Toshiaki Kawakami

Publications

• Kimishige Ishizaka 1925-2018
  Nature Immunology. Sep, 2018  |   Pubmed ID: 30104631
• PAI1 Mediates Fibroblast-mast Cell Interactions in Skin Fibrosis
  The Journal of Clinical Investigation. May, 2018  |   Pubmed ID: 29584619
• LIGHT-HVEM Signaling in Keratinocytes Controls Development of Dermatitis
  The Journal of Experimental Medicine. Feb, 2018  |   Pubmed ID: 29339444
• Crystal Structures of Murine and Human Histamine-Releasing Factor (HRF/TCTP) and a Model for HRF Dimerisation in Mast Cell Activation
  Molecular Immunology. Jan, 2018  |   Pubmed ID: 29216544
• Histamine-releasing Factor Enhances Food Allergy
  The Journal of Clinical Investigation. Dec, 2017  |   Pubmed ID: 29130935
• TWEAK Mediates Inflammation in Experimental Atopic Dermatitis and Psoriasis
  Nature Communications. May, 2017  |   Pubmed ID: 28530223
• Role of Histamine-releasing Factor in Allergic Inflammatory Reactions
  Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 2017  |   Pubmed ID: 28458281
• Skin Microbiome Promotes Mast Cell Maturation by Triggering Stem Cell Factor Production in Keratinocytes
  The Journal of Allergy and Clinical Immunology. Apr, 2017  |   Pubmed ID: 27746235
• Defective Natural Killer Cell Activity in a Mouse Model of Eczema Herpeticum
  The Journal of Allergy and Clinical Immunology. Mar, 2017  |   Pubmed ID: 27476888
• From IgE to Omalizumab
  Journal of Immunology (Baltimore, Md. : 1950). 12, 2016  |   Pubmed ID: 27864548
• Guanine Nucleotide Exchange Factor RABGEF1 Regulates Keratinocyte-intrinsic Signaling to Maintain Skin Homeostasis
  The Journal of Clinical Investigation. Dec, 2016  |   Pubmed ID: 27820702
• Differentiate or Die!
  Nature Immunology. 08, 2016  |   Pubmed ID: 27540982
• Signal Transduction and Chemotaxis in Mast Cells
  European Journal of Pharmacology. May, 2016  |   Pubmed ID: 25941081
• Hypothetical Atopic Dermatitis-Myeloproliferative Neoplasm Syndrome
  Frontiers in Immunology. 2015  |   Pubmed ID: 26379670
• Mast Cells and Dendritic Cells Form Synapses That Facilitate Antigen Transfer for T Cell Activation
  The Journal of Cell Biology. Aug, 2015  |   Pubmed ID: 26304724
• A Mouse Model of Atopic Dermatitis
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 25388270
• Basic Techniques to Study FcεRI Signaling in Mast Cells
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 25388253
• Critical Role for Mast Cell Stat5 Activity in Skin Inflammation
  Cell Reports. Jan, 2014  |   Pubmed ID: 24412367
• Histamine-releasing Factor and Immunoglobulins in Asthma and Allergy
  Allergy, Asthma & Immunology Research. Jan, 2014  |   Pubmed ID: 24404387
• Salmonella's Masterful Skill in Mast Cell Suppression
  Immunity. Dec, 2013  |   Pubmed ID: 24332026
• Phospholipase C-β in Immune Cells
  Advances in Biological Regulation. Sep, 2013  |   Pubmed ID: 23981313
• Mast Cells Are Required for Full Expression of Allergen/SEB-induced Skin Inflammation
  The Journal of Investigative Dermatology. Dec, 2013  |   Pubmed ID: 23752044
• Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens
  Allergy, Asthma & Immunology Research. Nov, 2012  |   Pubmed ID: 23115729
• A Novel Role for the Transcription Factor HIF-1α in the Formation of Mast Cell Extracellular Traps
  The Biochemical Journal. Aug, 2012  |   Pubmed ID: 22738198
• Human FcγRIIA at Center Stage
  Blood. Mar, 2012  |   Pubmed ID: 22422810
• Histamine-releasing Factor Has a Proinflammatory Role in Mouse Models of Asthma and Allergy
  The Journal of Clinical Investigation. Jan, 2012  |   Pubmed ID: 22133880
