pubmed ID: 12629168
• Gradient Steepness Influences the Pathfinding Decisions of Neuronal Growth Cones in Vivo
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2003  |   Pubmed ID: 12514216
• MBD3L1 and MBD3L2, Two New Proteins Homologous to the Methyl-CpG-binding Proteins MBD2 and MBD3: Characterization of MBD3L1 As a Testis-specific Transcriptional Repressor
  Genomics. Dec, 2002  |   Pubmed ID: 12504854
• Migrating Mesoderm Establish a Uniform Distribution of Laminin in the Developing Grasshopper Embryo
  Developmental Biology. Sep, 2002  |   Pubmed ID: 12217318
• Oxidative DNA Damage Induced by Copper and Hydrogen Peroxide Promotes CG-->TT Tandem Mutations at Methylated CpG Dinucleotides in Nucleotide Excision Repair-deficient Cells
  Nucleic Acids Research. Aug, 2002  |   Pubmed ID: 12177298
• A High Isoflavone Soy Protein Diet and Intravenous Genistein Delay Rejection of Rat Cardiac Allografts
  The Journal of Nutrition. Aug, 2002  |   Pubmed ID: 12163676
• Intrathymic Kidney Cells Delay the Onset of Lupus Nephritis in MRL-lpr/lpr Mice
  International Immunology. Aug, 2002  |   Pubmed ID: 12147623
• Loads, Capacities and Safety Factors of Maltase and the Glucose Transporter SGLT1 in Mouse Intestinal Brush Border
  The Journal of Physiology. Jul, 2002  |   Pubmed ID: 12122147