Viacheslav O. Nikolaev DZHK (German Center for Cardiovascular Research) Biography Publications Institution JoVE Articles Viacheslav O. Nikolaev has not added a biography. If you are Viacheslav O. Nikolaev and would like to personalize this page please email our Author Liaison for assistance. Publications High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β2-Adrenergic Receptor/Gi-Dependent Manner: A New Model of Takotsubo Cardiomyopathy Circulation. Aug, 2012 | Pubmed ID: 22732314 DT-2 is a Specific PKG I Inhibitor Only in Vitro, but Not in a Living Cells British Journal of Pharmacology. May, 2012 | Pubmed ID: 22612416 Plasticity of Surface Structures and β(2)-adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery from Heart Failure Circulation. Heart Failure. May, 2012 | Pubmed ID: 22456061 Popeye Domain Containing Proteins Are Essential for Stress-mediated Modulation of Cardiac Pacemaking in Mice The Journal of Clinical Investigation. Mar, 2012 | Pubmed ID: 22354168 Atrial Natriuretic Peptide Enhances Microvascular Albumin Permeability by the Caveolae-mediated Transcellular Pathway Cardiovascular Research. Jan, 2012 | Pubmed ID: 22025581 Low Angle Light Scattering Analysis: a Novel Quantitative Method for Functional Characterization of Human and Murine Platelet Receptors Clinical Chemistry and Laboratory Medicine : CCLM / FESCC. Dec, 2011 | Pubmed ID: 22149738 A Cardiac Pathway of Cyclic GMP-independent Signaling of Guanylyl Cyclase A, the Receptor for Atrial Natriuretic Peptide Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22027011 A Protective Antiarrhythmic Role of Ursodeoxycholic Acid in an in Vitro Rat Model of the Cholestatic Fetal Heart Hepatology (Baltimore, Md.). Oct, 2011 | Pubmed ID: 21809354 FRET Measurements of Intracellular CAMP Concentrations and CAMP Analog Permeability in Intact Cells Nature Protocols. Apr, 2011 | Pubmed ID: 21412271 Endocytosis in the Mouse Oocyte and Its Contribution to CAMP Signaling During Meiotic Arrest Reproduction (Cambridge, England). Jun, 2011 | Pubmed ID: 21411693 Distinct Pharmacological Properties of Morphine Metabolites at G(i)-protein and β-arrestin Signaling Pathways Activated by the Human μ-opioid Receptor Biochemical Pharmacology. May, 2011 | Pubmed ID: 21396918 Scanning Ion Conductance Microscopy: a Convergent High-resolution Technology for Multi-parametric Analysis of Living Cardiovascular Cells Journal of the Royal Society, Interface / the Royal Society. Jul, 2011 | Pubmed ID: 21325316 Epidermal Growth Factor Receptor Kinase Activity is Required for Gap Junction Closure and for Part of the Decrease in Ovarian Follicle CGMP in Response to LH Reproduction (Cambridge, England). Nov, 2010 | Pubmed ID: 20826538 Real-time Monitoring of Somatostatin Receptor-cAMP Signaling in Live Pituitary Endocrinology. Sep, 2010 | Pubmed ID: 20610560 Type 4 Phosphodiesterase Plays Different Integrating Roles in Different Cellular Domains in Pyramidal Cortical Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2010 | Pubmed ID: 20427672 Imaging of Persistent CAMP Signaling by Internalized G Protein-coupled Receptors Journal of Molecular Endocrinology. Jul, 2010 | Pubmed ID: 20378719 Signaling by Internalized G-protein-coupled Receptors Trends in Pharmacological Sciences. May, 2010 | Pubmed ID: 20303186 Bile Acid-induced Arrhythmia is Mediated by Muscarinic M2 Receptors in Neonatal Rat Cardiomyocytes PloS One. 2010 | Pubmed ID: 20300620 Beta2-adrenergic Receptor Redistribution in Heart Failure Changes CAMP Compartmentation Science (New York, N.Y.). Mar, 2010 | Pubmed ID: 20185685 A Fluorescence Resonance Energy Transfer-based M2 Muscarinic Receptor Sensor Reveals Rapid Kinetics of Allosteric Modulation The Journal of Biological Chemistry. Mar, 2010 | Pubmed