Uwe-Karsten Hanisch

Publications

• Zoledronic Acid Inhibits Macrophage/microglia-assisted Breast Cancer Cell Invasion
  Oncotarget. Aug, 2013  |   Pubmed ID: 24036536
• Toll-like Receptor 2 Mediates Microglia/brain Macrophage MT1-MMP Expression and Glioma Expansion
  Neuro-oncology. Oct, 2013  |   Pubmed ID: 24014382
• Empty Liposomes Induce Antitumoral Effects Associated with Macrophage Responses Distinct from Those of the TLR1/2 Agonist Pam3CSK 4 (BLP)
  Cancer Immunology, Immunotherapy : CII. Oct, 2013  |   Pubmed ID: 23917775
• Carcinoma Cells Misuse the Host Tissue Damage Response to Invade the Brain
  Glia. Aug, 2013  |   Pubmed ID: 23832647
• Functional Diversity of Microglia - How Heterogeneous Are They to Begin With?
  Frontiers in Cellular Neuroscience. 2013  |   Pubmed ID: 23717262
• Histone Deacetylase Inhibitors Suppress Immune Activation in Primary Mouse Microglia
  Journal of Neuroscience Research. Sep, 2013  |   Pubmed ID: 23686642
• Resistance of the Brain to Escherichia Coli K1 Infection Depends on MyD88 Signaling and the Contribution of Neutrophils and Monocytes
  Infection and Immunity. May, 2013  |   Pubmed ID: 23478323
• Proteins in Microglial Activation--inputs and Outputs by Subsets
  Current Protein & Peptide Science. Feb, 2013  |   Pubmed ID: 23441901
• Influence of Methylene Blue on Microglia-induced Inflammation and Motor Neuron Degeneration in the SOD1(G93A) Model for ALS
  PloS One. 2012  |   Pubmed ID: 22952827
• Toll-like Receptor Activation Reveals Developmental Reorganization and Unmasks Responder Subsets of Microglia
  Glia. Dec, 2012  |   Pubmed ID: 22911652
• The Nucleotide-binding Oligomerization Domain-containing-2 Ligand Muramyl Dipeptide Enhances Phagocytosis and Intracellular Killing of Escherichia Coli K1 by Toll-like Receptor Agonists in Microglial Cells
  Journal of Neuroimmunology. Nov, 2012  |   Pubmed ID: 22889567
• Complement Receptor-3 Negatively Regulates the Phagocytosis of Degenerated Myelin Through Tyrosine Kinase Syk and Cofilin
  Journal of Neuroinflammation. 2012  |   Pubmed ID: 22776089
• Reduced Astrocytic NF-κB Activation by Laquinimod Protects from Cuprizone-induced Demyelination
  Acta Neuropathologica. Sep, 2012  |   Pubmed ID: 22766690
• Expression of Coagulation Factors and Their Receptors in Tumor Tissue and Coagulation Factor Upregulation in Peripheral Blood of Patients with Cerebral Carcinoma Metastases
  Journal of Cancer Research and Clinical Oncology. Jan, 2012  |   Pubmed ID: 22065054
• Physiology of Microglia
  Physiological Reviews. Apr, 2011  |   Pubmed ID: 21527731
• Selective Transfer of Exosomes from Oligodendrocytes to Microglia by Macropinocytosis
  Journal of Cell Science. Feb, 2011  |   Pubmed ID: 21242314
• CD14 and TRIF Govern Distinct Responsiveness and Responses in Mouse Microglial TLR4 Challenges by Structural Variants of LPS
  Brain, Behavior, and Immunity. Jul, 2011  |   Pubmed ID: 20951794
• Inflammatory Cytokine Release of Astrocytes in Vitro is Reduced by All-trans Retinoic Acid
  Journal of Neuroimmunology. Dec, 2010  |   Pubmed ID: 20826012
• The Viral TLR3 Agonist Poly(I:C) Stimulates Phagocytosis and Intracellular Killing of Escherichia Coli by Microglial Cells
  Neuroscience Letters. Sep, 2010  |   Pubmed ID: 20599470
• Inflammatory Chemokine Release of Astrocytes in Vitro is Reduced by All-trans Retinoic Acid
  Journal of Neurochemistry. Sep, 2010  |   Pubmed ID: 20557428
• Microglia Promote Colonization of Brain Tissue by Breast Cancer Cells in a Wnt-dependent Way
  Glia. Sep, 2010  |   Pubmed ID: 20549749
• T Cell-dependence of Lassa Fever Pathogenesis
  PLoS Pathogens. Mar, 2010  |   Pubmed ID: 20360949
• Locus Ceruleus Controls Alzheimer's Disease Pathology by Modulating Microglial Functions Through Norepinephrine
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010  |   Pubmed ID: 20231476
• TRPM3 is Expressed in Sphingosine-responsive Myelinating Oligodendrocytes
  Journal of Neurochemistry. Aug, 2010  |   Pubmed ID: 20163522
• Toll-like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus Pneumoniae by Murine Microglia
  Infection and Immunity. Feb, 2010  |   Pubmed ID: 19933834
• Fibronectin Stimulates Escherichia Coli Phagocytosis by Microglial Cells
  Glia. Feb, 2010  |   Pubmed ID: 19780198
• Therapeutic and Adverse Effects of a Non-steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis
  PloS One. 2009  |   Pubmed ID: 19997594
• FK506 Protects Against Various Immune Responses and Secondary Degeneration Following Cerebral Ischemia
  Anatomical Record (Hoboken, N.J. : 2007). Dec, 2009  |   Pubmed ID: 19728359
• Toll-like Receptor Prestimulation Increases Phagocytosis of Escherichia Coli DH5alpha and Escherichia Coli K1 Strains by Murine Microglial Cells
  Infection and Immunity. Jan, 2009  |   Pubmed ID: 18981243
• Thrombin-induced Regulation of CD95(Fas) Expression in the N9 Microglial Cell Line: Evidence for Involvement of Proteinase-activated Receptor(1) and Extracellular Signal-regulated Kinase 1/2
  Neurochemical Research. Mar, 2009  |   Pubmed ID: 18686031
• Inhibition of Rho-dependent Pathways by Clostridium Botulinum C3 Protein Induces a Proinflammatory Profile in Microglia
  Glia. Aug, 2008  |   Pubmed ID: 18442097
• Distinct and Nonredundant in Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System
  Immunity. May, 2008  |   Pubmed ID: 18424188
• Thrombin Regulates CD40 Expression in Microglial Cells
  Neuroreport. May, 2008  |   Pubmed ID: 18418252
• Toll-like Receptors: Roles in Neuroprotection?