• Regulation of Proliferation, Survival, Differentiation, and Activation by the Signaling Platform for SHP-1 Phosphatase
  Advances in Biological Regulation. Jan, 2012  |   Pubmed ID: 21982978
• Short Stat5-interacting Peptide Derived from Phospholipase C-β3 Inhibits Hematopoietic Cell Proliferation and Myeloid Differentiation
  PloS One. 2011  |   Pubmed ID: 21949826
• IgE Stimulates Human and Mouse Arterial Cell Apoptosis and Cytokine Expression and Promotes Atherogenesis in Apoe-/- Mice
  The Journal of Clinical Investigation. Sep, 2011  |   Pubmed ID: 21821913
• Monomeric IgE and Mast Cell Development, Survival and Function
  Advances in Experimental Medicine and Biology. 2011  |   Pubmed ID: 21713650
• Phospholipase C-β3 Regulates FcɛRI-mediated Mast Cell Activation by Recruiting the Protein Phosphatase SHP-1
  Immunity. Jun, 2011  |   Pubmed ID: 21683628
• Protective Murine and Human Monoclonal Antibodies Against Eczema Vaccinatum
  Antiviral Therapy. 2011  |   Pubmed ID: 21311110
• JNK1 Controls Mast Cell Degranulation and IL-1{beta} Production in Inflammatory Arthritis
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010  |   Pubmed ID: 21135226
• Lyn- and PLC-beta3-dependent Regulation of SHP-1 Phosphorylation Controls Stat5 Activity and Myelomonocytic Leukemia-like Disease
  Blood. Dec, 2010  |   Pubmed ID: 20858858
• A Minor Catalytic Activity of Src Family Kinases is Sufficient for Maximal Activation of Mast Cells Via the High-affinity IgE Receptor
  Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010  |   Pubmed ID: 19949072
• A Crucial Door to the Mast Cell Mystery Knocked In
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2009  |   Pubmed ID: 19923472
• Mast Cells in Atopic Dermatitis
  Current Opinion in Immunology. Dec, 2009  |   Pubmed ID: 19828304
• Small, Mobile FcepsilonRI Receptor Aggregates Are Signaling Competent
  Immunity. Sep, 2009  |   Pubmed ID: 19747859
• Tumor Suppression by Phospholipase C-beta3 Via SHP-1-mediated Dephosphorylation of Stat5
  Cancer Cell. Aug, 2009  |   Pubmed ID: 19647226
• Polyclonal IgE Induces Mast Cell Survival and Cytokine Production
  Allergology International : Official Journal of the Japanese Society of Allergology. Sep, 2009  |   Pubmed ID: 19542764
• Inhibition of NK Cell Activity by IL-17 Allows Vaccinia Virus to Induce Severe Skin Lesions in a Mouse Model of Eczema Vaccinatum
  The Journal of Experimental Medicine. Jun, 2009  |   Pubmed ID: 19468065
• Allergen-independent Immunomodulatory Activities of Immunoglobulin E
  Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology. Mar, 2009  |   Pubmed ID: 19178542
• Pivotal Advance: IgE Accelerates in Vitro Development of Mast Cells and Modifies Their Phenotype
  Journal of Leukocyte Biology. Aug, 2008  |   Pubmed ID: 18477690
• Regulation of Myeloproliferation and M2 Macrophage Programming in Mice by Lyn/Hck, SHIP, and Stat5
  The Journal of Clinical Investigation. Mar, 2008  |   Pubmed ID: 18246197
• An Improved Mouse Model of Atopic Dermatitis and Suppression of Skin Lesions by an Inhibitor of Tec Family Kinases
  Allergology International : Official Journal of the Japanese Society of Allergology. Dec, 2007  |   Pubmed ID: 17713360
• The Src Family Kinase Hck Regulates Mast Cell Activation by Suppressing an Inhibitory Src Family Kinase Lyn
  Blood. Oct, 2007  |   Pubmed ID: 17513616
• Dysregulation of Src Family Kinases in Mast Cells from Epilepsy-resistant ASK Versus Epilepsy-prone EL Mice
  Journal of Immunology (Baltimore, Md. : 1950). Jan, 2007  |   Pubmed ID: 17182584
• Development, Migration, and Survival of Mast Cells
  Immunologic Research. 2006  |   Pubmed ID: 16760571
