Vassiliki A. Boussiotis

Publications

• Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy
  Frontiers in Oncology. Month, 2018   |   Pubmed ID: 30123774
• Publisher Correction: Feeling Stressed? It Might Be Your T Cells
  Nature Immunology. Sep, 2018   |   Pubmed ID: 29955108
• Possible Reactivation of Chromosomally Integrated Human Herpesvirus 6 After Treatment with Histone Deacetylase Inhibitor
  Blood Advances. Jun, 2018   |   Pubmed ID: 29898877
• Immunotherapies for Malignant Glioma
  Oncogene. Mar, 2018   |   Pubmed ID: 29242608
• Feeling Stressed? It Might Be Your T Cells
  Nature Immunology. Nov, 2017   |   Pubmed ID: 29144505
• The Adaptor Molecule RIAM Integrates Signaling Events Critical for Integrin-mediated Control of Immune Function and Cancer Progression
  Science Signaling. Aug, 2017   |   Pubmed ID: 28831022
• Advances in the Pathophysiology and Treatment of Relapsed/refractory Hodgkin's Lymphoma with an Emphasis on Targeted Therapies and Transplantation Strategies
  Blood and Lymphatic Cancer : Targets and Therapy. Month, 2017   |   Pubmed ID: 28701859
• Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses
  Frontiers in Immunology. Month, 2017   |   Pubmed ID: 28443090
• Angiogenic Factors Correlate with T Cell Immune Reconstitution and Clinical Outcomes After Double-Unit Umbilical Cord Blood Transplantation in Adults
  Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. 01, 2017   |   Pubmed ID: 27777141
• JAK3-mediated Phosphorylation of EZH2: a Novel Mechanism of Non-canonical EZH2 Activation and Oncogenic Function
  Translational Cancer Research. Nov, 2016   |   Pubmed ID: 28868240
• The Role of Metabolic Reprogramming in T Cell Fate and Function
  Current Trends in Immunology. Month, 2016   |   Pubmed ID: 28356677
• The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation
  Frontiers in Immunology. Month, 2016   |   Pubmed ID: 28018338
• Epigenetic Regulation of Cancer Biology and Anti-tumor Immunity by EZH2
  Oncotarget. Dec, 2016   |   Pubmed ID: 27793053
• Corrigendum: Regulation of T Cell Differentiation and Function by EZH2
  Frontiers in Immunology. Month, 2016   |   Pubmed ID: 27648006
• Clinical Significance of T Cell Metabolic Reprogramming in Cancer
  Clinical and Translational Medicine. Dec, 2016   |   Pubmed ID: 27510264
• Regulation of T Cell Differentiation and Function by EZH2
  Frontiers in Immunology. Month, 2016   |   Pubmed ID: 27199994
• Cell-specific PD-L1 Expression in DLBCL
  Blood. Nov, 2015   |   Pubmed ID: 26542250
• PD-1 Alters T-cell Metabolic Reprogramming by Inhibiting Glycolysis and Promoting Lipolysis and Fatty Acid Oxidation
  Nature Communications. Mar, 2015   |   Pubmed ID: 25809635
• Somatic Mutations and Immunotherapy Outcome with CTLA-4 Blockade in Melanoma
  The New England Journal of Medicine. Dec, 2014   |   Pubmed ID: 25409261
• The Role of the Thymus in T-cell Immune Reconstitution After Umbilical Cord Blood Transplantation
  Blood. Nov, 2014   |   Pubmed ID: 25287708
• Biochemical Signaling of PD-1 on T Cells and Its Functional Implications
  Cancer Journal (Sudbury, Mass.). Jul-Aug, 2014   |   Pubmed ID: 25098287
• The Cyclin Dependent Kinase Inhibitor (R)-roscovitine Mediates Selective Suppression of Alloreactive Human T Cells but Preserves Pathogen-specific and Leukemia-specific Effectors
  Clinical Immunology (Orlando, Fla.). May-Jun, 2014   |   Pubmed ID: 24631965
• The Role of IL-17-producing Foxp3+ CD4+ T Cells in Inflammatory Bowel Disease and Colon Cancer
  Clinical Immunology (Orlando, Fla.). Aug, 2013   |   Pubmed ID: 23773923
• PD-1 Increases PTEN Phosphatase Activity While Decreasing PTEN Protein Stability by Inhibiting Casein Kinase 2
  Molecular and Cellular Biology. Aug, 2013   |   Pubmed ID: 23732914
• RIAM (Rap1-interacting Adaptor Molecule) Regulates Complement-dependent Phagocytosis
  Cellular and Molecular Life Sciences : CMLS. Jul, 2013   |   Pubmed ID: 23420480
• Rap1-interacting Adapter Molecule (RIAM) Associates with the Plasma Membrane Via a Proximity Detector
  The Journal of Cell Biology. Oct, 2012   |   Pubmed ID: 23045549
• PD-1 Inhibits T Cell Proliferation by Upregulating P27 and P15 and Suppressing Cdc25A
  Cell Cycle (Georgetown, Tex.). Dec, 2012   |   Pubmed ID: 23032366
• Runx1 and Runx3 Are Involved in the Generation and Function of Highly Suppressive IL-17-producing T Regulatory Cells
  PloS One. Month, 2012   |   Pubmed ID: 22984619
• Selective Effects of PD-1 on Akt and Ras Pathways Regulate Molecular Components of the Cell Cycle and Inhibit T Cell Proliferation
  Science Signaling. Jun, 2012   |   Pubmed ID: 22740686
• Molecular and Functional Heterogeneity of T Regulatory Cells
