Tommy Alain

Publications

• Multifaceted Regulation of Somatic Cell Reprogramming by MRNA Translational Control
  Cell Stem Cell. May, 2014  |   Pubmed ID: 24630793
• Control of Paip1-eukayrotic Translation Initiation Factor 3 Interaction by Amino Acids Through S6 Kinase
  Molecular and Cellular Biology. Mar, 2014  |   Pubmed ID: 24396066
• MTORC1 Controls Mitochondrial Activity and Biogenesis Through 4E-BP-dependent Translational Regulation
  Cell Metabolism. Nov, 2013  |   Pubmed ID: 24206664
• Translational Control of Entrainment and Synchrony of the Suprachiasmatic Circadian Clock by MTOR/4E-BP1 Signaling
  Neuron. Aug, 2013  |   Pubmed ID: 23972597
• Control of Translation and MiRNA-dependent Repression by a Novel Poly(A) Binding Protein, HnRNP-Q
  PLoS Biology. 2013  |   Pubmed ID: 23700384
• Degradation of Newly Synthesized Polypeptides by Ribosome-associated RACK1/c-Jun N-terminal Kinase/eukaryotic Elongation Factor 1A2 Complex
  Molecular and Cellular Biology. Jul, 2013  |   Pubmed ID: 23608534
• MTOR Inhibitor Efficacy is Determined by the EIF4E/4E-BP Ratio
  Oncotarget. Dec, 2012  |   Pubmed ID: 23455427
• EIF4E/4E-BP Ratio Predicts the Efficacy of MTOR Targeted Therapies
  Cancer Research. Dec, 2012  |   Pubmed ID: 23100465
• A Novel 4EHP-GIGYF2 Translational Repressor Complex is Essential for Mammalian Development
  Molecular and Cellular Biology. Sep, 2012  |   Pubmed ID: 22751931
• Distinct Perturbation of the Translatome by the Antidiabetic Drug Metformin
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2012  |   Pubmed ID: 22611195
• Translational Control of the Activation of Transcription Factor NF-κB and Production of Type I Interferon by Phosphorylation of the Translation Factor EIF4E
  Nature Immunology. Jun, 2012  |   Pubmed ID: 22544393
• Analyse De La Structure Et L'activité De La Niclosamide Révèle Un Rôle Potentiel Pour PH Cytoplasmique Contrôle De Mammalian Target of Rapamycin (mTORC1) 1 Complexe De Signalisation
  The Journal of Biological Chemistry. May, 2012  |   Pubmed ID: 22474287
• IL-15 Can Signal Via IL-15Rα, JNK, and NF-κB to Drive RANTES Production by Myeloid Cells
  Journal of Immunology (Baltimore, Md. : 1950). May, 2012  |   Pubmed ID: 22447977
• Virus-tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-triggered Caspase-2 Cell Death
  Cancer Cell. Oct, 2011  |   Pubmed ID: 22014571
• Pharmacological and Genetic Evaluation of Proposed Roles of Mitogen-activated Protein Kinase/extracellular Signal-regulated Kinase Kinase (MEK), Extracellular Signal-regulated Kinase (ERK), and P90(RSK) in the Control of MTORC1 Protein Signaling by Phorbol Esters
  The Journal of Biological Chemistry. Aug, 2011  |   Pubmed ID: 21659537
• MTORC1-mediated Cell Proliferation, but Not Cell Growth, Controlled by the 4E-BPs
  Science (New York, N.Y.). May, 2010  |   Pubmed ID: 20508131
• Synergistic Effects Between Analogs of DNA and RNA Improve the Potency of SiRNA-mediated Gene Silencing
  Nucleic Acids Research. Jul, 2010  |   Pubmed ID: 20413581
• Vésiculaire Oncolyse Virus De La Stomatite Est Potentialisée Par L'altération MTORC1-dépendant De Type I La Production D'IFN
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010  |   Pubmed ID: 20080710
• Myxoma Virus Virotherapy for Glioma in Immunocompetent Animal Models: Optimizing Administration Routes and Synergy with Rapamycin
  Cancer Research. Jan, 2010  |   Pubmed ID: 20068158
• Susceptibility of Mantle Cell Lymphomas to Reovirus Oncolysis
  Leukemia Research. Jan, 2010  |   Pubmed ID: 19651440
• The Helicase Protein DHX29 Promotes Translation Initiation, Cell Proliferation, and Tumorigenesis
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009  |   Pubmed ID: 20018725
• P53-dependent Translational Control of Senescence and Transformation Via 4E-BPs
  Cancer Cell. Nov, 2009  |   Pubmed ID: 19878875
• Transcription Factors Down-stream of Ras As Molecular Indicators for Targeting Malignancies with Oncolytic Herpes Virus
  Molecular Oncology. Dec, 2009  |   Pubmed ID: 19766068
• Targeting Human Medulloblastoma: Oncolytic Virotherapy with Myxoma Virus is Enhanced by Rapamycin
  Cancer Research. Sep, 2007  |   Pubmed ID: 17875723
• Proteolytic Disassembly is a Critical Determinant for Reovirus Oncolysis
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2007  |   Pubmed ID: 17519890
• Effets Administré Par Voie Intraveineuse Virus Recombinant La Stomatite Vésiculaire (VSV (deltaM51)) Sur Gliomes Multifocaux Et Envahissantes
  Journal of the National Cancer Institute. Nov, 2006  |   Pubmed ID: 17077357
• Myxoma Virus is a Novel Oncolytic Virus with Significant Antitumor Activity Against Experimental Human Gliomas
  Cancer Research. Nov, 2005  |   Pubmed ID: 16267023
• Stromelysin-2 (matrix Metalloproteinase 10) is Inducible in Lymphoma Cells and Accelerates the Growth of Lymphoid Tumors in Vivo
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2004  |   Pubmed ID: 15356104
• Lymphomas and Oncolytic Virus Therapy
  Clinical Lymphoma. Sep, 2003  |   Pubmed ID: 14556682
• Reovirus Therapy of Lymphoid Malignancies
  Blood. Dec, 2002  |   Pubmed ID: 12393565
• Oncolytic Reovirus Against Ovarian and Colon Cancer
  Cancer Research. Mar, 2002  |   Pubmed ID: 11912142