Tobin J. Dickerson Department of Chemistry The Scripps Research Institute Biography Publications Institution JoVE Articles Tobin J. Dickerson has not added a biography. If you are Tobin J. Dickerson and would like to personalize this page please email our Author Liaison for assistance. Publications Microsphere-based Immunoassay for the Detection of Azaspiracids Analytical Biochemistry. Nov, 2013 | Pubmed ID: 24215909 Mephedrone (4-methylmethcathinone) Supports Intravenous Self-administration in Sprague-Dawley and Wistar Rats Addiction Biology. Sep, 2013 | Pubmed ID: 23363010 Effect of Ambient Temperature on the Thermoregulatory and Locomotor Stimulant Effects of 4-methylmethcathinone in Wistar and Sprague-Dawley Rats PloS One. 2012 | Pubmed ID: 22952999 Contrasting Effects of D-methamphetamine, 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxypyrovalerone, and 4-methylmethcathinone on Wheel Activity in Rats Drug and Alcohol Dependence. Nov, 2012 | Pubmed ID: 22664136 Reexamining Hydroxamate Inhibitors of Botulinum Neurotoxin Serotype A: Extending Towards the β-exosite Bioorganic & Medicinal Chemistry Letters. Jun, 2012 | Pubmed ID: 22542019 A Coincidence Detector Triggers Botulinum Neurotoxin Translocation Future Microbiology. Feb, 2012 | Pubmed ID: 22324987 Enhancing the Pharmacokinetic Properties of Botulinum Neurotoxin Serotype A Protease Inhibitors Through Rational Design ACS Chemical Neuroscience. Jun, 2011 | Pubmed ID: 21743830 Characterization of Differences Between Blood Sample Matrices in Untargeted Metabolomics Analytical Chemistry. Feb, 2011 | Pubmed ID: 21175165 Sensing the Deadliest Toxin: Technologies for Botulinum Neurotoxin Detection Toxins. Jan, 2010 | Pubmed ID: 22069545 Metabolomics-based Discovery of Diagnostic Biomarkers for Onchocerciasis PLoS Neglected Tropical Diseases. 2010 | Pubmed ID: 20957145 A Bacteriophage-based Platform for Rapid Trace Detection of Proteases Journal of the American Chemical Society. Sep, 2010 | Pubmed ID: 20812737 A Critical Evaluation of a Nicotine Vaccine Within a Self-administration Behavioral Model Molecular Pharmaceutics. Apr, 2010 | Pubmed ID: 20104903 Monoclonal Antibodies with Orthogonal Azaspiracid Epitopes Chembiochem : a European Journal of Chemical Biology. Jul, 2009 | Pubmed ID: 19492388 Drugs of Abuse That Mediate Advanced Glycation End Product Formation: a Chemical Link to Disease Pathology Accounts of Chemical Research. May, 2009 | Pubmed ID: 19275211 Bimodal Modulation of the Botulinum Neurotoxin Protein-conducting Channel Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19164566 Predicting Protein Evolution in Vitro by Phage Escape Technology Molecular BioSystems. Feb, 2009 | Pubmed ID: 19156257 Function-oriented Synthesis Applied to the Anti-botulinum Natural Product Toosendanin Bioorganic & Medicinal Chemistry. Feb, 2009 | Pubmed ID: 19131252 Prevention of Drug-induced Memory Impairment by Immunopharmacotherapy Journal of Medicinal Chemistry. Nov, 2008 | Pubmed ID: 18921991 The Strange Case of the Botulinum Neurotoxin: Using Chemistry and Biology to Modulate the Most Deadly Poison Angewandte Chemie (International Ed. in English). 