Vesa Hytönen Institute of Biomedical Technology University of Tampere Biography Publications Institution JoVE Articles Vesa Hytönen has not added a biography. If you are Vesa Hytönen and would like to personalize this page please email our Author Liaison for assistance. Publications A Novel Rat CVB1-VP1 Monoclonal Antibody 3A6 Detects a Broad Range of Enteroviruses Scientific Reports. Jan, 2018 | Pubmed ID: 29311608 A Coxsackievirus B Vaccine Protects Against Virus-induced Diabetes in an Experimental Mouse Model of Type 1 Diabetes Diabetologia. Feb, 2018 | Pubmed ID: 29151123 Identification and Characterization of a Novel Zebrafish (Danio Rerio) Pentraxin-carbonic Anhydrase PeerJ. 2017 | Pubmed ID: 29230365 Optimized Streptavidin for Fluorescent Labeling of Biotinylated Targets Cell Chemical Biology. 08, 2017 | Pubmed ID: 28820961 Mechanical Stability of Talin Rod Controls Cell Migration and Substrate Sensing Scientific Reports. Jun, 2017 | Pubmed ID: 28620171 3D-Printable Bioactivated Nanocellulose-Alginate Hydrogels ACS Applied Materials & Interfaces. Jul, 2017 | Pubmed ID: 28598154 Optimized Production and Purification of Coxsackievirus B1 Vaccine and Its Preclinical Evaluation in a Mouse Model Vaccine. Jun, 2017 | Pubmed ID: 28579231 Structural Characterization of Core-bradavidin in Complex with Biotin PloS One. 2017 | Pubmed ID: 28426764 The Molecular Basis of Talin2's High Affinity Toward β1-integrin Scientific Reports. Feb, 2017 | Pubmed ID: 28155884 Search for KPNA7 Cargo Proteins in Human Cells Reveals MVP and ZNF414 As Novel Regulators of Cancer Cell Growth Biochimica Et Biophysica Acta. Jan, 2017 | Pubmed ID: 27664836 Talin and Vinculin Are Downregulated in Atherosclerotic Plaque; Tampere Vascular Study Atherosclerosis. Dec, 2016 | Pubmed ID: 27816808 Toward Single Electron Nanoelectronics Using Self-Assembled DNA Structure Nano Letters. Nov, 2016 | Pubmed ID: 27700108 Talin2-mediated Traction Force Drives Matrix Degradation and Cell Invasion Journal of Cell Science. 10, 2016 | Pubmed ID: 27694340 Core-Shell Nanorod Columnar Array Combined with Gold Nanoplate-Nanosphere Assemblies Enable Powerful In Situ SERS Detection of Bacteria ACS Applied Materials & Interfaces. Sep, 2016 | Pubmed ID: 27574829 Improved Antifouling Properties and Selective Biofunctionalization of Stainless Steel by Employing Heterobifunctional Silane-polyethylene Glycol Overlayers and Avidin-biotin Technology Scientific Reports. Jul, 2016 | Pubmed ID: 27381834 All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing ACS Nano. Jul, 2016 | Pubmed ID: 27380548 Enteroviral Proteases: Structure, Host Interactions and Pathogenicity Reviews in Medical Virology. Jul, 2016 | Pubmed ID: 27145174 Horizontal Transfer of β-carbonic Anhydrase Genes from Prokaryotes to Protozoans, Insects, and Nematodes Parasites & Vectors. Mar, 2016 | Pubmed ID: 26983858 Artificial Avidin-Based Receptors for a Panel of Small Molecules ACS Chemical Biology. Jan, 2016 | Pubmed ID: 26550684 Biolayer Interferometry: A Novel Method to Elucidate Protein-Protein and Protein-DNA Interactions in the Mitochondrial DNA Replisome Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26530686 Mechanosensing in Cell-matrix Adhesions - Converting Tension into Chemical Signals Experimental Cell Research. 04, 2016 | Pubmed ID: 26518118 Improving the Immunogenicity of the Mycobacterium Bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System PloS One. 2015 | Pubmed ID: 26716832 PIP2 and Talin Join Forces to Activate Integrin The Journal of Physical Chemistry. B. Sep, 2015 | Pubmed ID: 26309152 Kindlin 3 (FERMT3) is Associated with Unstable Atherosclerotic Plaques, Anti-inflammatory Type II Macrophages and Upregulation of Beta-2 Integrins in All Major Arterial Beds Atherosclerosis. Sep, 2015 | Pubmed ID: 26188538 His-tagged Norovirus-like Particles: A Versatile Platform for Cellular Delivery and Surface Display European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V. Oct, 2015 | Pubmed ID: 26170162 The Minor Capsid Protein VP11 of Thermophilic Bacteriophage P23-77 Facilitates Virus Assembly by Using Lipid-Protein Interactions Journal of Virology. Aug, 2015 | Pubmed ID: 25972558 Enhancement of Adhesion and Promotion of Osteogenic Differentiation of Human Adipose Stem Cells by Poled Electroactive Poly(vinylidene Fluoride) Journal of Biomedical Materials Research. Part A. Mar, 2015 | Pubmed ID: 24838756 Switchavidin: Reversible Biotin-avidin-biotin Bridges with High Affinity and Specificity Bioconjugate Chemistry. Dec, 2014 | Pubmed ID: 25405260 The Talin-integrin Interface Under Mechanical Stress Molecular BioSystems. Dec, 2014 | Pubmed ID: 25277990 Beta Carbonic Anhydrases: Novel Targets for Pesticides and Anti-parasitic Agents in Agriculture and Livestock Husbandry Parasites & Vectors. Aug, 2014 | Pubmed ID: 25174433 Global Analysis of Human Nonreceptor Tyrosine