Tsuyoshi Miyakawa Biography Publications JoVE Articles Tsuyoshi Miyakawa has not added a biography. If you are Tsuyoshi Miyakawa and would like to personalize this page please email our Author Liaison for assistance. Publications Reply to Warren Et Al. and Shay Et Al.: Commonalities Across Species Do Exist and Are Potentially Important Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25540421 Genomic Responses in Mouse Models Greatly Mimic Human Inflammatory Diseases Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25092317 IL1RAPL1 Knockout Mice Show Spine Density Decrease, Learning Deficiency, Hyperactivity and Reduced Anxiety-like Behaviours Scientific Reports. 2014 | Pubmed ID: 25312502 Transient Receptor Potential Ankyrin 1 in Spinal Cord Dorsal Horn is Involved in Neuropathic Pain in Nerve Root Constriction Rats Molecular Pain. 2014 | Pubmed ID: 25192906 SIRT1 Overexpression Ameliorates a Mouse Model of SOD1-linked Amyotrophic Lateral Sclerosis Via HSF1/HSP70i Chaperone System Molecular Brain. 2014 | Pubmed ID: 25167838 [Immaturity of Brain As an Endophenotype of Neuropsychiatric Disorders] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2014 | Pubmed ID: 25076776 Mechanisms for Interferon-α-induced Depression and Neural Stem Cell Dysfunction Stem Cell Reports. Jul, 2014 | Pubmed ID: 25068123 Enhanced Stability of Hippocampal Place Representation Caused by Reduced Magnesium Block of NMDA Receptors in the Dentate Gyrus Molecular Brain. 2014 | Pubmed ID: 24893573 Transcriptomic Evidence for Immaturity of the Prefrontal Cortex in Patients with Schizophrenia Molecular Brain. 2014 | Pubmed ID: 24886351 Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy Science (New York, N.Y.). May, 2014 | Pubmed ID: 24812394 Comprehensive Behavioral Study of MGluR3 Knockout Mice: Implication in Schizophrenia Related Endophenotypes Molecular Brain. 2014 | Pubmed ID: 24758191 Targeted Deletion of the C-terminus of the Mouse Adenomatous Polyposis Coli Tumor Suppressor Results in Neurologic Phenotypes Related to Schizophrenia Molecular Brain. 2014 | Pubmed ID: 24678719 Comprehensive Behavioral Analysis of Cluster of Differentiation 47 Knockout Mice PloS One. 2014 | Pubmed ID: 24586890 Increased Behavioral and Neuronal Responses to a Hallucinogenic Drug in PACAP Heterozygous Mutant Mice PloS One. 2014 | Pubmed ID: 24586556 Absence of BRINP1 in Mice Causes Increase of Hippocampal Neurogenesis and Behavioral Alterations Relevant to Human Psychiatric Disorders Molecular Brain. 2014 | Pubmed ID: 24528488 Microendoscopy-assisted Muscle-preserving Interlaminar Decompression for Lumbar Spinal Stenosis: Clinical Results of Consecutive 105 Cases with More Than 3-year Follow-up Spine. Mar, 2014 | Pubmed ID: 24365896 Mice Lacking Collapsin Response Mediator Protein 1 Manifest Hyperactivity, Impaired Learning and Memory, and Impaired Prepulse Inhibition Frontiers in Behavioral Neuroscience. 2013 | Pubmed ID: 24409129 PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders PloS One. 2013 | Pubmed ID: 24312498 In Vivo Evaluation of Cellular Activity in αCaMKII Heterozygous Knockout Mice Using Manganese-enhanced Magnetic Resonance Imaging (MEMRI) Frontiers in Integrative Neuroscience. 2013 | Pubmed ID: 24273499 Chronic Fluoxetine Treatment Reduces Parvalbumin Expression and Perineuronal Nets in Gamma-aminobutyric Acidergic Interneurons of the Frontal Cortex in Adult Mice Molecular Brain. 