  Trends in Neurosciences. Apr, 2008  |   Pubmed ID: 18329736
• Myelin-phagocytosing Macrophages in Isolated Sciatic and Optic Nerves Reveal a Unique Reactive Phenotype
  Glia. Feb, 2008  |   Pubmed ID: 18069669
• Lipopolysaccharide is a Frequent and Significant Contaminant in Microglia-activating Factors
  Glia. Jan, 2008  |   Pubmed ID: 17910052
• Microglia in the Adult Brain Arise from Ly-6ChiCCR2+ Monocytes Only Under Defined Host Conditions
  Nature Neuroscience. Dec, 2007  |   Pubmed ID: 18026096
• Microglia: Active Sensor and Versatile Effector Cells in the Normal and Pathologic Brain
  Nature Neuroscience. Nov, 2007  |   Pubmed ID: 17965659
• Fibronectin is Elevated in the Cerebrospinal Fluid of Patients Suffering from Bacterial Meningitis and Enhances Inflammation Caused by Bacterial Products in Primary Mouse Microglial Cell Cultures
  Journal of Neurochemistry. Sep, 2007  |   Pubmed ID: 17561936
• A Paediatric Supratentorial Primitive Neuroectodermal Tumour Associated with Malignant Astrocytic Transformation and a Clonal Origin of Both Components
  Neurosurgical Review. Apr, 2007  |   Pubmed ID: 17333087
• Activation of Microglial Cells by Thrombin: Past, Present, and Future
  Seminars in Thrombosis and Hemostasis. Apr, 2006  |   Pubmed ID: 16673268
• Microglial Phenotype: is the Commitment Reversible?
  Trends in Neurosciences. Feb, 2006  |   Pubmed ID: 16406093
• Unraveling Thrombin's True Microglia-activating Potential: Markedly Disparate Profiles of Pharmaceutical-grade and Commercial-grade Thrombin Preparations
  Journal of Neurochemistry. Nov, 2005  |   Pubmed ID: 16271051
• C-Jun N-terminal Kinases (JNKs) Mediate Pro-inflammatory Actions of Microglia
  Glia. May, 2005  |   Pubmed ID: 15739188
• Microglia
  Metabolic Brain Disease. Dec, 2004  |   Pubmed ID: 15554430
• The Microglia-activating Potential of Thrombin: the Protease is Not Involved in the Induction of Proinflammatory Cytokines and Chemokines
  The Journal of Biological Chemistry. Dec, 2004  |   Pubmed ID: 15452111
• The Tyrosine Kinase Inhibitor AG126 Restores Receptor Signaling and Blocks Release Functions in Activated Microglia (brain Macrophages) by Preventing a Chronic Rise in the Intracellular Calcium Level
  Journal of Neurochemistry. Aug, 2004  |   Pubmed ID: 15255929
• Tyrosine Kinase Inhibition Reduces Inflammation in the Acute Stage of Experimental Pneumococcal Meningitis
  Infection and Immunity. Jun, 2004  |   Pubmed ID: 15155632
• Expression of Proteinase-activated Receptors in Mouse Microglial Cells
  Neuroreport. Dec, 2003  |   Pubmed ID: 14663194
• Purinergic Receptors on Microglial Cells: Functional Expression in Acute Brain Slices and Modulation of Microglial Activation in Vitro
  The European Journal of Neuroscience. Jun, 2003  |   Pubmed ID: 12814360
• Elevation of Basal Intracellular Calcium As a Central Element in the Activation of Brain Macrophages (microglia): Suppression of Receptor-evoked Calcium Signaling and Control of Release Function
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2003  |   Pubmed ID: 12805281
• Interferon-gamma Differentially Modulates the Release of Cytokines and Chemokines in Lipopolysaccharide- and Pneumococcal Cell Wall-stimulated Mouse Microglia and Macrophages
  The European Journal of Neuroscience. Dec, 2002  |   Pubmed ID: 12473079
• Microglia As a Source and Target of Cytokines
  Glia. Nov, 2002  |   Pubmed ID: 12379902