Kinase Specificity Using High-density Peptide Microarrays Journal of Proteome Research. Oct, 2014 | Pubmed ID: 25164267 PH-dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy Molecules (Basel, Switzerland). Aug, 2014 | Pubmed ID: 25153869 Chimeric Avidin--NMR Structure and Dynamics of a 56 KDa Homotetrameric Thermostable Protein PloS One. 2014 | Pubmed ID: 24959850 Molecular Engineering of Avidin and Hydrophobin for Functional Self-assembling Interfaces Colloids and Surfaces. B, Biointerfaces. Aug, 2014 | Pubmed ID: 24905684 Talin-bound NPLY Motif Recruits Integrin-signaling Adapters to Regulate Cell Spreading and Mechanosensing The Journal of Cell Biology. Apr, 2014 | Pubmed ID: 24778313 A Novel Chimeric Avidin with Increased Thermal Stability Using DNA Shuffling PloS One. 2014 | Pubmed ID: 24632863 Coxsackievirus B3 VLPs Purified by Ion Exchange Chromatography Elicit Strong Immune Responses in Mice Antiviral Research. Apr, 2014 | Pubmed ID: 24485896 Protein Conformation As a Regulator of Cell-matrix Adhesion Physical Chemistry Chemical Physics : PCCP. Apr, 2014 | Pubmed ID: 24469063 Zebavidin--an Avidin-like Protein from Zebrafish PloS One. 2013 | Pubmed ID: 24204770 Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7) is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor β1a (TGFβ1a) The Journal of Biological Chemistry. Dec, 2013 | Pubmed ID: 24178295 Association of Neuroimmune Guidance Cue Netrin-1 and Its Chemorepulsive Receptor UNC5B with Atherosclerotic Plaque Expression Signatures and Stability in Human(s): Tampere Vascular Study (TVS) Circulation. Cardiovascular Genetics. Dec, 2013 | Pubmed ID: 24122613 The Highly Dynamic Oligomeric Structure of Bradavidin II is Unique Among Avidin Proteins Protein Science : a Publication of the Protein Society. Jul, 2013 | Pubmed ID: 23661323 Peptide-functionalized Chitosan-DNA Nanoparticles for Cellular Targeting Carbohydrate Polymers. Jul, 2012 | Pubmed ID: 24750885 GFP's Mechanical Intermediate States PloS One. 2012 | Pubmed ID: 23118864 Structure of Bradavidin-C-terminal Residues Act As Intrinsic Ligands PloS One. 2012 | Pubmed ID: 22574129 DNA Family Shuffling Within the Chicken Avidin Protein Family - A Shortcut to More Powerful Protein Tools Journal of Biotechnology. Jan, 2012 | Pubmed ID: 22100264 A Comparison of Immunogenicity of Norovirus GII-4 Virus-like Particles and P-particles Immunology. Jan, 2012 | Pubmed ID: 22044070 Production and Characterization of Virus-like Particles and the P Domain Protein of GII.4 Norovirus Journal of Virological Methods. Jan, 2012 | Pubmed ID: 21600929 Identification of Proprotein Convertase Substrates Using Genome-wide Expression Correlation Analysis BMC Genomics. Dec, 2011 | Pubmed ID: 22185580 Acetaldehyde-derived Modifications on Cytosolic Human Carbonic Anhydrases Journal of Enzyme Inhibition and Medicinal Chemistry. Dec, 2011 | Pubmed ID: 21679053 Modification of the Loops in the Ligand-binding Site Turns Avidin into a Steroid-binding Protein BMC Biotechnology. Jun, 2011 | Pubmed ID: 21658230 Construction of Chimeric Dual-chain Avidin by Tandem Fusion of the Related Avidins PloS One. 2011 | Pubmed ID: 21655240 Bifunctional Avidin with Covalently Modifiable Ligand Binding Site PloS One. Jan, 2011 | Pubmed ID: 21305032 Chimeric Avidin Shows Stability Against Harsh Chemical Conditions--biochemical Analysis and 3D Structure Biotechnology and Bioengineering. Mar, 2011 | Pubmed ID: 20939005 Characterization of the First Beta-class Carbonic Anhydrase from an Arthropod (Drosophila Melanogaster) and Phylogenetic Analysis of Beta-class Carbonic Anhydrases in Invertebrates BMC Biochemistry. Jul, 2010 | Pubmed ID: 20659325 Analysis of a Shortened Form of Human Carbonic Anhydrase VII Expressed in Vitro Compared to the Full-length Enzyme Biochimie. Aug, 2010 | Pubmed ID: 20493921 Rational Modification of Ligand-binding Preference of Avidin by Circular Permutation and Mutagenesis Chembiochem : a European Journal of Chemical Biology. May, 2008 | Pubmed ID: 18381715 Internalization of Novel Non-viral Vector TAT-streptavidin into Human Cells BMC Biotechnology. Jan, 2007 | Pubmed ID: 17199888 Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System Ting-Yu Angela Liao1, Alice Lau1, Joseph Sunil1, Vesa Hytönen2, Zakaria Hmama1 1Division of Infectious Diseases, Department of Medicine and Vancouver Costal Health Research Institute, University of British Columbia, 2Institute of Biomedical Technology, University of Tampere JoVE 56421 Immunology and Infection
Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System Ting-Yu Angela Liao1, Alice Lau1, Joseph Sunil1, Vesa Hytönen2, Zakaria Hmama1 1Division of Infectious Diseases, Department of Medicine and Vancouver Costal Health Research Institute, University of British Columbia, 2Institute of Biomedical Technology, University of Tampere JoVE 56421 Immunology and Infection