2013 | Pubmed ID: 24228616 Point Mutation in Syntaxin-1A Causes Abnormal Vesicle Recycling, Behaviors, and Short Term Plasticity The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24136198 Orexin Receptor-1 in the Locus Coeruleus Plays an Important Role in Cue-dependent Fear Memory Consolidation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2013 | Pubmed ID: 24005305 Chronic Overload of SEPT4, a Parkin Substrate That Aggregates in Parkinson's Disease, Causes Behavioral Alterations but Not Neurodegeneration in Mice Molecular Brain. 2013 | Pubmed ID: 23938054 Immature Dentate Gyrus: an Endophenotype of Neuropsychiatric Disorders Neural Plasticity. 2013 | Pubmed ID: 23840971 ENU-mutagenesis Mice with a Non-synonymous Mutation in Grin1 Exhibit Abnormal Anxiety-like Behaviors, Impaired Fear Memory, and Decreased Acoustic Startle Response BMC Research Notes. 2013 | Pubmed ID: 23688147 The Immature Dentate Gyrus Represents a Shared Phenotype of Mouse Models of Epilepsy and Psychiatric Disease Bipolar Disorders. Jun, 2013 | Pubmed ID: 23560889 Synaptosomal-associated Protein 25 Mutation Induces Immaturity of the Dentate Granule Cells of Adult Mice Molecular Brain. 2013 | Pubmed ID: 23497716 Post-natal Treatment by a Blood-brain-barrier Permeable Calpain Inhibitor, SNJ1945 Rescued Defective Function in Lissencephaly Scientific Reports. 2013 | Pubmed ID: 23390575 Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal, and Behavioral Phenotypes Related to Schizophrenia Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2013 | Pubmed ID: 23389689 Fluoxetine-induced Cortical Adult Neurogenesis Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. May, 2013 | Pubmed ID: 23303069 Increased Astrocytic ATP Release Results in Enhanced Excitability of the Hippocampus Glia. Feb, 2013 | Pubmed ID: 23018918 Behavioral Abnormalities Observed in Zfhx2-deficient Mice PloS One. 2012 | Pubmed ID: 23300874 Impaired Synaptic Clustering of Postsynaptic Density Proteins and Altered Signal Transmission in Hippocampal Neurons, and Disrupted Learning Behavior in PDZ1 and PDZ2 Ligand Binding-deficient PSD-95 Knockin Mice Molecular Brain. 2012 | Pubmed ID: 23268962 Comprehensive Behavioral Analysis of Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Knockout Mice Frontiers in Behavioral Neuroscience. 2012 | Pubmed ID: 23060763 α-Synuclein BAC Transgenic Mice As a Model for Parkinson's Disease Manifested Decreased Anxiety-like Behavior and Hyperlocomotion Neuroscience Research. Jun, 2012 | Pubmed ID: 22475625 M4 Muscarinic Receptor Knockout Mice Display Abnormal Social Behavior and Decreased Prepulse Inhibition Molecular Brain. 2012 | Pubmed ID: 22463818 Comprehensive Behavioral Analysis of ENU-induced Disc1-Q31L and -L100P Mutant Mice BMC Research Notes. Feb, 2012 | Pubmed ID: 22348257 Right-hemispheric Dominance of Spatial Memory in Split-brain Mice Hippocampus. Feb, 2012 | Pubmed ID: 21069782 Adenomatous Polyposis Coli Heterozygous Knockout Mice Display Hypoactivity and Age-dependent Working Memory Deficits Frontiers in Behavioral Neuroscience. 2011 | Pubmed ID: 22347851 DIP/WISH Deficiency Enhances Synaptic Function and Performance in the Barnes Maze Molecular Brain. 2011 | Pubmed ID: 22018352 Expression of the AMPA Receptor Subunits GluR1 and GluR2 is Associated with Granule Cell Maturation in the Dentate Gyrus Frontiers in Neuroscience. 2011 | Pubmed ID: 21927594 Relaxin-3-deficient Mice Showed Slight Alteration in Anxiety-related Behavior Frontiers in Behavioral Neuroscience. 