ID: 20083608 Distinct Pools of CAMP Centre on Different Isoforms of Adenylyl Cyclase in Pituitary-derived GH3B6 Cells Journal of Cell Science. Jan, 2010 | Pubmed ID: 20016070 Gq-mediated Ca2+ Signals Inhibit Adenylyl Cyclases 5/6 in Vascular Smooth Muscle Cells American Journal of Physiology. Cell Physiology. Feb, 2010 | Pubmed ID: 19889965 Persistent CAMP-signals Triggered by Internalized G-protein-coupled Receptors PLoS Biology. Aug, 2009 | Pubmed ID: 19688034 A Technique for Monitoring Multiple Signals with a Combination of Prism-based Total Internal Reflection Fluorescence Microscopy and Epifluorescence Microscopy Pflügers Archiv : European Journal of Physiology. Nov, 2009 | Pubmed ID: 19680684 Cyclic GMP from the Surrounding Somatic Cells Regulates Cyclic AMP and Meiosis in the Mouse Oocyte Development (Cambridge, England). Jun, 2009 | Pubmed ID: 19429786 Sweet Taste Receptor Expressed in Pancreatic Beta-cells Activates the Calcium and Cyclic AMP Signaling Systems and Stimulates Insulin Secretion PloS One. 2009 | Pubmed ID: 19352508 GPCR and G Proteins: Drug Efficacy and Activation in Live Cells Molecular Endocrinology (Baltimore, Md.). May, 2009 | Pubmed ID: 19196832 Novel Techniques for Real-time Monitoring of CGMP in Living Cells Handbook of Experimental Pharmacology. 2009 | Pubmed ID: 19089332 Alternative Splicing of the Guanylyl Cyclase-A Receptor Modulates Atrial Natriuretic Peptide Signaling The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18713751 Multidrug Resistance-associated Protein 4 Regulates CAMP-dependent Signaling Pathways and Controls Human and Rat SMC Proliferation The Journal of Clinical Investigation. Aug, 2008 | Pubmed ID: 18636120 Immunoadsorption in a 40 Year Old Man with Dilated Cardiomyopathy and Underlying Active Myocarditis Clinical Research in Cardiology : Official Journal of the German Cardiac Society. Oct, 2008 | Pubmed ID: 18633566 Cytoplasmic CAMP Concentrations in Intact Cardiac Myocytes American Journal of Physiology. Cell Physiology. Aug, 2008 | Pubmed ID: 18550706 Real-time Monitoring of Phosphodiesterase Inhibition in Intact Cells Cellular Signalling. Aug, 2008 | Pubmed ID: 18467075 Widespread Receptivity to Neuropeptide PDF Throughout the Neuronal Circadian Clock Network of Drosophila Revealed by Real-time Cyclic AMP Imaging Neuron. Apr, 2008 | Pubmed ID: 18439407 Spatiotemporal Dynamics of Beta-adrenergic CAMP Signals and L-type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes: Role of Phosphodiesterases Circulation Research. May, 2008 | Pubmed ID: 18369156 Optical Techniques to Analyze Real-time Activation and Signaling of G-protein-coupled Receptors Trends in Pharmacological Sciences. Mar, 2008 | Pubmed ID: 18262662 Conformational Cross-talk Between Alpha2A-adrenergic and Mu-opioid Receptors Controls Cell Signaling Nature Chemical Biology. Feb, 2008 | Pubmed ID: 18193048 Monitoring Receptor Signaling by Intramolecular FRET Current Opinion in Pharmacology. Oct, 2007 | Pubmed ID: 17919975 Kinetic Analysis of G Protein-coupled Receptor Signaling Using Fluorescence Resonance Energy Transfer in Living Cells Advances in Protein Chemistry. 2007 | Pubmed ID: 17854658 A Novel Fluorescence Method for the Rapid Detection of Functional Beta1-adrenergic Receptor Autoantibodies in Heart Failure Journal of the American College of Cardiology. Jul, 2007 | Pubmed ID: 17662395 Live Cell Monitoring of Mu-opioid Receptor-mediated G-protein Activation Reveals Strong Biological Activity of Close Morphine Biosynthetic Precursors The Journal of Biological Chemistry. Sep, 2007 | Pubmed ID: 17616524 CAMP Microdomains and L-type Ca2+ Channel Regulation in Guinea-pig Ventricular Myocytes The Journal of Physiology. May, 2007 | Pubmed ID: 17289786 Real-time Optical Recording