2008 | Pubmed ID: 18844202 Major Sperm Protein As a Diagnostic Antigen for Onchocerciasis Bioorganic & Medicinal Chemistry. Aug, 2008 | Pubmed ID: 18632276 Interspecies and Interkingdom Communication Mediated by Bacterial Quorum Sensing Chemical Society Reviews. Jul, 2008 | Pubmed ID: 18568160 Biologically Templated Organic Polymers with Nanoscale Order Proceedings of the National Academy of Sciences of the United States of America. Feb, 2008 | Pubmed ID: 18216240 Nornicotine-organocatalyzed Aqueous Reduction of Alpha,beta-unsaturated Aldehydes Chemical Communications (Cambridge, England). Dec, 2007 | Pubmed ID: 18361380 Investigating Novel Therapeutic Targets and Molecular Mechanisms to Treat Botulinum Neurotoxin A Intoxication Future Microbiology. Dec, 2007 | Pubmed ID: 18041908 Synthesis and Structure-activity Relationships of Second-generation Hydroxamate Botulinum Neurotoxin A Protease Inhibitors Bioorganic & Medicinal Chemistry Letters. Dec, 2007 | Pubmed ID: 17951059 NMR Detection of Adventitious Xylose Binding to the Quorum-sensing Protein SdiA of Escherichia Coli Bioorganic & Medicinal Chemistry Letters. Nov, 2007 | Pubmed ID: 17889538 Phage Escape Libraries for Checkmate Analysis Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17646645 Self-vaccination by Methamphetamine Glycation Products Chemically Links Chronic Drug Abuse and Cardiovascular Disease Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17592122 Positional Linker Effects in Haptens for Cocaine Immunopharmacotherapy Bioorganic & Medicinal Chemistry Letters. Aug, 2007 | Pubmed ID: 17531484 Antibody-catalyzed Oxidation of Delta(9)-tetrahydrocannabinol Journal of the American Chemical Society. Mar, 2007 | Pubmed ID: 17335216 Technological Advancements for the Detection of and Protection Against Biological and Chemical Warfare Agents Chemical Society Reviews. Mar, 2007 | Pubmed ID: 17325785 An in Vitro and in Vivo Disconnect Uncovered Through High-throughput Identification of Botulinum Neurotoxin A Antagonists Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17293454 The Use of Small Molecules to Investigate Molecular Mechanisms and Therapeutic Targets for Treatment of Botulinum Neurotoxin A Intoxication ACS Chemical Biology. Jul, 2006 | Pubmed ID: 17163773 A Molecular Link Between the Active Component of Marijuana and Alzheimer's Disease Pathology Molecular Pharmaceutics. Nov-Dec, 2006 | Pubmed ID: 17140265 Unexpected Acetylcholinesterase Activity of Cocaine Esterases Journal of the American Chemical Society. Dec, 2006 | Pubmed ID: 17131989 Enamine-based Aldol Organocatalysis in Water: Are They Really "all Wet"? Angewandte Chemie (International Ed. in English). Dec, 2006 | Pubmed ID: 17001595 Superactivation of the Botulinum Neurotoxin Serotype A Light Chain Metalloprotease: a New Wrinkle in Botulinum Neurotoxin Journal of the American Chemical Society. Apr, 2006 | Pubmed ID: 16568962 Emerging Chemical and Biological Approaches for the Preparation of Discovery Libraries Drug Discovery Today. Feb, 2006 | Pubmed ID: 16533712 Complete Reaction Cycle of a Cocaine Catalytic Antibody at Atomic Resolution Structure (London, England : 1993). Feb, 2006 | Pubmed ID: 16472740 Structure of the Escherichia Coli Quorum Sensing Protein SdiA: Activation of the Folding Switch by Acyl Homoserine Lactones Journal of Molecular Biology. Jan, 2006 | Pubmed ID: 16307757 Recent Advances for the Treatment of Cocaine Abuse: Central Nervous System Immunopharmacotherapy The AAPS Journal. 