2011 | Pubmed ID: 21887138 P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating PloS One. 2011 | Pubmed ID: 21698260 Forebrain-specific Constitutively Active CaMKKα Transgenic Mice Show Deficits in Hippocampus-dependent Long-term Memory Neurobiology of Learning and Memory. Sep, 2011 | Pubmed ID: 21558011 Synaptic E3 Ligase SCRAPPER in Contextual Fear Conditioning: Extensive Behavioral Phenotyping of Scrapper Heterozygote and Overexpressing Mutant Mice PloS One. 2011 | Pubmed ID: 21390313 Chronic Treatment with Fluoxetine for More Than 6 Weeks Decreases Neurogenesis in the Subventricular Zone of Adult Mice Molecular Brain. 2011 | Pubmed ID: 21385396 The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing Mice PloS One. 2011 | Pubmed ID: 21305033 Inactivation of Fibroblast Growth Factor Binding Protein 3 Causes Anxiety-related Behaviors Molecular and Cellular Neurosciences. Jan, 2011 | Pubmed ID: 20851768 Decreased Exploratory Activity in a Mouse Model of 15q Duplication Syndrome; Implications for Disturbance of Serotonin Signaling PloS One. 2010 | Pubmed ID: 21179543 Expression of Tryptophan 2,3-dioxygenase in Mature Granule Cells of the Adult Mouse Dentate Gyrus Molecular Brain. 2010 | Pubmed ID: 20815922 Stress-evoked Tyrosine Phosphorylation of Signal Regulatory Protein α Regulates Behavioral Immobility in the Forced Swim Test The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2010 | Pubmed ID: 20685990 Behavioral Profiles of Three C57BL/6 Substrains Frontiers in Behavioral Neuroscience. 2010 | Pubmed ID: 20676234 [Immature Dentate Gyrus As a Candidate Endophenotype of Psychiatric Disorders] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2010 | Pubmed ID: 20666142 Case Reports: Painful Limbs/moving Extremities: Report of Two Cases Clinical Orthopaedics and Related Research. Dec, 2010 | Pubmed ID: 20585912 A Mouse Model Characterizing Features of Vascular Dementia with Hippocampal Atrophy Stroke; a Journal of Cerebral Circulation. Jun, 2010 | Pubmed ID: 20448204 Reversal of Hippocampal Neuronal Maturation by Serotonergic Antidepressants Proceedings of the National Academy of Sciences of the United States of America. May, 2010 | Pubmed ID: 20404165 Comprehensive Behavioral Analysis of Calcium/calmodulin-dependent Protein Kinase IV Knockout Mice PloS One. 2010 | Pubmed ID: 20209163 SDOP-DB: a Comparative Standardized-protocol Database for Mouse Phenotypic Analyses Bioinformatics (Oxford, England). Apr, 2010 | Pubmed ID: 20194625 Ischemia-induced Neurogenesis of Neocortical Layer 1 Progenitor Cells Nature Neuroscience. Feb, 2010 | Pubmed ID: 20037576 Nardilysin Regulates Axonal Maturation and Myelination in the Central and Peripheral Nervous System Nature Neuroscience. Dec, 2009 | Pubmed ID: 19935654 Abnormalities in Brain Structure and Behavior in GSK-3alpha Mutant Mice Molecular Brain. 2009 | Pubmed ID: 19925672 KF-1 Ubiquitin Ligase: An Anxiety Suppressor Frontiers in Neuroscience. May, 2009 | Pubmed ID: 19753093 Neural Activity Changes Underlying the Working Memory Deficit in Alpha-CaMKII Heterozygous Knockout Mice Frontiers in Behavioral Neuroscience. 2009 | Pubmed ID: 19750198 Inhibition of Calpain Increases LIS1 Expression and Partially Rescues in Vivo Phenotypes in a Mouse Model of Lissencephaly Nature Medicine. Oct, 2009 | Pubmed ID: 19734909 Intrauterine Environment-genome Interaction and Children's Development (4): Brain-behavior Phenotypying of Genetically-engineered Mice Using a Comprehensive Behavioral Test Battery on Research of Neuropsychiatric Disorders The Journal of Toxicological Sciences. 