  Clinical Immunology (Orlando, Fla.). Dec, 2011   |   Pubmed ID: 21945485
• Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells
  The Journal of Biological Chemistry. May, 2011   |   Pubmed ID: 21454517
• Rap1A Regulates Generation of T Regulatory Cells Via LFA-1-dependent and LFA-1-independent Mechanisms
  Cellular Immunology. Month, 2010   |   Pubmed ID: 20864093
• IL-1β-mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17-producing Cells
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2010   |   Pubmed ID: 20817874
• RIAM Regulates the Cytoskeletal Distribution and Activation of PLC-gamma1 in T Cells
  Science Signaling. Dec, 2009   |   Pubmed ID: 19952372
• The Cyclin Dependent Kinase Inhibitor (R)-roscovitine Prevents Alloreactive T Cell Clonal Expansion and Protects Against Acute GvHD
  Cell Cycle (Georgetown, Tex.). Jun, 2009   |   Pubmed ID: 19448431
• Tob, a Member of the APRO Family, Regulates Immunological Quiescence and Tumor Suppression
  Cell Cycle (Georgetown, Tex.). Apr, 2009   |   Pubmed ID: 19270514
• Interleukin-4 Stimulates Proliferation and Growth of T-cell Acute Lymphoblastic Leukemia Cells by Activating MTOR Signaling
  Leukemia. Jan, 2009   |   Pubmed ID: 18596736
• The Nore1B/Mst1 Complex Restrains Antigen Receptor-induced Proliferation of Naïve T Cells
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008   |   Pubmed ID: 19073936
• Control and Regulation of Peripheral Tolerance in Allergic Inflammatory Disease: Therapeutic Consequences
  Chemical Immunology and Allergy. Month, 2008   |   Pubmed ID: 18802347
• CD134-allodepletion Allows Selective Elimination of Alloreactive Human T Cells Without Loss of Virus-specific and Leukemia-specific Effectors
  Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. May, 2008   |   Pubmed ID: 18410894
• Umbilical Cord Blood Transplantation: Basic Biology and Clinical Challenges to Immune Reconstitution
  Clinical Immunology (Orlando, Fla.). Jun, 2008   |   Pubmed ID: 18395491
• Twisted Gastrulation (Tsg) is Regulated by Tob and Enhances TGF-beta Signaling in Activated T Lymphocytes
  Blood. Apr, 2007   |   Pubmed ID: 17164348
• A Pathway Regulated by Cell Cycle Inhibitor P27Kip1 and Checkpoint Inhibitor Smad3 is Involved in the Induction of T Cell Tolerance
  Nature Immunology. Nov, 2006   |   Pubmed ID: 17013388
• Physiologic Regulation of Central and Peripheral T Cell Tolerance: Lessons for Therapeutic Applications
  Journal of Molecular Medicine (Berlin, Germany). Nov, 2006   |   Pubmed ID: 16972086
• CD28 Costimulation Mediates Transcription of SKP2 and CKS1, the Substrate Recognition Components of SCFSkp2 Ubiquitin Ligase That Leads P27kip1 to Degradation
  Cell Cycle (Georgetown, Tex.). Sep, 2006   |   Pubmed ID: 16969077
• Rap1 Regulation of RIAM and Cell Adhesion
  Methods in Enzymology. Month, 2006   |   Pubmed ID: 16757337
• Rap1-GTP is a Negative Regulator of Th Cell Function and Promotes the Generation of CD4+CD103+ Regulatory T Cells in Vivo
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2005   |   Pubmed ID: 16116203
• CD4+CD25+ Regulatory T-cell Lines from Human Cord Blood Have Functional and Molecular Properties of T-cell Anergy
  Blood. Nov, 2005   |   Pubmed ID: 16020508
• Common Gamma Chain-signaling Cytokines Promote Proliferation of T-cell Acute Lymphoblastic Leukemia
  Haematologica. Dec, 2004   |   Pubmed ID: 15590396
• RIAM, an Ena/VASP and Profilin Ligand, Interacts with Rap1-GTP and Mediates Rap1-induced Adhesion
  Developmental Cell. Oct, 2004   |   Pubmed ID: 15469846
• Activation of PI3K is Indispensable for Interleukin 7-mediated Viability, Proliferation, Glucose Use, and Growth of T Cell Acute Lymphoblastic Leukemia Cells
  The Journal of Experimental Medicine. Sep, 2004   |   Pubmed ID: 15353558
• IL-7-dependent Human Leukemia T-cell Line As a Valuable Tool for Drug Discovery in T-ALL
  Blood. Mar, 2004   |   Pubmed ID: 14615384
• Antigen-specific and Persistent Tuberculin Anergy in a Cohort of Pulmonary Tuberculosis Patients from Rural Cambodia
  Proceedings of the National Academy of Sciences of the United States of America. May, 2002   |   Pubmed ID: 12032325
• CD28 Costimulation Mediates Down-regulation of P27kip1 and Cell Cycle Progression by Activation of the PI3K/PKB Signaling Pathway in Primary Human T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2002   |   Pubmed ID: 11884439
• Blockade of B7/CD28 in Mixed Lymphocyte Reaction Cultures Results in the Generation of Alternatively Activated Macrophages, Which Suppress T-cell Responses
  Blood. Feb, 2002   |   Pubmed ID: 11830501
• CTLA-4 Regulates Cell Cycle Progression During a Primary Immune Response
  European Journal of Immunology. 02, 2002   |   Pubmed ID: 11807776