2005 | Pubmed ID: 16353936 A Site-specific Bifunctional Protein Labeling System for Affinity and Fluorescent Analysis Bioconjugate Chemistry. Nov-Dec, 2005 | Pubmed ID: 16287229 Discovery of Acetylcholinesterase Peripheral Anionic Site Ligands Through Computational Refinement of a Directed Library Biochemistry. Nov, 2005 | Pubmed ID: 16274232 Vitamin B2-mediated Cellular Photoinhibition of Botulinum Neurotoxin A FEBS Letters. Oct, 2005 | Pubmed ID: 16198354 Altered Retinoid Homeostasis Catalyzed by a Nicotine Metabolite: Implications in Macular Degeneration and Normal Development Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 16014706 Toward Cocaine Esterase Therapeutics Journal of the American Chemical Society. Jul, 2005 | Pubmed ID: 16011362 Bacteriophage-mediated Protein Delivery into the Central Nervous System and Its Application in Immunopharmacotherapy Expert Opinion on Biological Therapy. Jun, 2005 | Pubmed ID: 15952908 Hammett Correlation of Nornicotine Analogues in the Aqueous Aldol Reaction: Implications for Green Organocatalysis The Journal of Organic Chemistry. Apr, 2005 | Pubmed ID: 15845010 Enantioreversal in the Sharpless Asymmetric Epoxidation Reaction Controlled by the Molecular Weight of a Covalently Appended Achiral Polymer The Journal of Organic Chemistry. Mar, 2005 | Pubmed ID: 15730294 Revisiting Quorum Sensing: Discovery of Additional Chemical and Biological Functions for 3-oxo-N-acylhomoserine Lactones Proceedings of the National Academy of Sciences of the United States of America. Jan, 2005 | Pubmed ID: 15623555 A Precipitator for the Detection of Thiophilic Metals in Aqua Journal of the American Chemical Society. Dec, 2004 | Pubmed ID: 15600364 Nornicotine Aqueous Aldol Reactions: Synthetic and Theoretical Investigations into the Origins of Catalysis The Journal of Organic Chemistry. Oct, 2004 | Pubmed ID: 15387581 Immunological Consequences of Methamphetamine Protein Glycation Journal of the American Chemical Society. Sep, 2004 | Pubmed ID: 15366884 Antibody-catalyzed Oxidative Degradation of Nicotine Using Riboflavin Bioorganic & Medicinal Chemistry. Sep, 2004 | Pubmed ID: 15336277 Catalysis of the Photo-Fries Reaction: Antibody-mediated Stabilization of High Energy States Journal of the American Chemical Society. Dec, 2003 | Pubmed ID: 14664584 Glycation of the Amyloid Beta-protein by a Nicotine Metabolite: a Fortuitous Chemical Dynamic Between Smoking and Alzheimer's Disease Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12815102 High-resolution Diffusion-ordered Spectroscopy to Probe the Microenvironment of JandaJel and Merrifield Resins The Journal of Organic Chemistry. May, 2003 | Pubmed ID: 12713377 A Previously Undescribed Chemical Link Between Smoking and Metabolic Disease Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002 | Pubmed ID: 12403823 Soluble Polymers As Scaffolds for Recoverable Catalysts and Reagents Chemical Reviews. Oct, 2002 | Pubmed ID: 12371887 Aqueous Aldol Catalysis by a Nicotine Metabolite Journal of the American Chemical Society. Apr, 2002 | Pubmed ID: 11916401 En High-throughput-kompatible FRET-baseret platform til identifikation og karakterisering af botulinumneurotoksin lyskæde modulatorer Dejan Caglič1, Kristin M. Bompiani1, Michelle C. Krutein1, Petr Čapek1, Tobin J. Dickerson1,2 1Department of Chemistry, The Scripps Research Institute, 2Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute Chemistry
En High-throughput-kompatible FRET-baseret platform til identifikation og karakterisering af botulinumneurotoksin lyskæde modulatorer Dejan Caglič1, Kristin M. Bompiani1, Michelle C. Krutein1, Petr Čapek1, Tobin J. Dickerson1,2 1Department of Chemistry, The Scripps Research Institute, 2Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute Chemistry