2009 | Pubmed ID: 19571483 Mice with Altered Myelin Proteolipid Protein Gene Expression Display Cognitive Deficits Accompanied by Abnormal Neuron-glia Interactions and Decreased Conduction Velocities The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2009 | Pubmed ID: 19571127 Abnormal Behavior in a Chromosome-engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism Cell. Jun, 2009 | Pubmed ID: 19563756 Abnormal Social Behavior, Hyperactivity, Impaired Remote Spatial Memory, and Increased D1-mediated Dopaminergic Signaling in Neuronal Nitric Oxide Synthase Knockout Mice Molecular Brain. 2009 | Pubmed ID: 19538708 Comprehensive Behavioral Phenotyping of Ryanodine Receptor Type 3 (RyR3) Knockout Mice: Decreased Social Contact Duration in Two Social Interaction Tests Frontiers in Behavioral Neuroscience. 2009 | Pubmed ID: 19503748 [Genes, Behaviors and Psychiatric Disorders] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Mar, 2008 | Pubmed ID: 21089339 Normal Mitochondrial Respiratory Function is Essential for Spatial Remote Memory in Mice Molecular Brain. 2008 | Pubmed ID: 19087269 Down-regulation of Protocadherin-alpha A Isoforms in Mice Changes Contextual Fear Conditioning and Spatial Working Memory The European Journal of Neuroscience. Oct, 2008 | Pubmed ID: 18973563 Mice Lacking the Kf-1 Gene Exhibit Increased Anxiety- but Not Despair-like Behavior Frontiers in Behavioral Neuroscience. 2008 | Pubmed ID: 18958194 Impaired Long-term Memory Retention and Working Memory in Sdy Mutant Mice with a Deletion in Dtnbp1, a Susceptibility Gene for Schizophrenia Molecular Brain. 2008 | Pubmed ID: 18945333 Comprehensive Behavioral Phenotyping of Calpastatin-knockout Mice Molecular Brain. 2008 | Pubmed ID: 18803809 Alpha-CaMKII Deficiency Causes Immature Dentate Gyrus, a Novel Candidate Endophenotype of Psychiatric Disorders Molecular Brain. 2008 | Pubmed ID: 18803808 Roles of Continuous Neurogenesis in the Structural and Functional Integrity of the Adult Forebrain Nature Neuroscience. Oct, 2008 | Pubmed ID: 18758458 Identification of YWHAE, a Gene Encoding 14-3-3epsilon, As a Possible Susceptibility Gene for Schizophrenia Human Molecular Genetics. Oct, 2008 | Pubmed ID: 18658164 Mice Lacking the Schizophrenia-associated Protein FEZ1 Manifest Hyperactivity and Enhanced Responsiveness to Psychostimulants Human Molecular Genetics. Oct, 2008 | Pubmed ID: 18647754 [Investigating Genes-to-behavior Pathways in Psychiatric Diseases: an Approach Using a Comprehensive Behavioral Test Battery on Genetically Engineered Mice] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2008 | Pubmed ID: 18646600 Increased Anxiety-like Behavior in Neuropsin (kallikrein-related Peptidase 8) Gene-deficient Mice Behavioral Neuroscience. Jun, 2008 | Pubmed ID: 18513120 Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2008 | Pubmed ID: 18272690 Increased Social Interaction in Mice Deficient of the Striatal Medium Spiny Neuron-specific Phosphodiesterase 10A2 Journal of Neurochemistry. Apr, 2008 | Pubmed ID: 18088367 Genetic Ablation of NMDA Receptor Subunit NR3B in Mouse Reveals Motoneuronal and Nonmotoneuronal Phenotypes The European Journal of Neuroscience. Sep, 2007 | Pubmed ID: 17880385 Altered Sensitivities