of Beta1-adrenergic Receptor Activation Reveals Supersensitivity of the Arg389 Variant to Carvedilol The Journal of Clinical Investigation. Jan, 2007 | Pubmed ID: 17200720 Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-reaching Beta1-adrenergic but Locally Confined Beta2-adrenergic Receptor-mediated Signaling Circulation Research. Nov, 2006 | Pubmed ID: 17038640 Simultaneous Optical Measurements of Cytosolic Ca2+ and CAMP in Single Cells Science's STKE : Signal Transduction Knowledge Environment. Sep, 2006 | Pubmed ID: 16985238 Gs Activation is Time-limiting in Initiating Receptor-mediated Signaling The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 16963443 Molecular Basis of Partial Agonism at the Neurotransmitter Alpha2A-adrenergic Receptor and Gi-protein Heterotrimer The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16787921 Monitoring of CAMP Synthesis and Degradation in Living Cells Physiology (Bethesda, Md.). Apr, 2006 | Pubmed ID: 16565474 Fluorescent Sensors for Rapid Monitoring of Intracellular CGMP Nature Methods. Jan, 2006 | Pubmed ID: 16369548 Turn-on Switch in Parathyroid Hormone Receptor by a Two-step Parathyroid Hormone Binding Mechanism Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16236727 Interplay of Ca2+ and CAMP Signaling in the Insulin-secreting MIN6 Beta-cell Line The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 15987680 Real-time Monitoring of the PDE2 Activity of Live Cells: Hormone-stimulated CAMP Hydrolysis is Faster Than Hormone-stimulated CAMP Synthesis The Journal of Biological Chemistry. Jan, 2005 | Pubmed ID: 15557342 Novel Single Chain CAMP Sensors for Receptor-induced Signal Propagation The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15231839 Impact van Intracardiac neuronen op cardiale electrofysiologie en Arrhythmogenesis in een Ex Vivo Langendorff systeem Christiane Jungen1,2, Katharina Scherschel1,2, Nadja I. Bork2,3, Pawel Kuklik1, Christian Eickholt1, Helge Kniep1, Niklas Klatt1,2, Stephan Willems1,2, Viacheslav O. Nikolaev2,3, Christian Meyer1,2 1Department of Cardiology-Electrophysiology, cNEP (cardiac Neuro- and Electrophysiology research group), University Heart Center, University Hospital Hamburg-Eppendorf, 2DZHK (German Center for Cardiovascular Research), 3Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf JoVE 57617 Medicine FRET microscopie voor Real-time monitoring van Signalering Evenementen in levende cellen met behulp Unimoleculaire Biosensoren Julia U. Sprenger1, Ruwan K. Perera1, Konrad R. Götz1, Viacheslav O. Nikolaev1 1Emmy Noether Group of the DFG, Department of Cardiology and Pneumology, European Heart Research Insitute Göttingen, Georg August University Medical Center, Göttingen, Germany JoVE 4081 Biology
Impact van Intracardiac neuronen op cardiale electrofysiologie en Arrhythmogenesis in een Ex Vivo Langendorff systeem Christiane Jungen1,2, Katharina Scherschel1,2, Nadja I. Bork2,3, Pawel Kuklik1, Christian Eickholt1, Helge Kniep1, Niklas Klatt1,2, Stephan Willems1,2, Viacheslav O. Nikolaev2,3, Christian Meyer1,2 1Department of Cardiology-Electrophysiology, cNEP (cardiac Neuro- and Electrophysiology research group), University Heart Center, University Hospital Hamburg-Eppendorf, 2DZHK (German Center for Cardiovascular Research), 3Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf JoVE 57617 Medicine
FRET microscopie voor Real-time monitoring van Signalering Evenementen in levende cellen met behulp Unimoleculaire Biosensoren Julia U. Sprenger1, Ruwan K. Perera1, Konrad R. Götz1, Viacheslav O. Nikolaev1 1Emmy Noether Group of the DFG, Department of Cardiology and Pneumology, European Heart Research Insitute Göttingen, Georg August University Medical Center, Göttingen, Germany JoVE 4081 Biology