• Regulation of Dendritic Cell Maturation and Function by Bruton's Tyrosine Kinase Via IL-10 and Stat3
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006  |   Pubmed ID: 16371463
• Techniques to Study Fc EpsilonRI Signaling
  Methods in Molecular Biology (Clifton, N.J.). 2006  |   Pubmed ID: 16110158
• IgE Regulation of Mast Cell Survival and Function
  Novartis Foundation Symposium. 2005  |   Pubmed ID: 16605130
• Positive and Negative Regulation of Mast Cell Activation by Lyn Via the FcepsilonRI
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2005  |   Pubmed ID: 16272347
• Mast Cell Survival and Activation by IgE in the Absence of Antigen: a Consideration of the Biologic Mechanisms and Relevance
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2005  |   Pubmed ID: 16177053
• Costimulation of Mast Cells by 4-1BB, a Member of the Tumor Necrosis Factor Receptor Superfamily, with the High-affinity IgE Receptor
  Blood. Dec, 2005  |   Pubmed ID: 16123219
• Regulation of Highly Cytokinergic IgE-induced Mast Cell Adhesion by Src, Syk, Tec, and Protein Kinase C Family Kinases
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2005  |   Pubmed ID: 15814670
• IgE- and IgE+Ag-mediated Mast Cell Migration in an Autocrine/paracrine Fashion
  Blood. Apr, 2005  |   Pubmed ID: 15637135
• Critical Role for Galectin-3 in Airway Inflammation and Bronchial Hyperresponsiveness in a Murine Model of Asthma
  The American Journal of Pathology. Dec, 2004  |   Pubmed ID: 15579447
• Early Divergence of Fc Epsilon Receptor I Signals for Receptor Up-regulation and Internalization from Degranulation, Cytokine Production, and Survival
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2004  |   Pubmed ID: 15383560
• Protein Kinase C BetaII Regulates Akt Phosphorylation on Ser-473 in a Cell Type- and Stimulus-specific Fashion
  The Journal of Biological Chemistry. Nov, 2004  |   Pubmed ID: 15364915
• [Regulation of Mast Cell Survival and Activation by Monomeric IgE]
  Arerugi = [Allergy]. Jun, 2004  |   Pubmed ID: 15247516
• Evidence That IgE Molecules Mediate a Spectrum of Effects on Mast Cell Survival and Activation Via Aggregation of the FcepsilonRI
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003  |   Pubmed ID: 14569021
• A Ras Activation Pathway Dependent on Syk Phosphorylation of Protein Kinase C
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2003  |   Pubmed ID: 12881490
• Protein Kinase C Beta (PKC Beta): Normal Functions and Diseases
  Journal of Biochemistry. Nov, 2002  |   Pubmed ID: 12417015
• Regulation of Mast-cell and Basophil Function and Survival by IgE
  Nature Reviews. Immunology. Oct, 2002  |   Pubmed ID: 12360215
• PKCbeta Modulates Antigen Receptor Signaling Via Regulation of Btk Membrane Localization
  The EMBO Journal. Oct, 2001  |   Pubmed ID: 11598012
• Akt-dependent Cytokine Production in Mast Cells
  The Journal of Experimental Medicine. Sep, 2000  |   Pubmed ID: 10974038
• Regulation of Protein Kinase CbetaI by Two Protein-tyrosine Kinases, Btk and Syk
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2000  |   Pubmed ID: 10852954
• Terreic Acid, a Quinone Epoxide Inhibitor of Bruton's Tyrosine Kinase
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 1999  |   Pubmed ID: 10051623
• Involvement of Bruton's Tyrosine Kinase in FcepsilonRI-dependent Mast Cell Degranulation and Cytokine Production
  The Journal of Experimental Medicine. Apr, 1998  |   Pubmed ID: 9547335
• Bruton's Tyrosine Kinase Regulates Apoptosis and JNK/SAPK Kinase Activity
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 1997  |   Pubmed ID: 9108083