to Morphine and Cocaine in Scaffold Protein Tamalin Knockout Mice Proceedings of the National Academy of Sciences of the United States of America. Sep, 2007 | Pubmed ID: 17766434 Selective Impairment of Working Memory in a Mouse Model of Chronic Cerebral Hypoperfusion Stroke; a Journal of Cerebral Circulation. Oct, 2007 | Pubmed ID: 17761909 Impact of Brain-behavior Phenotypying of Genetically-engineered Mice on Research of Neuropsychiatric Disorders Neuroscience Research. Jun, 2007 | Pubmed ID: 17524507 Enriched Environments Influence Depression-related Behavior in Adult Mice and the Survival of Newborn Cells in Their Hippocampi Behavioural Brain Research. Jun, 2007 | Pubmed ID: 17397941 Mouse Liaison for Integrative Brain Research Neuroscience Research. Jun, 2007 | Pubmed ID: 17382419 Sept4, a Component of Presynaptic Scaffold and Lewy Bodies, is Required for the Suppression of Alpha-synuclein Neurotoxicity Neuron. Feb, 2007 | Pubmed ID: 17296554 Investigating Gene-to-behavior Pathways in Psychiatric Disorders: the Use of a Comprehensive Behavioral Test Battery on Genetically Engineered Mice Annals of the New York Academy of Sciences. Nov, 2006 | Pubmed ID: 17185513 Schizophrenia-relevant Behavioral Testing in Rodent Models: a Uniquely Human Disorder? Biological Psychiatry. Jun, 2006 | Pubmed ID: 16797265 NFAT Dysregulation by Increased Dosage of DSCR1 and DYRK1A on Chromosome 21 Nature. Jun, 2006 | Pubmed ID: 16554754 [Stress and Animal Model of Psychiatric Disease] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Sep, 2005 | Pubmed ID: 16272762 Tight Junctions in Schwann Cells of Peripheral Myelinated Axons: a Lesson from Claudin-19-deficient Mice The Journal of Cell Biology. May, 2005 | Pubmed ID: 15883201 Enhanced Cocaine Responsiveness and Impaired Motor Coordination in Metabotropic Glutamate Receptor Subtype 2 Knockout Mice Proceedings of the National Academy of Sciences of the United States of America. Mar, 2005 | Pubmed ID: 15753323 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2004 | Pubmed ID: 15537882 Acceleration of Visually Cued Conditioned Fear Through the Auditory Pathway Nature Neuroscience. Sep, 2004 | Pubmed ID: 15322551 Evidence for Association of Schizophrenia with Genetic Variation in the 8p21.3 Gene, PPP3CC, Encoding the Calcineurin Gamma Subunit Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12851458 Conditional Calcineurin Knockout Mice Exhibit Multiple Abnormal Behaviors Related to Schizophrenia Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12851457 Contextual and Cued Fear Conditioning Test Using a Video Analyzing System in Mice JoVE 50871 Behavior T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice JoVE 3300 Neuroscience Dissection of Hippocampal Dentate Gyrus from Adult Mouse JoVE 1543 Biology Elevated Plus Maze for Mice JoVE 1088 Biology Światło / ciemność test przejścia dla Myszy Keizo Takao1, Tsuyoshi Miyakawa1 1Genetic Engineering and Functional Genomics Unit, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University JoVE 104 Biology
Contextual and Cued Fear Conditioning Test Using a Video Analyzing System in Mice JoVE 50871 Behavior
T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice JoVE 3300 Neuroscience
Światło / ciemność test przejścia dla Myszy Keizo Takao1, Tsuyoshi Miyakawa1 1Genetic Engineering and Functional Genomics Unit, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University JoVE 104 Biology
